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1.
Med Image Anal ; 99: 103320, 2024 Sep 02.
Artigo em Inglês | MEDLINE | ID: mdl-39244796

RESUMO

The potential and promise of deep learning systems to provide an independent assessment and relieve radiologists' burden in screening mammography have been recognized in several studies. However, the low cancer prevalence, the need to process high-resolution images, and the need to combine information from multiple views and scales still pose technical challenges. Multi-view architectures that combine information from the four mammographic views to produce an exam-level classification score are a promising approach to the automated processing of screening mammography. However, training such architectures from exam-level labels, without relying on pixel-level supervision, requires very large datasets and may result in suboptimal accuracy. Emerging architectures such as Visual Transformers (ViT) and graph-based architectures can potentially integrate ipsi-lateral and contra-lateral breast views better than traditional convolutional neural networks, thanks to their stronger ability of modeling long-range dependencies. In this paper, we extensively evaluate novel transformer-based and graph-based architectures against state-of-the-art multi-view convolutional neural networks, trained in a weakly-supervised setting on a middle-scale dataset, both in terms of performance and interpretability. Extensive experiments on the CSAW dataset suggest that, while transformer-based architecture outperform other architectures, different inductive biases lead to complementary strengths and weaknesses, as each architecture is sensitive to different signs and mammographic features. Hence, an ensemble of different architectures should be preferred over a winner-takes-all approach to achieve more accurate and robust results. Overall, the findings highlight the potential of a wide range of multi-view architectures for breast cancer classification, even in datasets of relatively modest size, although the detection of small lesions remains challenging without pixel-wise supervision or ad-hoc networks.

2.
Ig Sanita Pubbl ; 63(3): 305-17, 2007.
Artigo em Italiano | MEDLINE | ID: mdl-17786172

RESUMO

The National Health Plan 2006-2008 underlines the need to overcome the differences that exist in the health care services of the Italian regions. Because the health care systems are organised differently on the territory, the Regions provide different answers to the health needs of their residents. Therefore, the purpose of this document is that of analysing the characteristics of the Italian public health care system in 2003. While in the first part, the health system is described region by region, in the second part, a cluster analysis is used to describe the local health authorities. The results show that while both the first and second level assistance have become stronger, the centrality of the hospital system has decreased, even though it still occupies a dominant position.


Assuntos
Atenção à Saúde , Saúde Pública , Serviços de Saúde , Humanos
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