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1.
Healthcare (Basel) ; 12(2)2024 Jan 16.
Artigo em Inglês | MEDLINE | ID: mdl-38255109

RESUMO

Breast cancer treatments can elicit negative kinesiological side effects concerning both the posture and functional status of breast cancer survivors. As our body is functionally organized in myofascial meridians, physical exercise practice should favor a whole-body approach rather than a local one. The aim of the study was to investigate and compare the effects of two whole-body disciplines, i.e., adapted Nordic Walking and myofascial exercise, on the flexibility and strength performances in BCS. One hundred and sixty breast cancer survivors were trained three times per week for 12 weeks through adapted Nordic Walking or myofascial exercise. Handgrip, sit and reach, back scratch, and single leg back bridge tests and body composition were assessed at the beginning and completion of the training period. Linear mixed models showed no significant changes in body composition, whereas flexibility (p < 0.001), strength (p < 0.001), and muscle quality index (p = 0.003) changed independently from the treatment. When data modification has been analyzed according to sub-sample membership, no significant differences have been observed. Age, radiation therapy, and chemotherapy seem to have independent effects on several investigated variables. Twelve weeks of adapted myofascial exercise and Nordic Walking led to significant changes in flexibility, strength, and muscle quality in breast cancer survivors, with no apparent superiority of one approach over the other.

2.
J Clin Med ; 12(14)2023 Jul 20.
Artigo em Inglês | MEDLINE | ID: mdl-37510910

RESUMO

BACKGROUND: Breast cancer (BC) and cardiovascular (CV) disease share many risk factors associated with worse outcomes, in terms of cancer relapse, CV events, and quality of life (QoL), that could be counteracted by physical exercise (PE). We aimed to assess the impact of a 12-week differential PE protocol on cardiometabolic profile, QoL, CV- and BC-related long-term outcomes, and physical activity (PA) in a cohort of BC survivors (BCS) not treated with chemotherapy. METHODS: 57 BCS participated in a 12-week PE protocol [aerobic exercise training (AET) or resistance exercise training (RET)]. Anthropometric and CV evaluation, health-related (HR)-QoL, daily PA, cortisol, and dehydroepiandrosterone sulfate (DHEA-S) levels were assessed before (T0) and after (T1) PE. We assessed BC and CV outcomes, HR-QoL, CV-QoL, and PA at the follow-up. RESULTS: RET improved waist circumference, DHEA-S, cortisol/DHEA-S, systolic and mean blood pressure, and ventricular/arterial coupling; AET ameliorated sagittal abdomen diameter and pulse wave velocity. Regarding HR-QoL, physical function improved only in AET group. At a mean 34 ± 3.6-month follow-up, we documented no significant differences in CV-QoL, HR-QoL, and PA or CV and BC outcomes. CONCLUSIONS: AET and RET determine specific, positive adaptations on many parameters strongly related to CV risk, CV and BC outcomes, and QoL, and should be included in any cardio-oncology rehabilitation program.

3.
Home Health Care Serv Q ; 41(3): 200-218, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35184693

RESUMO

In breast cancer survivors (BCS), the contemporaneous increase of sedentary time and reduction of physical activity (PA) requires early attention because it has negative consequences for their health. Aims of the study were to investigate: a) the correlations between PA, sedentarism, and health-related measures; b) the association between different patterns of daily activity and health-related outcomes. Two hundred and nineteen BCS (50.98 ± 6.28) were selected for this study. Psychological, anthropometric, endocrine, sleeping, and both daily sedentary time and PA variables were considered. Sedentarism and PA have opposite correlations with anthropometric variables, anxiety, depression, morning salivary cortisol, and sleeping characteristics. The first favors pathological values and the latter favors normal values. Regression tree analysis showed the impact of different daily sedentary time and PA combinations on the investigated variables and allowed the individualization of their optimal combination for health. Our results could be useful to healthcare providers and BCS.


