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1.
Artigo em Inglês | MEDLINE | ID: mdl-33256186

RESUMO

Due to the increase of sports events in local communities, it has become essential to organize such events in a socially responsible way at the environmental, social, and economic levels. The aim of this research was to develop a measurement tool to help determine the degree of social responsibility perceived by residents at small-medium scale sports events, to guide sports managers towards the design of socially responsible sports events. From the elaboration of a questionnaire developed ad-hoc, the perception of the residents was analyzed (n = 516). The psychometric properties of the tool, composed of 35 items, were analyzed by means of an exploratory and confirmatory factor analysis. As main conclusions, we were able to contrast the validity and reliability of the questionnaire on the perception of corporate social responsibility in small-scale sports events, around the dimensions of Sustainable Sports Activity, Social Cohesion, and Well-Being. As a consequence, it allowed us to identify three strategic management areas towards which the organizers of these events should focus special attention if they want to progress towards the achievement of socially responsible sports events.


Assuntos
Responsabilidade Social , Esportes , Humanos , Opinião Pública , Reprodutibilidade dos Testes , Inquéritos e Questionários
3.
Front Psychol ; 11: 547846, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33101123

RESUMO

One of the main objectives of fitness center managers is to obtain high levels of loyalty from the customers of these fitness centers. Within the existing literature on fitness center management, previous research has analyzed the importance of the management variables themselves to determine the behavioral intentions of their customers, ignoring other psychological and sociodemographic aspects and focusing on linear relationship models. Therefore, this study, which aims to analyze the impact of different management variables along with psychological (emotions and subjective well-being) and demographic variables (age and sex) on the satisfaction, perceived value (PV) and future intentions (FI) of 398 users (216 men, aged 18-75, Mean = 35.89 ± 14.53) of a fitness center, intends to fill this gap. In this study, two different methodologies are used, i.e., hierarchical regressions models (HRM) and qualitative comparative analysis (QCA). The data were obtained by means of a self-administered questionnaire composed of 69 items that collected different previously validated scales. Considering HRM, the different models proposed explain 52% of the satisfaction variance, 57% of perceived value and 59% of future intentions. In general, it seems that the management variables are better predictors than subjective well-being, emotions and age or gender since their inclusion does not greatly improve the model's predictive capacity. As far as QCA analyses are concerned, it seems that none of the conditions are necessary for high or low levels of satisfaction, perceived value or future intentions. On the other hand, based on sufficiency analyses, there seem to be 8 pathways or combinations of conditions leading to high levels of satisfaction and 13 for low levels, 11 combinations leading to high levels of IF and 10 leading to low levels; however, there are 6 combinations of conditions leading to high levels of PV and 5 leading to low levels. In general, some of the pathways consider only the management variables, although many of them consider the importance not only of the management variables but also of the interactions that these may have with emotional aspects and, to a lesser extent, with age and well-being. When comparing both methodologies, it can be observed that the QCA models are more explanatory than the HRM models and that they take into account aspects that seem unimportant when observing linear models (such as emotions or age). However, both methodologies should be considered complementary and used simultaneously since, by focusing on different aspects, enriched results are obtained. The results obtained will enable managers to make more efficient use of available resources to increase user satisfaction.

4.
Artigo em Inglês | MEDLINE | ID: mdl-32560191

RESUMO

The acquisition of physical activity habits during adolescence is fundamental to guarantee its adherence throughout life. However, these levels decrease during this stage, with women experimenting a more significant decrease. This paper aims to analyze if there are significant differences in the variables related to the intention to be physically active between men and women and if there is a moderating effect of gender on the variables that predict this intention. The sample is composed of 256 adolescents, aged between 16 and 19 years, 55.50% of whom are men, and 44.50% women. The results show that there are statistically significant differences (p < 0.05), with boys showing higher scores in the intention, athletic identity, and in the strength, condition, and attractiveness. About the predictive variables of the intention, the gender moderates the relationships between the physical attractiveness, condition and strength with the perceived behavioral control (pcfmale-pcfmale = 0.44; -0.48 p < 0.001; 0.27, p < 0.05, respectively), and between the subjective norm and the intention to be physically active (pcmale-female = 0.33, p < 0.01). These results highlight the importance of considering gender when designing specific policies for the promotion of physical-sports practice among adolescents to reduce the existing gender gap.


