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1.
J Autism Dev Disord ; 2022 Nov 10.
Artigo em Inglês | MEDLINE | ID: mdl-36357551

RESUMO

This study aims to evaluate the video modeling technique during the dental appointment. A blinded randomized clinical trial was composed of 2 groups, consisting of 20 autistic children (4 to 12 years) in each group: control (did not watch the video before the consultation) and intervention (watched the video before the consultation). The primary outcome was the mean number of visits to perform a dental appointment. The number of consultations was analyzed by T-test or Mann-Whitney test. The results showed that the mean number of consultations in the intervention group was 1.5 (± 1.53) and in the control group 2 (± 1.77) (p ≤ 0.05). The video modeling technique can be effective in minimizing the number of dental consultations in autistic children.

2.
J Evid Based Dent Pract ; 22(3): 101724, 2022 09.
Artigo em Inglês | MEDLINE | ID: mdl-36162888

RESUMO

OBJECTIVE: Burnout syndrome has negative consequences on the dentist's health and performance during work. This systematic review aimed to assess the prevalence of Burnout syndrome in dentists. METHODS: Searches were carried out in Medline, Scopus, Web of Science, PsycINFO, EMBASE, LILACS databases, and searches in the gray literature on January 27, 2021. There were no restrictions on language and search period. For the diagnosis of Burnout, only studies that used the Maslach burnout inventory questionnaire and its subscales emotional exhaustion (EE), depersonalization (DP), and reduced personal accomplishment (PA) were included. Proportion meta-analyses were performed using the Stata 13.0 software. RESULTS: A total of 37 articles were included in the narrative and 31 in quantitative syntheses. The overall prevalence of Burnout syndrome in dentists was 13% (95% confidence interval [CI]: 0.006-0.21; I²: 97.07%) and the total prevalence in the subscales EE, DP, and PA, were, respectively: 28% (95% CI: 0.24-0.32; I²: 20.70%), 18% (95% CI: 0.08-0.28; I²: 85.61%) and 10% (95% CI: 0.08-0.13; I²: 0%). About the levels of Burnout syndrome in the subscales, 25% (95% CI: 0.19-0.31; I² 92.58%) presented high EE, 18% (95% CI: 0.10-0.26; I² 96.62%) high DP and 32% (95% 0.20-0.45; I² 97.86%) low PA. About continuous data, the mean of EE, DP and PA was respectively 17.90 (95% CI: 9.36-26.43; I² 94.8), 6.93 (95% CI: 3.41-10.45; I² 80.2) and, 34.69 (95% CI: 23.82-45.55; I² 98.8). No study presented all the positive criteria of the Joanna Briggs Institute Critical Appraisal checklist. CONCLUSION: In conclusion, there was a considerable prevalence of burnout syndrome in dentists, mainly in the subscale of emotional exhaustion.


Assuntos
Esgotamento Profissional , Esgotamento Psicológico , Esgotamento Profissional/epidemiologia , Esgotamento Profissional/psicologia , Odontólogos , Humanos , Prevalência , Inquéritos e Questionários
3.
J Oral Rehabil ; 49(6): 671-685, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35218239

RESUMO

AIM: To conduct a systematic review and meta-analysis on the prevalence of tooth grinding and/or clenching (TGC) in children and adolescents with a neurodevelopmental disorder or other developmental condition. METHODS: A search was performed in seven databases, two sources of grey literature and reference lists of included studies. Risk of bias was assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Studies Reporting Prevalence Data. We used random-effects models with Freeman-Tukey double arcsine transformation for the meta-analyses. RESULTS: After selection, 77 of the 2240 studies met inclusion criteria and were categorised by disability and type of TGC (reported, clinically observed and definitive). The pooled prevalence of reported TGC in individuals with attention-deficit hyperactivity disorder was 57.6% (95% CI [confidence interval]: 49.5-65.6), 50.4% (95% CI: 35.5-65.4) in individuals with autism spectrum disorder, 67% (95% CI: 59.2-74.8) in cerebral palsy and 68.2% (95% CI: 59.8-76.6) in Down syndrome. Pooled prevalence of clinically observed TGC was 57.5% (95% CI: 31.6-83.4) in autism spectrum disorder and 71.9% (95% CI: 52.4-91.4) in cerebral palsy. Individuals with attention-deficit hyperactivity disorder presented 39.8% (95% CI: 24-55.6) of definitive TGC. CONCLUSION: Prevalence of reported, clinically observed, and definitive TGC varies according to disabilities, although due to high heterogeneity the result should be interpreted with caution. Variations exist mainly due to sampling bias and the use of non-validated methods to assess TGC. CRD42020212640.


