Effectiveness of treatment of arterial hypertension in Central Europe from 1972 to 2022.

BACKGROUND: Hypertension is a leading cause of cardiovascular disease. This review examines the literature on hypertension control in the Czech Republic from 1972 to 2022 addressing limited data on its effectiveness. METHODS: A literature review was conducted covering the period from 1972 to 2022, utilizing MEDLINE (PubMed), Web of Science, and Scopus databases. Articles were selected based on title and abstract evaluations, with full-text reviews performed as needed. Thirteen studies involving 44,990 participants were included in this review. RESULTS: Control rates increased from 2.8% (men) and 5.2% (women) in 1985 to 32.3% (men) and 37.4% (women) from 2015 to 2018. Women showed better blood pressure control. Specialised centres achieved higher success (48%) than general practitioners (18.4%). Diabetic patients had a lower percentage (29.1%) of patients meeting their target values (<130/80 mmHg) compared to non-diabetic patients, who had a higher percentage (60.6%) meeting their target values (<140/90 mmHg). CONCLUSION: Hypertension treatment success rate in the Czech Republic improved significantly over the last 50 years and is currently comparable to that of other European countries with similar healthcare resources. However, it still remains suboptimal and lags behind the countries with the most successful treatment outcomes (Tab. 3, Fig. 1, Ref. 37). Text in PDF www.elis.sk Keywords: hypertension, treatment, effectiveness, Czech Republic, blood pressure.

Cascade of care for hypertension among apparently healthy and unhealthy individuals of 25-64 years in the Czech Republic.

BACKGROUND: Despite accessible diagnostics and treatment of hypertension, a high proportion of patients worldwide remain unaware of their diagnosis, and even more remain untreated. Several studies suggest that absence of comorbidities is a predictive factor for unawareness and consequently non-treatment of hypertension. There are only a few studies that have assessed the hypertension prevalence and management among apparently healthy individuals. OBJECTIVE: The aim of the study was to assess and compare hypertension prevalence, awareness, treatment and control among apparently healthy individuals, patients with internal diseases, and patients with non-internal diseases. METHODS: Data from standardised blood pressure measurements conducted during the Czech European Health Examination Survey 2014 and information on health status and health care use collected during the Czech European Health Interview Survey 2014 were analyzed. We focused on participants aged 25-64. Data were weighted on sex and age to ensure an appropriate sex and age structure of the population. The χ2-test and binary logistic regression analyses were used to compare distribution of cascade of care for hypertension between the health-status groups of respondents. RESULTS: The final eligible sample consisted of 1121 participants. The prevalence of hypertension was 32.8% in the healthy group, 29.8% in the non-internal disease group and 52.4% in the internal disease group, (p < 0.001). Awareness was 54.1%, 59.1% and 85.2% respectively, (p < 0.001). Treatment was 44.2%, 52.6% and 86.4%, respectively, (p < 0.001). Among apparently healthy respondents 62.6% had their blood pressure measured by a medical professional in the last year, compared to 71.1% in the non-internal disease group and 91.7% in the internal disease group, (p < 0.001). Differences in hypertension control were not statistically significant. CONCLUSIONS: Generally, our data show a discordance in hypertension management within the Czech population. Apparently healthy individuals are the least aware of their diagnosis and the highest proportion of them remain untreated.

Sugar-sweetened beverages and childhood abnormal adiposity in the Czech Republic - narrative literature review.

OBJECTIVES: In Czech children, the burden related to the high body-mass index is rising. In the last three decades, Western eating patterns have influenced Czech children's diet, including the high consumption of sugar-sweetened beverages. This narrative review aims to evaluate evidence of the trend of sugar-sweetened beverages consumption in Czech children and its impact on the prevalence of childhood abnormal adiposity. METHODS: A comprehensive literature review in MEDLINE (PubMed) and a hand search using references in identified articles were performed. The inclusion criteria were population-based studies of randomly selected samples of children from 0 to 18 years old, data involving the Czech population, published from 1990 to 2021. The results were organized into three sections - childhood abnormal adiposity, SSBs consumption, and the association between SSBs consumption and abnormal adiposity. RESULTS: The studies showed a significant increase in abnormal adiposity in both genders and all age categories. The highest prevalence of abnormal adiposity was observed in boys and younger children. On the contrary, sugar-sweetened beverages showed a significant decline in daily consumption among Czech children of both genders and all age categories. No results were found for consequences of abnormal adiposity concerning sugar-sweetened beverages consumption. CONCLUSION: Findings from this review could serve public health experts to detect the areas of a gap in research and establish potential interventions in vulnerable groups. Observation of potential obesogenic contributors - including sugar-sweetened beverages - should be an integral part of effective action against the obesity pandemic.

Comparison of social gradient in cardiometabolic health in Czechia and Venezuela: a cross-sectional study.

OBJECTIVES: This study compared the relationships of social determinants with cardiometabolic risk in different socioeconomic contexts: sociopolitically unstable Venezuela (VE) and stable Czechia (CZ). DESIGN: cross-sectional analysis involving two population-based studies. SETTING: Brno, Czechia and 23 cities of Venezuela. PARTICIPANTS: 25-64 years old subjects from CZ (2013-2014, n=1579, 56% females) and VE (2014-2017, n=1652, 70% females). MAIN OUTCOME MEASURES: The composite cardiometabolic risk score (CMRS) (scaled 0-8) was calculated using eight biomarkers (body mass index, waist circumference, blood glucose, systolic and diastolic blood pressure, total and high-density lipoprotein-cholesterol, triglycerides). Social characteristics included education in both countries, income in CZ and a composite measure of social position (SP) in VE. Sex stratified ordinal regression examined the social gradient in having less favourable CMRS. RESULTS: In CZ, men and women with low education and women with low income had higher odds of higher CMRS compared with those with high education and income with OR 1.45 (95% CI 1.01 to 2.21), 2.29 (95% CI 1.62 to 3.24) and 1.69 (95% CI 1.23 to 2.35). In VE, women with low education and low SP had higher odds to have higher CMRS OR 1.47 (95% CI 1.09 to 1.97) and 1.51 (95% CI 1.16 to 1.97), while men with low education and low SP had lower odds to have higher CMRS OR 0.64 (95% CI 0.41 to 1.00) and 0.61 (95% CI 0.40 to 0.97), compared with those with high education and high SP. Independently of age, sex and socioeconomic characteristics, Venezuelans had higher odds to have higher CMRS than Czechs (OR 2.70; 95% CI 2.37 to 3.08). CONCLUSIONS: The results suggest that the associations of socioeconomic status indices and cardiometabolic risk differed between CZ and VE, likely reflecting differences in the social environment among countries. Further research is needed to confirm and quantify these differences.

Transcranial Direct Current Stimulation Combined With or Without Caffeine: Effects on Training Volume and Pain Perception.

Purpose: This study aimed to investigate the acute effects of tDCS combined with caffeine intake on training volume and pain perception in the bench press in resistance-trained males. The correlation between training volume and pain perception was also assessed in all interventions. Methods: Sixteen healthy males (age = 25.2 ± 4.7 years, body mass = 82.8 ± 9.1 kg, and height = 178.3 ± 5.7 cm), advanced in RT, were randomized and counterbalanced for the following experimental conditions: Sham tDCS with placebo intake (Sham+Pla), Sham tDCS with caffeine intake (Sham+Caff), anodal tDCS with placebo intake (a-tDCS+Pla), and anodal tDCS with caffeine intake (a-tDCS+Caff). The caffeine or placebo ingestion (both with 5 mg.kg-1) occurred 40 minutes before the tDCS sessions. The tDCS was applied over the left DLPFC for 20 minutes, with a 2 mA current intensity. After the tDCS sessions, participants performed the bench press with an 80% of 1RM load, where training volume and pain perception were measured. Results: Training volume was higher in the 1st and 2nd sets in both a-tDCS+Caff and Sham+Caff conditions, compared to the Sham+Pla condition (P < .05). Both a-tDCS+Caff and a-tDCS+Pla showed an increased pain perception during the third set compared to the first set. Also, no correlation was found between the number of repetitions and pain perception in any condition (P > .05). Conclusion: This research revealed that caffeine intake alone could be used as an ergogenic aid during resistance training programs in resistance-trained males.

Association of Self-Reported Depression Symptoms with Physical Activity Levels in Czechia.

Worldwide, depressive disorder is one of the leading determinants of disability-adjusted life years. Although there are benefits associated with a higher physical activity (PA) level, there is a lack of information related to this relationship, especially in countries such as Czechia, where modern approaches to mental health care only recently emerged. The present study aimed to evaluate the association between the level of depression and different PA levels following the World Health Organization (WHO) PA guidelines and according to specific symptoms that indicate depression. Multivariable-adjusted Poisson regression models were used to calculate the prevalence rate (PR) in a sample of 2123 participants (45.3% men, median 48 years). Compared to subjects with insufficient PA, moderate and high PA levels were inversely associated with continuous depression scores (PR = 0.85; 95% CI: 0.75-0.97; and PR = 0.80; 95% CI: 0.70-0.92). Depressed mood and worthlessness were the symptoms associated with moderate and high PA. Tiredness, change in appetite, and concentration problems were related to high PA. The results suggest that reaching the minimum PA target according to the guidelines seems to be effective, and this could stimulate adherence. However, more specific improvements in symptomatology will require a subsequent gradual increase in PA levels.

Associations between Per- and Polyfluoroalkyl Substances (PFAS) and Cardiometabolic Biomarkers in Adults of Czechia: The Kardiovize Study.

Even though there is evidence of decreasing trends of per- and polyfluoroalkyl substances (PFAS) in Czechia, there are still major sources of PFAS pollution. Regarding the still-inconsistent results of the relationship between cardiometabolic health and PFAS, the present study sought to determine the association between PFAS levels and the presence of cardiometabolic biomarkers, including blood pressure and dysglycemia drivers in the Czech population. A cross-sectional study with 479 subjects (56.4% women, median: 53 years, range: 25-89) was conducted. Four PFAS were measured in serum: perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), and perfluorooctane sulfonate (PFOS). The associations between natural log (ln)-transformed PFAS and cardiometabolic biomarkers were assessed through generalized additive models using linear regression and smoothing thin plate splines, adjusted for potential confounders. There were positive and significant (p < 0.05) associations between the ln-transformed PFOA and glucose (ß = 0.01), systolic (ß = 0.76) and diastolic blood pressure (ß = 0.65); total cholesterol (ß = 0.07) and LDL-c (ß = 0.04); and PFOS with glucose (ß = 0.03), BMI (ß = 2.26), waist circumference (ß = 7.89), systolic blood pressure (ß = 1.18), total cholesterol (ß = 0.13), and HDL-c (ß = 0.04). When significant, the correlations of PFNA and PFDA were negative. Of the four PFAS, only PFOA and PFOS showed a positive association, even in serum levels not as high as the values from the literature.

Correction: Psychosocial and environmental determinants of physical activity in a Brazilian public university employees-ELDAF: A prospective cohort study protocol.

[This corrects the article DOI: 10.1371/journal.pone.0263385.].

Prevalência de dores nas costas em adultos praticantes de atividade física: estudo de base populacional / Prevalence of back pain in adults practicing physical activity: a population-based study

O presente estudo teve como objetivo identificar a prevalência de indivíduos que praticam atividade física com dores nas costas e a prevalência de dores nas costas em cada modalidade de atividade física praticada por adultos. Foram utilizadas as informações dos indivíduos selecionados para responder o questionário individual da Pesquisa Nacional de Saúde (PNS). A amostra do presente estudo foi composta 15043 indivíduos, com faixa de idade entre 18 e 59 anos de idade, praticantes de atividades físicas, que responderam todas as questões selecionadas. A análise estatística dos dados foi realizada de maneira descritiva, para análise da prevalência de indivíduos adultos ativos fisicamente com dores nas costas e, ainda, entre os praticantes de cada modalidade de atividade física relatada, com as respectivas frequências e intervalos de confiança. Nos resultados foram apresentados valores de 2055 (15,9%) indivíduos adultos praticantes de atividade física com dores nas costas. A prevalência em mulheres (19,6%) e em adultos de meia idade (24,2%) tende a ser maior que em homens (12,0%) e em adultos mais jovens (12,6%), respectivamente. A caminhada foi a atividade mais procurada e a prevalência de dores foi de 20,3%. Outras atividades que podem trazer benefícios às dores nas costas apresentaram prevalências consideradas altas, possivelmente por serem procuradas para fazerem parte do tratamento. Por modalidades específicas de atividade física, os valores de prevalência de dores nas costas são variados quando a população é dividida em grupos por sexo e idade. Entretanto, não é possível estabelecer uma relação de causalidade entre estas atividades físicas e a dor nas costas devido limitações dos dados coletados. Os valores das prevalências observados neste estudo devem ser considerados importantes para reflexões acerca de atividades físicas adequadas e à prescrição e controle de exercícios. (AU)