Assuntos
Intenção , Esportes , Adolescente , Exercício Físico , Feminino , Humanos , Masculino , Reprodutibilidade dos Testes , Fatores Sexuais , Adulto Jovem
5.
Artigo em Inglês | MEDLINE | ID: mdl-31817962

RESUMO

This study analyses the sporting habits of runners participating in short-distance urban running events to identify groups with different motivations towards the practice of endurance running and participation in urban running events. A sample consisting of 937 participants in the Valencia running circuit was interviewed using a questionnaire consisting of a scale of 22 items to analyse their motives for participating in popular races. An exploratory and confirmatory factorial analysis was carried out to check the validity of the instrument, and the analysis identified the following four factors into which the indicators were grouped: psychological and physical motives (3 items), social motives and interest in running events (5 items), occupation of time and social recognition (6 items) and competitive and material motives (3 items). Subsequently, a cluster analysis was performed by combining hierarchical and non-hierarchical methods, and the analysis identified the following three groups of runners with different characteristics: individual hedonists (n = 276), enthusiasts (n = 312) and socializing hedonists (n = 349). Enthusiastic runners consider most motives important when participating in running events, individual hedonists consider individual psychological and physical motives important, and socializing hedonists consider personal and social motives and interest in sport important. Variables related to age, educational level, annual income level, frequency of running, how the individuals went out to run and the level of the runners contributed to differentiating the identified groups. The results confirm the heterogeneous nature of urban runners.


Assuntos
Hábitos , Motivação , Corrida , Esportes/psicologia , População Urbana , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Inquéritos e Questionários
6.
Front Psychol ; 10: 2089, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31572270

RESUMO

The aim of this paper was to study the combined effects of tactical and contextual dimensions on achieving offensive performance in open play possessions from Spanish "La Liga" soccer matches. 1860 team possessions from 20 random matches were evaluated by means of multidimensional observation. Multilevel regression models were constructed to predict the probability to achieve offensive performance according to the tactical and contextual dimensions registered in each possession. Performing penetrative actions after recovering the ball (OR = 1.497; 95% CI: 1.022-2.192; P < 0.05), and progressing by fast attacks (OR = 3.588; 95% CI: 2.045-6.294; p < 0.001) or counterattacks (OR = 7.097; 95% CI: 3.530-14.269; P < 0.001) was more effective to create scoring opportunities than performing a non-penetrative action and progressing by combinative attack, respectively. Also, progressing by long possessions (OR = 5.057; 95% CI: 2.406-10.627; p < 0.001) was more effective than progressing by short possessions to create scoring opportunities. As for contextual dimensions, multivariate analyses showed how playing at home and against high-ranked opponents registered more likelihood of achieving offensive penetration, although no associations were found in the production of scoring opportunities. Tactical dimensions as initial penetration, type of attack and possession length played an important role on achieving offensive penetration and goal scoring opportunities in Spanish Soccer "La Liga".

7.
Physiol Behav ; 200: 159-165, 2019 03 01.
Artigo em Inglês | MEDLINE | ID: mdl-29859238

RESUMO

Sporting events can be announced using sports posters and by disseminating advertisements on the internet, on the street and in print media. But until now, no prior research has measured the effectiveness of sponsorship in sporting event posters. This study uses eye tracking to measure the effectiveness of sporting event posters and proposes considering the level of the viewer's attention as an indicator. This research involves a factorial experiment based on the following variables: congruence, the number of sponsors, and placement of the sponsor's advertisement in a sporting event poster. The results indicate that sponsors positioned in the poster's area of action receive more attention. However, we were unable to prove that congruent sponsors receive more attention, as claimed in the literature. This result could be due to a situation of blindness towards the sponsor. The conclusion section of this paper discusses theoretical conclusions and potential managerial actions.