Assuntos
Transtorno do Deficit de Atenção com Hiperatividade , Transtorno do Espectro Autista , Bruxismo , Paralisia Cerebral , Transtornos do Neurodesenvolvimento , Adolescente , Transtorno do Deficit de Atenção com Hiperatividade/epidemiologia , Transtorno do Espectro Autista/epidemiologia , Paralisia Cerebral/epidemiologia , Criança , Humanos , Transtornos do Neurodesenvolvimento/epidemiologia , Prevalência
4.
Spec Care Dentist ; 42(4): 369-375, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34856008

RESUMO

AIM: To conduct a bibliometric analysis of the top 100 most-cited papers in dentistry for individuals with neurodevelopmental disorders. METHODS AND RESULTS: A search strategy was constructed and conducted at the Web of Science in the category of "Dentistry, Oral Surgery, and Medicine". The following information was extracted from each paper: title, authorship, year of publication, title of the journal, study subject, study design, age range of sample participants, type of disability, institution, country and continent, number of citations and citation density. Google Scholar and Scopus were used to crosscheck the number of citations of the most-cited papers. The VOSviewer software was used to generate bibliometric network maps. The papers received 4453 citations in Web of Science, ranging from 30 to 106 citations. Most papers were published by the USA (35%), had an observational design (78%) and the main subject was epidemiology (31%). Most studies focused on individuals with Down syndrome (34%) and Autism Spectrum Disorder (18%) and were published in the Journal of Periodontology (10%) and the Pediatric Dentistry Journal (7%). CONCLUSION: Most of the studies included in this review were characterized as epidemiological studies. Future research should focus on behavior guidance, dental education, and access to dental services.


Assuntos
Transtorno do Espectro Autista , Procedimentos Cirúrgicos Bucais , Bibliometria , Criança , Humanos
5.
Spec Care Dentist ; 42(4): 352-360, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34897755

RESUMO

AIMS: This study aimed to report the perception of parents of children/adolescents with autism regarding the parents' fear of the pandemic by COVID-19. Also, to report children's fear about the use of individual protective equipment (IPE) in dental appointments, and the impact on the daily routine during the pandemic. METHODS AND RESULTS: A cross-sectional study through an open online survey was addressed to parents of children/adolescents autistic, aged between 3 and 18 years. The questionnaire had questions regarding the parents' fear of the COVID-19 pandemic, the parents' perception about the children/adolescents' fear of the use of IPEs at dental care, and the impact of the daily routine during the pandemic and social impact after the pandemic. Parents' reports on the degree of ASD (mild, moderate, and severe) of the child/adolescent. A total of 1001 responses were obtained. 50.35% of parents had high fear of the pandemic by COVID-19, 59.34% believe that children/teenagers will be afraid of the dentist's IPE and 61.64% responded that the COVID-19 pandemic had a high impact on the daily routine of children/adolescents with ASD. CONCLUSIONS: Most parents reported fear of the pandemic by COVID-19, that children/adolescents with autism may be afraid of IPE and had a high impact on their daily routine during the pandemic.


Assuntos
Transtorno do Espectro Autista , COVID-19 , Assistência Odontológica para Crianças , Adolescente , Brasil/epidemiologia , Criança , Pré-Escolar , Estudos Transversais , Medo , Humanos , Pandemias , Pais , Inquéritos e Questionários
6.
Sleep Med Rev ; 57: 101468, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-33836485

RESUMO

Sleep bruxism (SB) is a behavior of central origin that is related to different factors. This systematic review aimed to determine the prevalence of clinical signs and symptoms of the masticatory system and their association in children with SB. A structured search in ten databases were taken. Two authors independently selected studies, extracted the data, study quality assessment and graded the evidence. A meta-analysis of proportion and association was performed under random-effect model, confidence interval of 95% and p < 0.05 for pulled values. Were included 22 studies, and their overall quality was poor. The more common clinical signs and symptoms of the masticatory system in children with SB were primary canine wear (P:84.13, 95% CI:78.13-89.32; p = 0.248; I2 25.05), dental wear (P:73.76, 95% CI:38.73-96.91; p < 0.001; I2 97.62) and headache (P:52.85, 95% CI:38.92-66.56; p < 0.001; I2 93.65). The prevalence of SB in children was 31.16% (P:31.16, 95% CI:22.18-40.92; p < 0.001; I2 98.56). There was no significant risk of dental wear and headache in children with SB. There is low to very low certainty of the evidence. The more prevalent clinical signs and symptoms of the masticatory system presented in children with SB were primary canine wear, dental wear and headache. Further studies of high quality are still needed to elucidate these important questions.