Assuntos
Neoplasias da Mama , Sobreviventes de Câncer , Neoplasias da Mama/psicologia , Neoplasias da Mama/terapia , Exercício Físico/psicologia , Feminino , Nível de Saúde , Humanos , Inquéritos e Questionários
4.
Home Health Care Serv Q ; 41(1): 1-19, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34651554

RESUMO

The aim of the study was to compare the effects of weekly personal feedback, based on objectively measured physical activity, on daily sleep in breast cancer survivors (BCS) with those of an intervention that also included online supervised physical exercise sessions (OSPES). BCS benefiting from both personal feedback and OSPES (n = 24), from pre-lockdown (T0) to the first month (T1) of the national lockdown, experienced an increase in both total (p ≤ 0.001) and restorative (p ≤ 0.001) sleep time, inverting their trend from the first month of lockdown to its end (total sleeping time T1 vs. T2 0.01 ≤ p < .001, T1 vs. T3 p ≤ 0.001; restorative sleeping time T1 vs. T2 0.05 ≤ p < .01, T1 vs. T3 p ≤ 0.001). Supportive technology, together with the reception of weekly tailored advice and OSPES seems to improve both quality and quantity of sleep.


Assuntos
Neoplasias da Mama , COVID-19 , Sobreviventes de Câncer , Neoplasias da Mama/complicações , Neoplasias da Mama/terapia , Controle de Doenças Transmissíveis , Aconselhamento , Exercício Físico , Feminino , Monitores de Aptidão Física , Humanos , Itália , Sono
5.
J Funct Morphol Kinesiol ; 6(2)2021 Jun 09.
Artigo em Inglês | MEDLINE | ID: mdl-34207765

RESUMO

BACKGROUND: To prevent and fight the increase of daily sedentary time and to promote and stimulate the positive effects of physical activity and exercise on health, both traditional interventions and new strategies are important for breast cancer survivors (BCS). The research goal was to compare the effects of weekly personal feedback, based on objectively measured physical activity, on the trends of both daily sedentary time and on the physical activity of BCS (E- group) with those of an intervention also including online supervised physical exercise sessions (E+ group), during the Italy COVID-19 lockdown. METHODS: The Italian COVID-19 emergency allowed the possibility to also observe the effects of social and personal limitations. A total of 51 BCS were studied over an 18-week period and had an objective registration of day-to-day sedentary time, physical activity, and sleep. Both subsamples received weekly or fortnight personal feedback. Data were analysed considering four key periods, according to the COVID-19 emergency steps. RESULTS: Statistical analysis showed an additive effect for sedentary time and a multiplicative effect both for light-to vigorous and light-intensity physical activities. The E- group had a high overall sedentary time and a different trend of light-to vigorous and light-intensity physical activities, with a reduction from the 1st to the 2nd periods (national and personal restrictions), showing a significant rise just at the end of the national restrictions. CONCLUSIONS: The use of an activity tracker and its accompanying app, with the reception of weekly tailored advice and supervised online physical exercise sessions, can elicit proper physical activity recomposition in BCS in the COVID-19 era.

6.
Complement Ther Clin Pract ; 27: 19-26, 2017 May.
Artigo em Inglês | MEDLINE | ID: mdl-28438275

RESUMO

The aim of this study was to analyse the health status of breast cancer survivors and the effects of 12 weeks of aerobic training. Twenty-three breast cancer survivors (51.71 ± 3.17 years) and 23 healthy women (50.73 ± 2.97 years) were investigated for body composition, daily physical activity, quality of life, salivary cortisol, and DHEA-S. Breast cancer survivors were then aerobically trained for 12 weeks. Breast cancer survivors have a worse psychophysical health than healthy women. Aerobic training increased salivary DHEA-S, aerobic fitness, self-reported health, and nocturnal sleeping time and reduced salivary cortisol in breast cancer survivors. Salivary cortisol variation correlated with change of sleeping time and self-reported health. Salivary DHEA-S correlated with change of self-reported physical pain and general health as well. Breast cancer survivors can live in a situation of continuous distress, requiring a multidisciplinary approach. Twelve weeks of aerobic training improve the psychophysical health of breast cancer survivors.


