RESUMO
BACKGROUND: The Oxidative Balance Score (OBS) is a systematic tool to assess the effects of diet and lifestyle in relation to oxidative stress. The association between OBS and gout has not been reported previously. We conducted a cross-sectional study to investigate the complex association between OBS and gout in US adults. METHODS: In all, 10 492 participants were included in this study. The exposure variable was OBS, which was scored by 16 dietary and four lifestyle factors. Multivariate logistic regression, subgroup analysis, and restricted cubic spline (RCS) regression were used to analyze the association between OBS and gout. RESULTS: Compared with the lowest OBS quartile group (Q1), the multivariate corrected odds ratio (OR) (95% confidence interval [C]) for the highest quartile of OBS (Q4) was 0.72 (0.52-1.00) (p = .13 for trend); furthermore, the RCS showed a negative linear relationship between OBS and gout (p-nonlinear = .606). CONCLUSION: In conclusion, the risk of gout is higher with high OBS. The prevalence of gout decreased with higher OBS. Diabetes may alter this negative correlation.
Assuntos
Gota , Inquéritos Nutricionais , Estresse Oxidativo , Humanos , Gota/epidemiologia , Gota/diagnóstico , Estudos Transversais , Masculino , Feminino , Pessoa de Meia-Idade , Fatores de Risco , Estados Unidos/epidemiologia , Adulto , Prevalência , Estilo de Vida , Medição de Risco , Dieta/efeitos adversos , IdosoAssuntos
Psoríase , Humanos , Estudos Transversais , Psoríase/diagnóstico , Psoríase/complicações , Masculino , Feminino , Pessoa de Meia-Idade , Adulto , Disfunções Sexuais Fisiológicas/diagnóstico , Disfunções Sexuais Fisiológicas/etiologia , Disfunções Sexuais Fisiológicas/epidemiologia , Inquéritos e Questionários/estatística & dados numéricos , Qualidade de Vida , IdosoAssuntos
Síndrome de Hiperostose Adquirida , Síndrome do Desfiladeiro Torácico , Humanos , Síndrome do Desfiladeiro Torácico/etiologia , Síndrome do Desfiladeiro Torácico/diagnóstico , Síndrome de Hiperostose Adquirida/complicações , Síndrome de Hiperostose Adquirida/diagnóstico , Resultado do Tratamento , Feminino , Pessoa de Meia-IdadeRESUMO
BACKGROUND: Oxidative stress is associated with risk of pathogenesis between rheumatoid arthritis. The Oxidative Balance Score (OBS) is a systematic tool to assess the effects of diet and lifestyle in relation to oxidative stress. However, the association between OBS and rheumatoid arthritis has not been reported previously. We conducted a cross-sectional study to investigate the complex association between OBS and rheumatoid arthritis in US adults. METHODS: Overall, 9747 participants were included in this cross-sectional study. The exposure variable was OBS, which was scored by 16 dietary and four lifestyle factors. Multivariate logistic regression, subgroup analysis, and restricted cubic spline (RCS) regression were used to analyze the association between OBS and rheumatoid arthritis. RESULTS: Compared to the lowest OBS quartile group (Q1), the multivariate corrected odds ratio (OR) (95% confidence interval [CI]) for the highest quartile of OBS (Q4) was 0.69 (0.52-0.90) (p = .013 for trend); furthermore, the RCS showed a negative linear relationship between OBS and rheumatoid arthritis. According to subgroup and RCS analyses, there was a significant difference between the association of OBS and with rheumatoid arthritis in terms of gender (p = .049). CONCLUSION: In conclusion, high OBS was negatively associated with the risk of rheumatoid arthritis. Gender has an effect on OBS in RA. Our results suggest that OBS can be used as a biomarker to predict rheumatoid arthritis.
Assuntos
Artrite Reumatoide , Inquéritos Nutricionais , Estresse Oxidativo , Humanos , Artrite Reumatoide/epidemiologia , Artrite Reumatoide/diagnóstico , Feminino , Masculino , Estudos Transversais , Pessoa de Meia-Idade , Fatores de Risco , Estados Unidos/epidemiologia , Fatores Sexuais , Adulto , Medição de Risco , Estilo de Vida , Idoso , Análise Multivariada , Dieta/efeitos adversosAssuntos
Síndrome de Hiperostose Adquirida , Tálus , Ossos do Tarso , Humanos , Tálus/diagnóstico por imagem , Tálus/patologia , Síndrome de Hiperostose Adquirida/diagnóstico por imagem , Síndrome de Hiperostose Adquirida/diagnóstico , Ossos do Tarso/diagnóstico por imagem , Ossos do Tarso/patologia , Feminino , Calcanhar , Pessoa de Meia-Idade , Radiografia , MasculinoRESUMO
This paper provides a viewpoint of the technology of the fast-scanning calorimetry with the relaxation behavior of disordered side chains of poly[2,5-bis(3-dodecylthiophen-2-yl)thieno[3,2-b]thiophene] (PBTTT-C12) around the glass transition temperature of the side chains (Tg,γ). PBTTT is an ideal model of the high-performance copolymer of poly(alkylthiophenes) with side chains. The γ1 relaxation process of the disordered side chains of PBTTT was detected as a small endothermic peak that emerges before the γ2 relaxation process. It shows an increase with increasing temperature as it approaches the glass transition temperature of the disordered side chains of PBTTT. The ductile-brittle transition of PBTTT in low temperatures originating from the thermal relaxation process is probed and illustrated by physical aging experiments. The signature is shown that the relaxation process of the disordered side chain of PBTTT at low temperatures varies from Arrhenius temperature dependence to super Arrhenius temperature dependence at high temperatures. These observations could have significant consequences for the stability of devices based on conjugated polymers, especially those utilized for stretchable or flexible applications, or those demanding mechanical robustness during tensile fabrication or use in a low-temperature environment.