Assuntos
Bruxismo do Sono , Criança , Humanos , Prevalência , Bruxismo do Sono/epidemiologia , Sistema Estomatognático
7.
Artigo em Inglês, Português | LILACS, SES-SP | ID: biblio-1136741

RESUMO

ABSTRACT Objective: To investigate the prevalence of self-reported trouble sleeping due to dental problems and its association with oral conditions in schoolchildren. Methods: This is a cross-sectional study carried out with a representative sample of 1,589 schoolchildren aged 8-10 years enrolled in public schools from Florianópolis, Santa Catarina, Brazil. Non-clinical data included a questionnaire about socioeconomic indicators answered by parents/guardians. Children were questioned about whether they had trouble sleeping due to dental problems and about previous history of toothache. Clinical oral examinations were performed to evaluate dental caries - Decayed, Missing, and Filled Teeth Index (DMFT/dmft index) and its clinical consequences [PUFA/pufa index: considering the presence of pulpal involvement (P/p); ulceration of tissues due to tooth fragments from decayed crowns (U/u); fistula (F/f); and abscesses (A/a), and traumatic dental injuries (TDI)]. We conducted a descriptive analysis and used adjusted logistic regression models (p<0.05; 95%CI). Results: The prevalence of trouble sleeping due to dental problems was 28%. Children with untreated dental caries (OR 1.32; 95%CI 1.05-1.67) and clinical consequences from the PUFA/pufa index (OR 1.89; 95%CI 1.45-2.46) had higher chances of reporting trouble sleeping due to dental problems. Conclusions: Approximately one-third of the children declared having trouble sleeping due to dental problems. Untreated dental caries and its clinical consequences were associated with self-reported trouble sleeping due to dental problems in schoolchildren.


RESUMO Objetivo: Investigar a prevalência de problemas para dormir por motivos dentários autorrelatado e sua associação com condições orais adversas em escolares. Métodos: Estudo transversal com amostra representativa de 1589 escolares de 8 a 10 anos matriculados em escolas públicas de Florianópolis, Brasil. Os dados não clínicos incluíram um questionário sobre indicadores socioeconômicos respondidos pelos pais/cuidadores. As crianças foram questionadas se tinham problemas para dormir por motivos dentários e sobre episódios anteriores de dor de dente. Foram realizados exames clínicos orais para avaliar: cárie dentária - Índice de Dentes Cariados, Perdidos e Obturados (índice CPO-D/ceo-d) - e suas consequências clínicas (índice PUFA/pufa - presença de envolvimento pulpar (P/p); ulceração (U/u); fístula (F/f); e abscessos (A/a) e traumatismo dental (TD). Foram realizados análise descritiva e modelos ajustados de regressão logística (p<0,05; IC95%). Resultados: A prevalência de problemas para dormir por motivos dentários foi de 28%. Crianças com cárie dentária não tratada (OR 1,32; IC95% 1,05-1,67) e presença de índice PUFA/pufa (OR 1,89; IC95% 1,45-2,46) apresentaram maiores chances de relatar problemas para dormir devido a razões dentárias. Conclusões: Aproximadamente, um terço das crianças apresentou problemas para dormir devido a razões dentárias. Cárie dentária não tratada e suas consequências clínicas foram associadas a problemas autorrelatados para dormir por motivos dentários em escolares.


Assuntos
Humanos , Masculino , Feminino , Transtornos do Sono-Vigília/epidemiologia , Odontalgia/epidemiologia , Cárie Dentária/epidemiologia , Fatores Socioeconômicos , Estudantes/estatística & dados numéricos , Brasil/epidemiologia , Estudos Transversais , Inquéritos e Questionários , Cárie Dentária/diagnóstico
8.
Rev Paul Pediatr ; 39: e2019342, 2020.
Artigo em Inglês, Português | MEDLINE | ID: mdl-32996996

RESUMO

OBJECTIVE: To investigate the prevalence of self-reported trouble sleeping due to dental problems and its association with oral conditions in schoolchildren. METHODS: This is a cross-sectional study carried out with a representative sample of 1,589 schoolchildren aged 8-10 years enrolled in public schools from Florianópolis, Santa Catarina, Brazil. Non-clinical data included a questionnaire about socioeconomic indicators answered by parents/guardians. Children were questioned about whether they had trouble sleeping due to dental problems and about previous history of toothache. Clinical oral examinations were performed to evaluate dental caries - Decayed, Missing, and Filled Teeth Index (DMFT/dmft index) and its clinical consequences [PUFA/pufa index: considering the presence of pulpal involvement (P/p); ulceration of tissues due to tooth fragments from decayed crowns (U/u); fistula (F/f); and abscesses (A/a), and traumatic dental injuries (TDI)]. We conducted a descriptive analysis and used adjusted logistic regression models (p<0.05; 95%CI). RESULTS: The prevalence of trouble sleeping due to dental problems was 28%. Children with untreated dental caries (OR 1.32; 95%CI 1.05-1.67) and clinical consequences from the PUFA/pufa index (OR 1.89; 95%CI 1.45-2.46) had higher chances of reporting trouble sleeping due to dental problems. CONCLUSIONS: Approximately one-third of the children declared having trouble sleeping due to dental problems. Untreated dental caries and its clinical consequences were associated with self-reported trouble sleeping due to dental problems in schoolchildren.


Assuntos
Cárie Dentária/epidemiologia , Transtornos do Sono-Vigília/epidemiologia , Odontalgia/epidemiologia , Brasil/epidemiologia , Criança , Estudos Transversais , Cárie Dentária/diagnóstico , Feminino , Humanos , Masculino , Fatores Socioeconômicos , Estudantes/estatística & dados numéricos , Inquéritos e Questionários
9.
J Biomed Mater Res B Appl Biomater ; 108(2): 306-315, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-31016876

RESUMO

This study evaluated the biocompatibility of degradable polydioxanone (PDS) electrospun drug delivery systems (hereafter referred as matrices) containing metronidazole (MET) or ciprofloxacin (CIP) after subcutaneous implantation in rats. Sixty adult male rats were randomized into six groups: SHAM (sham surgery); PDS (antibiotic-free matrix); 1MET (one 25 wt% MET matrix); 1CIP (one 25 wt% CIP matrix); 2MET (two 25 wt% MET matrices); and 2CIP (two 25 wt% CIP matrices). At 3 and 30 days, animals were assessed for inflammatory cell response (ICR), collagen fibers degradation, and oxidative profile (reactive oxygen species [ROS]; lipid peroxidation [LP]; and protein carbonyl [PC]). At 3 days, percentages of no/discrete ICR were 100, 93.3, 86.7, 76.7, 50, and 66.6 for SHAM, PDS, 1MET, 1CIP, 2MET, and 2CIP, respectively. At 30 days, percentages of no/discrete ICR were 100% for SHAM, PDS, 1MET, and 1CIP and 93.3% for 2MET and 2CIP. Between 3 and 30 days, SHAM, 1CIP, and 2CIP produced collagen, while 1MET and 2MET were unchanged. At 30 days, the collagen fiber means percentages for SHAM, PDS, 1MET, 1CIP, 2MET, and 2CIP were 63.7, 60.7, 56.6, 62.6, 51.8, and 61.7, respectively. Antibiotic-eluting matrices showed similar or better oxidative behavior when compared to PDS, except for CIP-eluting matrices, which showed higher levels of PC compared to SHAM or PDS at 30 days. Collectively, our findings indicate that antibiotic-eluting matrices may be an attractive biocompatible drug delivery system to fight periodontopathogens. © 2019 Wiley Periodicals, Inc. J Biomed Mater Res Part B, 2019.


Assuntos
Antibacterianos/química , Materiais Biocompatíveis/química , Ciprofloxacina/química , Metronidazol/química , Nanocápsulas/química , Nanofibras/química , Polidioxanona/química , Animais , Antibacterianos/farmacologia , Ciprofloxacina/farmacologia , Liberação Controlada de Fármacos , Humanos , Masculino , Metronidazol/farmacologia , Oxirredução , Implantação de Prótese , Ratos , Espécies Reativas de Oxigênio/metabolismo , Fatores de Tempo , Engenharia Tecidual , Alicerces Teciduais
10.
Eur Arch Paediatr Dent ; 21(5): 573-579, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31808110

RESUMO

AIMS: Assessing the influence of socio-economic characteristics, acid drinking patterns and gastric alterations considering erosive tooth experience in children. METHODS: Cross-sectional study to assess 08-10-year-old children enrolled in the primary education in public schools in Florianopolis, Brazil (n = 1085). Caregivers have answered questionnaires comprising independent variables (head of the household education frequency consumption of sports drinks, acid juice/soda, chewing gum, recurrent vomiting, gastric disorders and vomiting after overeating). Four trained dental surgeons have examined the children for the erosive tooth wear-dependent variable (O'Sullivan index), as well as collected dental caries (DMFT) and dental crowding (DAI index) information. A two-stage cluster-sampling plan was conducted. Unadjusted and adjusted logistic regression models were applied (Odds ratio, OR; 95% Confidence interval, CI and 5% significance level). RESULTS: The prevalence of erosive tooth wear was 15.67%. Erosive tooth wear was positively associated with high consumption of sports drinks (OR 3.42; 95% CI: 1.18-9.23). Children whose caregivers' educational level was equal or less than four years of study were less likely to have erosive tooth wear (OR 0.39; 95% CI: 0.17-0.88). CONCLUSION: High consumption of sports drinks is positively associated with erosive tooth wear. Children whose caregivers' educational level is low are less likely to present erosive tooth wear.


Assuntos
Cárie Dentária , Erosão Dentária/epidemiologia , Erosão Dentária/etiologia , Desgaste dos Dentes , Brasil/epidemiologia , Criança , Estudos Transversais , Humanos , Prevalência , Fatores de Risco , Fatores Socioeconômicos
11.
Artigo em Inglês | BBO - odontologia (Brasil), LILACS | ID: biblio-1135513

RESUMO

Abstract Objective: To analyze whether demographic and socioeconomic factors can influence the OHRQoL in schoolchildren. Material and Methods: A cross-sectional study using a representative sample of 1137 children aged 8-10 years, enrolled in public schools in Florianópolis, Brazil, was conducted. Children answered the Brazilian version of the Child Perceptions Questionnaire (CPQ8-10) quality of life questionnaire and their parents responded to socioeconomic and demographic questions. Logistic regression models were used to analyze the data. Results: Higher probability of presenting a negative impact on the OHRQoL was observed in children whose skin color was non-white (OR 1.46, 95% CI 1.04-1.69) and female (OR 1.33, 95% CI 1.04-1.69). Children in whom the head of the family had years of schooling 9-11 (p=0.001), 5-8 (p=0.005) and ≤4 (p=0.000) were more likely to have a negative impact on the OHRQoL. CPQ8-10 domains evaluation showed that variables education, gender, skin color, and age were associated with a negative impact on OHRQoL (p≤0.05). Conclusion: The educational level of the head of the family and the demographic characteristics of the children are associated with a negative impact on the OHRQoL.