Assuntos
Publicidade , Atenção , Movimentos Oculares , Esportes , Medições dos Movimentos Oculares , Feminino , Humanos , Masculino , Esportes/psicologia , Percepção Visual , Adulto Jovem
8.
Eur J Cancer Care (Engl) ; 27(4): e12861, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29869823

RESUMO

Adiposity and physical activity are modifiable factors that could be important determinants of breast cancer (BC) prognosis through their effects on endogenous reproductive hormones, chronic inflammation and metabolic changes. Therefore, it is necessary to evaluate whether offering lifestyle interventions to BC survivors could affect the levels of certain biomarkers involved in these mechanisms. We designed a pre-post intervention study offering diet and exercise sessions over 12 weeks to 42 overweight/obese BC survivors. Before and after the intervention, we obtained dietary information, anthropometry and cardiorespiratory fitness (CRF) measurements and blood samples to measure metabolic risk, insulin resistance and adipokines biomarkers. Wilcoxon signed-rank tests and Spearman partial correlation coefficients were used to compare pre- and post-measurements and assess the correlations between changes in biomarkers and changes in anthropometry and CRF. Breast cancer survivors showed significant improvements in metabolic risk biomarkers and insulin resistance indicators along with a non-significant leptin decrease and a significant adiponectin decrease. The improvements in metabolic risk biomarkers, insulin resistance indicators and leptin were moderately correlated (0.32 ≤ |r| ≤ 0.55) with the decrease in body mass index and the increase in CRF. Diet and exercise interventions implemented in overweight/obese BC survivors may improve metabolic risk, insulin resistance and leptin biomarkers.


Assuntos
Adiponectina/metabolismo , Neoplasias da Mama , Sobreviventes de Câncer , Dietoterapia/métodos , Exercício Físico , Resistência à Insulina , Leptina/metabolismo , Obesidade/terapia , Sobrepeso/terapia , Comportamento de Redução do Risco , Glicemia/metabolismo , Índice de Massa Corporal , Aptidão Cardiorrespiratória , Feminino , Humanos , Pessoa de Meia-Idade , Obesidade/metabolismo , Sobrepeso/metabolismo
9.
Front Psychol ; 9: 2646, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30662420

RESUMO

Multisource assessment (MSA) is based on the belief that assessments are valid inferences about an individual's behavior. When used for performance management purposes, convergence of views among raters is important, and therefore testing factor invariance across raters is critical. However, when MSA is used for development purposes, raters usually come from a greater number of contexts, a fact that requires a different data analysis approach. We revisit the MSA data analysis methodology when MSA is used for development, with the aim of improving its effectiveness. First, we argue that having raters from different contexts is an integral element of the assessment, with the trait-context dyad being the actual latent variable. This leads to the specification of an Aggregate (instead of the usual Latent) multidimensional factor model. Second, since data analysis usually aggregates scores for each rater group into a single mean that is then compared with the self-rating score, we propose that the test for factor invariance must also include scalar invariance, a pre-requisite for mean comparison. To illustrate this methodology we conducted a 360° survey on a sample of over 1100 MBA students enrolled in a leadership development course. Finally, by means of the study we show how the survey can be customized to each rater group to make the MSA process more effective.

10.
Front Oncol ; 7: 283, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29250484

RESUMO

FN14 has been implicated in many intracellular signaling pathways, and GRP94 is a well-known endoplasmic reticulum protein regulated by glucose. Recently, both have been associated with metastasis progression in breast cancer patients. We studied the usefulness of FN14 and GRP94 expression to stratify breast cancer patients according their risk of brain metastasis (BrM) progression. We analyzed FN14 and GRP94 by immunohistochemistry in a retrospective multicenter study using tissue microarrays from 208 patients with breast carcinomas, of whom 52 had developed BrM. Clinical and pathological characteristics and biomarkers expression in Luminal and non-Luminal patients were analyzed using a multivariate logistic regression model adjusted for covariates, and brain metastasis-free survival (BrMFS) was estimated using the Kaplan-Meier method and the Cox proportional hazards model. FN14 expression was associated with BrM progression mainly in Luminal breast cancer patients with a sensitivity (53.85%) and specificity (89.60%) similar to Her2 expression (46.15 and 89.84%, respectively). Moreover, the likelihood to develop BrM in FN14-positive Luminal carcinomas increased 36.70-fold (3.65-368.25, p = 0.002). Furthermore, the worst prognostic factor for BrMFS in patients with Luminal carcinomas was FN14 overexpression (HR = 8.25; 95% CI: 2.77-24.61; p = 0.00015). In these patients, GRP94 overexpression also increased the risk of BrM (HR = 3.58; 95% CI: 0.98-13.11; p = 0.054-Wald test). Therefore, FN14 expression in Luminal breast carcinomas is a predictive/prognostic biomarker of BrM, which combined with GRP94 predicts BrM progression in non-Luminal tumors 4.04-fold (1.19-8.22, p = 0.025), suggesting that both biomarkers are useful to stratify BrM risk at early diagnosis. We propose a new follow-up protocol for the early prevention of clinical BrM of breast cancer patients with BrM risk.

