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1.
Trop Biomed ; 29(4): 580-7, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23202603

RESUMO

Snake bite has been regarded as an important health problem in Myanmar since early 1960's. In the recent years, there has been growing interest in alternative therapies and therapeutic use of natural products, especially those derive from plants. In Myanmar and Indian traditional medicine, various plants have used as a remedy for treating snake bite. The present study was carried out to evaluate the effects of alcohol extract of Tamarind (Tamarindus indica Linn.) seed on some biologic properties of Russell's viper (Daboia russelli siamensis) venom (RVV). The Phospholipase A2 (PLA2) enzyme, coagulase enzyme and caseinolytic enzyme activities of Russell's viper venom (RVV) were reduced when mixed and incubated with the extract. When the RVV and the different amount of extracts were preincubated and injected intramuscularly into mice, all of them survived, but all the mice in the control group died. On the other hand, when RVV were injected first followed by the extract into mice, all of them died. If the extract was injected near the site where Russell's viper venom was injected, all the mice survived for more than 24 hours and the survival time prolonged but they all died within 96 hours. In conclusion, according to the results obtained, the extract neutralizes some biologic properties of the Russell's viper venom and prolonged the survival time if the extract was injected near the site where the Russell's viper venom was injected.


Assuntos
Antídotos/farmacologia , Daboia , Tamarindus/química , Peçonhas/toxicidade , Animais , Antídotos/isolamento & purificação , Antídotos/uso terapêutico , Coagulase/antagonistas & inibidores , Feminino , Humanos , Masculino , Metaloendopeptidases/antagonistas & inibidores , Camundongos , Mianmar , Inibidores de Fosfolipase A2 , Sementes/química , Análise de Sobrevida , Resultado do Tratamento , Peçonhas/enzimologia
2.
Phys Rev C Nucl Phys ; 34(6): 2377-9, 1986 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-9953732

RESUMO

We calculate total cross sections for coherent pion production using localized plane-wave approximations for the shell-structure of valence nucleons that are excited to delta particles in the intermediate state in the (12C, 12B) and (12C, 12N) charge-exchange, heavy-ion reactions. We find comparable agreement to projectile downshift data for 12C(12C, 12B)12N. Then we improve the formalism by replacing the localized plane wave bound states with harmonic oscillator states which are imbedded in a multipole expansion approach and calculate pion differential cross sections to test for the sensitivity of the spectra to the single-particle mass parameter.


Assuntos
Partículas Elementares , Íons , Modelos Moleculares , Boro , Carbono , Nitrogênio , Análise Espectral
3.
Phys Rev C Nucl Phys ; 33(1): 396-8, 1986 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-9953160

RESUMO

We calculate the coherent production of pions from subthreshold to relativistic energies in heavy-ion collisions using a quantum, microscopic, many-body model. For the first time, in this approach, we use harmonic oscillator wave functions to describe shell-model information. The theoretical quantum mechanical results obtained for the pion spectra represent an important improvement over our previous microscopic, many-body calculations.


Assuntos
Mésons , Modelos Teóricos , Teoria Quântica , Radiação Cósmica
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