Assuntos
Humanos , Masculino , Feminino , Criança , Qualidade de Vida/psicologia , Fatores Socioeconômicos , Criança , Saúde Bucal/educação , Epidemiologia , Brasil/epidemiologia , Modelos Logísticos , Estudos Transversais/métodos , Inquéritos e Questionários , Disparidades nos Níveis de Saúde
12.
Rev. nav. odontol ; 46(1): 42-47, 20191001.
Artigo em Português, Inglês | LILACS-Express | LILACS | ID: biblio-1533089

RESUMO

A displasia óssea geralmente é um achado radiográfico, por não apresentar, em sua maioria, alterações clínicas. Contudo, um novo subtipo de displasia, que afeta preferencialmente mulheres negras de meia-idade e promove expansão do osso cortical envolvido, tem sido relatada como Displasia Óssea Expansiva. O objetivo deste artigo é relatar dois casos de Displasia Óssea Florida com expressivo aspecto expansivo e perfuração das corticais ósseas envolvidas. O primeiro relata uma paciente negra, 46 anos, que compareceu à Odontoclínica Central da Marinha necessitando de restauração indireta em um dente. O exame clínico demonstrou um aumento de volume duro na face lingual do rebordo alveolar dos incisivos inferiores. Na radiografia panorâmica, foram observadas duas imagens de densidades mistas com predomínio de áreas radiopacas nas regiões apicais dos dentes anteroinferiores e do primeiro molar inferior esquerdo. A tomografia computadorizada mostrou expansão, adelgaçamento da cortical vestibular e perfuração da cortical lingual na região dos incisivos. O segundo caso apresenta uma paciente de meia idade, feoderma, que buscou atendimento para acompanhamento de lesão mista na mandíbula, nas regiões apicais dos dentes anteriores, pré-molares e na região correspondente ao terceiro molar direito. Na tomografia computadorizada por feixe cônico observaram-se expansão e adelgaçamento da cortical vestibular nos dentes anteroinferiores. Com base na literatura atual e nas características de ambas as lesões, a hipótese diagnóstica para ambos os casos foi de Displasia Óssea Florida com aspecto expansivo. As pacientes foram orientadas sobre a importância da higiene bucal adequada e da necessidade de um acompanhamento clínico imagiológico anual destas lesões.


Osseous dysplasia generally is a radiographic finding because, for the most part, it does not cause clinical changes. However, a new subtype of dysplasia that affects primarily middle-aged black women and promotes expansion of the involved cortical bone has been reported as Expansive Osseous Dysplasia. The aim of this article is to report two cases of Florida Osseous Dysplasia with expressive expansion and perforation of the osseous cortex involved. The first case reports a 46-year-old black female patient whom was attended at the Naval Dental Center requiring indirect restoration in one tooth. Clinical examination showed a hard and increased volume at lingual portion of alveolar ridge in the region of the lower incisors. In the panoramic radiography two mixed density images were observed with predominance of radiopaque areas in the apical region of the anterior inferior teeth and in the first lower left molar. The computed tomography showed the buccal cortex thinning and the expansion and perforation of the lingual cortex in the incisor region. The second case presents a middle-aged brown skin patient who sought dental care to monitor a mixed lesion in the apical region of the anterior inferior teeth, lower premolars on both sides and in the third right lower third molar. In cone beam computed tomography, expansion and thinning of the vestibular cortex in the anterior inferior teeth were observed. Based on the current literature and the characteristics of both lesions, the diagnostic hypothesis was Florida Osseous Dysplasia with expansive aspect. The patients were advised on the importance of oral hygiene and the need for an annual follow-up of these lesions

13.
Rev. Saúde Pública Paraná (Online) ; 2(supl. 1): 70-81, jul 19, 2019.
Artigo em Português | CONASS, SESA-PR, Coleciona SUS (Brasil) | ID: biblio-1140645

RESUMO

O presente trabalho teve como objetivo analisar as principais causas de internações hospitalares em idosos de 60 anos ou mais, por regiões do Brasil, em um período de 10 anos. Trata-se de um estudo ecológico, descritivo, utilizando dados secundários provenientes do Sistema de Informações Hospitalares do SUS - SIH/SUS. Para a determinação das causas de internação foram utilizados os capítulos do CID-10. Observou-se que nas cinco regiões brasileiras as principais taxas de internações em idosos ocorreram devido às doenças do aparelho circulatório e do aparelho respiratório. Além disso, nas regiões Norte e Nordeste ainda há uma significativa taxa de internação por algumas doenças infecciosas e parasitárias. (AU)


This study aimed to analyze the leading causes of hospitalization in the elderly aged 60 or more, per regions in Brazil, in a period of 10 years. This is an ecological, descriptive study using secondary data from the Hospital Information System of SUS - SIH / SUS. The ICD-10 chapters were used to determine the causes of hospitalization. It was observed that in the five Brazilian regions the main hospitalization rates among the elderly occurred due to diseases of the circulatory respiratory systems. In addition, in the North and Northeast regions, there is still a significant rate of hospitalization for some infectious and parasitic diseases. (AU)


Assuntos
Humanos , Idoso , Doenças Parasitárias , Classificação Internacional de Doenças , Doenças Transmissíveis , Causalidade , Sistemas de Informação Hospitalar , Serviços de Saúde para Idosos , Hospitalização
14.
RGO (Porto Alegre) ; 66(4): 361-367, Oct.-Dec. 2018. graf
Artigo em Inglês | LILACS | ID: biblio-984919

RESUMO

ABSTRACT Tooth losses due to pathological processes continue to be a reality in daily clinical dentistry, inducing functional and psychological complications in patients. In view of this, a new option for the management of this problem - tissue engineering - has been studied in Dentistry. This field, considered multidisciplinary, uses three key elements for tissue regeneration: scaffolds (extracellular matrices) - natural or synthetic; cells, and growth factors. In this sense, combination of these three elements may induce regeneration of the dental pulp, bone and periodontal tissue, among others. Therefore, the aim of this study was to conduct a literature review, describing the main elements of tissue engineering and their applicability in Dentistry, as a means of updating dental surgeons about this subject.


RESUMO As perdas dentárias, devido aos processos patológicos, ainda são uma realidade na clínica odontológica diária, induzindo complicações funcionais e psicológicas ao paciente. Diante disso, uma nova opção para o manejo desse problema vem sendo estudada na Odontologia, a engenharia tecidual. Essa área, considerada multidisciplinar, utiliza três elementos chaves para a regeneração dos tecidos: os scaffolds (matriz extracelular) naturais ou sintéticos, as células e os fatores de crescimento. Nesse sentido, a combinação desses três elementos pode induzir a regeneração da polpa dentária, tecido ósseo e periodontal, entre outros. Portanto, o objetivo deste estudo é realizar uma revisão da literatura, descrevendo e atualizando os cirurgiões-dentistas sobre os principais elementos da engenharia tecidual e sua aplicabilidade na Odontologia.

15.
Einstein (Sao Paulo) ; 16(2): eAO4248, 2018 Jun 07.
Artigo em Inglês, Português | MEDLINE | ID: mdl-29898090

RESUMO

OBJECTIVE: To evaluate the epidemiological profile and survival rate of oral and oropharyngeal cancer patients seen at a university hospital. METHODS: A cross-sectional study was carried out by means of the pathological reports of patients with oral and oropharyngeal cancer, seen at a university hospital of the Southern Region, between January 2004 and December 2014. Information was collected on patients and tumors. The mortality rate was gathered from the patient death registry in the Mortality Information System. Data were analyzed using the Kaplan-Meier survival curve and the log-rank test to compare variables. RESULTS: The 5- and 10-year survival rates were 42% and 38%, respectively. The anatomical location had a significant association with survival rate (p=0.001), with the rates were better in the lips (p=0.04), and worse in the oropharynx (p=0.03). There were no statistically significant differences between survival rates according to age, sex, ethnicity, schooling level and histologic grade. CONCLUSION: The survival rates of oral and oropharyngeal cancer were and associated with the anatomical site of the tumor.


Assuntos
Neoplasias Bucais/mortalidade , Neoplasias Orofaríngeas/mortalidade , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Brasil/epidemiologia , Estudos Transversais , Feminino , Hospitais Universitários/estatística & dados numéricos , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Bucais/virologia , Neoplasias Orofaríngeas/virologia , Infecções por Papillomavirus/complicações , Prevalência , Fatores de Risco , Análise de Sobrevida , Taxa de Sobrevida
16.
Einstein (Säo Paulo) ; 16(2): eAO4248, 2018. tab, graf
Artigo em Inglês | LILACS | ID: biblio-953165

RESUMO

ABSTRACT Objective To evaluate the epidemiological profile and survival rate of oral and oropharyngeal cancer patients seen at a university hospital. Methods A cross-sectional study was carried out by means of the pathological reports of patients with oral and oropharyngeal cancer, seen at a university hospital of the Southern Region, between January 2004 and December 2014. Information was collected on patients and tumors. The mortality rate was gathered from the patient death registry in the Mortality Information System. Data were analyzed using the Kaplan-Meier survival curve and the log-rank test to compare variables. Results The 5- and 10-year survival rates were 42% and 38%, respectively. The anatomical location had a significant association with survival rate (p=0.001), with the rates were better in the lips (p=0.04), and worse in the oropharynx (p=0.03). There were no statistically significant differences between survival rates according to age, sex, ethnicity, schooling level and histologic grade. Conclusion The survival rates of oral and oropharyngeal cancer were and associated with the anatomical site of the tumor.


