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1.
Sensors (Basel) ; 23(21)2023 Nov 04.
Artigo em Inglês | MEDLINE | ID: mdl-37960673

RESUMO

As was shown in the previous part of the study, windshields are an important part of the passive safety means of modern low-floor trams with an extraordinary effect on pedestrian safety in a pedestrian-tram collisions. Therefore, maximum attention must be paid to the definition of tram windshield characteristics. This article describes a windshield crash test, from which data are obtained to verify the feasibility of the applied computational approaches. A developed analytical model is utilised for a simple description of the energy balance during collision with an illustrative definition of the important parameters of laminated glass as well as their clear physical interpretations. The finite element analysis (FEA) performed in Ansys software using two versions of material definition, namely a simpler (*MAT_ELASTIC with nonlocal failure criterion) and a more complex (*MAT_GLASS with brittle stress-state-dependent failure) material model, which are presented as suitable for obtaining a detailed description of the shattering process of laminated glass, which can also be used effectively in windshield engineering.

2.
Sensors (Basel) ; 23(21)2023 Oct 30.
Artigo em Inglês | MEDLINE | ID: mdl-37960520

RESUMO

This article represents the first paper in a two-part series dealing with safety during tram-pedestrian collisions. This research is dedicated to the safety of trams for pedestrians during collisions and is motivated by the increased number of lethal cases. The first part of this paper includes an overview of tram face development from the earliest designs to the current ones in use and, at the same time, provides a synopsis and explanation of the technical context, including a link to current and forthcoming legislation. The historical design development can be characterised by three steps, from an almost vertical front face, to leaned and pointed shapes, to the current inclined low-edged windshield without a protruding coupler. However, since most major manufacturers now export their products worldwide and customisation is only of a technically insignificant nature, our conclusions are generalisable (supported by the example of Berlin). The most advantageous shape of the tram's front, minimising the effects on pedestrians in all collision phases, has evolved rather spontaneously and was unprompted, and it is now being built into the European Commission regulations. The goal of the second part of this paper is to conduct a series of tram-pedestrian collisions with a focus on the frontal and side impacts using a crash test dummy (anthropomorphic test device-ATD). Four tram types approaching the collision at four different impact speeds (5 km/h, 10 km/h, 15 km/h, and 20 km/h) were used. The primary outcome variable was the resultant head acceleration. The risk and severity of possible head injuries were assessed using the head injury criterion (HIC15) and its linkage to the injury level on the Abbreviated Injury Scale (AIS). The results showed increasing head impacts with an increasing speed for all tram types and collision scenarios. Higher values of head acceleration were reached during the frontal impact (17-124 g) compared to the side one (2-84 g). The HIC15 values did not exceed the value of 300 for any experimental setting, and the probability of AIS4+ injuries did not exceed 10%. The outcomes of tram-pedestrian collisions can be influenced by the ATD's position and orientation, the impact speed and front-end design of trams, and the site of initial contact.


Assuntos
Traumatismos Craniocerebrais , Pedestres , Ferimentos e Lesões , Humanos , Acidentes de Trânsito , Veículos Automotores , Caminhada
3.
Neuro Endocrinol Lett ; 37(4): 301-307, 2016 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-27857047

RESUMO

OBJECTIVE: The human motion system reacts to both hypo and hyperactivity loads by changes to the rheological properties of tissues. This study deals with changes to the axial system (AS) compartment. Using the appropriate methodologies and mathematical-physical methods, these changes can be identified and quantified. METHODS: This study describes the noninvasive TVS (Transfer Vibration through Spine) method, which was applied to assess the AS selected mechanical properties in various modes. A pilot study was conducted on a top-level twelve-year-old girl-gymnast. The data detection was carried out in three cycles, before and after a peak 3.5 hour training session and the next day, after resting, just before the next training. RESULTS: Specifically, the values of selected rheological parameters, the AS damping coefficient b and viscosity µ, were obtained. The dynamics of their changes, in the stated load cycles, has also been shown. The damping coefficient b fell from the value of 0.626 to 0.324 before training and increased to 0.394 after resting. The viscosity coefficient µ showed a similar trend, namely falling from the value of 9.85 [Pa.s] to 2.15 [Pa.s] and then increasing to 3.8 [Pa.s] . CONCLUSIONS: With its computational solution, the TVS method,is a diagnostic apparatus making it possible to classify AS properties, both quantitatively and qualitatively, or its chosen segments and their changes, respectively. It can be used in classifying, preventing and treating the consequences of extreme motion and relaxing modes. The TVS application also makes it possible to control AS states over therapeutic, recovery, ergonomic and other loading modes of the human locomotion system.


Assuntos
Ginástica , Reologia , Coluna Vertebral/fisiologia , Vibração , Suporte de Carga/fisiologia , Fenômenos Biomecânicos , Criança , Feminino , Humanos , Projetos Piloto , Viscosidade
4.
Artigo em Inglês | MEDLINE | ID: mdl-26296149

RESUMO

Correctly dosed physical activity is the basis of a vital and healthy life, but the measurement of physical activity is certainly rather empirical resulting in limited individual and custom activity recommendations. Certainly, very accurate three-dimensional models of the cardiovascular system exist, however, requiring the numeric solution of the Navier-Stokes equations of the flow in blood vessels. These models are suitable for the research of cardiac diseases, but computationally very expensive. Direct measurements are expensive and often not applicable outside laboratories. This paper offers a new approach to assess physical activity using thermodynamical systems and its leading quantity of entropy production which is a compromise between computation time and precise prediction of pressure, volume, and flow variables in blood vessels. Based on a simplified (one-dimensional) model of the cardiovascular system of the human body, we develop and evaluate a setup calculating entropy production of the heart to determine the intensity of human physical activity in a more precise way than previous parameters, e.g. frequently used energy considerations. The knowledge resulting from the precise real-time physical activity provides the basis for an intelligent human-technology interaction allowing to steadily adjust the degree of physical activity according to the actual individual performance level and thus to improve training and activity recommendations.


Assuntos
Entropia , Exercício Físico/fisiologia , Corpo Humano , Ergometria , Frequência Cardíaca/fisiologia , Humanos , Masculino , Pessoa de Meia-Idade
5.
J Math Biol ; 69(6-7): 1383-429, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24212399

RESUMO

Bone remodelling is a fundamental biological process that controls bone microrepair, adaptation to environmental loads and calcium regulation among other important processes. It is not surprising that bone remodelling has been subject of intensive both experimental and theoretical research. In particular, many mathematical models have been developed in the last decades focusing in particular aspects of this complicated phenomenon where mechanics, biochemistry and cell processes strongly interact. In this paper, we present a new model that combines most of these essential aspects in bone remodelling with especial focus on the effect of the mechanical environment into the biochemical control of bone adaptation mainly associated to the well known RANKL-RANK-OPG pathway. The predicted results show a good correspondence with experimental and clinical findings. For example, our results indicate that trabecular bone is more severely affected both in disuse and disease than cortical bone what has been observed in osteoporotic bones. In future, the methodology proposed would help to new therapeutic strategies following the evolution of bone tissue distribution in osteoporotic patients.


Assuntos
Adaptação Fisiológica/fisiologia , Remodelação Óssea/fisiologia , Modelos Biológicos , Osteoporose/fisiopatologia , Fenômenos Biomecânicos/fisiologia , Simulação por Computador , Humanos , Osteoprotegerina/fisiologia , Ligante RANK/fisiologia , Receptor Ativador de Fator Nuclear kappa-B/fisiologia
6.
J Biomed Mater Res A ; 95(1): 9-24, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20540092