11.
Oncotarget ; 6(42): 44254-73, 2015 Dec 29.
Artigo em Inglês | MEDLINE | ID: mdl-26497551

RESUMO

Brain metastasis is a devastating problem in patients with breast, lung and melanoma tumors. GRP94 and FN14 are predictive biomarkers over-expressed in primary breast carcinomas that metastasized in brain. To further validate these brain metastasis biomarkers, we performed a multicenter study including 318 patients with breast carcinomas. Among these patients, there were 138 patients with metastasis, of whom 84 had brain metastasis. The likelihood of developing brain metastasis increased by 5.24-fold (95%CI 2.83-9.71) and 2.55- (95%CI 1.52-4.3) in the presence of FN14 and GRP94, respectively. Moreover, FN14 was more sensitive than ErbB2 (38.27 vs. 24.68) with similar specificity (89.43 vs. 89.55) to predict brain metastasis and had identical prognostic value than triple negative patients (p < 0.0001). Furthermore, we used GRP94 and FN14 pathways and GUILD, a network-based disease-gene prioritization program, to pinpoint the genes likely to be therapeutic targets, which resulted in FN14 as the main modulator and thalidomide as the best scored drug. The treatment of mice with brain metastasis improves survival decreasing reactive astrocytes and angiogenesis, and down-regulate FN14 and its ligand TWEAK. In conclusion our results indicate that FN14 and GRP94 are prediction/prognosis markers which open up new possibilities for preventing/treating brain metastasis.


Assuntos
Biomarcadores Tumorais/metabolismo , Neoplasias Encefálicas/metabolismo , Neoplasias Encefálicas/secundário , Neoplasias da Mama/metabolismo , Neoplasias da Mama/patologia , Carcinoma Ductal de Mama/metabolismo , Carcinoma Ductal de Mama/secundário , Glicoproteínas de Membrana/metabolismo , Receptores do Fator de Necrose Tumoral/metabolismo , Adulto , Idoso , Idoso de 80 Anos ou mais , Inibidores da Angiogênese/uso terapêutico , Animais , Área Sob a Curva , Astrócitos/efeitos dos fármacos , Astrócitos/metabolismo , Astrócitos/patologia , Biomarcadores Tumorais/genética , Neoplasias Encefálicas/tratamento farmacológico , Neoplasias Encefálicas/genética , Neoplasias da Mama/tratamento farmacológico , Neoplasias da Mama/genética , Carcinoma Ductal de Mama/tratamento farmacológico , Carcinoma Ductal de Mama/genética , Linhagem Celular Tumoral , Citocina TWEAK , Feminino , Humanos , Imuno-Histoquímica , Funções Verossimilhança , Glicoproteínas de Membrana/genética , Camundongos Nus , Pessoa de Meia-Idade , Medicina de Precisão , Valor Preditivo dos Testes , Prognóstico , Curva ROC , Receptores do Fator de Necrose Tumoral/genética , Medição de Risco , Fatores de Risco , Espanha , Receptor de TWEAK , Talidomida/uso terapêutico , Análise Serial de Tecidos , Microambiente Tumoral , Fatores de Necrose Tumoral/metabolismo , Ensaios Antitumorais Modelo de Xenoenxerto , Adulto Jovem
12.
J Contemp Brachytherapy ; 6(4): 397-403, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25834585