The present study aimed to identify the prevalence of individuals who practice physical activity with back pain and the prevalence of back pain in each type physical activity practiced by adults. Individuals selected to answer the individual questionnaire from the National Health Survey (PNS) were part of the study. The sample consisted of 15043 individuals, aged between 18 and 59 years old, who practice physical activities, who answered all selected questions. The statistical analysis of the data was performed descriptively for the prevalences, with frequencies and confidence intervals, of adult individuals physically active with back pain and, also, among the practitioners of each type of physical activity reported.The results showed values for 2055 (15.9%) adult individuals physically active with back pain. The prevalence in women (19.6%) and middle-aged adults (24.2%) tends to be higher than in men (12.0%) and in younger adults (12.6%), respectively. Walking was the most sought after activity and the prevalence among practitioners was 20.3%. Other activities that can bring benefits to back pain had prevalences considered high possibly because they were sought as part of the treatment. By specific modalities of physical activity, the prevalence values of back pain are varied when the population is divided into groups by sex and age. However, a causal relationship is not possible between these physical activities and back pain due to limitations of the data collected. The pr evalence values found should be considered of concern, mainly for the indication of adequate physical activity and the prescription and control of exercises. The prevalence values observed in this study should be considered important for reflections on adequate physical activities a nd the prescription and control of exercises. (AU)

Psychosocial and environmental determinants of physical activity in a Brazilian public university employees - ELDAF: A prospective cohort study protocol.

BACKGROUND: Increased physical activity levels and their determinations are essential issues worldwide. The Longitudinal Study of Physical Activity Determinants (ELDAF) aims to understand the roles of psychosocial and environmental factors in workers' physical activity levels. METHODS: A prospective cohort study of non-faculty civil servants from a public university (approximately 1,200 individuals) will start in 2022 (baseline). The primary measurements will be accelerometer- and questionnaire-based physical activity, social support, social network, socioeconomic status, bereavement, job stress, body image, common mental disorders, depression, and neighborhood satisfaction. Additional measurements will include necessary sociodemographic, physical morbidity, lifestyle and anthropometric information. Participants' places of residence will be geocoded using complete addresses. All participants will furnish written, informed consent before the beginning of the study. Pilot studies were performed to identify and correct potential problems in the data collection instruments and procedures. ELDAF will be the first cohort study conducted in Latin America to investigate physical activity and its determinants.

The Combined Effects of Television Viewing and Physical Activity on Cardiometabolic Risk Factors: The Kardiovize Study.

The aim of the present study was to evaluate the association between television viewing/physical activity (TVV/PA) interactions and cardiometabolic risk in an adult European population. A total of 2155 subjects (25-64 years) (45.2% males), a random population-based sample were evaluated in Brno, Czechia. TVV was classified as low (<2 h/day), moderate (2-4), and high (≥4). PA was classified as insufficient, moderate, and high. To assess the independent association of TVV/PA categories with cardiometabolic variables, multiple linear regression was used. After adjustments, significant associations were: High TVV/insufficient PA with body mass index (BMI) (ß = 2.61, SE = 0.63), waist circumference (WC) (ß = 7.52, SE = 1.58), body fat percent (%BF) (ß = 6.24, SE = 1.02), glucose (ß = 0.25, SE = 0.12), triglycerides (ß = 0.18, SE = 0.05), and high density lipoprotein (HDL-c) (ß = -0.10, SE = 0.04); high TVV/moderate PA with BMI (ß = 1.98, SE = 0.45), WC (ß = 5.43, SE = 1.12), %BF (ß = 5.15, SE = 0.72), triglycerides (ß = 0.08, SE = 0.04), total cholesterol (ß = 0.21, SE = 0.10), low density protein (LDL-c) (ß = 0.19, SE = 0.08), and HDL-c (ß = -0.07, SE = 0.03); and moderate TVV/insufficient PA with WC (ß = 2.68, SE = 1.25), %BF (ß = 3.80, SE = 0.81), LDL-c (ß = 0.18, SE = 0.09), and HDL-c (ß = -0.07, SE = 0.03). Independent of PA levels, a higher TVV was associated with higher amounts of adipose tissue. Higher blood glucose and triglycerides were present in subjects with high TVV and insufficient PA, but not in those with high PA alone. These results affirm the independent cardiometabolic risk of sedentary routines even in subjects with high-levels of PA.

