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1.
Med Biol Eng Comput ; 2024 Jun 19.
Artigo em Inglês | MEDLINE | ID: mdl-38898201

RESUMO

Total hip replacement (THR) with cemented stem is a common procedure for patients with hip osteoarthritis. When primary THR fails, removal of the cement is problematic and poses challenges during revision surgeries. The possibility of proximal partial cementing of the hip stem was explored to mitigate the problem. 3D finite element analysis was performed to investigate the feasibility of reduced cement length for effective implant fixation and load transmission. Three levels of cement reduction (40 mm, 80 mm, and 100 mm) in the femoral stem were evaluated. All models were assigned loadings of peak forces acting on the femur during walking and stair climbing. The experimental and predicted max/min principal bone strains were fitted into regression models and showed good correlations. FE results indicated stress increment in the femoral bone, stem, and cement due to cement reduction. A notable increase of bone stress was observed with large cement reduction of 80-100 mm, particularly in Gruen zones 3 and 5 during walking and Gruen zones 3 and 6 during stair climbing. The increase of cement stresses could be limited to 11% with a cement reduction of 40 mm. The findings suggested that a 40-mm cement reduction in hip stem fixation was desirable to avoid unwanted complications after cemented THR.

2.
Orthopedics ; 45(5): 314-319, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35576486

RESUMO

Total knee arthroplasty surgery is an increasingly common procedure for the treatment of uni- and tricompartmental knee osteoarthritis, particularly in advanced stages and in the older population. Its usage is being extended to younger patients, where implant longevity is of concern. In the younger age group, especially with early disease, other options merit consideration. On the other hand, it may not be possible for elderly patients with medical comorbidities to undergo joint replacement surgery. Proximal fibular osteotomy (PFO) has recently been advocated to treat medial knee osteoarthritis. Although there have been clinical reports showing promising outcomes, the biomechanical basis of this procedure is still unclear. We performed a cadaveric study to investigate the effect of PFO on proximal tibial strain. Eight unpaired cadaveric lower limb specimens were loaded in compression at 2 times body weight. Strain gauges were mounted on various sites on the proximal tibia and fibula. After PFO, there was a significant increase in the lateral tibial strain adjacent to the proximal tibiofibular joint (P<.05). There was moderate effect size reduction in the anteromedial tibial strain as well as moderate effect size increase in the posterior tibial strain. The strain reduction seen at the anteromedial tibia can offer a possible explanation for symptomatic relief after PFO. However, the increase in the lateral and posterior tibial strain raises concern about long-term accelerated wear in these regions. [Orthopedics. 2022;45(5):314-319.].


Assuntos
Osteoartrite do Joelho , Tíbia , Idoso , Cadáver , Fíbula/cirurgia , Humanos , Articulação do Joelho/cirurgia , Osteoartrite do Joelho/cirurgia , Osteotomia/métodos , Tíbia/cirurgia
3.
J Knee Surg ; 35(3): 280-287, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-32629512

RESUMO

BACKGROUND: Restoration of the anatomical joint line, while important for clinical outcomes, is difficult to achieve in revision total knee arthroplasty (rTKA) due to distal femoral bone loss. The objective of this study was to determine a reliable method of restoring the anatomical joint line and posterior condylar offset in the setting of rTKA based on three-dimensional (3D) reconstruction of computed tomography (CT) images of the distal femur. METHODS: CT scans of 50 lower limbs were analyzed. Key anatomical landmarks such as the medial epicondyle (ME), lateral epicondyle, and transepicondylar width (TEW) were determined on 3D models constructed from the CT images. Best-fit planes placed on the most distal and posterior loci of points on the femoral condyles were used to define the distal and posterior joint lines, respectively. Statistical analysis was performed to determine the relationships between the anatomical landmarks and the distal and posterior joint lines. RESULTS: There was a strong correlation between the distance from the ME to the distal joint line of the medial condyle (MEDC) and the distance from the ME to the posterior joint line of the medial condyle (MEPC) (p < 0.001; r = 0.865). The mean ratio of MEPC to MEDC was 1.06 (standard deviation [SD]: 0.07; range: 0.88-1.27) and that of MEPC to TEW was 0.33 (SD: 0.03; range: 0.25-0.38). CONCLUSIONS: Our findings suggest that the fixed ratios of MEPC to TEW (0.33) and that of MEPC to MEDC (1.06) provide a reliable means for the surgeon to determine the anatomical joint line when used in combination.


Assuntos
Artroplastia do Joelho , Articulação do Joelho , Fêmur/diagnóstico por imagem , Fêmur/cirurgia , Humanos , Articulação do Joelho/diagnóstico por imagem , Articulação do Joelho/cirurgia , Tomografia Computadorizada por Raios X
4.
Jt Dis Relat Surg ; 32(1): 239-244, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33463444

RESUMO

Injuries to the pelvic vasculature during total hip arthroplasties are rare but have serious consequence. They demand urgent and early identification so that appropriate treatment can be instituted. If the bleeding is severe, cardiovascular compromise occurs intraoperatively and this will alert the surgeon of this possibility during acetabular screw placement. Alternatively, a delay in diagnosis can occur because the bleeding and the injured vessel are in the pelvic cavity and not visualized during the surgery. In this article, we report two cases from our center occurring within a six-month interval that sustained a vascular injury during acetabular drilling for screw placement for cementless cup fixation. Each case had a different vessel injury and different lessons can be learned from these rare injuries. The first case had an injury of the inferior gluteal artery following a breach of the sciatic notch. The vessel was treated with percutaneous embolization. The second case demonstrated a venous injury, following a medial protrusio technique for congenital hip dysplasia and a short anterosuperior screw, transecting the external iliac vein. This was subsequently repaired using an endovascular technique. We conclude the reasons for these vessel injuries after analyzing advanced imaging, discuss measures to avoid vessel injury and detail the minimally invasive method for their treatment.


Assuntos
Acetábulo , Artroplastia de Quadril , Embolização Terapêutica/métodos , Procedimentos Endovasculares/métodos , Complicações Intraoperatórias , Pelve , Lesões do Sistema Vascular , Acetábulo/diagnóstico por imagem , Acetábulo/cirurgia , Artroplastia de Quadril/efeitos adversos , Artroplastia de Quadril/instrumentação , Artroplastia de Quadril/métodos , Parafusos Ósseos , Feminino , Humanos , Complicações Intraoperatórias/diagnóstico , Complicações Intraoperatórias/etiologia , Complicações Intraoperatórias/prevenção & controle , Complicações Intraoperatórias/terapia , Masculino , Pessoa de Meia-Idade , Pelve/irrigação sanguínea , Pelve/cirurgia , Cuidados Pré-Operatórios/métodos , Risco Ajustado/métodos , Lesões do Sistema Vascular/diagnóstico , Lesões do Sistema Vascular/etiologia , Lesões do Sistema Vascular/prevenção & controle , Lesões do Sistema Vascular/terapia
5.
Clin Biomech (Bristol, Avon) ; 79: 105178, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32988676

RESUMO

BACKGROUND: Cartilage damage, which can potentially lead to osteoarthritis, is a leading cause of morbidity in the elderly population. Chondrocytes are sensitive to mechanical stimuli and their matrix-protein synthesis may be altered when chondrocytes experience a variety of in vivo loadings. Therefore, a study was conducted to evaluate the biosynthesis of isolated osteoarthritic chondrocytes which subjected to compression with varying dynamic compressive strains and loading durations. METHODS: The proximal tibia was resected as a single osteochondral unit during total knee replacement from patients (N = 10). The osteoarthritic chondrocytes were isolated from the osteochondral units, and characterized using reverse transcriptase-polymerase chain reaction. The isolated osteoarthritic chondrocytes were cultured and embedded in agarose, and then subjected to 10% and 20% uniaxial dynamic compression up to 8-days using a bioreactor. The morphological features and changes in the osteoarthritic chondrocytes upon compression were evaluated using scanning electron microscopy. Safranin O was used to detect the presence of cartilage matrix proteoglycan expression while quantitative analysis was conducted by measuring type VI collagen using an immunohistochemistry and fluorescence intensity assay. FINDINGS: Gene expression analysis indicated that the isolated osteoarthritic chondrocytes expressed chondrocyte-specific markers, including BGN, CD90 and HSPG-2. Moreover, the compressed osteoarthritic chondrocytes showed a more intense and broader deposition of proteoglycan and type VI collagen than control. The expression of type VI collagen was directly proportional to the duration of compression in which 8-days compression was significantly higher than 4-days compression. The 20% compression showed significantly higher intensity compared to 10% compression in 4- and 8-days. INTERPRETATION: The biosynthetic activity of human chondrocytes from osteoarthritic joints can be enhanced using selected compression regimes.


Assuntos
Condrócitos/patologia , Fenômenos Mecânicos , Osteoartrite/patologia , Idoso , Fenômenos Biomecânicos , Cartilagem Articular/patologia , Condrócitos/metabolismo , Humanos , Masculino , Pessoa de Meia-Idade , Osteoartrite/metabolismo , Proteoglicanas/metabolismo , Estresse Mecânico
6.
J Arthroplasty ; 33(6): 1936-1944, 2018 06.
Artigo em Inglês | MEDLINE | ID: mdl-29395720

RESUMO

BACKGROUND: We hypothesized that there is a correlation between the distal femoral rotation and proximal tibial joint line obliquity in nonarthritic knees. This has significance for kinematic knee arthroplasty, in which the target knee alignment desired approximates the knee before disease. METHODS: Fifty computed tomography scans of nonarthritic knees were evaluated using three-dimensional image processing software. Four distal femoral rotational axes were determined in the axial plane: the transepicondylar axis (TEA), transcondylar axis (TCA), posterior condylar axis (PCA), and a line perpendicular to Whiteside's anterior-posterior axis. Then, angles were measured relative to the TEA. Tibial joint line obliquity was measured as the angle between the proximal tibial plane and a line perpendicular to the axis of the tibia. RESULTS: There was a strong positive correlation between PCA-TEA and tibial joint line obliquity (r = 0.68, P < .001) as well as TCA-TEA and tibial joint line obliquity (r = 0.69, P < .001). In addition, the tibial joint line obliquity and TCA-TEA angles were similar, 3.7° ± 2.2° (mean ± standard deviation) and 3.5° ± 1.7°, respectively (mean difference, 0.2° ± 0.2°; P = .369). CONCLUSION: Both PCA-TEA and TCA-TEA strongly correlated with proximal tibial joint line obliquity indicating a relationship between distal femoral rotational geometry and proximal tibial inclination. These findings could imply that the native knee in flexion attempts to balance the collateral ligaments toward a rectangular flexion space. A higher tibial varus inclination is matched with a more internally rotated distal femur relative to the TEA.


Assuntos
Artroplastia do Joelho/métodos , Fêmur/cirurgia , Articulação do Joelho/cirurgia , Osteoartrite do Joelho/cirurgia , Tíbia/cirurgia , Idoso , Fenômenos Biomecânicos , Feminino , Fraturas Ósseas/cirurgia , Humanos , Imageamento Tridimensional , Masculino , Pessoa de Meia-Idade , Amplitude de Movimento Articular , Reprodutibilidade dos Testes , Rotação , Software , Tomografia Computadorizada por Raios X
7.
J Arthroplasty ; 32(10): 3176-3183, 2017 10.
Artigo em Inglês | MEDLINE | ID: mdl-28579444

RESUMO

BACKGROUND: The posterior tibial slope (PTS) is an important consideration in knee arthroplasty. However, there is still no consensus for the optimal slope. The objectives of this study were (1) to reliably determine the native PTS in this population using 3-dimensional computed tomography scans and (2) to determine the normal reference range for PTS in this population. METHODS: One hundred computed tomography scans of disease-free knees were analyzed. A 3-dimensional reconstructed image of the tibia was generated and aligned to its anatomic axis in the coronal and sagittal planes. The tibia was then rotationally aligned to the tibial plateau (tibial centroid axis) and PTS was measured from best-fit planes on the surface of the proximal tibia and individually for the medial and lateral plateaus. This was then repeated with the tibia rotationally aligned to the ankle (transmalleolar axis). RESULTS: When rotationally aligned to the tibial plateau, the mean PTS, medial PTS, and lateral PTS were 11.2° ± 3.0 (range, 4.7°-17.7°), 11.3° ± 3.2 (range, 2.7°-19.7°), and 10.9° ± 3.7 (range, 3.5°-19.4°), respectively. When rotationally aligned to the ankle, the mean PTS, medial PTS, and lateral PTS were 11.4° ± 3.0 (range, 5.3°-19.3°), 13.9° ± 3.7 (range, 3.1°-24.4°), and 9.7° ± 3.6 (range, 0.8°-17.7°), respectively. CONCLUSION: The PTS in the normal Asian knee is on average 11° (mean) with a reference range of 5°-17° (mean ± 2 standard deviation). This has implications to surgery and implant design.


Assuntos
Articulação do Joelho/diagnóstico por imagem , Tíbia/diagnóstico por imagem , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Articulação do Tornozelo , Artroplastia do Joelho , Povo Asiático/estatística & dados numéricos , Feminino , Humanos , Imageamento Tridimensional/métodos , Joelho , Masculino , Pessoa de Meia-Idade , Valores de Referência , Tomografia Computadorizada por Raios X/métodos , Adulto Jovem
8.
PLoS One ; 12(6): e0178117, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28654695

RESUMO

The role for mechanical stimulation in the control of cell fate has been previously proposed, suggesting that there may be a role of mechanical conditioning in directing mesenchymal stromal cells (MSCs) towards specific lineage for tissue engineering applications. Although previous studies have reported that calcium signalling is involved in regulating many cellular processes in many cell types, its role in managing cellular responses to tensile loading (mechanotransduction) of MSCs has not been fully elucidated. In order to establish this, we disrupted calcium signalling by blocking stretch-activated calcium channel (SACC) in human MSCs (hMSCs) in vitro. Passaged-2 hMSCs were exposed to cyclic tensile loading (1 Hz + 8% for 6, 24, 48, and 72 hours) in the presence of the SACC blocker, gadolinium. Analyses include image observations of immunochemistry and immunofluorescence staining from extracellular matrix (ECM) production, and measuring related tenogenic and apoptosis gene marker expression. Uniaxial tensile loading increased the expression of tenogenic markers and ECM production. However, exposure to strain in the presence of 20 µM gadolinium reduced the induction of almost all tenogenic markers and ECM staining, suggesting that SACC acts as a mechanosensor in strain-induced hMSC tenogenic differentiation process. Although cell death was observed in prolonged stretching, it did not appear to be apoptosis mediated. In conclusion, the knowledge gained in this study by elucidating the role of calcium in MSC mechanotransduction processes, and that in prolonged stretching results in non-apoptosis mediated cell death may be potential useful for regenerative medicine applications.


Assuntos
Agonistas dos Canais de Cálcio/farmacologia , Diferenciação Celular/efeitos dos fármacos , Gadolínio/farmacologia , Células-Tronco Mesenquimais/efeitos dos fármacos , Estresse Mecânico , Idoso , Apoptose/efeitos dos fármacos , Caderinas/metabolismo , Células Cultivadas , Colágeno/metabolismo , Matriz Extracelular/metabolismo , Fibronectinas/metabolismo , Humanos , Mecanotransdução Celular/efeitos dos fármacos , Células-Tronco Mesenquimais/citologia , Células-Tronco Mesenquimais/metabolismo , Pessoa de Meia-Idade , Engenharia Tecidual
9.
Knee ; 24(3): 555-563, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28330756

RESUMO

BACKGROUND: Patellofemoral instability is a major cause of anterior knee pain. The aim of this study was to examine how the medial and lateral stability of the patellofemoral joint in the normal knee changes with knee flexion and measure its relationship to differences in femoral trochlear geometry. METHODS: Twelve fresh-frozen cadaveric knees were used. Five components of the quadriceps and the iliotibial band were loaded physiologically with 175N and 30N, respectively. The force required to displace the patella 10mm laterally and medially at 0°, 20°, 30°, 60° and 90° knee flexion was measured. Patellofemoral contact points at these knee flexion angles were marked. The trochlea cartilage geometry at these flexion angles was visualized by Computed Tomography imaging of the femora in air with no overlying tissue. The sulcus, medial and lateral facet angles were measured. The facet angles were measured relative to the posterior condylar datum. RESULTS: The lateral facet slope decreased progressively with flexion from 23°±3° (mean±S.D.) at 0° to 17±5° at 90°. While the medial facet angle increased progressively from 8°±8° to 36°±9° between 0° and 90°. Patellar lateral stability varied from 96±22N at 0°, to 77±23N at 20°, then to 101±27N at 90° knee flexion. Medial stability varied from 74±20N at 0° to 170±21N at 90°. There were significant correlations between the sulcus angle and the medial facet angle with medial stability (r=0.78, p<0.0001). CONCLUSIONS: These results provide objective evidence relating the changes of femoral profile geometry with knee flexion to patellofemoral stability.


Assuntos
Fêmur/anatomia & histologia , Fêmur/fisiologia , Articulação Patelofemoral/fisiologia , Fenômenos Biomecânicos/fisiologia , Cadáver , Cartilagem Articular/diagnóstico por imagem , Cartilagem Articular/fisiologia , Fêmur/diagnóstico por imagem , Humanos , Imageamento Tridimensional , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios X
10.
Arthroscopy ; 30(3): 335-43, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24581258

RESUMO

PURPOSE: The purpose of this study was to clarify the changes in the kinematics of the knee that result from isolated deficiency of the anteromedial (AM) or posterolateral (PL) bundle. METHODS: Fourteen cadaveric knees were mounted in a 6-df rig and tested using the following 5 loading conditions: 90-N anterior and posterior tibial loads, 5-Nm internal and external tibial torques, and a simulated pivot-shift test. Tibiofemoral kinematics during flexion-extension was recorded with an optical tracking system for (1) intact knees, (2) knees in which the isolated AM bundle was cut, (3) knees in which the isolated PL bundle was cut, and (4) anterior cruciate ligament (ACL)-deficient knees. The distances between the femoral and tibial attachments of the AM and PL bundles of the ACL were also calculated. RESULTS: Anterior translation laxity under an anterior tibial load, rotational laxity under an internal tibial torque, and anterior translation laxity under pivot-shift loading were significantly different between the knees with AM and PL bundle deficiencies (P < .024), but the changes were small: less than 3 mm or 1.5°. The AM bundle distance increased significantly more after an AM bundle tear (P = .004) than after a PL bundle tear in flexion. Cutting the PL bundle did not have a significant effect on the lengths between the bundle attachments. CONCLUSIONS: An isolated AM or PL bundle tear caused a small increase in laxity (<3 mm or <1.5°). CLINICAL RELEVANCE: If there is a clinically identifiable increase in laxity, then--in addition to the isolated tear of the AM or PL bundle--there must also be a tear of the other bundle of the ACL, or at least a partial tear.


Assuntos
Lesões do Ligamento Cruzado Anterior , Ligamento Cruzado Anterior/fisiopatologia , Instabilidade Articular/fisiopatologia , Articulação do Joelho/fisiopatologia , Adulto , Idoso , Fenômenos Biomecânicos , Cadáver , Feminino , Fêmur/fisiopatologia , Humanos , Pessoa de Meia-Idade , Amplitude de Movimento Articular , Tíbia/fisiopatologia , Torque
11.
Knee Surg Sports Traumatol Arthrosc ; 22(3): 526-33, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-23271038

RESUMO

PURPOSE: To study the effect of increasing patellar thickness (overstuffing) on patellofemoral kinematics in total knee arthroplasty and whether subsequent lateral retinacular release would restore the change in kinematics. METHODS: The quadriceps of eight fresh-frozen knees were loaded on a custom-made jig. Kinematic data were recorded using an optical tracking device for the native knee, following total knee arthroplasty (TKA), then with patellar thicknesses from -2 to +4 mm, during knee extension motion. Staged lateral retinacular releases were performed to examine the restoration of normal patellar kinematics. RESULTS: Compared to the native knee, TKA led to significant changes in patellofemoral kinematics, with significant increases in lateral shift, tilt and rotation. When patellar composite thickness was increased, the patella tilted further laterally. Lateral release partly corrected this lateral tilt but caused abnormal tibial external rotation. With complete release of the lateral retinaculum and capsule, the patella with an increased thickness of 4 mm remained more laterally tilted compared to the TKA with normal patellar thickness between 45° and 55° knee flexion and from 75° onwards. This was on average by 2.4° ± 2.9° (p < 0.05) and 2.°9 ± 3.0° (p < 0.01), respectively. Before the release, for those flexion ranges, the patella was tilted laterally by 4.7° ± 3.2° and 5.4° ± 2.7° more than in the TKA with matched patellar thickness. CONCLUSION: Patellar thickness affects patellofemoral kinematics after TKA. Although lateral tilt was partly corrected by lateral retinacular release, this affected the tibiofemoral kinematics. LEVEL OF EVIDENCE: IV.


Assuntos
Artroplastia do Joelho/métodos , Patela/cirurgia , Articulação Patelofemoral/fisiopatologia , Idoso , Fenômenos Biomecânicos , Humanos , Pessoa de Meia-Idade , Patela/fisiopatologia , Articulação Patelofemoral/cirurgia , Síndrome da Dor Patelofemoral/etiologia , Síndrome da Dor Patelofemoral/prevenção & controle , Amplitude de Movimento Articular , Rotação
12.
Cells Tissues Organs ; 196(4): 325-38, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22653337

RESUMO

The use of growth differentiation factor 5 (GDF-5) in damaged tendons has been shown to improve tendon repair. It has been hypothesized that further improvements may be achieved when GDF-5 is used to promote cell proliferation and induce tenogenic differentiation in human bone marrow-derived mesenchymal stem cells (hMSCs). However, the optimal conditions required to produce these effects on hMSCs have not been demonstrated in previous studies. A study to determine cell proliferation and tenogenic differentiation in hMSCs exposed to different concentrations of GDF-5 (0, 5, 25, 50, 100 and 500 ng/ml) was thus conducted. No significant changes were observed in the cell proliferation rate in hMSCs treated at different concentrations of GDF-5. GDF-5 appeared to induce tenogenic differentiation at 100 ng/ml, as reflected by (1) a significant increase in total collagen expression, similar to that of the primary native human tenocyte culture; (2) a significant upregulation in candidate tenogenic marker gene expression, i.e. scleraxis, tenascin-C and type-I collagen; (3) the ratio of type-I collagen to type-III collagen expression was elevated to levels similar to that of human tenocyte cultures, and (4) a significant downregulation of the non-tenogenic marker genes runt-related transcription factor 2 and sex determining region Y (SRY)-box 9 at day 7 of GDF-5 induction, further excluding hMSC differentiation into other lineages. In conclusion, GDF-5 does not alter the proliferation rates of hMSCs, but, instead, induces an optimal tenogenic differentiation response at 100 ng/ml.


Assuntos
Fator 5 de Diferenciação de Crescimento/farmacologia , Células-Tronco Mesenquimais/citologia , Células-Tronco Mesenquimais/efeitos dos fármacos , Adulto , Idoso , Diferenciação Celular/efeitos dos fármacos , Proliferação de Células/efeitos dos fármacos , Subunidade alfa 1 de Fator de Ligação ao Core/genética , Feminino , Expressão Gênica , Humanos , Masculino , Células-Tronco Mesenquimais/fisiologia , Pessoa de Meia-Idade , Engenharia Tecidual , Adulto Jovem
13.
Knee Surg Sports Traumatol Arthrosc ; 20(7): 1349-56, 2012 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-22186922

RESUMO

PURPOSE: Total knee arthroplasty (TKA) is a procedure with function dependent upon correct tensioning of the soft-tissue constraints. The purpose of this study was to examine the length-change behaviour of the collateral ligaments during knee flexion-extension before and after TKA. The influence of differing degrees of internal-external rotation of the femoral component on slackening/tightening of the collateral ligaments during knee flexion was to be studied. METHODS: The length-change patterns of the collateral ligaments were measured in eight intact knees in vitro: sutures were passed along the ligaments and attached to displacement transducers. Measurements were repeated after TKA with the femoral component in neutral rotation, then with 5° internal and 5° external rotation. RESULTS: Both the MCL and LCL slackened during knee flexion from 0° to 110° flexion, at all stages of the experiment. In the native knee, the MCL slackened 2 mm, whilst the LCL slackened 7 mm. The MCL slackened a further 3 mm and the LCL a further 4 mm during flexion post-TKA. A 5° external rotation of the femoral component slackened the MCL 2 mm more and tightened the LCL by 2 mm. The opposite effects resulted from 5° internal rotation. CONCLUSIONS: The collateral ligaments slackened more than normal following TKA, and these length changes were increased by femoral component rotation. External rotation of the femoral component to address patellar tracking may slacken the MCL and thus lead to valgus instability in the flexed knee.


Assuntos
Artroplastia do Joelho , Ligamentos Colaterais/anatomia & histologia , Ligamentos Colaterais/fisiologia , Articulação do Joelho/fisiologia , Amplitude de Movimento Articular/fisiologia , Idoso , Idoso de 80 Anos ou mais , Humanos , Pessoa de Meia-Idade , Rotação
14.
Am J Sports Med ; 39(2): 279-88, 2011 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-21239692

RESUMO

BACKGROUND: Although both anatomic double-bundle and single-bundle anterior cruciate ligament reconstruction procedures are in use, it remains controversial whether the anatomic double-bundle procedure is biomechanically superior. HYPOTHESIS: The anatomic double-bundle procedure would be better than both laterally placed anatomic and nonanatomic transtibial single-bundle procedures at restoring to normal the tibial anterior translation, internal rotation, and pivot-shift instability. It was also hypothesized that tibial internal rotation would be closer to normal after laterally placed anatomic single-bundle reconstruction than after the nonanatomic reconstruction. STUDY DESIGN: Controlled laboratory study. METHODS: Eight cadaveric knees were mounted in a 6 degrees of freedom rig and tested using the following loading conditions: 90-N anterior and posterior tibial forces, 5-N·m internal and external tibial rotation torques, and a simulated pivot-shift test. Tibiofemoral kinematics during the flexion-extension cycle were recorded with an optical tracking system for (1) intact, (2) anterior cruciate ligament-deficient knee, (3) anatomic double-bundle reconstruction, (4) nonanatomic single-bundle reconstruction, and (5) laterally placed single-bundle reconstruction. RESULTS: Rotational laxity with internal tibial torque and anterior laxity in the simulated pivot shift were significantly less in the double-bundle reconstruction and laterally placed single-bundle reconstruction compared with the nonanatomic single-bundle reconstruction. There were no significant differences between the 3 procedures when anterior and posterior tibial translation forces and external rotation torques were applied. In addition, there were no significant differences between the double-bundle reconstruction and laterally placed single-bundle reconstruction. CONCLUSION: The postoperative rotational and pivot-shift laxity after anatomic double-bundle anterior cruciate ligament reconstruction was significantly better than that after nonanatomic single-bundle reconstruction. However, there were no significant differences between the double-bundle reconstruction and laterally placed single-bundle reconstruction. CLINICAL RELEVANCE: This work suggests that a single-bundle reconstruction may be better able to control both knee laxity and pivot-shift instability if the femoral tunnel is moved to a more lateral position and that then the double-bundle reconstruction may not offer significant further advantages.


Assuntos
Ligamento Cruzado Anterior/cirurgia , Transferência Tendinosa/métodos , Idoso , Fenômenos Biomecânicos , Cadáver , Humanos , Instabilidade Articular/cirurgia , Articulação do Joelho/cirurgia , Pessoa de Meia-Idade , Recuperação de Função Fisiológica/fisiologia , Estresse Mecânico , Torque
15.
Am J Sports Med ; 38(7): 1349-58, 2010 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-20423987

RESUMO

BACKGROUND: Several trials have compared the clinical results between anatomic double-bundle and single-bundle anterior cruciate ligament reconstruction procedures. However, it remains controversial whether the anatomic double-bundle procedure is superior to the single-bundle procedure. HYPOTHESIS: The anatomic double-bundle procedure will be better than the single-bundle procedure at resisting anterior laxity, internal rotation laxity, and pivot-shift instability. STUDY DESIGN: Controlled laboratory study. METHODS: Eight cadaveric knees were tested in a 6 degrees of freedom rig using the following loading conditions: 90-N anterior tibialforce, 5-N.m internal and external tibial torques, and a simulated pivot-shift test. Tibiofemoral kinematics during the flexion-extension cycle were recorded with an optical tracking system for (1) intact, (2) anterior cruciate ligament-deficient knee, (3) anatomic double-bundle reconstruction, and (4) single-bundle reconstruction placed at 11 o'clock in the intercondylar notch. RESULTS: There were significant reductions of anterior laxity of 3.5 mm at 20 degrees of flexion, internal rotational laxity of 2.5 degrees at 20 degrees of flexion, and anterior translations (2 mm) and internal rotations (5 degrees ) in the simulated pivot-shift test in the double-bundle reconstruction com-pared with the single-bundle reconstruction. There were no significant differences between the 2 procedures for external rotation laxity. CONCLUSION: The postoperative anterior translation and internal rotation stability after anatomic double-bundle anterior cruciate ligament reconstruction were significantly better than after single-bundle reconstruction, in both static tests and the pivot shift. CLINICAL RELEVANCE: Unlike previous laboratory studies, this work used clinical arthroscopic methods for anterior cruciate ligament reconstruction, and found that the anatomic reconstruction was superior to a single graft placed at 11 o'clock.


Assuntos
Ligamento Cruzado Anterior/cirurgia , Artroscopia/métodos , Instabilidade Articular/fisiopatologia , Articulação do Joelho/fisiopatologia , Procedimentos Ortopédicos , Procedimentos de Cirurgia Plástica , Tendões/transplante , Tíbia/cirurgia , Adulto , Idoso , Fenômenos Biomecânicos , Humanos , Instabilidade Articular/cirurgia , Articulação do Joelho/cirurgia , Pessoa de Meia-Idade
16.
J Orthop Res ; 28(9): 1136-41, 2010 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-20217838

RESUMO

Malrotation of the femoral component may cause patellofemoral complications after total knee replacement (TKR). We hypothesized that femoral component malrotation would cause excessive lengthening of the retinacula. Retinacular length changes were measured by threading fine sutures along them and attaching these to the patella and to displacement transducers. The knee post-TKR was flexed-extended while the quadriceps were tensed, then the measurements repeated after rotating the femoral component 5 degrees internally and then 5 degrees externally. Internal rotation shortened the medial patellofemoral ligament (MPFL) significantly from 100 degrees to 0 degrees extension. External rotation lengthened the MPFL significantly from 90 degrees to 0 degrees extension. The transverse fibers of the lateral retinaculum showed no significant differences. The MPFL attaches directly from bone to bone, so it was lengthened directly by movement of the trochlea and patella, whereas the deep transverse fibers of the lateral retinaculum attach to the mobile iliotibial tract, so they were not lengthened directly.


Assuntos
Fêmur/fisiologia , Articulação do Joelho/fisiologia , Patela/fisiologia , Ligamento Patelar/fisiologia , Articulação Patelofemoral/fisiologia , Idoso , Idoso de 80 Anos ou mais , Artroplastia do Joelho , Humanos , Contração Isométrica/fisiologia , Prótese do Joelho , Pessoa de Meia-Idade , Músculo Quadríceps/fisiologia , Amplitude de Movimento Articular/fisiologia , Bancos de Tecidos
17.
J Orthop Res ; 28(5): 589-94, 2010 May.
Artigo em Inglês | MEDLINE | ID: mdl-19950364

RESUMO

Differing descriptions of patellar motion relative to the femur have resulted from previous studies. We hypothesized that patellar kinematics would correlate to the trochlear geometry and that differing descriptions could be reconciled by accounting for differing alignments of measurement axes. Seven normal fresh-frozen knees were CT scanned, and their kinematics with quadriceps loading was measured by an optical tracker system. Kinematics was calculated in relation to the femoral epicondylar, anatomic, and mechanical axes. A novel trochlear axis was defined, between the centers of spheres best fitted to the medial and lateral trochlear articular surfaces. The path of the center of the patella was circular and uniplanar (root-mean-square error 0.3 mm) above 16+/-3 degrees (mean+/-SD) knee flexion. In the coronal plane, this circle was aligned 6+/-2 degrees from the femoral anatomical axis, close to the mechanical axis alignment. It was 91+/-3 degrees from the epicondylar axis, and 88+/-3 degrees from the trochlear axis. In the transverse plane it was 91+/-3 degrees and 88+/-3 degrees from the epicondylar and trochlear axes, respectively. Manipulation of the data to different axis alignments showed that differing previously published data could be reconciled. The circular path of patellar motion around the trochlea, aligned with the mechanical axis of the leg, is easily visualized and understood.


Assuntos
Fêmur/fisiologia , Articulação do Joelho/fisiologia , Movimento/fisiologia , Patela/fisiologia , Amplitude de Movimento Articular/fisiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Fenômenos Biomecânicos , Cadáver , Fêmur/diagnóstico por imagem , Humanos , Articulação do Joelho/diagnóstico por imagem , Pessoa de Meia-Idade , Patela/diagnóstico por imagem , Rotação , Tíbia/fisiologia , Tomografia Computadorizada por Raios X
18.
Clin Orthop Relat Res ; 468(3): 782-8, 2010 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-19915941

RESUMO

BACKGROUND: In the natural and prosthetic knees the position, shape, and orientation of the trochlea groove are three of the key determinants of function and dysfunction, yet the rules governing these three features remain elusive. QUESTIONS/PURPOSE: The aim was to define the three-dimensional geometry of the femoral trochlea and its relation to the tibiofemoral joint in terms of angles and distances. METHODS: Forty CT scans of femurs of healthy patients were analyzed using custom-designed imaging software. After aligning the femur using various axes, the locations and orientations of the groove and the trochlear axis were examined in relation to the conventional axes of the femur. RESULTS: The trochlear groove was circular and positioned laterally in relation to the mechanical, anatomic, and transcondylar axes of the femur; it was not aligned with any of these axes. We have defined the trochlear axis as a line joining the centers of two spheres fitted to the trochlear surfaces lateral and medial to the trochlear groove. When viewed after aligning the femur to this new axis, the trochlear groove appeared more linear than when other methods of orientation were used. CONCLUSIONS: Our study shows the importance of reliable femoral orientation when reporting the shape of the trochlear groove.


Assuntos
Fêmur/anatomia & histologia , Articulação do Joelho/anatomia & histologia , Patela/anatomia & histologia , Tíbia/anatomia & histologia , Fêmur/diagnóstico por imagem , Humanos , Articulação do Joelho/diagnóstico por imagem , Articulação do Joelho/fisiologia , Pessoa de Meia-Idade , Patela/diagnóstico por imagem , Radiografia , Tíbia/diagnóstico por imagem
19.
J Arthroplasty ; 24(8): 1200-4, 2009 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19682839

RESUMO

We carried out a prospective study of 47 Exeter (Stryker Inc, Warsaw, Ind) small stem total hip arthroplasty in 42 patients with an average age of 58 years and a mean follow-up of 8.5 years. The Oxford hip score improved from a preoperative mean of 47 to 17 at last follow-up. More than 87% patients had excellent or good Harris hip scores, and 90% were able to walk with little or no pain. Stem subsidence within the cement mantle was observed in 26% of cases, and none showed evidence of aseptic loosening or implant failure. Two stems were removed due to infection. The survival rate of this implant was 95.7% at 10 years. This first series of Exeter small stem showed excellent medium-term results, comparable to its larger counterparts.


Assuntos
Artroplastia de Quadril , Articulação do Quadril/cirurgia , Prótese de Quadril , Artropatias/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Povo Asiático , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
20.
J Biomech ; 42(14): 2323-9, 2009 Oct 16.
Artigo em Inglês | MEDLINE | ID: mdl-19647256

RESUMO

UNLABELLED: Although lateral retinacular releases are not uncommon, there is very little scientific knowledge about the properties of these tissues, on which to base a rationale for the surgery. We hypothesised that we could identify specific tissue bands and measure their structural properties. Eight fresh-frozen knees were dissected, and the lateral soft tissues prepared into three distinct structures: a broad tissue band linking the iliotibial band (ITB) to the patella, and two capsular ligaments: patellofemoral and patellomeniscal. These were individually tensile tested to failure by gripping the patella in a vice jaw and the soft tissues in a freezing clamp. RESULTS: the ITB-patellar band was strongest, at a mean of 582N, and stiffest, at 97 N/mm. The patellofemoral ligament failed at 172 N with 16 N/mm stiffness; the patellomeniscal ligament failed at 85 N, with 13N/mm stiffness. These structural properties suggest that most of the load in-vivo is transmitted to the patella by the transverse fibres that originate from the ITB.


Assuntos
Cápsula Articular/fisiologia , Articulação do Joelho/fisiologia , Modelos Biológicos , Ligamento Patelar/fisiologia , Idoso , Simulação por Computador , Módulo de Elasticidade/fisiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Resistência à Tração
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