Assuntos
Neoplasias da Mama , Exercício Físico , Neoplasias da Mama/fisiopatologia , Neoplasias da Mama/psicologia , Estudos de Casos e Controles , Exercício Físico/fisiologia , Exercício Físico/psicologia , Feminino , Humanos , Hidrocortisona/análise , Pessoa de Meia-Idade , Saliva/química , Inquéritos e Questionários , Sobreviventes/psicologia , Sobreviventes/estatística & dados numéricos
7.
J Cancer Educ ; 32(4): 734-739, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27085551

RESUMO

Beach activities and outdoor sports are risk factors for developing skin cancer. Skateboarding is among the most popular sports among adolescents. The aim was to analyse the sun exposure habits and sun protection practices of skaters, in comparison with corresponding sun exposure and protection practices on the beach. This cross-sectional study is based on health surveys carried out into sun exposure and protection practices among young skateboarders. The study population was composed of 102 skaters, of whom 84 (82.4 %) were male. Fifty-eight (56.8 %) of the participants reported having suffered at least one sunburn event the previous summer. Eighty-seven (91.6 %) said they practiced outdoor sports more than 90 days per year, while only six (6.1 %) spent this long at the beach. Forty-nine (52.1 %) practiced outdoor sports for 5 or more hours a day compared to 42 (43.3 %) who spent comparable periods at the beach. A long-sleeved shirt was worn more frequently during sports than at the beach. Keen skaters are a risk group for the development of skin cancer due to excessive sun exposure, high rates of sunburn and scant use of sun protection measures. Specific educational and behavioural interventions should be aimed at this risk group.


Assuntos
Comportamento do Adolescente/psicologia , Patinação/fisiologia , Queimadura Solar/prevenção & controle , Protetores Solares/uso terapêutico , Raios Ultravioleta/efeitos adversos , Adolescente , Estudos Transversais , Feminino , Inquéritos Epidemiológicos , Humanos , Masculino , Fatores de Risco , Patinação/tendências , Neoplasias Cutâneas/prevenção & controle , Espanha , Fatores de Tempo , Esportes Aquáticos
8.
J Cancer Educ ; 32(3): 596-603, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26781696

RESUMO

Adolescents are considered a risk group for the development of skin cancer in later life due to their high rates of sunburn. The aim of this study is to evaluate the association between attitudes to sun exposure and the sociodemographic characteristics of adolescents, their habits, practices and knowledge. As a secondary goal, we describe the magnitude and sign of the correlations between these attitudes. Cross-sectional study of adolescent students from 12 secondary schools in southern Spain, the subjects were asked to complete the 'Beach Questionnaire'. This instrument examines four dimensions of attitudes, with standardised scores of 0-100, related to the sun, sun tanning, sun protection and sun cream. The higher the score, the more positive the attitude. The study population was composed of 270 adolescents. The highest scores were obtained for attitudes towards sun protection practices (mean 66.2; SD 18.6) and towards sun tanning (mean 64.2; SD 21.1). The lowest scores were obtained for attitudes towards using sun cream (mean 50.1; SD 24.6). Significant differences were found for all four attitudes, with a positive sign for the relationship between the number of days of sun exposure and a higher score for attitudes towards sunbathing (27.3 points difference between response extremes) and for attitudes towards suntanning (20 points difference). Favourable attitudes towards sunbathing and sun tanning have most influence on inadequate habits of sun exposure and deficient measures of sun protection. Adolescents should be considered a priority group for targeted interventions to improve sun protection behaviour.


