Future projections of temperature-related indices in Prince Edward Island using ensemble average of three CMIP6 models.

Prince Edward Island (PEI) is an agricultural province heavily relying on rainfed agriculture. The island has already experienced significant impacts from climate change. Accurate projections of PEI temperature extreme indices are required to mitigate and adapt to the changing climate conditions. This study aims to develop ensemble projections using Coupled Model Intercomparison Project Phase 6 (CMIP6) global circulation models (GCMs) to analyze temperature extremes on PEI. In this study, the ECMWF ERA5 reanalysis dataset was chosen for stepwise cluster analysis (SCA) due to its high accuracy. Three CMIP6 (NorESM2-MM, MPI-ESM1.2-HR, and CanESM5) GCMs, along with their ensemble average, were utilized in the SCA model to project future changes in daily maximum temperature (Tmax) and minimum temperature (Tmin) at four meteorological stations on PEI (East Point, Charlottetown, Summerside, and North Cape) under two shared socioeconomic pathways (SSP2-4.5 and SSP5-8.5). These GCMs were selected based on their low, medium, and high Equilibrium Climate Sensitivity. The bias-corrected results for the future period of Tmax and Tmin showed that the GCM-specific changes in the ECS also impact the regional scale. Additionally, several temperature extreme indices, including the daily temperature range (DTR), summer days (SU), growing degree days (GDD), growing season length (GSL), ice days (ID), and frost days (FD), were analyzed for two future periods: FP1(202-2050) and FP2 (2051-2075). The results indicate that DTR, SU, GDD, and GSL are expected to increase, while ID and FD are projected to decrease during FP1 and FP2 under both scenarios. The future projected mean monthly changes in Tmax, Tmin, and the selected temperature extreme indices highlight warmer future periods and an increase in agriculture-related indices such as GDD and GSL. Specifically, July, August, and September are expected to experience even higher temperatures in the future. As the climate becomes warmer, cold extreme events are projected to be shorter in duration but more intense in terms of their impact. The largest increments/decrements for Tmax, Tmin, and their relevant indices were observed during FP2 under SSP5-8.5. The outcomes of this study provide valuable insights for agricultural development, water resource management, and the formulation of effective mitigation strategies to address the impacts of climate change on PEI.

Stroke hospitalizations, posttraumatic stress disorder, and 9/11-related dust exposure: Results from the World Trade Center Health Registry.

BACKGROUND: Few studies have examined the association between disaster-related factors and stroke by subtype or number. We investigated the association between 9/11-related posttraumatic stress disorder (PTSD), dust exposure, and stroke subtype as well as recurrent strokes. METHODS: The study included 29,012 individuals enrolled in the World Trade Center Health Registry. Stroke cases were obtained by matching Registry enrollees to the New York State Department of Health's discharge records for inpatient visits between 2000 and 2016. Cox proportional hazards regression models were performed to examine the association between 9/11-related risk factors and stroke by subtype. Multinomial logistic regression models were conducted to assess the associations between the same risk factors and the number of stroke hospitalizations. RESULTS: Having PTSD significantly increased the risk of developing ischemic and hemorrhagic stroke, with adjusted hazards ratios (AHRs) of 1.64 (95% confidence interval [CI]: 1.28-2.10) and 1.73 (95% CI: 1.10-2.71), respectively. The point estimate for dust cloud exposure, although not significant statistically, suggested an increased risk of ischemic stroke (AHR = 1.20, 95% CI: 0.96-1.50). PTSD was significantly associated with recurrent strokes with an adjusted odds ratio of 1.79 (95% CI: 1.09-2.95). CONCLUSIONS: PTSD is a risk factor for both ischemic and hemorrhagic stroke and is associated with recurrent strokes. Dust exposure on 9/11 is a possible risk factor for ischemic stroke but not for hemorrhagic stroke, and was not associated with recurrent strokes. Our findings warrant additional research on stroke-morbidity and mortality associated with 9/11-related PTSD and dust exposure.

Effects of 9/11-related injury on retirement patterns among World Trade Center Health Registry enrollees.

BACKGROUND: Many survivors of the 9/11/2001 terrorist attacks in New York City sustained injuries. The aim of this study was to understand how 9/11-related injuries affected retirement patterns of World Trade Center Health Registry enrollees. METHODS: The study included enrollees who participated in the 2017 Health & Quality of Life Survey, focused on 9/11-related injuries and quality of life, and the 2017-2018 Health & Employment Survey, focused on retirement and employment (N = 3535). Using Cox proportional hazards and logistic regression modeling, we calculated the risk of retiring at earlier ages and the odds of retirees working again, controlling for relevant covariates. RESULTS: Results showed that 9/11-related injuries did affect retirement patterns. Injured enrollees were at greater risk of retiring at younger age compared to non-injured enrollees. Compared to more severely injured retirees, non-injured and less severely injured retirees were significantly more likely to work again postretirement. Our results suggested that being injured on 9/11 was associated with retirement, meaning that if the injury had not occurred, the individual may have continued working longer. CONCLUSIONS: The need to retire earlier than planned could be addressed with employer and societal changes. Employers should consider making accommodations for those impacted by 9/11 a priority, as it is imperative for those who were injured on 9/11 to have the ability to work to support their physical, mental, and financial well-being.