RESUMO

PURPOSE: To demonstrate the utility of a boost with interstitial brachytherapy (BT) in breast-conserving therapy (BCT) by doing a thorough review of the literature and describing in detail our technique for delivering this boost. MATERIAL AND METHODS: Our department has been delivering the boost with interstitial BT since 1989, in most cases with rigid needles and a theoretical dosimetry. In the early years, we used low-dose-rate (LDR) with iridium-192 wires. The dose administered was 15 Gy if there were no risk factors for local relapse or 20-25 Gy in the presence of risk factors. The risk factors considered were the presence of a close margin (less than 10 mm) and an extensive intraductal component (more than 25%). After 2002, we switched to high-dose-rate (HDR); using the linear quadratic model we changed the low dose to 3 fractions of 4.5 Gy in the case of no risk factors for local relapse or to 3 fractions of 5 Gy in the presence of risk factors. RESULTS: In 79 consecutive boost patients treated in our department between 2010 and 2011, with a median follow-up of 46 months, the local control rate was 97.47%. With respect to cosmesis, fibrosis occurred in 17 cases (21.5%) and hyperpigmentation in 26 cases (32.9%). Our hospital's results are comparable in terms of local control and cosmesis to those of other authors. CONCLUSIONS: This educational article describes our department's boost technique with rigid needles and comments briefly on our results using this technique in a group of consecutively treated patients in our department. A review of the literature and the published results on local control and cosmesis is also described.

13.
Women Health ; 55(5): 505-24, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25833659

RESUMO

This study assessed changes in quality of life (QoL) and cardiorespiratory fitness (CRF) during a diet and physical activity (PA) intervention in breast cancer (BC) survivors and investigated the relation between these changes. The intervention of this single-arm pre-post study involved supervised, 1-hour weekly, diet sessions and 75-minute bi-weekly PA sessions of moderate-to-high intensity. This 12-week intervention targeted overweight/obese women who had recently completed BC treatment. Pre- and post-CRF and QoL measurements were compared using paired t-tests. Linear regression models, including baseline participants' characteristics and weight change, were used to assess the association between changes in CRF and QoL. The 37 BC survivors who completed the intervention between May 7, 2012 and July 27, 2012 showed significant increases in CRF and QoL. Peak oxygen uptake (mL/kg/min) increased from 19.0 ± 2.8 to 24.0 ± 4.1 while peak workload (watts/kg) increased from 1.3 ± 0.3 to 1.7 ± 0.3. Although statistical significance was not reached, the increase in workload seemed associated with increases in physical, mental, and general health and with a decrease in fatigue. This lifestyle intervention improved BC survivors' QoL and CRF and suggested possible relationships between CRF and QoL. More research needs to confirm these associations and promote lifestyle interventions aiming at improving BC survivors' QoL.


Assuntos
Neoplasias da Mama/reabilitação , Teste de Esforço , Terapia por Exercício/métodos , Obesidade/complicações , Aptidão Física/fisiologia , Qualidade de Vida , Sobreviventes/psicologia , Adulto , Idoso , Índice de Massa Corporal , Neoplasias da Mama/fisiopatologia , Neoplasias da Mama/psicologia , Dieta , Fadiga , Feminino , Nível de Saúde , Humanos , Estilo de Vida , Modelos Lineares , Pessoa de Meia-Idade , Obesidade/terapia , Cooperação do Paciente/estatística & dados numéricos , Inquéritos e Questionários
14.
Motriz rev. educ. fís. (Impr.) ; 20(2): 151-157, Apr-Jun/2014. tab, graf
Artigo em Inglês | LILACS | ID: lil-715631

RESUMO

The purpose of this study was to analyze the psychometric properties of a brief version of the AF5 questionnaire (García & Musitu, 2001) using exploratory and confirmatory techniques on a preadolescent population in the Valencian community (Spain). The sample was made up of 541 participants between 10 and 12 years old, 55.1% (298) boys and 44.9% (243) girls. After observing the results of different reliability and validity analyses (exploratory factor analysis (EFA) and confirmatory factor analysis (CFA)), it was found that the reduced scale consisting of 20 items showed a similar reliability and validity to the original scale. The factorial structure also fits that of the original model established a priori. According to the results of the study, the use of this diagnostic tool with Spanish children seems justified...