Assuntos
Atitude Frente a Saúde , Neoplasias Cutâneas/prevenção & controle , Estudantes/estatística & dados numéricos , Luz Solar/efeitos adversos , Protetores Solares/administração & dosagem , Adolescente , Fatores Etários , Estudos Transversais , Feminino , Humanos , Masculino , Fatores de Risco , Fatores Sexuais , Fatores Socioeconômicos , Espanha , Queimadura Solar/prevenção & controle , Inquéritos e Questionários
9.
J Phys Ther Sci ; 28(10): 2778-2784, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-27821934

RESUMO

[Purpose] The aims of this study were to verify the effects on upper limb circumferences and total body extracellular water of 10 weeks of Nordic Walking (NW) and Walking (W), both alone and combined with a series of exercises created for breast cancer survivors, the ISA method. [Subjects and Methods] Twenty breast cancer survivors were randomly assigned to 4 different training groups and evaluated for upper limb circumferences, total body and extracellular water. [Results] The breast cancer survivors who performed NW, alone and combined with the ISA method, and Walking combined with the ISA method (but not alone) showed significantly reduced arm and forearm circumferences homolateral to the surgical intervention. [Conclusion] For breast cancer survivors, NW, alone and combined with the ISA method, and Walking combined with the ISA method should be prescribed to prevent the onset and to treat light forms of upper limb lymphedema because Walking training practiced alone had no significant effect on upper limb circumference reduction.

10.
Enferm Infecc Microbiol Clin ; 34(7): 400-5, 2016.
Artigo em Espanhol | MEDLINE | ID: mdl-26976378

RESUMO

INTRODUCTION: The incidence of high-grade anal intraepithelial neoplasia (HGAIN) -with an aetiological based on high-risk types of human papillomavirus- is increasing in some high-risk groups. Screening for HGAIN includes routine anal cytology and, more recently, HPV genotyping. The main objective of this study was to determine the sensitivity and specificity of anal cytology and HPV genotyping for the detection of HGAIN. MATERIALS AND METHODS: This is a study to determine the correlation of cytological and microbiological findings with anal biopsy findings in a cohort of patients at high risk of developing AIN referred to the department of sexually transmitted infections of the Hospital Costa del Sol, Spain, between January 2008 and December 2014. RESULTS: Of the 151 patients subjected to screening, a total of 92 patients, all of them with the result of three screening test (anal cytology, genotyping and biopsy) were included in the study. Just under two-thirds (62%) of them were HIV-positive. The sensitivity and specificity of anal cytology to detect HGAIN were 52.8 and 85.7%, respectively (k: 0.328), and 78 and 62.8% to detect two or more HPV oncogenic genotypes (k: 0.417). The detection of oncogenic HPV genotypes allowed the identification of 23 new cases of HGAIN that had been underdiagnosed with anal cytology, with 14 cases containing at least three high-risk genotypes. CONCLUSION: Anal cytology did not show enough sensitivity in HGAIN screening. HPV genotyping has shown to be a useful tool to detect HGAIN cases, although it could lead to an over-diagnosis as a solitary screening procedure.


Assuntos
Neoplasias do Ânus/diagnóstico , Neoplasias do Ânus/virologia , Carcinoma in Situ/diagnóstico , Carcinoma in Situ/virologia , Papillomaviridae/genética , Infecções por Papillomavirus/diagnóstico , Adulto , Neoplasias do Ânus/patologia , Carcinoma in Situ/patologia , Estudos Transversais , Feminino , Genótipo , Técnicas de Genotipagem , Humanos , Masculino , Sensibilidade e Especificidade , Espanha
11.
J Cancer Educ ; 31(4): 789-795, 2016 12.
Artigo em Inglês | MEDLINE | ID: mdl-26370806