Impact of Health on Early Retirement and Post-Retirement Income Loss among Survivors of the 11 September 2001 World Trade Center Disaster.

The health consequences of the 9/11 World Trade Center (WTC) terrorist attacks are well documented, but few studies have assessed the disaster's impact on employment among individuals exposed to the disaster. We examined the association between 9/11-related health conditions and early retirement among residents and workers who resided and/or worked near the WTC site on 9/11, and the association between such conditions and post-retirement income loss. The study included 6377 residents and/or area workers who completed the WTC Health Registry longitudinal health surveys in 2003-2004 and 2006-2007, and the 2017-2018 Health and Employment Survey. Logistic regression models were used to examine the associations. We found that 9/11-related health conditions were significantly associated with the likelihood of early retirement. Residents and/or area workers with more physical health conditions, especially when comorbid with posttraumatic stress disorder (PTSD), were more likely to retire before age 60 than those with no conditions. For retirees, having PTSD or PTSD comorbid with any number of physical conditions increased the odds of reporting substantial post-retirement income loss. Disaster-related outcomes can negatively impact aging individuals in the form of early retirement and income loss. Long-term effects of major disasters must continue to be studied.

Biomonitoring programs in Michigan, Minnesota and New York to assess human exposure to Great Lakes contaminants.

Over the past century, industrialization and urban practices have resulted in the contamination of the Great Lakes ecosystem-the world's largest surface freshwater system-that provides drinking water and recreation to more than 40 million residents. In 2010, the Great Lakes Restoration Initiative was launched to accelerate efforts to protect and restore the Great Lakes and surrounding areas. Funded by GLRI, the Agency for Toxic Substances and Disease Registry initiated the Biomonitoring of Great Lakes Populations (BGLP) program. The objective of the program is to assess human exposure to legacy and emerging contaminants in the Great Lakes by measuring the body burden of contaminants in potentially susceptible populations. The BGLP program consists of a series of cross-sectional studies carried out collaboratively with states that are funded through ATSDR. The first BGLP Program (BGLP-I) began in 2010 and was completed in September 2015 through cooperative agreements with state health departments in Michigan, Minnesota, and New York. The three state programs targeted susceptible adult populations living in designated areas of contamination. Contaminants measured in all populations include mercury, lead, mirex, hexachlorobenzene, dichlorodiphenyltrichloroethane, and selected polychlorinated biphenyl congeners. In addition, some chemicals of emerging concern, such as per- and polyfluoroalkyl substances, were measured in several populations. The biomonitoring results helped guide public health actions to mitigate chemical exposures in these vulnerable Great Lakes populations. We provide an overview of the BGLP-I program's study populations, designs, and general methods. This overview provides a lead-in for subsequent manuscripts that present human biomonitoring data for legacy and emerging contaminants in culturally diverse susceptible populations-i.e., shoreline anglers, sport anglers, American Indians, and Burmese immigrants-residing in seven areas of concern.

Deciphering physio-biochemical, yield, and nutritional quality attributes of water-stressed radish (Raphanus sativus L.) plants grown from Zn-Lys primed seeds.

Water shortage appears to be expedited under the current climate change scenario worldwide. The present work was aimed to investigate the effects of zinc-chelated lysine (Zn-Lys) on germination and yield of water stressed radish plants. The research was comprised of two studies where the effect of Zn-Lys seed priming on germination attributes under PEG-induced water stress was investigated in the first experiment. In the second experiment, growth, physio-biochemical, and yield responses of water-stressed radish plants raised from Zn-Lys primed seeds were recorded. The seeds pre-conditioned with 0, 1.5, 3, 4.5, or 6 mg kg-1 of Zn-Lys was grown in petri-dishes and pots. Priming treatments significantly improved the germination attributes under water stress. Plants raised from primed seeds exhibited significant improvements in plant biomass production, leaf photosynthetic pigments, final root yield, and nutritional quality. Furthermore, the activities of superoxide dismutase (SOD) and peroxidase (POD) were increased, while the melondialdehyde (MDA) content decreased. Root flavonoids, ascorbic acid, carotenoids, protein, carbohydrates, fiber and lysine content were significantly improved due to Zn-Lys seed priming, both under water-stressed and non-stressed conditions. Moreover, plant's mineral nutrients such as K and Ca as well as Mg, Fe, P, and Zn of final harvested roots were also improved due to Zn-Lys seed priming. Overall, for the induction of drought tolerance and nutritional quality, Zn-Lys regimes of 3 and 4.5 mg kg-1 were most effective. It can be inferred that the Zn-Lys priming maintained a potential balance of nutrient uptake and translocation by preventing drought-induced lipid peroxidation of membranes.