[Atherosclerosis of abdominal aorta and carotid arteries and its correlation with blood serum lipid levels in cholelithiasis]. / Ateroskleroz briushnoi aorty i sonnykh arterii i ego korreliatsiia s soderzhaniem lipidov v syvorotke krovi pri zhelchnokamennoi bolezni.

AIM: To elucidate relationship between cholelithiasis and presence and severity of atherosclerosis in abdominal aorta and carotid arteries. MATERIAL AND METHODS: Ultrasound investigation of vessels and abdominal organs, determination of blood serum total, high density lipoprotein cholesterol and triglycerides were carried out in 147 patients with and 167 without (controls) cholelithiasis (mean age 44.2+/-3.1 and 45+/-2.8 years, respectively). RESULTS: Among patients with cholelithiasis 73.2 and 67.6% had atherosclerosis of abdominal aorta and carotid arteries, respectively. This was significantly more than in controls. Compared with controls atherosclerosis of these vessels in all age groups was significantly more pronounced in patients with cholelithiasis. Moreover severity of atherosclerosis was directly related to duration and activity of cholelithiasis. Atherosclerosis of abdominal aorta and carotids was most pronounced in patients with cholelithiasis and concomitant hypertension, ischemic heart disease and obesity. Significant direct correlations were found between blood serum levels of total cholesterol, triglycerides and low density lipoprotein cholesterol and thickness of abdominal aortic wall and carotid artery intima media complex. CONCLUSION: The results evidence for the existence of association between cholelithiasis and presence and severity of atherosclerosis of abdominal aorta and carotid arteries.

[Dobutrex stress echocardiography: clinical and prognostic value, side effects]. / Nagruzochnaia ékhokardiografiia s dobutreksom: klinicheskoe i prognosticheskoe znachenie, pobochnye effekty.

AIM: To study informative value of dobutrex echocardiography (DEC) in diagnosis of myocardial ischemia and viability, in prognostication of angina pectoris and myocardial infarction (MI), evaluation of DEC side effects. MATERIAL AND METHODS: DEC was conducted in 74 patients with unconfirmed diagnosis (they had ischemic heart disease risk factors, atypical cardialgia) and 32 ischemic heart disease patients. RESULTS: DEC proved to be an effective diagnostic tool in diagnosis of myocardial ischemia in patients with new-onset atypical cardialgia (informative value 73.6%). This test gives prognosis of the disease and improves treatment policy in patients with angina of effort and MI. The most serious and frequent side effects of DEC arising at the highest dobutrex dose were paroxysmal tachycardias (3.76%) and ventricular arrhythmias (6.58%). In most cases (99.1%) they discontinued after the test and did not require antiarrhythmic treatment. Thus, the test is relatively safe. CONCLUSION: Echocardiography with dobutrex load should be used in practical cardiology more intensively.

[A comparative evaluation of the efficacy of magneto- and laser therapy in patients with osteoarthrosis deformans]. / Sravnitel'naia otsenka éffektivnosti magnito- i lazeroterapii bol'nykh deformiruiushchim osteoartrozom.

A comparative evaluation of efficacy of magneto- and laser therapy was carried out in 82 patients with osteoarthrosis deformans. The magnetic field and laser irradiation dispelled the pain syndrome and synovitis manifestations. It is recommendable that the multiple-modality therapy of patients with osteoarthrosis deformans should involve magneto- and laser therapy (15 to 20 procedures per one course) that improve results of the treatment being received and allow the time of hospitalization to be reduced at an average by 5 bed-days. Laser appeared to be a very effective mode of treatment. No unfavourable side effects were recordable.

[Methodological bases for the training of a therapist in cardiology in light of physician certification]. / Metodicheskie osnovy podgotovki terapevta po kardiologii v svete attestatsii vrachei.

In the course of theoretical education, one of the most important forms is that of lectures, particularly generalizing and problem-solving ones. Practical education (two thirds of the working time) will include the following: keeping patients under observation; practical studies; clinical and clinicoanatomical conferences; professor's rounds; going on duty by departments; participation in conducting and mastering the instrumental methods of investigation. The role of the audience at the lectures is an active one, that of the teacher is to direct and correct. Special attention is payed to individual work of a physician. All of the aforementioned kinds of work will, we believe, help the physician in making progress, upgrading his clinical mentality, attaining knowledge, skills, deontological principles in work. Use of test questions in cardiology approved by Ministry of Health of Ukraine as a national programme for certification of physicians together with the traditional methods of teaching will improve the quality of physician training.

[The diagnosis and treatment of osteoarthrosis deformans in subjects in contact with fluorine compounds]. / Diagnostika i lechenie deformiruiushchego osteoartroza u lits, kontaktirovavshikh s soedineniiami ftora.

A comparative study is presented of 378 workers with osteoarthrosis deformans (OD) contacting with fluorine compounds and in 106 patients with primary OD. The diagnostic criteria in these two categories of patients coincided. But the pain syndrome in the joints in professional fluorosis (PF) was associated with ossalgias (85%), tenderness of the bones (50.1%) and in 100% by symmetric hyperostosis. OD in PF was accompanied by a more pronounced density, was not accompanied by formation of nodes, and secondary synovitis was 4 times frequent. In OD plus PF males prevailed (96.7 e), and were averagely 10 years younger. In OD+PF treatment diet, calcium agents, glutamic acid should be used that bind and excrete fluorine from the body.

[Early diagnosis and classification of occupational fluorosis]. / Ranniaia diagnostika i klassifikatsiia professional'nogo fliuoroza.

On the basis of evaluating the clinical course and supplementary method of examination carried out in 132 patients suffering of professional fluorosis and in 200 workers in the premorbid state the author proposes criteria of early diagnosis. Considering Zislin's classification of professional fluorosis, literature data and own findings the author introduces 2 new criteria in the classification, namely, content of fluorine in the urine and length of work in this profession.

[A comparative assessment of gastric secretory function using a probe method and intragastric Ph-metry]. / Sravnitel'naia otsenka sekretornoi funktsii zheludka, izuchaemoi zondovym metodom i intragastral'noi Ph-metriei.

To compare informative value of probing and intragastric pH-metry, relevant examination was performed in 130 patients with chronic gastritis, 132 patients with noncomplicated peptic ulcer and 50 healthy subjects. pH values obtained with probing and intragastric pH-metry did not differ significantly in defects of gastric mucosa, superficial gastritis, peptic ulcer. In apparent atrophic gastritis intragastric pH-metry detected minimal secretion of H ions in all the patients, whereas probing failed to show it. Intragastric pH-metry is useful in recognizing duodenogastric reflux and decompensated acid stomach as shown by antral basal pH (below 2.0).