RESUMO

Health professionals are key agents in healthcare promotion. In the field of skin cancer, they play a crucial role in the development of prevention strategies in the community. This paper aims to describe the sun exposure attitudes and habits of public healthcare professionals in the western Costa del Sol (Spain). A cross-sectional descriptive study was conducted in the Costa del Sol healthcare district to analyse sun exposure and protection practices and habits, and attitudes to tanning and sun protection. The respondents, all healthcare personnel in various professional categories and workplace situations, were asked to complete a self-administered questionnaire. Six hundred forty-three workers in the Costa del Sol healthcare district took part in the study. Of these participants, 450 were healthcare professionals. Of the 450 health professionals, 226 (50.2 %) were nurses or auxiliary nursing staff, and the remaining 224 were doctors. These two groups presented differences regarding habits of sun exposure: 15.3 % of the doctors went to the beach at least 30 days a year, compared to 30.9 % of the nurses (p < 0.001). With respect to workplace situation, there were differences (p < 0.001) between the sunburn events reported by healthcare staff who worked in hospitals (52.4 %) compared to those working in primary healthcare (30.4 %); comparable differences were found with respect to attitudes toward the use of sunscreen creams (p = 0.014). This study identifies two distinct subgroups within healthcare personnel: on one hand, primary healthcare professionals, who are key agents for future policy strategies, and on the other, specialist healthcare professionals, who are more likely to suffer sunburn events and therefore toward whom strategies should be addressed to encourage them to change their sun exposure attitudes and habits and sun protection practices.


Assuntos
Hábitos , Comportamentos Relacionados com a Saúde , Conhecimentos, Atitudes e Prática em Saúde , Pessoal de Saúde/psicologia , Neoplasias Cutâneas/psicologia , Queimadura Solar/psicologia , Luz Solar/efeitos adversos , Adulto , Estudos Transversais , Feminino , Humanos , Masculino , Neoplasias Cutâneas/etiologia , Neoplasias Cutâneas/prevenção & controle , Queimadura Solar/etiologia , Queimadura Solar/prevenção & controle , Protetores Solares/uso terapêutico
12.
Breast Care (Basel) ; 11(6): 428-431, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28228712

RESUMO

BACKGROUND: The negative side effects of breast cancer treatments can include upper limb lymphoedema. The growing literature indicates that Nordic walking is an effective discipline against several disease symptoms. The aim of this study was to determine whether introduction to Nordic walking alone is effective against total body extracellular water and upper limb circumferences in breast cancer survivors compared to its combination with a series of specifically created exercises (i.e. the Isa method). METHODS: 16 breast cancer survivors (49.09 ± 2.24 years) were recruited and randomly assigned to 1 of 2 different training groups. RESULTS: 10 lessons on Nordic walking technique plus the Isa method significantly reduced both extracellular body water and the extracellular-to-total body water ratio (p = 0.01 for both), and also the circumference of the upper limb, (both relaxed arm and forearm circumferences) (p = 0.01 for all), whereas Nordic walking alone did not. CONCLUSIONS: Introduction to Nordic walking does not seem to affect lymphoedema in breast cancer survivors. This might be because novice Nordic Walkers do not adequately generate an effective muscular pump through coordination of the alternated bimanual open-close cycle. The Isa method appears to close this gap.

