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Nutrients ; 11(12)2019 Dec 10.
Artigo em Inglês | MEDLINE | ID: mdl-31835476

RESUMO

Background: Consumption of fibre-enriched orange juice may be an appropriate way to supplement daily fibre intake and achieve beneficial effects on metabolic health. The present study aimed to assess the short-term effects of fibre-enriched orange juice on postprandial metabolism and satiety in a healthy adult population. Methods: In this double-blind, randomised, placebo-controlled, crossover study 10 healthy subjects underwent two one-day trials in which they consumed an orange juice beverage containing 1.4 g/100 mL of citrus fibre (29.3% soluble and 41.9% insoluble) or a placebo (regular orange juice without added fibre). Postprandial glucose, insulin, gut hormones (GLP1, GIP and ghrelin), leptin and qualitative appetite/satiety assessment were measured every 15 or 30 min over the 120 min test period. Results: The fibre-enriched orange juice decreased postprandial serum glucose and circulating insulin levels at 15 min compared with the placebo. In addition, after intake of the fibre-enriched juice, a significant effect on qualitative feelings of satiety and fullness was observed at 15 and 120 min, and was accompanied by a significant decrease in GLP1 response at 15 min. No significant changes were observed in leptin, GIP and ghrelin after juice intake. Conclusions: In healthy individuals, a single acute consumption of fibre-enriched orange juice has short-term beneficial effects on postprandial glycaemia, circulating insulin levels and satiety through GLP1 secretion.


Assuntos
Citrus sinensis/química , Fibras na Dieta/administração & dosagem , Sucos de Frutas e Vegetais , Índice Glicêmico/efeitos dos fármacos , Período Pós-Prandial/efeitos dos fármacos , Saciação/efeitos dos fármacos , Adulto , Apetite/efeitos dos fármacos , Glicemia/análise , Glicemia/metabolismo , Estudos Cross-Over , Método Duplo-Cego , Feminino , Grelina/sangue , Peptídeo 1 Semelhante ao Glucagon/sangue , Voluntários Saudáveis , Humanos , Insulina/sangue , Masculino , Fatores de Tempo , Adulto Jovem
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