Effects of Anodal Transcranial Direct Current Stimulation on Training Volume and Pleasure Responses in the Back Squat Exercise Following a Bench Press.

ABSTRACT: Rodrigues, GM, Machado, S, Faria Vieira, LA, Ramalho de Oliveira, BR, Jesus Abreu, MA, Marquez, G, Maranhão Neto, GA, and Lattari, E. Effects of anodal transcranial direct current stimulation on training volume and pleasure responses in the back squat exercise following a bench press. J Strength Cond Res 36(11): 3048-3055, 2022-This study aimed to investigate the effects of anodal transcranial direct current stimulation (a-tDCS) on volume-load and pleasure responses in a back squat following a bench press. Twelve male subjects advanced in resistance training (RT) (age, 25.5 ± 4.4 years) completed 2 experimental trials in a counterbalanced crossover design: a-tDCS and sham conditions. The stimulus was applied over the left dorsolateral prefrontal cortex for 20 minutes using a 2-mA current intensity in a-tDCS condition and 1 minute of active stimulus in the sham condition. Immediately after stimulation, subjects performed the bench press followed by the back squat. The exercise protocol consisted of 3 sets of maximum repetitions at an intensity of 80% of 1 repetition maximum. The volume-load, perceived pleasure, and arousal responses were measured during the RT protocol. The results indicated that volume-load was higher in the a-tDCS condition than in the sham condition for both exercises ( p = 0.02), with large effect for the back squat ( p = 0.045; d = 0.96). The higher volume-load was obtained by increasing the number of repetitions across all sets for the bench press ( p ≤ 0.0001) and only in the first set for the back squat ( p = 0.01). The circumplex model analysis showed a higher pleasure in the bench press and a tendency toward a higher pleasure in the a-tDCS condition. Anodal tDCS may be used as an ergogenic resource for increasing the back squat volume after performing the bench press in resistance-trained male subjects.

Association between social support and frequency of physical activity in adult workers.

Introduction: The benefits of taking up physical activity are well established and social support has been identified as one of the main determinants of this behavior. Objectives: To investigate the association between social support and weekly frequency of physical activity in adults working at a public university in the state of Rio de Janeiro, Brazil. Methods: This is a cross-sectional population study with a convenience sample of 189 contract workers of both sexes, aged from 21 to 72 years (39.00 ± 11.43). The instruments employed were the short version of the International Physical Activity Questionnaire and the Social Support for Physical Activities Scale. Fisher's exact test was used to estimate the distribution of physical activity frequency. Poisson regression was used for association analyses. The significance level was set at 5%. Results: A significant association was detected between social support and weekly physical activity frequency (p < 0.05). Social support for physical activity of moderate or vigorous intensity was associated with both weekly frequency of walking (odds ratio [OR]: 1.32; 95% confidence interval [95%CI]: 1.11-1.58) and weekly frequency of vigorous physical activity (OR: 1.34; 95%CI: 1.08-1.67). Additionally, people who reported receiving social support for walking were more likely to have increased weekly frequency of walking (OR: 1.22; 95%CI: 1.00-1.49). Conclusions: Social support for physical activity from relatives and friends is associated with weekly physical activity frequency. Notwithstanding, this association was stronger for weekly frequency of vigorous intensity physical activity.

