Presentation, clinical course and complications in trauma patients with concomitant COVID-19 infection.

BACKGROUND: This study investigated the impact of COVID-19 infection on hospitalized trauma patients. METHODS: A retrospective review of hospitalized trauma patients at a level I trauma center was performed from March-December 2020. Data pertaining to patient demographics, presentation and hospital course was compared between COVID positive and negative trauma patients. RESULTS: There were 4,912 patients and 179 (3.64%) were COVID-19 positive. Demographics and clinical presentation did not differ significantly between those with and without concomitant COVID-19. However, COVID positive trauma patients had higher rates of acute kidney injury (p = 0.016), sepsis (p = 0.016), unplanned intubation (p = 0.002) and unplanned return to the ICU (p = 0.01). The COVID positive cohort also had longer hospital stays (p < 0.01) with no significant difference in mortality. CONCLUSIONS: In the setting of an ongoing pandemic, awareness of the complications COVID positive trauma patients are predisposed to is important for providers.

Radiographic Outcomes and Complications of Delayed Fixation of Distal Radius Fractures.

BACKGROUND: Surgeons are sometimes presented with patients with distal radius fractures who present in a delayed fashion or lose reduction after several weeks of attempted closed management. There are limited studies on delayed surgical treatment of distal radius fractures to assist providers in decision-making. METHODS: We conducted a matched cohort study to compare radiographic outcomes and complications for patients with a distal radius fracture treated with delayed (3-5 weeks) or early (0-2 weeks) surgical fixation. Patients ages 18+ who underwent open reduction and internal fixation of distal radius fractures by a volar approach at 2 Level I trauma centers between 2003 and 2015 were eligible. We measured radiographic outcomes and reviewed medical records to determine operative approach and complications. RESULTS: There were 25 cases and 50 controls matched for age (18-87), sex, and AO fracture type. The delayed group had surgery at a mean of 24.8 days from injury and the early group at 5.6 days. There was no statistically significant difference between the delayed and early cohorts in radiographic parameters on injury x-rays, in improvement in radiographic parameters on first postoperative x-rays, or in maintenance of radiographic parameters at union. CONCLUSION: We did not find significant differences in radiographic outcomes or complication rates between patients with delayed versus early surgical treatment for distal radius fracture. Providers treating patients with late presentation or late displacement have the option of surgical fixation beyond the first few weeks after injury. LEVEL OF EVIDENCE: III (Retrospective matched cohort study).

Patient Perceptions and Preferences for Osteoporosis Treatment.

PURPOSE: Despite the high prevalence, morbidity, and treatment costs for osteoporosis-related fractures, studies have shown that patients infrequently receive the recommended treatment for low bone density (LBD). This study investigated patient perceptions about evaluation, management, and willingness to pursue osteoporosis treatment to further elucidate potential barriers to LBD treatment. METHODS: A survey was prospectively administered to patients over 50 years old addressing patient history of fragility fractures and osteoporosis evaluation and treatment, medication administration preferences, and willingness to start a new medication to treat or prevent future fragility fractures. RESULTS: Three hundred twenty-five patients completed surveys (63.1% women, 36.9% men; mean age, 64.1 years). Patients reported the following: 50.8% had taken supplements or medication for LBD. Patients who had never taken LBD prescription medications were asked about their willingness to take these medications if physician-recommended. The mean response on a 0 to 10 scale was 7.3 ± 3.2, which was not significantly different between fracture or bone density subgroups. Several barriers to taking LBD medications were identified: 85.7% said no medical provider had prescribed them; 14.0% stated they already took too many medications; 10.4% were afraid of potential side effects; 4.3% had conflicting provider recommendations; and 1.8% cited financial concerns. CONCLUSIONS: Patients held a favorable opinion on taking LBD medications when prescribed. Although 29.8% of patients had an abnormal dual-energy x-ray absorptiometry (DEXA) result, 85.7% of all patients reported that no medical provider had prescribed LBD medications. A sizeable gap remains between current practice and optimal osteoporosis education and management. CLINICAL RELEVANCE: Despite the large reported and increasing prevalence of osteoporosis in patients with upper extremity fragility fractures, the rate of treatment for LBD remains suboptimal.

Midterm Clinical and Radiographic Follow-Up of Pyrolytic Carbon PIP Arthroplasty.