O objetivo deste estudo foi analisar as propriedades psicométricas de uma versão reduzida do questionário AF5 (Garcia & Musitu, 2001), utilizando técnicas exploratórias e confirmatórias, em uma população pré-adolescente na comunidade Valenciana (Espanha). A amostra foi composta de 541 participantes entre 10 e 12 anos de idade, 55,1% do sexo masculino (298) e 44,9% do sexo feminino (243). Depois de observar os resultados de diferentes análises de confiabilidade e validade (análise fatorial exploratória (EFA) e análise fatorial confirmatória (CFA)), verificou-se que o questionário reduzido, composto por 20 itens, mostrou uma confiabilidade e validade semelhantes aos do questionário original. A estrutura fatorial também se encaixa no modelo original estabelecido a priori. De acordo com os resultados da pesquisa, o uso desta ferramenta de diagnóstico com crianças espanholas parecem justificados...


El objetivo de este estudio fue analizar las propiedades psicométricas de una versión abreviada del cuestionario AF5 (García & Musitu, 2001) utilizando técnicas exploratorias y confirmatorias en una población preadolescente en la comunidad Valenciana (España). La muestra se compone de 541 participantes entre 10 y 12 años de edad, 55.1% niños (298) y el 44,9% niñas (243). Tras observar los resultados de diferentes análisis de fiabilidad y validez (análisis factorial exploratorio (EPT) y el análisis factorial confirmatorio (CFA)), se encontró que la escala reducida consistente en 20 ítems mostró una fiabilidad y validez similar a la escala original. La estructura factorial también se ajusta a la del modelo original establecida a priori. De acuerdo con los resultados del estudio, el uso de esta herramienta de diagnóstico con niños españoles parece justificado...


Assuntos
Humanos , Masculino , Feminino , Criança , Atividade Motora
15.
Movimento (Porto Alegre) ; 20(1): 261-280, jan.- mar. 2014.
Artigo em Inglês, Espanhol | LILACS | ID: biblio-995140

RESUMO

El objetivo de este estudio es analizar la percepción de los residentes sobre el impacto cultural y deportivo del Gran Premio de Europa de Fórmula 1. Se realizó un análisis clúster, combinando métodos jerárquicos y no jerárquicos, que permitió encontrar tres grupos con percepciones diferentes hacia este evento deportivo: Desfavorables, Desfavorables Moderados y Favorables Moderados. Los residentes consideran de forma mayoritaria que este evento no tiene un impacto considerable a nivel cultural y deportivo. Asimismo, se encontraron diferencias entre los tres grupos de residentes en función del interés por la Fórmula 1, el respaldo al evento, la asistencia y el grado de identificación


O objetivo do estudo é analisar a percepção dos residentes em relação ao impacto cultural e desportivo do Grande Prêmio da Europa de Fórmula 1. Realizou-se uma análise cluster, combinando métodos hierárquicos e não hierárquicos, que permitiu encontrar três grupos com percepções diferentes frente a este evento esportivo: Desfavoráveis, Desfavoráveis Moderados e Favoráveis Moderados. Os residentes consideram em sua maioria que este evento não tem um impacto considerável no nível cultural e esportivo. Também se encontraram diferenças entre os três grupos de residentes em função do interesse pela Fórmula 1, o respaldo ao evento, a assistência e o grau de identificação


The aim of this study is to analyze the resident's perception about the cultural and sport impact of European Formula 1 Grand Prix. Cluster analysis was performed by combining hierarchical and nonhierarchical methods, which allowed us to differentiate three groups with different perceptions towards sporting event: Unfavorable, Moderate Unfavorable and Moderate Favorable. Most residents believe that this event has no significant impact to cultural and sporting level. Also, differences were found between the three groups of residents in the interest of Formula 1, the support for the event, attendance and the degree of identification


Assuntos
Humanos , População , Percepção Social , Esportes , Fatores Culturais
16.
Breast ; 23(4): 299-309, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24530095

RESUMO

The demand for breast cancer care has increased as cancer treatment innovations have proliferated. Adjuvant radiotherapy to the breast is considered to be part of the standard treatment in breast cancer. The role of radiotherapy in terms of reducing loco-regional recurrence and increased survival after conservative surgery, and also after a mastectomy in selected cases, has been previously shown in several randomized trials. Patterns of radiotherapy commonly used for breast cancer comprise a period of approximately five weeks, frequently with the addition of an additional 1-1.5 weeks of a radiation boost to the primary tumour area. In last years, there has been a renewed interest in hypofractionated and accelerated radiotherapy schedules that reduce the overall treatment time to barely three weeks, leading to an improvement in quality of life for patients and also optimizing workload of radiation oncology departments. However, despite the existing evidence supporting the use of hypofractionated treatment regimens, their widespread is still far from complete. Many questions have generated resistance among clinical oncologists for their regular use. The aim of this review is to answer those questions that may arise with the use of moderate hypofractionation in breast cancer.


