Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 5 de 5
Filtrar
1.
Sci Rep ; 14(1): 12050, 2024 May 27.
Artigo em Inglês | MEDLINE | ID: mdl-38802516

RESUMO

Micro-light-emitting diodes (Micro-LEDs) are a new type of display device based on the third-generation semiconductor gallium nitride (GaN) material which stands out for its high luminous efficiency, elevated brightness, short response times, and high reliability. The contact between anode layers and P-GaN is one of the keys to improving the performance of the devices. This study investigates the impact of electrode structure design and optimized annealing conditions on the anode contact performance of devices. The Micro-LED device with the size of 9.1 µm whose electrode structure is ITO/Ti/Al/Ni/Cr/Pt/Au (100/50/350/100/500/500/5000 Å) exhibits a significant improvement in contact performance after annealing under the Ar gas atmosphere at 500 °C for 5 min. The optimized device exhibited a current of 10.9 mA and a brightness of 298,628 cd/m2 under 5 V. The EQE peak value of Device A is 10.06% at 400 mA.

2.
Hum Vaccin Immunother ; 19(2): 2223108, 2023 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-37350470

RESUMO

Population movements had a significant impact on the spread of COVID-19, and vaccination is considered the most effective means for humans to face viral infections. This study identifies the optimal control strategy for COVID-19 prevention and control, and explores the impact of short-term and long-term migration on the optimal proportion of vaccine allocation between two regions. We proposed to establish the SIR (Susceptible-Infectious-Recovered) model and determine the stability by calculating the disease free equilibrium and Jacobi matrix of the model. We then established the vaccine optimization model, solved the optimal vaccine distribution strategy by gradient descent method and explored the impact of short-term and long-term migration on the optimal vaccine allocation ratio. The stability analysis revealed that the virus could not be eliminated only by reducing the migration rates and infection rates. we introduced the vaccine methods and obtained the optimal vaccine allocation ratio in Shenzhen and Hong Kong as p1:p2=0.000341: 0.001739, and the daily vaccination rate we need to impose in each region as p1:p2=0.00068:0.001901. The presence or absence of short-term migration had no greater impact on the distribution of the vaccine, whereas Rv with long-term migration had a greater effect than no migration. We found that migration rates could not eliminate the outbreak in both regions and that adopting an effective vaccine distribution strategy could be more effective in eliminating the outbreak. And for different allocation scenarios with limited vaccine supply, we obtained the optimal allocation most favorable to control the epidemic.


Assuntos
COVID-19 , Epidemias , Vacinas contra Influenza , Humanos , COVID-19/epidemiologia , COVID-19/prevenção & controle , Vacinação/métodos , Surtos de Doenças , Epidemias/prevenção & controle
3.
Front Public Health ; 10: 876551, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35784231

RESUMO

The vaccines are considered to be important for the prevention and control of coronavirus disease 2019 (COVID-19). However, considering the limited vaccine supply within an extended period of time in many countries where COVID-19 vaccine booster shot are taken and new vaccines are developed to suppress the mutation of virus, designing an effective vaccination strategy is extremely important to reduce the number of deaths and infections. Then, the simulations were implemented to study the relative reduction in morbidity and mortality of vaccine allocation strategies by using the proposed model and actual South Africa's epidemiological data. Our results indicated that in light of South Africa's demographics, vaccinating older age groups (>60 years) largely reduced the cumulative deaths and the "0-20 first" strategy was the most effective way to reduce confirmed cases. In addition, "21-30 first" and "31-40 first" strategies have also had a positive effect. Partial vaccination resulted in lower numbers of infections and deaths under different control measures compared with full vaccination in low-income countries. In addition, we analyzed the sensitivity of daily testing volume and infection rate, which are critical to optimize vaccine allocation. However, comprehensive reduction in infections was mainly affected by the vaccine proportion of the target age group. An increase in the proportion of vaccines given priority to "0-20" groups always had a favorable effect, and the prioritizing vaccine allocation among the "60+" age group with 60% of the total amount of vaccine consistently resulted in the greatest reduction in deaths. Meanwhile, we observed a significant distinction in the effect of COVID-19 vaccine allocation policies under varying priority strategies on relative reductions in the effective reproduction number. Our results could help evaluate to control measures performance and the improvement of vaccine allocation strategy for COVID-19 epidemic.


Assuntos
COVID-19 , Fatores Etários , Idoso , COVID-19/prevenção & controle , Vacinas contra COVID-19 , Humanos , Imunização Secundária , África do Sul/epidemiologia , Vacinação
4.
Infect Genet Evol ; 98: 105218, 2022 03.
Artigo em Inglês | MEDLINE | ID: mdl-35066164

RESUMO

BACKGROUND: The widespread use of effective COVID-19 vaccines could prevent substantial morbidity and mortality. Individual decision behavior about whether or not to be vaccinated plays an important role in achieving adequate vaccination coverage and herd immunity. METHODS: This research proposes a new susceptible-vaccinated-exposed-infected-recovered with awareness-information (SEIR/V-AI) model to study the interaction between vaccination and information dissemination. Information creation rate and information sensitivity are introduced to understand the individual decision behavior of COVID-19 vaccination. We then analyze the dynamical evolution of the system and validate the analysis by numerical simulation. RESULTS: The decision behavior of COVID-19 vaccination in China and the United States are analyzed. The results showed the coefficient of information creation and the information sensitivity affect vaccination behavior of individuals. CONCLUSIONS: The information-driven vaccination is an effective way to curb the COVID-19 spreading. Besides, to solve vaccine hesitancy and free-ride, the government needs to disseminate accurate information about vaccines safety to alleviate public concerns, and provide the widespread public educational campaigns and communication to guide individuals to act in group interests rather than self-interest and reduce the temptation to free-riding, which often results from individuals who are inadequately informed about vaccines and thus blindly imitate free-riding behavior.


Assuntos
Vacinas contra COVID-19/administração & dosagem , COVID-19/prevenção & controle , Aceitação pelo Paciente de Cuidados de Saúde/psicologia , Aceitação pelo Paciente de Cuidados de Saúde/estatística & dados numéricos , SARS-CoV-2/efeitos dos fármacos , Vacinação/psicologia , Vacinação/estatística & dados numéricos , COVID-19/epidemiologia , Humanos , Modelos Teóricos , Estados Unidos/epidemiologia
5.
J Med Virol ; 93(7): 4342-4350, 2021 07.
Artigo em Inglês | MEDLINE | ID: mdl-33738825

RESUMO

In this paper, we propose a new susceptible-vaccinated-exposed-infected-recovered with unaware-aware (SEIR/V-UA) model to study the mutual effect between the epidemic spreading and information diffusion. We investigate the dynamic processes of the model with a Kinetic equation and derive the expression for epidemic stability by the eigenvalues of the Jacobian matrix. Then, we validate the model by the Monte Carlo method and numerical simulation on a two-layer scale-free network. With the outbreak of COVID-19, the spread of the epidemic in China prompted drastic measures for transmission containment. We examine the effects of these interventions based on modeling of the information-epidemic and the data of the COVID-19 epidemic case. The results further demonstrate that the epidemic spread can be affected by the effective transmission rate of awareness.


Assuntos
COVID-19/epidemiologia , COVID-19/transmissão , Controle de Doenças Transmissíveis/métodos , Conhecimentos, Atitudes e Prática em Saúde , Educação de Pacientes como Assunto/métodos , COVID-19/patologia , China/epidemiologia , Humanos , Modelos Estatísticos , SARS-CoV-2
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA