[Two cases of stage IIIb breast cancer treated by intra-arterial infusion chemotherapy using implantable reservoir combined with rectus-abdominis musculocutaneous flap reconstruction after mastectomy].

Intra-arterial infusion chemotherapy was performed using implantable reservoir for 2 cases of Stage IIIb breast cancer followed by rectus-abdominis musculocutaneous flap reconstruction after mastectomy. The first case is a 47-year-old female. A total dose of 150 mg ADM was injected via reservoir. After satisfactory local response, mastectomy followed by giant rectus-abdominis musculocutaneous flap reconstruction was performed. The other case is a 64-year-old female. A total dose of 160 mg ADM was injected via reservoir. She was also operated in the same manner as in the first case. Complications of both cases were minimal. It was concluded that this combined treatment was useful for controlling local lesion and sustaining QOL.

[Two cases of stage IV breast cancer with locally advanced lesion treated by intra-arterial infusion chemotherapy using implantable reservoir].

Intra-arterial infusion chemotherapy was used for 2 cases of Stage IV breast cancer with locally advanced lesions using implantable reservoir. The first case is a 64-year-old female who had multiple bone metastases with locally advanced breast lesion. A total dose of 220 mg ADM was injected via reservoir at outpatient department. The other case is a 66-year-old female who had multiple bone metastases with locally advanced breast lesions. A total dose of 235 mg ADM was injected via reservoir. After obtaining satisfactory response of local lesions, a standard radical mastectomy was performed for both cases. It was concluded that this method was useful for controlling locally advanced lesions of Stage IV breast cancer and beneficial for patient QOL.