A liquid metal-polydopamine composite for cell culture and electro-stimulation.

Gallium (Ga) is a low melting point metal in the liquid state in the biological environment which presents a unique combination of fluidity, softness, and metallic electrical and thermal properties. In this work, liquid Ga is proposed as a biocompatible electrode material for cell culture by electro-stimulation since the cytotoxicity of Ga is generally considered low and some Ga compounds have been reported to exhibit anti-bacterial and anti-inflammatory activities. Complementarily, polydopamine (PDA) was coated on liquid Ga to increase the attachment capability of cells on the liquid Ga electrode and provide enhanced biocompatibility. The liquid Ga layer could be readily painted at room temperature on a solid inert substrate, followed by the formation of a nanoscale PDA coating layer resulting in a conformable and biocompatible composite electrode. The PDA layer was shown to coordinate with Ga3+, which is sourced from liquid Ga, providing electrical conductivity in the cell culture medium. The PDA-Ga3+ composite acted as a conductive substrate for advanced electro-stimulation for cell culture methods of representative animal fibroblasts. The cell proliferation was observed to increase by ∼143% as compared to a standard glass coverslip at a low potential of 0.1 V of direct coupling stimulation. This novel PDA-Ga3+ composite has potential applications in cell culture and regenerative medicine.

Liquid Metal-Templated Tin-Doped Tellurium Films for Flexible Asymmetric Pseudocapacitors.

Liquid metals can be surface activated to generate a controlled galvanic potential by immersing them in aqueous solutions. This creates energized liquid-liquid interfaces that can promote interfacial chemical reactions. Here we utilize this interfacial phenomenon of liquid metals to deposit thin films of tin-doped tellurium onto rigid and flexible substrates. This is accomplished by exposing liquid metals to a precursor solution of Sn2+ and HTeO2+ ions. The ability to paint liquid metals onto substrates enables us to fabricate supercapacitor electrodes of liquid metal films with an intimately connected surface layer of tin-doped tellurium. The tin-doped tellurium exhibits a pseudocapacitive behavior in 1.0 M Na2SO4 electrolyte and records a specific capacitance of 184.06 F·g-1 (5.74 mF·cm-2) at a scan rate of 10 mV·s-1. Flexible supercapacitor electrodes are also fabricated by painting liquid metals onto polypropylene sheets and subsequently depositing tin-doped tellurium thin films. These flexible electrodes show outstanding mechanical stability even when experiencing a complete 180° bend as well as exhibit high power and energy densities of 160 W·cm-3 and 31 mWh·cm-3, respectively. Overall, this study demonstrates the attractive features of liquid metals in creating energy storage devices and exemplifies their use as media for synthesizing electrochemically active materials.

Polydopamine Shell as a Ga3+ Reservoir for Triggering Gallium-Indium Phase Separation in Eutectic Gallium-Indium Nanoalloys.

Low melting point eutectic systems, such as the eutectic gallium-indium (EGaIn) alloy, offer great potential in the domain of nanometallurgy; however, many of their interfacial behaviors remain to be explored. Here, a compositional change of EGaIn nanoalloys triggered by polydopamine (PDA) coating is demonstrated. Incorporating PDA on the surface of EGaIn nanoalloys renders core-shell nanostructures that accompany Ga-In phase separation within the nanoalloys. The PDA shell keeps depleting the Ga3+ from the EGaIn nanoalloys when the synthesis proceeds, leading to a Ga3+-coordinated PDA coating and a smaller nanoalloy. During this process, the eutectic nanoalloys turn into non-eutectic systems that ultimately result in the solidification of In when Ga is fully depleted. The reaction of Ga3+-coordinated PDA-coated nanoalloys with nitrogen dioxide gas is presented as an example for demonstrating the functionality of such hybrid composites. The concept of phase-separating systems, with polymeric reservoirs, may lead to tailored materials and can be explored on a variety of post-transition metals.

Nanotip Formation from Liquid Metals for Soft Electronic Junctions.

Liquid metals and alloys with high-aspect-ratio nanodimensional features are highly sought-after for emerging electronic applications. However, high surface tension, water-like fluidity, and the existence of self-limiting oxides confer specific peculiarities to their characteristics. Here, we introduce a high accuracy nanometric three-dimensional pulling and stretching method to fabricate liquid-metal-based nanotips from room- or near-room-temperature gallium-based alloys. The pulling rate and step size were controlled with a resolution of up to 10 nm and yielded different nanotip morphologies and lengths as a function of the base liquid metal alloy composition and the pulling parameters. The obtained nanotips presented high aspect ratios over lengths of a few microns and apexes between 10 and 100 nm. The liquid metal alloys were found confined within nanotips with about 10 nm apexes when vertically pulled at 100 nm/s. An amorphous gallium oxide skin was shown to cover the surface of the nanotips, while the liquid core was composed of the initial liquid metal alloys. The electrical contact established at the nanotips was characterized under dynamic conditions. The liquid metal nanotips showed an Ohmic resistance when a continuous liquid metal channel was formed, and a controllable semiconductor state corresponding to a heterojunction formed at the junction between the liquid metal phase and the gallium oxide semiconductor skin. The variable threshold voltages of the heterojunction were controlled via stretching of the nanotips with a 10 nm step resolution. The liquid metal nanotips were also used for establishing soft electronic junctions. This novel method of liquid metal nanotip fabrication with Ohmic and semiconducting behaviors will lead to exciting avenues for developing electronic and sensing devices.

Bi-Sn Catalytic Foam Governed by Nanometallurgy of Liquid Metals.

Metallic foams, with intrinsic catalytic properties, are critical for heterogeneous catalysis reactions and reactor designs. Market ready catalytic foams are costly and made of multimaterial coatings with large sub-millimeter open cells providing insufficient active surface area. Here we use the principle of nanometallurgy within liquid metals to prepare nanostructured catalytic metal foams using a low-cost alloy of bismuth and tin with sub-micrometer open cells. The eutectic bismuth and tin liquid metal alloy was processed into nanoparticles and blown into a tin and bismuth nanophase separated heterostructure in aqueous media at room temperature and using an indium brazing agent. The CO2 electroconversion efficiency of the catalytic foam is presented with an impressive 82% conversion efficiency toward formates at high current density of -25 mA cm-2 (-1.2 V vs RHE). Nanometallurgical process applied to liquid metals will lead to exciting possibilities for expanding industrial and research accessibility of catalytic foams.

Magnetic and Conductive Liquid Metal Gels.

Liquid metals are fast becoming a new class of universal and frictionless additives for the development of multifunctional soft and flexible materials. Herein, nanodroplets of eutectic gallium-indium alloy, which is liquid at room temperature, were used as a platform for the formulation of electrically conductive and magnetically responsive gels with the incorporation of Fe3O4 nanoparticles. The nanoadditives were prepared in situ within a water-based solution of polyvinyl alcohol. A borax cross-linking reaction was then performed to yield multifunctional flexible and self-healing gels. The physicochemical properties and changes in the nanoadditives at each step of the gel preparation method were characterized. Oxidation and complexation reactions between the liquid metal and iron oxide nanoadditives were observed. A mixture of nanosized functional magnetic Fe3O4/Fe2O3 and In-Fe oxide complexes was found to enable the magnetic susceptibility of the gels. The mechanical and self-healing properties of the gels were assessed, and finally, this flexible and multifunctional material was used as an electronic switch via remote magnetic actuation. The developed conductive and magnetic gels demonstrate great potential for the design of soft electronic systems.