RESUMO
We present to your attention a case of mature teratoma of the pharynx and nasal cavity in a newborn, which caused severe obstruction of the upper respiratory tract and required emergency action. The article describes the diagnostic algorithm, the choice of optimal treatment tactics, which allowed rehabilitate the child in infancy.
Assuntos
Cavidade Nasal , Teratoma , Recém-Nascido , Criança , Humanos , Cavidade Nasal/diagnóstico por imagem , Cavidade Nasal/cirurgia , Faringe , Teratoma/diagnóstico , Teratoma/cirurgiaRESUMO
Extrarenal extracranial rhabdoid tumor (EERT) is a rare malignant pediatric tumor characterized by extremely aggressive behavior, rapid metastatic spread, low survival rates, and no targeted therapy. The morphological diagnosis of classical cases of EERT is not difficult and it is based on its characteristic histologic pattern and immunohistochemical findings in a relatively short time, which allows one to immediately initiate therapy. The paper describes two cases of ERRT in the complete absence of classical rhabdoid morphology, as revealed by light microscopy when the material was primarily assessed. The final diagnostic search could establish a diagnosis of EERT in both cases on the basis of immunohistochemical findings.
Assuntos
Neoplasias de Cabeça e Pescoço/patologia , Neoplasias Hepáticas/patologia , Neoplasias do Mediastino/patologia , Tumor Rabdoide/patologia , Criança , Feminino , Humanos , Imuno-Histoquímica , Lactente , MasculinoRESUMO
The paper describes 6 cases of atypical teratoid/rhabdoid tumors (ATRT) in the complete absence of classical rhabdoid elements isolated from 25 INI1-negative central nervous system tumors investigated in the period 2006 to the present time. Analysis of the specific features of the histological structure of INI1-negative tumors could identify a few histological types of ATRT according to the conventionally standardized criteria for diagnostic search.