PURPOSE: The use of pyrolytic carbon arthroplasty (PCA) for the proximal interphalangeal (PIP) joint is controversial. The goal of this study was to evaluate the clinical and radiographic midterm outcomes of PIP joint PCA. METHODS: Patients were contacted after PIP PCA at 6.4 ± 1.9 years (mean ± SD). Evaluation included grip and pinch strength and digital range of motion (ROM). Radiographs and patient reported outcomes surveys were obtained. RESULTS: This study included 29 PIP joint PCA devices implanted in 23 hands among 19 patients. Seven devices underwent subsequent procedures. Three were removed and revised to silicone implants because of 2 dislocations and one implant migration. One underwent revision to a larger distal component. Three required soft tissue surgical revisions in which the implant was retained (one flexor digitorum superficialis tenodesis and 2 capsulectomies). At the time of latest follow-up, there was 86.2% original implant survivorship. The most recent radiographic review of the remaining 26 implants revealed 2 swan neck deformities and 2 implant migrations. Postoperative grip (38.4 ± 16.8 lb) and pinch (13.8 ± 2.7 lb) strength were 92% and 91%, respectively, of nonsurgical grip and pinch strength. Final mean ROM (range) for the metacarpophalangeal joint was 82.1° (60° to 100°) and for the PIP joint was 60.6° (20° to 110°). Mean outcome scores were: visual analog scale, 1.6 (± 2.4), Michigan Hand Questionnaire, 71.6 (± 17.6), and Disabilities of the Arm, Shoulder, and Hand, 24.7 (± 14.5). CONCLUSIONS: Midterm follow-up (mean, 6.4 years) for 29 PCA implants in 19 patients revealed a surgical revision rate of 24.1%. Of the 29 implants, 13.8% were removed at a mean of 4.6 years (range, 1.3-7.9 years). Strength, ROM, and pain relief were all satisfactory. TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic IV.

Evaluating the Online Presence of Orthopaedic Surgeons.

PURPOSE: The objective of this study was to evaluate and characterize the professional and educational information provided online by US orthopaedic surgeons. METHODS: The American Academy of Orthopaedic Surgeons (AAOS) membership directory was used to randomly select 1% of physicians from each state. Name, sex, state, and date of membership were recorded from the AAOS online public membership directory. A Google search was conducted for each member of this cohort. Specific data gathered from each website included practice type, physician subspecialty, website focus (commercial or educational), and the quality of patient education presented were evaluated. RESULTS: The cohort consisted of 246 orthopaedic surgeons, including 93.1% men and 6.9% women. The AAOS membership duration was less than 10 years for 48.0% of surgeons, 11 to 20 years for 28.9% of surgeons, and greater than 20 years for 23.2% of surgeons. At least one online profile was found for 94.3% of orthopaedic surgeons. Most surgeons, 66.8%, were identified as belonging to a group or solo private practice, although nearly half (48.7%) of all surgeons were also based out of a hospital. Most website profiles, 62.5%, were found to have an intermediate level of educational content, whereas 18.1% of website profiles did not provide any. DISCUSSION: The clear majority of US-based orthopaedic surgeons have a professional presence online. Focus on social media or educational content differs regionally, but not based on years in practice. LEVEL OF EVIDENCE: Level V, prognostic.

Range of Motion Measurements of the Fingers Via Smartphone Photography.

Background: Range of motion (ROM) measurements of the fingers are frequently obtained during hand physical examinations. While traditionally measured by manual goniometry, smartphone photography introduces an alternative method of ROM measurement that also has potential telemedicine applications. The purpose of this study was to evaluate the reliability of smartphone photography measurements as an alternative to traditional goniometry, using the patient with Dupuytren disease as a model. Methods: Patients with a confirmed Dupuytren contracture were prospectively enrolled in this study. Range of motion measurements of the affected joints were obtained prior to any invasive treatments. Two sets of photographs were taken by both a clinical staff member and a nonclinical individual unaffiliated with the study. Both sets of photos were analyzed for degree of contracture via software analysis and compared against traditional goniometer measurements. Results: The study prospectively enrolled 50 consecutive patients with Dupuytren disease, comprising 123 affected joints. The mean contractures of all affected joints as measured by manual goniometry, trained photograph goniometry, and untrained photograph goniometry were 38.5, 35.3, and 35.5, respectively. The mean difference in contracture measurement was 3.2° between manual and trained photograph goniometry and 3.0° between manual and untrained photograph goniometry. There was no statistically significant difference between trained and untrained photo set measurements. Photograph measurements between separate raters demonstrated high consistency (intraclass correlation coefficient = 0.92). Conclusions: Smartphone photography provides contracture measurements equivalent to the accepted error of a finger goniometer (3.2° compared with 5°). The accuracy of smartphone photography in measuring contractures offers potential telemedicine applications for both clinical and research needs.