RESUMO Objetivo Avaliar o perfil epidemiológico e a taxa de sobrevida do câncer de boca e orofaringe de pacientes atendidos em um hospital universitário. Métodos Foi realizado um estudo transversal por meio dos laudos anatomopatológicos dos pacientes com câncer de boca e orofaringe atendidos em um hospital universitário, na Região Sul, entre janeiro de 2004 a dezembro de 2014. A partir destes laudos, foram coletadas informações sobre o paciente e o tumor. A taxa de mortalidade foi obtida do registro de óbitos dos pacientes no Sistema de Informações sobre Mortalidade. Os dados foram analisados utilizando a curva de sobrevida pelo método de Kaplan-Meier e o teste de log-rank para a comparação das variáveis. Resultados As taxas de sobrevida em 5 e 10 anos foram 42% e 38%, respectivamente. A localização anatômica apresentou associação significativa com a taxa de sobrevida (p=0,001), sendo que, em lábio, os índices foram melhores (p=0,04) e, em orofaringe, piores (p=0,03). Não houve diferenças estatisticamente significantes entre as taxas de sobrevida de acordo com idade, sexo, etnia, nível educacional e grau histológico. Conclusão As taxas de sobrevida do câncer de boca e orofaringe foram baixas e associadas à localização anatômica do tumor.


Assuntos
Humanos , Masculino , Feminino , Adulto , Idoso , Idoso de 80 Anos ou mais , Neoplasias Bucais/mortalidade , Neoplasias Orofaríngeas/mortalidade , Brasil/epidemiologia , Neoplasias Bucais/virologia , Neoplasias Orofaríngeas/virologia , Análise de Sobrevida , Prevalência , Estudos Transversais , Taxa de Sobrevida , Fatores de Risco , Distribuição por Idade , Infecções por Papillomavirus/complicações , Hospitais Universitários/estatística & dados numéricos , Pessoa de Meia-Idade
17.
Rev. colomb. cienc. pecu ; 30(1): 39-47, Jan.-Mar. 2017. tab, graf
Artigo em Inglês | LILACS | ID: biblio-900603

RESUMO

Summary Background: mastectomy in bitches is a critical surgery and pain control can be challenging. Objective: to evaluate the efficacy of pre-emptive analgesia with methadone (MET) or tramadol (TRA) in postoperative pain management, cardiorespiratory effects, and anaesthetic/analgesic consumption in female dogs undergoing ovariohysterectomy (OVH) and mastectomy. Methods: a prospective randomized blind clinical trial was used to evaluate 48 bitches of various breeds, aged 10±3.7 years, weighing 16±12 kg, and with multiple mammary tumours. The animals were distributed in two groups: TRA group received 5 mg/kg tramadol and MET group 0.5 mg/kg methadone intramuscularly, 10 minutes prior to anaesthesia induction with propofol followed by maintenance with isoflurane. Heart (HR) and respiratory (RR) rates, mean arterial pressure (MAP), propofol induction dose (PID), oxyhemoglobin saturation (SpO2), end-tidal isoflurane concentration (EtISO), and carbon dioxide pressure (EtCO2) were measured during the intra-operative period. Post-operative pain was evaluated for 12 hours and rated according to the Melbourne pain scale. Rescue analgesia (0.5 mg/kg methadone, 2 mg/kg lidocaine, or 0.01 mg/kg/min ketamine IV) was given when necessary and post-operative analgesic consumption recorded. Statistical tests were used to compare treatments. Results: rescue analgesia requirements, pain score, PID and analgesic consumption were significantly lower (p<0.05) in MET group. The HR was higher in TRA group, while EtCO2 and MAP were higher in MET group (p<0.05). Conclusions: methadone was more effective than tramadol in pre-emptive analgesia but not completely adequate on controlling pain in bitches subjected to unilateral mastectomy and OVH. MET led to lower cardiovascular depression and lower propofol dose required for anesthesia induction. However, methadone increased EtCO2 and thus special care with patient ventilation is advised.


