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1.
Vestn Otorinolaringol ; 88(6): 107-110, 2023.
Artigo em Russo | MEDLINE | ID: mdl-38153902

RESUMO

We present to your attention a case of mature teratoma of the pharynx and nasal cavity in a newborn, which caused severe obstruction of the upper respiratory tract and required emergency action. The article describes the diagnostic algorithm, the choice of optimal treatment tactics, which allowed rehabilitate the child in infancy.


Assuntos
Cavidade Nasal , Teratoma , Recém-Nascido , Criança , Humanos , Cavidade Nasal/diagnóstico por imagem , Cavidade Nasal/cirurgia , Faringe , Teratoma/diagnóstico , Teratoma/cirurgia
2.
Arkh Patol ; 79(3): 34-41, 2017.
Artigo em Russo | MEDLINE | ID: mdl-28631714

RESUMO

Extrarenal extracranial rhabdoid tumor (EERT) is a rare malignant pediatric tumor characterized by extremely aggressive behavior, rapid metastatic spread, low survival rates, and no targeted therapy. The morphological diagnosis of classical cases of EERT is not difficult and it is based on its characteristic histologic pattern and immunohistochemical findings in a relatively short time, which allows one to immediately initiate therapy. The paper describes two cases of ERRT in the complete absence of classical rhabdoid morphology, as revealed by light microscopy when the material was primarily assessed. The final diagnostic search could establish a diagnosis of EERT in both cases on the basis of immunohistochemical findings.


Assuntos
Neoplasias de Cabeça e Pescoço/patologia , Neoplasias Hepáticas/patologia , Neoplasias do Mediastino/patologia , Tumor Rabdoide/patologia , Criança , Feminino , Humanos , Imuno-Histoquímica , Lactente , Masculino
3.
Arkh Patol ; 75(5): 36-42, 2013.
Artigo em Russo | MEDLINE | ID: mdl-24341231

RESUMO

The paper describes 6 cases of atypical teratoid/rhabdoid tumors (ATRT) in the complete absence of classical rhabdoid elements isolated from 25 INI1-negative central nervous system tumors investigated in the period 2006 to the present time. Analysis of the specific features of the histological structure of INI1-negative tumors could identify a few histological types of ATRT according to the conventionally standardized criteria for diagnostic search.


Assuntos
Neoplasias do Sistema Nervoso Central/diagnóstico , Neoplasias do Sistema Nervoso Central/patologia , Tumor Rabdoide/diagnóstico , Teratoma/diagnóstico , Adolescente , Neoplasias do Sistema Nervoso Central/genética , Pré-Escolar , Proteínas Cromossômicas não Histona/genética , Proteínas de Ligação a DNA/genética , Feminino , Regulação Neoplásica da Expressão Gênica , Humanos , Hibridização in Situ Fluorescente , Lactente , Masculino , Mutação , Tumor Rabdoide/genética , Tumor Rabdoide/patologia , Proteína SMARCB1 , Teratoma/genética , Teratoma/patologia , Fatores de Transcrição/genética
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