Median Nerve Ultrasonography Measurements Correlate With Electrodiagnostic Carpal Tunnel Syndrome Severity.

INTRODUCTION: The purpose of this study was to assess whether median nerve ultrasonography (US) measurements correlate with the severity scale of electrodiagnostic studies (EDS) of carpal tunnel syndrome (CTS). METHODS: A retrospective review was conducted of patients aged ≥18 years who underwent both median nerve US and EDS. US measurements of the median nerve cross-sectional area at the distal wrist crease and forearm were used to calculate the median nerve wrist-to-forearm ratio. EDS severity was classified according to guidelines from the American Association of Electrodiagnostic Medicine. RESULTS: A total of 112 wrists (n = 112) in 78 consecutive patients with a mean age of 59 (range, 26 to 88) years were included. Increased cross-sectional area at the distal wrist crease and wrist-to-forearm ratio were significantly correlated with increased EDS severity (P < 0.0001). DISCUSSION: Median nerve US measurements not only distinguished between normal and abnormal EDS but also correlated with the category of EDS severity. LEVEL OF EVIDENCE: Diagnostic III.

Implementing a Postoperative Opioid-Prescribing Protocol Significantly Reduces the Total Morphine Milligram Equivalents Prescribed.

BACKGROUND: Opioid-prescribing patterns have been implicated as a contributing factor to the opioid epidemic, yet few evidence-based guidelines exist to assist health-care providers in assessing and possibly modifying their prescribing practices. METHODS: Five orthopaedic hand surgeons at a level-I trauma center developed a postoperative prescribing guideline for 25 common hand and upper-extremity outpatient procedures, which were delineated into 5 tiers. Postoperative opioid prescriptions in a 3-month period after implementation of the protocol were compared with those from a 3-month period before implementation of the protocol. RESULTS: There were 231 patients in the pre-implementation group and 287 patients in the post-implementation group. Each individual opioid protocol tier showed a significant decrease in the mean morphine milligram equivalents (MME) prescribed, ranging from a minimum decrease of 97.8% to a maximum decrease of 176.0%. After implementation, adherence to protocol was achieved in 55.1% of patients; the MME amounts prescribed were below protocol for 28.6% and above for 16.4%. The number of additional opioid prescriptions in the 1-month postoperative period was significantly less in the post-implementation group than in the pre-implementation group (p < 0.001). The total number of pills prescribed was reduced by a theoretical equivalent of over three thousand 5-mg oxycodone pills for the 287 patients in the 3-month period. CONCLUSIONS: By utilizing a simple consensus protocol, we have demonstrated success diminishing the number of opioids prescribed without leading to an increase in the number of secondary prescriptions written by our providers. These findings are encouraging and suggest that fewer opioids were left in the possession of patients, leaving fewer pills vulnerable to misuse, abuse, and diversion.

Extending a Hand: Increasing Diversity at the American Society for Surgery of the Hand.

PURPOSE: This study aimed to assess diversity among American Society for Surgery of the Hand (ASSH) members, ASSH annual meeting attendees, and ASSH annual meeting presenters from 2010 to 2016. We hypothesized that over the past 7 years, the ASSH has seen an increase in diversity in its membership, annual meeting attendance, and presenters. METHODS: Detailed demographic data for membership, annual meeting attendance, and annual meeting presenters were obtained from the ASSH for a 7-year period (2010-2016). The proportion of women, underrepresented minorities (URM), and nationality of members, attendees, and presenters was compared over the 7 years to assess trends and differences. RESULTS: Membership in ASSH has increased 30.0% over the past 7 years. Whereas United States membership increased by 113 members annually, international membership increased by 53 members annually, reflecting a 136% total increase. The percentage of women and URM attending the annual meeting is higher than the that of women and URM members. There have been increases in the number of women, URM, and international members over this period. CONCLUSIONS: Over the study period, the ASSH membership has seen increases in women and URM representation. International membership has seen substantial growth. In addition, meeting attendance by international members has increased, particularly since implementation of the guest nation program. CLINICAL RELEVANCE: Women and URM make up an increasing percentage of ASSH members. International members and presenters have also increased. Although diversity has improved over the past several years, the ASSH should continue to efforts toward greater inclusion and representation.