Introdução: Os benefícios advindos da adoção da atividade física estão bem consolidados, e o apoio social tem sido apontado como um dos principais determinantes desse comportamento. Objetivos: Investigar a associação entre apoio social e frequência semanal de atividade física em adultos trabalhadores de uma universidade pública do estado do Rio de Janeiro. Métodos: Tratou-se de um estudo transversal de base populacional, abarcando uma amostra de conveniência de 189 funcionários terceirizados de ambos os sexos, com idades entre 21 e 72 anos (39,00 ± 11,43). A versão curta do Questionário Internacional de Atividade Física e a Escala de Apoio Social para Atividades Físicas foram os instrumentos utilizados. Para estimar a distribuição da frequência em atividades físicas, foi aplicado o teste exato de Fisher. A regressão de Poisson foi utilizada para análise de associação. O nível de significância adotado foi de 5%. Resultados: Uma diferença significante foi encontrada entre apoio social e frequência semanal de atividade física (p < 0,05). O apoio social para atividade física de intensidade moderada ou vigorosa esteve associado tanto com frequência semanal de caminhada (razão de chances [OR, de odds ratio]: 1,32; intervalo de confiança de 95% [IC95%]: 1,11-1,58) quanto com frequência de atividade física vigorosa (OR: 1,34; IC95%: 1,08-1,67). Além disso, indivíduos que reportaram receber apoio social para caminhada tiveram mais chances de aumentar a frequência semanal de caminhada (OR: 1,22; IC95%: 1,00-1,49). Conclusões: O apoio social para atividade física advindo de familiares e amigos está associado à frequência semanal de atividade física. Contudo, a associação se mostrou mais evidente para frequência semanal de atividade física de intensidade vigorosa.

Transcranial Direct Current Stimulation (tDCS) Improves Back-Squat Performance in Intermediate Resistance-Training Men.

Purpose: The purpose of this study was to evaluate the effects of anodal tDCS applied over the dorsolateral prefrontal cortex (DLPFC) on muscle endurance in the back-squat exercise. Methods: Eleven healthy males, intermediate in resistance training (RT), aged between 18 and 31 years (25.5 ± 4.4 years) were recruited. In the initial visits (1st and 2nd visits), participants performed a 1RM test to determine the load in the back-squat exercise. Following the two initials visits, participants attended the lab for the two experimental conditions (anodal tDCS and sham), which were completed a week apart, with sessions randomly counterbalanced. The stimulation was applied over the DLPFC for 20 minutes using a 2 mA current intensity. Immediately after the experimental conditions, participants completed three sets of maximum repetitions (80% of 1RM), with a 1-minute recovery interval between each set in the back-squat exercise. Muscle endurance was determined by the total number of repetitions and the number of repetitions in each set. Results: The total number of repetitions was higher in the anodal tDCS condition compared to sham condition (p ≤ .0001). Moreover, the number of repetitions performed in the first set was higher for anodal tDCS condition than in the sham condition (p ≤ .01). Conclusion: This study found improvement in back-squat exercise performance after the application of anodal tDCS. The effects of anodal tDCS applied over DLPFC may be a promising ergogenic resource on muscle endurance in the back-squat exercise.

Anodal Transcranial Direct Current Stimulation Increases Muscular Strength and Reduces Pain Perception in Women With Patellofemoral Pain.

ABSTRACT: Rodrigues, GM, Paixão, A, Arruda, T, de Oliveira, BRR, Maranhão Neto, GA, Marques Neto, SR, Lattari, E, and Machado, S. Anodal transcranial direct current stimulation increases muscular strength and reduces pain perception in women with patellofemoral pain. J Strength Cond Res 36(2): 371-378, 2022-The purpose of this study is to investigate the effects of anodic transcranial direct current stimulation applied to motor cortex combined with open kinetic chain exercises on muscular strength and pain perception in women with patellofemoral pain (PFP). Twenty-eight women aged between 18 and 30 years with PFP were selected. Subjects were randomized in 2 groups, anodic stimulus plus resistance training (n = 14; anodic transcranial direct current stimulation [a-tDCS] + RT) or placebo stimulus plus resistance training (n = 14; Sham + RT) and attended the laboratory for 12 experimental sessions, 48-72 hours apart from each other. The RT protocol consisted of 3 sets of 12 repetitions of the knee extension exercise at 60% of 10 maximal repetition (10RM) with a 1-minute interval between sets. In the a-tDCS + RT group, a 2-mA current was applied for 20 minutes over the motor cortex before the RT protocol in each session. In the Sham + RT group, the stimulus was interrupted after 30 seconds. Preintervention, fourth session, eighth session, and postintervention, load was assessed through a 10RM test. The pain perception was assessed through Clarke sign maneuver (CSM) and measured through a visual analogue scale for pain. The a-tDCS + RT group showed greater 10RM load than Sham + RT group at eighth session (p < 0.05) and postintervention (p < 0.05). In a-tDCS + RT group, pain perception reduced in the postintervention compared with preintervention (p < 0.05). The intervention a-tDCS + RT was able to improve muscular strength in women with PFP. In addition, pain perception only decreased postintervention in the a-tDCS + RT group. This combined intervention can be used by coaches in rehabilitation programs aiming to treat PFP through medium-term strength gains.

Prevalence of adiposity-based chronic disease in middle-aged adults from Czech Republic: The Kardiovize study.

AIMS/HYPOTHESIS: The need for understanding obesity as a chronic disease, its stigmatization, and the lack of actionability related to it demands a new approach. The adiposity-based chronic disease (ABCD) model is based on adiposity amount, distribution, and function, with a three stage complication-centric rather than a body mass index (BMI)-centric approach. The prevalence rates and associated risk factors are presented. METHODS: In total, 2159 participants were randomly selected from Czechia. ABCD was established as BMI ≥ 25 kg/m2 or high body fat percent, or abdominal obesity and then categorized by their adiposity-based complications: Stage 0: none; Stage 1: mild/moderate; Stage 2: severe. RESULTS: ABCD prevalence was 62.8%. Stage 0 was 2.3%; Stage 1 was 31.4%; Stage 2 was 29.1%. Comparing with other classifiers, participants in Stage 2 were more likely to have diabetes, hypertension, and metabolic syndrome than those with overweight, obesity, abdominal obesity, and increased fat mass. ABCD showed the highest sensitivity and specificity to detect participants with peripheral artery disease, increased intima media, and vascular disease. CONCLUSION/INTERPRETATION: The ABCD model provides a more sensitive approach that facilitates the early detection and stratification of participants at risk compared to traditional classifiers.

Prediction of Cardiorespiratory Fitness in Czech Adults: Normative Values and Association with Cardiometabolic Health.

Cardiorespiratory fitness (CRF) is a strong independent predictor of morbidity and mortality. However, there is no recent information about the impact of CRF on cardiometabolic risk specifically in Central and Eastern Europe, which are characterized by different biological and social determinants of health. In this cross-sectional study normative CRF values were proposed and the association between CRF and cardiometabolic outcomes was evaluated in an adult Czechian population. In 2054 participants (54.6% females), median age 48 (IQR 19 years), the CRF was predicted from a non-exercise equation. Multivariable-adjusted logistic regressions were carried out to determine the associations. Higher CRF quartiles were associated with lower prevalence of hypertension, type 2 diabetes (T2D) and dyslipidemia. Comparing subjects within the lowest CRF, we see that those within the highest CRF had decreased chances of hypertension (odds ratio (OR) = 0.36; 95% CI: 0.22-0.60); T2D (OR = 0.16; 0.05-0.47), low HDL-c (OR = 0.32; 0.17-0.60), high low-density lipoprotein (OR = 0.33; 0.21-0.53), high triglycerides (OR = 0.13; 0.07-0.81), and high cholesterol (OR = 0.44; 0.29-0.69). There was an inverse association between CRF and cardiometabolic outcomes, supporting the adoption of a non-exercise method to estimate CRF of the Czech population. Therefore, more accurate cardiometabolic studies can be performed incorporating the valuable CRF metric.

Dysglycemia and Abnormal Adiposity Drivers of Cardiometabolic-Based Chronic Disease in the Czech Population: Biological, Behavioral, and Cultural/Social Determinants of Health.

In contrast to the decreasing burden related to cardiovascular disease (CVD), the burden related to dysglycemia and adiposity complications is increasing in Czechia, and local drivers must be identified. A comprehensive literature review was performed to evaluate biological, behavioral, and environmental drivers of dysglycemia and abnormal adiposity in Czechia. Additionally, the structure of the Czech healthcare system was described. The prevalence of obesity in men and diabetes in both sexes has been increasing over the past 30 years. Possible reasons include the Eastern European eating pattern, high prevalence of physical inactivity and health illiteracy, education, and income-related health inequalities. Despite the advanced healthcare system based on the compulsory insurance model with free-for-service healthcare and a wide range of health-promoting initiatives, more effective strategies to tackle the adiposity/dysglycemia are needed. In conclusion, the disease burden related to dysglycemia and adiposity in Czechia remains high but is not translated into greater CVD. This discordant relationship likely depends more on other factors, such as improvements in dyslipidemia and hypertension control. A reconceptualization of abnormal adiposity and dysglycemia into a more actionable cardiometabolic-based chronic disease model is needed to improve the approach to these conditions. This review can serve as a platform to investigate causal mechanisms and secure effective management of cardiometabolic-based chronic disease.

Visceral fat area and cardiometabolic risk: The Kardiovize study.

BACKGROUND: Visceral fat is associated with adiposity-based complications. Bioimpedance measurement allows estimation of visceral fat area (VFA) in an easy manner. However, a validated cut-off value for VFA by bioimpedance associated with cardiometabolic risk is lacking in European population. AIM: To determine cut-off values of VFA measured via bioimpedance associated with cardiometabolic risk. METHODS: Random cross-sectional Czech population-based sample of 25-64 years old subjects. Receiver Operating Characteristic (ROC) curves were used and the area under the curve (AUC), sensitivity, and specificity were calculated. The Cardiometabolic Disease Staging System (CMDS) was used to classify cardiometabolic risk: Stage 1 - 1 or 2 metabolic syndrome (MetS) components, without impaired fasting glucose (IFG); Stage 2 - MetS or IFG; Stage 3 - MetS with IFG; Stage 4 - type 2 diabetes and/or cardiovascular disease. RESULTS: 2052 participants (54.5% females, median age 49 years) were included. Median VFA (inter-quartile range) were 82.2 cm2 (54.8) in men and 89.8 cm2 (55.6) in women. The best VFA cut-offs associated with Stage 1 in men and women were 71 cm2 (sensitivity = 0.654; specificity = 0.427) and 83 cm2 (sensitivity = 0.705; specificity = 0.556) ; Stage 2: 84 cm2 (sensitivity = 0.673; specificity = 0.551) and 98 cm2 (sensitivity = 0.702; specificity = 0.628) ; Stage 3: 90 cm2 (sensitivity = 0.886; specificity = 0.605) and 109 cm2 (sensitivity = 0.755; specificity = 0.704); Stage 4: 91 cm2 (sensitivity = 0.625; specificity = 0.611) and 81 cm2 (sensitivity = 0.695; specificity = 0.448), respectively. CONCLUSION: A cut-off value of VFA of 71 cm2 in men and 83 cm2 in women exhibited the earliest stage of cardiometabolic risk, and 90 cm2 in men and 109 cm2 in women showed the best performance to detect risk.

Psychosocial determinants of physical activity among workers: an integrative review.

Knowledge of the psychosocial determinants of physical activity is critical to informing preventive and therapeutic interventions in the workplace. This study reviewed available evidence on psychosocial factors that have been associated with physical activity among workers. Studies were selected in December 2019 from the Scopus, Web of Science, and PubMed databases, with no date limits, using the following search terms: "physical activity", "physical exercise", "psychosocial", "workers", and "working-age". Thirty-nine studies published between 1991 and 2019 were evaluated. The determinants of physical activity investigated among workers were smoking status, stress, psychosocial working conditions, depression, anxiety, social relationships, work ability, job satisfaction, burnout, and self-efficacy. Some consistencies and controversies were observed in the associations among these determinants and physical activity and are discussed, as are suggestions for future studies. The findings of this review may be of interest to physical activity interventions designed to reduce psychosocial risks factors in work environments.