Resumen Fundamento: la mastectomia en perras es un procedimiento severamente álgido y el control del dolor es un desafío. Objetivo: evaluar la eficacia del tratamiento analgésico preventivo con metadona (MET) o tramadol (TRA) sobre el dolor postoperatorio, parámetros cardiorrespiratorios y consumo de anestésicos en perras sometidas a ovariohisterectomía (OVH) y mastectomía. Métodos: ensayo clínico prospectivo aleatorizado ciego en 48 perras de diversas razas, edad 10±3,7, peso corporal 16±12 kg y con múltiples tumores mamarios. Los animales fueron distribuidos en dos grupos: el grupo TRA recibió 5 mg/kg de tramadol y el grupo MET 0,5 mg/kg de metadona por vía intramuscular 10 minutos antes de inducir anestesia con propofol seguido de mantenimiento con isofluorano. Las variables evaluadas fueron: frecuencia cardíaca (HR), respiratoria (RR), presión arterial media (MAP), dosis de inducción con propofol (PID), saturación de oxihemoglobina (SpO2), concentración de isofluorano (EtISO) y presión de dióxido de carbono (EtCO2) medidos durante el proceso intra-operativo. El dolor postoperatorio fue evaluado de acuerdo con la escala Melbourne durante 12 horas. Analgesia de rescate (metadona 0.5 mg/kg, lidocaína 2 mg/kg, o ketamina 0.01 mg/kg/min IV) se suministró cuando se consideró necesario, y se registró el consumo de analgésico posterior a la cirugia. Se aplicaron pruebas estadísticas para comparar los tratamientos. Resultados: los requerimientos de rescate analgésico, intensidad del dolor, PID y consumo analgésico fueron significativamente menores (p<0,05) en el grupo MET. La HR fue mayor en el grupo TRA, mientras que EtCO2 y MAP fueron mayores en el grupo MET (p<0,05). Conclusiones: la administración preventiva de MET es más eficaz que el tramadol, pero no completamente adecuada para el control del dolor posoperatorio en perras sometidas a mastectomia unilateral y OVH. MET promueve menor depresión cardiovascular y requerimiento de propofol para inducción anestésica. Sin embargo, dado que MET incrementa la EtCO2, se recomienda cuidado especial con la ventilación de estos pacientes.


Resumo Introdução: a mastectomia em cadelas é um procedimento severamente álgido e o controle da dor é um desafio. Objetivo: avaliar a eficácia da analgesia preventiva com metadona ou tramadol sob dor pós-operatória, parâmetros cardiorrespiratórios e consumo anestésico em cadelas submetidas à ovariohisterectomia e mastectomia. Métodos: ensaio clínico prospectivo cego randomizado em 48 cadelas, de diferentes raças, idade 10 ± 3,7 anos, peso 16 ± 12 kg com tumores mamários múltiplos. Os animais foram distribuídos em dois grupos: grupo TRA, tramadol 5 mg/kg e grupo MET, metadona 0,5 mg/kg por via intramuscular, administrados 10 minutos antes da indução anestésica com propofol e manutenção com isofluorano. As variáveis mensuradas foram: frequência cardíaca (FC), respiratória (fR), pressão arterial média (PAM), dose de indução propofol (PID), saturação da oxihemoglobina (SpO2), concentração de isofluorano (EtISO) e pressão de dióxido de carbono (EtCO2) ao final da expiração. A dor pós-operatória foi avaliada durante 12 horas (Escala Melbourne). A necessidade de resgate (metadona 0.5 mg/kg, lidocaína 2 mg/kg, ou cetamina 0.01 mg/kg/min IV) analgésico e o consumo pós-operatório de analgésicos foram registrados. Testes estatísticos foram utilizados para comparar os tratamentos. Resultados: a necessidade de resgate analgésico, escore de dor, PID e o consumo de analgésicos foram menores (p<0,05) no grupo MET. A FC maior no grupo TRA, enquanto EtCO2 e PAM maiores no grupo MET (p<0,05). Conclusões: a administração preventiva de metadona foi mais eficaz, mas não totalmente adequada para o controle da dor pós-operatória do que o tramadol, promovendo redução na depressão cardiovascular e o requerimento de propofol para indução da anestesia. No entanto, a metadona aumentou a EtCO2, recomendando cuidado especial com a ventilação dos pacientes.

18.
Rev. bras. ciênc. vet ; 21(4): 167-172, out.-dez.2014. il.
Artigo em Português | LILACS | ID: biblio-1021003

RESUMO

Avaliaram-se os efeitos nos parâmetros ventilométricos e hemogasométricos em cadelas submetidas à ovário-histerectomia (OHE), pré-medicadas com tramadol ou morfina e anestesiadas com isofluorano. Utilizaram-se 12 cadelas sem raça definida (SRD), divididas em dois grupos (n= 6 para cada grupo), todas com indução anestésica com propofol e manutenção com isofluorano em O2 a 100%, sendo que a diferença entre os grupos se deu pela pré-medicação com tramadol (GT ­ 4mg/kg IM) ou morfina (GM ­ 0,4 mg/kg IM). As observações das variáveis iniciaram-se 30 minutos após a administração do bolus de propofol (M0). As demais colheitas dos dados foram realizadas em intervalos de 15 minutos, por um período de 60 minutos (M15, M30, M45 e M60, respectivamente). Não foram encontradas diferenças significativas entre os grupos ou momentos para as variáveis hemogasométricas, entretanto, as médias de pH, déficit de base (DB) e pressão parcial de dióxido de carbono no sangue arterial (PaCO2 ) ficaram fora da faixa normal para a espécie canina. