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1.
Analyst ; 146(20): 6333, 2021 Oct 11.
Artigo em Inglês | MEDLINE | ID: mdl-34633396

RESUMO

Correction for 'Crystalline sponge X-ray analysis coupled with supercritical fluid chromatography: a novel analytical platform for the rapid separation, isolation, and characterization of analytes' by Yoshimasa Taniguchi et al., Analyst, 2021, 146, 5230-5235, DOI: 10.1039/D1AN00948F.

2.
Analyst ; 146(17): 5230-5235, 2021 Sep 07.
Artigo em Inglês | MEDLINE | ID: mdl-34373868

RESUMO

Crystalline sponge (CS) based X-ray diffraction (XRD) analysis allows for the observation of the structure of an analyte, including its absolute configuration. Herein we report a powerful analytical platform for the separation, isolation, and structural elucidation of a target analyte in a seamless way by coupling supercritical fluid chromatography (SFC) with CS-based XRD analysis (SFC-CSXRD). The efficacy of this methodology is demonstrated by the rapid characterization of regio- and stereoisomers using three types of CSs with differing tolerances to the solvents used in SFC and guest-soaking.


Assuntos
Cromatografia com Fluido Supercrítico , Cristalografia por Raios X , Solventes , Estereoisomerismo , Raios X
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