Assuntos
Neoplasias da Mama/radioterapia , Carcinoma Ductal de Mama/radioterapia , Carcinoma Intraductal não Infiltrante/radioterapia , Fracionamento da Dose de Radiação , Feminino , Humanos , Mastectomia , Radioterapia Adjuvante/métodos
17.
Brachytherapy ; 13(4): 380-7, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-23896397

RESUMO

PURPOSE: Penis brachytherapy (PB) remains an alternative in the cancer treatment. The objective of this study was to assess the oncologic outcomes, sexual function, and the sexual behavior of men treated by PB for a cancer of the penis. METHODS AND MATERIALS: Between 1992 and 2009, 47 patients with a cancer of the penis were treated by PB ((192)Ir), in the Toulouse, Montpellier, and Barcelona cancer centers. The investigation into their sexuality was obtained by means of questionnaire. A total of 21 French patients were approached, of whom 19 (mean age=73.2 years) agreed to answer the questionnaire (participation rate=90.5%). RESULTS: Oncologic data: The specific survival and the disease-free survival at 5 years was 87.6% (95% confidence interval, 72.4-94.7%) and 84% (95% confidence interval, 57.6-94.7%), respectively. The rate of preservation of the penis was 66% (n=31). Sexual data: Among the 17 patients sexually active before brachytherapy, 10 patients remained sexually active after treatment (58.8%). Of the 18 patients who had erections before PB, 17 still had them after treatment (94.4%). Age was the main predictive factor. CONCLUSION: The PB seems to have a moderated impact on the sexual functions and the sexual behavior of the patients.


Assuntos
Braquiterapia/efeitos adversos , Carcinoma/diagnóstico por imagem , Neoplasias Penianas/radioterapia , Disfunções Sexuais Fisiológicas/etiologia , Disfunções Sexuais Psicogênicas/etiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Braquiterapia/métodos , Carcinoma/mortalidade , Carcinoma/psicologia , Seguimentos , Inquéritos Epidemiológicos , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Penianas/mortalidade , Neoplasias Penianas/psicologia , Radiografia , Inquéritos e Questionários , Análise de Sobrevida , Resultado do Tratamento
18.
Rep Pract Oncol Radiother ; 17(3): 122-8, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-24377012

RESUMO

AIM: To evaluate the resources and techniques used in the irradiation of patients with breast cancer after lumpectomy or mastectomy and the status of implementation of new techniques and therapeutic schedules in our country. BACKGROUND: The demand for cancer care has increased among the Spanish population, as long as cancer treatment innovations have proliferated. Radiation therapy in breast cancer has evolved exponentially in recent years with the implementation of three-dimensional conformal radiotherapy, intensity modulated radiotherapy, image guided radiotherapy and hypofractionation. MATERIAL AND METHODS: An original survey questionnaire was sent to institutions participating in the SEOR-Mama group (GEORM). In total, the standards of practice in 969 patients with breast cancer after surgery were evaluated. RESULTS: The response rate was 70% (28/40 centers). In 98.5% of cases 3D conformal treatment was used. All the institutions employed CT-based planning treatment. Boost was performed in 56.4% of patients: electrons in 59.8%, photons in 23.7% and HDR brachytherapy in 8.8%. Fractionation was standard in 93.1% of patients. Supine position was the most frequent. Only 3 centers used prone position. The common organs of risk delimited were: homolateral lung (80.8%) and heart (80.8%). In 84% histograms were used. An 80.8% of the centers used isocentric technique. In 62.5% asymmetric fields were employed. CTV was delimited in 46.2%, PTV in 65% and both in 38.5%. A 65% of the centers checked with portal films. IMRT and hypofractionation were used in 1% and in 5.5% respectively. CONCLUSION: In most of centers, 3D conformal treatment and CT-based planning treatment were used. IMRT and hypofractionation are currently poorly implemented in Spain.

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