RESUMO

The aim of this article was to present a new thermodynamic-based model for bone remodeling which is able to predict the functional adaptation of bone in response to changes in both mechanical and biochemical environments. The model was based on chemical kinetics and irreversible thermodynamic principles, in which bone is considered as a self-organizing system that exchanges matter, energy and entropy with its surroundings. The governing equations of the mathematical model have been numerically solved using Matlab software and implemented in ANSYS software using the Finite Element Method. With the aid of this model, the whole inner structure of bone was elucidated. The current model suggested that bone remodeling was a dynamic process which was driven by mechanical loading, metabolic factors and other external contributions. The model clearly indicated that in the absence of mechanical stimulus, the bone was not completely resorbed and reaches a new steady state after about 50% of bone loss. This finding agreed with previous clinical studies. Furthermore, results of virtual computations of bone density in a composite femur showed the development of a dense cortical bone around the medullary canal and a dense trabeculae bone between the femoral head and the calcar region of the medial cortex due to compressive stresses. The comparison of the predicted bone density with the structure of the proximal femur obtained from X-rays and using strain energy density gave credibility to the current model.


Assuntos
Remodelação Óssea/fisiologia , Modelos Biológicos , Animais , Densidade Óssea/fisiologia , Simulação por Computador , Módulo de Elasticidade/fisiologia , Fêmur/diagnóstico por imagem , Fêmur/fisiologia , Humanos , Fenômenos Mecânicos , Osteoblastos/metabolismo , Reprodutibilidade dos Testes , Termodinâmica , Tomografia Computadorizada por Raios X , Suporte de Carga/fisiologia
7.
J Phys Chem B ; 113(44): 14689-97, 2009 Nov 05.
Artigo em Inglês | MEDLINE | ID: mdl-19863139

RESUMO

This paper offers a theoretical explanation of the coupling effect phenomenon between mechanical loading and chemical reactions based on linear nonequilibrium thermodynamics and also discusses the classical method of obtaining restrictions on the phenomenological coefficients. The question whether static or dynamic loading influences biochemical processes is addressed-the necessity of dynamic loading as a stimulatory mechanism is shown. Further, the presented paper suggests that chemical and mechanical processes do not only facilitate or support one another but they may also play a triggering role for the other coupled process-some biochemical processes may need mechanical stimulation to run and vice versa as well-chemical reactions may provide energy for some mechanical processes. As an example, a detailed analysis of a model for controlled autocatalytic reproduction is presented, where the coupling effect, i.e. the influence of dynamic loading on reaction kinetics, is demonstrated.

8.
Cardiovasc Eng ; 7(4): 156-61, 2007 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-18080208

RESUMO

This research is aimed to the determination of the changes in the cardiac energetic output for three different modes of cardiac rhythm pacing. The clinical investigation of thirteen patients with the permanent dual-chamber pacemaker implantation was carried out. The patients were taken to echocardiography examination conducted by way of three pacing modes (AAI, VVI and DDD). The myocardial energetic parameters-the stroke work index (SWI) and the myocardial oxygen consumption (MVO2) are not directly measurable, however, their values can be determined using the numerical model of the human cardiovascular system. The 24-segment hemodynamical model (pulsating type) of the human cardiovascular system was used for the numerical simulation of the changes of myocardial workload for cardiac rhythm pacing. The model was fitted by well-measurable parameters for each patient. The calculated parameters were compared using the two-tailed Student's test. The differences of SWI and MVO2 between the modes AAI and VVI and the modes DDD and VVI are statistically significant (P<0.05). On the other hand, the hemodynamic effects for the stimulation modes DDD and AAI are almost identical, i.e. the differences are statistically insignificant (P>0.05).


Assuntos
Estimulação Cardíaca Artificial/métodos , Contração Miocárdica/fisiologia , Humanos , Modelos Cardiovasculares , Miocárdio/metabolismo , Consumo de Oxigênio
9.
J Chem Phys ; 124(4): 044509, 2006 Jan 28.
Artigo em Inglês | MEDLINE | ID: mdl-16460187

RESUMO

Nucleation processes in the binary water-sodium chloride system are investigated in the sense of the classical nucleation theory (CNT). The CNT is modified to be able to handle the electrolytic nature of the system and is employed to investigate the acceleration of the nucleation process due to the presence of sodium chloride in the steam. This phenomenon, frequently observed in the Wilson zone of steam turbines, is called early condensation. Therefore, the nucleation rates of the water-sodium chloride mixture are of key importance in the power cycle industry.

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