[The syndrome of psycho-sensory-anatomical-functional auto-desadaptation in patients with malignant tumors of the maxillofacial region]. / Sindrom psikho-sensorno-anatomo-funktsional'noi autodezadaptatsii u bol'nykh so zlokachestvennymi opukholyami chelyustno-litsevoi oblasti.

OBJECTIVE: The aim of the study is to evaluate the syndrome of PSAF-autoadaptation in patients with tumors of maxillofacial localization based on the analysis of the results of a survey of the patient's Voluntary Confidential Information Sheet (DDIV Sheet). MATERIAL AND METHODS: The object of the study was 110 patients (39 men and 71 women (average age 58 years) with malignant neoplasms of the skin, tongue, bottom of the oral cavity, parotid salivary gland, upper jaw, submandibular salivary gland (stage II-IV of the disease). Rapid diagnostics of psycho-sensory-anatomical-functional-autoadaptation (PSAF) was performed by analyzing self-filled patient lists of DDIV with its self-assessment of the main complaints. After distributing complaints and manifestations of the disease into 4 clusters, the severity and structure of autoadaptation were calculated in points. RESULTS: It was found that in the majority of cancer patients in the preoperative period, complaints related to mental and functional clusters prevailed. At the same time, 80% of patients rated the degree of concern for their health as extremely alarming, and 20% as very anxious. In the postoperative period, the number of psychological complaints decreased and the number of complaints corresponding to anatomical, sensory and functional clusters increased. CONCLUSION: The study of personal response to the disease according to PSAF-autoadaptation of cancer patients showed that the presence of a tumor lesion not only affects the internal picture of the disease, adversely affects the physical, mental and social well-being of patients, but also requires the involvement of psychologists, psychotherapists, clinical pharmacologists in the treatment of cognitive behavioral psychotherapy.

[Kimura's disease. (Clinical case study)]. / Bolezn' Kimury. (Sobstvennoe nablyudenie).

The author presents his own observation of a patient with Kimura's disease (CD), which is a rather rare chronic inflammatory disease of soft tissues. The results of clinical examination and surgical treatment of this disease are presented. It is emphasized that for the diagnosis of CD, first of all, an excision biopsy of the lesion is necessary, as well as the presence of eosinophilia in the patient, an increased level of immunoglobulin E (IgE) in peripheral blood, an increase in regional lymph nodes.

[A comparative evaluation of the immune status of patients with squamous-cell cancer of the oral mucosa at different stages of combined treatment]. / Sravnitel'naia otsenka immunnogo statusa bol'nykh ploskokletochnym rakom slizistoi obolochki organov polosti rta na razlichnykh étapakh kombinirovannogo lecheniia.

Shifts in immunity values were detected in 160 patients with oral cancer before specific therapy and at all stages of multiple-modality treatment. High diagnostic significance of measuring concentrations of circulating immune complexes in the serum for prediction of tumor relapse or metastases is demonstrated.