13.
BMC Public Health ; 15: 60, 2015 Jan 31.
Artigo em Inglês | MEDLINE | ID: mdl-25636540

RESUMO

BACKGROUND: Health questionnaires must present accredited measurement properties such as validity, reliability and sensitivity to change, the latter being essential for interventions to be planned and for evaluating their effectiveness. The aim of this study was to evaluate the sensitivity to change of a Beach Questionnaire. METHODS: Quasi-experimental before-after study carried out in 2011, for a study population of adolescents attending schools in the Costa del Sol. First, the questionnaire was administered to the adolescents, after which a multicomponent educational intervention was carried out; finally, three months later, the same questionnaire was re-administered to the same adolescents. Changes were assessed in the categories of each item, using the McNemar test, and the changes in the scores, standardised to a range of 0-100, using the Student t test for paired samples, and including the mean of the differences and the 95% confidence interval. The level of statistical significance was set at p < 0.05. RESULTS: 228 adolescents, aged 14-17 years, and 55.3% were girls. Statistically significant changes were observed in sunburn experiences, exposure to the sun at mid-day and attitudes to sun exposure and suncreams. For the seven items related to knowledge about sun exposure, a higher rate of correct answers was observed. The analysis of changes, within the standardised range, revealed a significant improvement in the scores for sun exposure habits (MD 4.33; CI 95% 2.2-6.5), attitudes to sun exposure (MD 2.22; CI 95% 1.2-3.2) and knowledge (MD 9.10; CI 95% 7.1-11.1), but not in those for sun-protection practices (MD 0.23; CI 95% -1.2-1.7). CONCLUSIONS: The Beach Questionnaire on behaviour, attitudes and knowledge related to sun exposure is the first such instrument in Spanish language to provide sufficient sensitivity to change. It constitutes a useful tool for epidemiologic research into photoprotection and for skin cancer prevention programmes.


Assuntos
Comportamento do Adolescente , Conhecimentos, Atitudes e Prática em Saúde , Queimadura Solar/diagnóstico , Queimadura Solar/epidemiologia , Inquéritos e Questionários/normas , Adolescente , Estudos Controlados Antes e Depois , Feminino , Humanos , Masculino , Psicometria , Reprodutibilidade dos Testes , Espanha , Queimadura Solar/prevenção & controle , Luz Solar/efeitos adversos
14.
Dermatol Ther ; 27(6): 337-42, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25081902

RESUMO

Periungual warts represent a treatment challenge because of its high recurrence rate and recalcitrance. These are benign lesions produced by the human papilloma virus (HPV) that often do not respond to habitual treatment. Cidofovir is a potent antiviral drug that acts inactivating viral DNA polymerase. Topical cidofovir for the treatment of HPV-related cutaneous and mucous lesions is becoming increasingly common. Our aim was to assess the efficacy and safety of cidofovir cream for the treatment of viral periungual warts. We undertook a retrospective observational study of patients with periungual warts who received treatment with topical cidofovir between January 2010 and December 2013 at the Dermatology Service of the Hospital Costa del Sol, Marbella, Spain. Data were recorded about the rate of treatment response, the adverse effects and recurrences, as well as the characteristics of the patient cohort. We identified 41 patients who had received some previous treatment. The concentration of cidofovir was 3% in all cases, usually applied twice a day (in 37 of the 41 cases). A greater or lesser response was noted in 35 cases. There were six recurrences in the follow-up period. Topical cidofovir seems to be a useful alternative for the therapeutic management of recalcitrant periungual common warts that fail to respond to usual treatment. Our experience with the use of this antiviral agent has been satisfactory, although in our opinion, it should be reserved for specific cases as its economical cost represents an important limitation.


Assuntos
Antivirais/administração & dosagem , Citosina/análogos & derivados , Doenças da Unha/tratamento farmacológico , Organofosfonatos/administração & dosagem , Infecções por Papillomavirus/tratamento farmacológico , Verrugas/tratamento farmacológico , Administração Tópica , Adolescente , Adulto , Antivirais/efeitos adversos , Criança , Pré-Escolar , Cidofovir , Citosina/administração & dosagem , Citosina/efeitos adversos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doenças da Unha/diagnóstico , Doenças da Unha/virologia , Organofosfonatos/efeitos adversos , Infecções por Papillomavirus/diagnóstico , Infecções por Papillomavirus/virologia , Recidiva , Indução de Remissão , Estudos Retrospectivos , Espanha , Fatores de Tempo , Resultado do Tratamento , Verrugas/diagnóstico , Verrugas/virologia , Adulto Jovem
15.
Enferm Infecc Microbiol Clin ; 32(9): 560-4, 2014 Nov.
Artigo em Espanhol | MEDLINE | ID: mdl-24908497

RESUMO

INTRODUCTION: The incidence of intraepithelial anal neoplasia is increasing in certain risk behaviour groups, and human papillomavirus (HPV) infection is involved in its pathogenesis. The systematic use of anal cytology, and more recently HPV detection by hybrid capture and genotyping, have been introduced into screening programs in recent decades. MATERIAL AND METHODS: A retrospective cohort study was carried out on individuals with risk behaviours of developing intraepithelial anal neoplasia and who attended Sexually Transmitted Infections clinics in the Dermatology area of the Hospital Costa del Sol from January 2010 to December 2012. The intraepithelial anal neoplasia screening was performed using anal cytology and HPV genotyping. RESULTS: Half (50%) of the study population were HIV positive. A high frequency of anal dysplasia and presence of HPV in cytology (82.1%) and genotype (79%) was found. A statistically significant association (P<.005) was obtained between the presence of high-risk HPV genotypes and the presence of high-grade dysplasia in the second directed cytology. HPV genotyping enabled 17 cases (22%) of severe dysplasia to be identified that were under-diagnosed in the first cytology. CONCLUSION: Cases of high-grade dysplasia can be under-diagnosed by a first anal cytology. Detection of HPV can supplement this procedure, leading to the identification of those patients most at risk of developing high-grade anal dysplasia.


Assuntos
Neoplasias do Ânus/virologia , Carcinoma in Situ/virologia , Detecção Precoce de Câncer/métodos , Infecções por Papillomavirus/diagnóstico , Infecções Tumorais por Vírus/diagnóstico , Adulto , Neoplasias do Ânus/epidemiologia , Neoplasias do Ânus/patologia , Neoplasias do Ânus/prevenção & controle , Carcinoma in Situ/epidemiologia , Carcinoma in Situ/patologia , Carcinoma de Células Escamosas/prevenção & controle , Feminino , Genótipo , Humanos , Masculino , Papillomaviridae/genética , Papillomaviridae/isolamento & purificação , Papillomaviridae/patogenicidade , Infecções por Papillomavirus/epidemiologia , Estudos Retrospectivos , Risco , Assunção de Riscos , Comportamento Sexual , Infecções Sexualmente Transmissíveis/epidemiologia , Método Simples-Cego , Espanha/epidemiologia , Infecções Tumorais por Vírus/epidemiologia
16.
Eur J Dermatol ; 24(1): 85-93, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24566265

RESUMO

BACKGROUND: A history of sunburn and cumulative sun exposure during adolescence are the most important risk factors for the development of skin cancer. Skin cancer can be prevented by reducing sun exposure, particularly during adolescence, which is precisely the age group that could best benefit from primary prevention campaigns. OBJECTIVE: To determine the behaviour, attitudes and understanding of adolescents concerning sun exposure. METHODS: This cross-sectional descriptive study undertaken during 2011 included secondary school adolescents from randomly selected schools on the Costa del Sol, southern Spain. A validated beachside questionnaire was used to record data on demographics, skin colour, phototype, sun exposure habits, sunburns, practices, attitudes and knowledge about the sun. RESULTS: The study involved 270 students, aged 14-17 years, from 11 schools; 50.4% were female, 43.7% were aged 14 years, and 85.9% were Spanish. Most had a light skin colour (49.3%) and phototypes III (42.2%) or IV (34.8%). Most (71%) went to the beach on more than 16 days and 74.4% had had sunburn the previous summer. Sun cream was used by 47.8% and 1.1% wore long sleeves or trousers. Concerning attitudes, 60.7% stated they felt better when they were tanned, and concerning understanding, most were aware of the harmful effects of the sun on the skin. CONCLUSION: Adolescents comprise a special risk group with a positive attitude towards tanning. Further studies are required to assess educational stategies in order to reduce the desire to have a suntan, and improve sun protection practices and habits targeted at this age group.


Assuntos
Comportamento do Adolescente , Conhecimentos, Atitudes e Prática em Saúde , Banho de Sol , Luz Solar/efeitos adversos , Adolescente , Estudos Transversais , Feminino , Humanos , Masculino , Espanha
17.
Dermatol Ther ; 27(2): 89-93, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24433270

RESUMO

Plantar warts are a common reason for dermatological consultations and their treatment can occasionally be a challenge. Plantar warts are benign lesions produced by the human papillomavirus (HPV) that often fail to respond to habitual treatment. Cidofovir is a potent antiviral drug that acts competitively, inhibiting viral DNA polymerase. Our aim was to assess the efficacy and safety of cidofovir cream for the treatment of viral plantar warts. We undertook a retrospective observational study of patients with plantar warts who received treatment with topical cidofovir between July 2008 and July 2011 at the Dermatology Service of the Hospital Costa del Sol, Marbella, Spain. Data about the rate of treatment response, the adverse effects, and recurrences, as well as the characteristics of the patient cohort, were recorded. We identified 35 patients who had received some previous treatment. The usual concentration was 3% (in 33 of 35 cases), applied twice a day (in 31 of 35 cases). A greater or lesser response was noted in 28 cases. There were two recurrences. Topical cidofovir seems to be a useful alternative for the therapeutic management of recalcitrant plantar common warts that fail to respond to usual treatment.


Assuntos
Antivirais/administração & dosagem , Citosina/análogos & derivados , Dermatoses do Pé/tratamento farmacológico , Organofosfonatos/administração & dosagem , Verrugas/tratamento farmacológico , Administração Cutânea , Adolescente , Adulto , Antivirais/efeitos adversos , Criança , Cidofovir , Citosina/administração & dosagem , Citosina/efeitos adversos , Esquema de Medicação , Feminino , Dermatoses do Pé/diagnóstico , Dermatoses do Pé/virologia , Humanos , Masculino , Pessoa de Meia-Idade , Organofosfonatos/efeitos adversos , Recidiva , Estudos Retrospectivos , Espanha , Fatores de Tempo , Resultado do Tratamento , Verrugas/diagnóstico , Verrugas/virologia , Adulto Jovem
18.
Enferm Infecc Microbiol Clin ; 31(4): 222-6, 2013 Apr.
Artigo em Espanhol | MEDLINE | ID: mdl-23182242

RESUMO

BACKGROUND: Cidofovir is an antiviral agent which inhibits the DNA polymerase of different viruses. Its use has been described for papillomavirus infections. METHODS: Descriptive retrospective study, including patients with difficult to treat anogenital warts who were treated with cidofovir cream. RESULTS: Nine immunocompetent patients were treated, where 6 of them had a complete response and 3 of them a partial response. CONCLUSION: Cidofovir cream could be a useful therapeutic alternative, although further studies are required to establish the best dosage and its cost-effectiveness.


Assuntos
Antivirais/uso terapêutico , Doenças do Ânus/tratamento farmacológico , Condiloma Acuminado/tratamento farmacológico , Citosina/análogos & derivados , Doenças dos Genitais Masculinos/tratamento farmacológico , Organofosfonatos/uso terapêutico , Administração Tópica , Adulto , Aminoquinolinas/uso terapêutico , Antivirais/administração & dosagem , Doenças do Ânus/cirurgia , Criança , Cidofovir , Terapia Combinada , Condiloma Acuminado/cirurgia , Crioterapia , Citosina/administração & dosagem , Citosina/uso terapêutico , Suscetibilidade a Doenças , Avaliação de Medicamentos , Farmacorresistência Viral , Eletrocoagulação , Feminino , Doenças dos Genitais Femininos/tratamento farmacológico , Doenças dos Genitais Femininos/cirurgia , Doenças dos Genitais Masculinos/cirurgia , Humanos , Imiquimode , Imunocompetência , Masculino , Organofosfonatos/administração & dosagem , Podofilotoxina/uso terapêutico , Indução de Remissão , Estudos Retrospectivos , Adulto Jovem
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