Treatment Patterns, Outcomes, and Patient Satisfaction of Primary Epidermally Limited Nonmelanoma Skin Cancer.

BACKGROUND: Epidermally limited nonmelanoma skin cancer (ELNMSC) (superficial basal cell carcinoma [SBCC] and squamous cell carcinoma in situ [SCCIS]) is common. Data on outcomes and patient satisfaction are lacking. OBJECTIVE: To examine treatment efficacy and satisfaction in ELNMSC patients. PATIENTS AND METHODS: Retrospective cohort study of adults with primary SBCC or SCCIS. A 25% random subset completed a satisfaction questionnaire. RESULTS: Five hundred and fifty patients with 227 SBCC and 451 SCCIS were included; 329 tumors (49%) were treated with Mohs micrographic surgery (MMS) and 349 (51%) with non-MMS (imiquimod [n = 26], 5% 5-fluorouracil [n = 234], ingenol mebutate [n = 32], or cryotherapy [n = 57]). Five-year recurrence-free survival was high in both groups, with MMS having a small but statistically significant advantage (99% vs 95%, p = .004). More MMS patients were willing to undergo treatment again (97% vs 86%, p = .024). Dissatisfaction was mostly due to prolonged treatment course and pain associated with non-MMS treatments. CONCLUSION: Surgical and nonsurgical treatments for primary ELNMSC have low recurrence rates, though cure rate and patient satisfaction are higher with MMS. Treatment choice for epidermal NMSC may be guided through patient preferences regarding ability to comply with topical treatment, out-of-pocket costs, desire to treat surrounding field disease, and desire to avoid a surgical scar.

Needle-Free Jet Lidocaine Administration for Preinjection Anesthesia in Trigger Finger Injection: A Randomized Controlled Trial.

PURPOSE: To evaluate the efficacy of needle-free jet lidocaine (J-tip) administration for pain reduction in trigger finger corticosteroid injection compared with simultaneous lidocaine injection with corticosteroid. METHODS: A prospective randomized clinical trial was performed in which patients received either 0.25 mL of 2% lidocaine administered by J-tip just prior to 0.5 mL of corticosteroid injection by needle or 0.5 mL of 1% lidocaine and 0.5 mL of corticosteroid administered simultaneously through a needle for the treatment of trigger finger. Both the expected pain preinjection and the actual pain experienced postinjection were measured with a visual analog scale (VAS). Pain catastrophizing scale (PCS) scores were recorded before injection. RESULTS: The use of the J-tip demonstrated a lower mean actual pain, 3.3 VAS, compared with the control group, 4.6 VAS. Both study groups anticipated more pain than they actually experienced. The PCS did not correlate to pre- or post-injection scores. CONCLUSIONS: Needle-free jet administration of lidocaine reduces the pain associated with trigger finger injection. Patients anticipate more pain than they experience with trigger finger injection. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic I.

A quantitative systematic review of the efficacy of imiquimod monotherapy for lentigo maligna and an analysis of factors that affect tumor clearance.

BACKGROUND: The reported efficacy of imiquimod for lentigo maligna varies widely, without consensus on tumor or treatment factors that can impact tumor clearance. OBJECTIVE: We sought to provide a more precise estimate of clearance rates in patients with lentigo maligna who are treated with imiquimod and to analyze factors that can impact tumor clearance. METHODS: We performed a literature search for biopsy-proven lentigo maligna treated with imiquimod monotherapy, linked treatment and outcome data to individual tumors, calculated histologic and clinical clearance rates with 95% confidence intervals (CIs), and analyzed the impact of tumor and treatment factors on tumor clearance using logistic regression. RESULTS: Based on 347 tumors from 45 studies, histologic and clinical clearance rates were 76.2% (95% CI, 71.4-81.0%) and 78.3% (95% CI, 73.6-82.9%), respectively. The incidence of clinical recurrence was 2.3% (95% CI, 0.5-4.2%), with a mean follow-up of 34.2 ± 11.8 months. Treatment with >60 total applications, or with >5 applications per week was associated with a higher likelihood of histologic clearance (odds ratio, 8.4 [95% CI, 2.9-24.1] and odds ratio, 6.0 [95% CI, 2.4-14.7], respectively). LIMITATIONS: Our limitations included the accuracy and scope of published data, variable follow-up times, potential patient selection, and publication bias related to case series/cohort designs of previous studies. CONCLUSION: Imiquimod offers a 76% histologic and 78% clinical clearance rate for lentigo maligna. Both cumulative dose and treatment intensity affect tumor clearance.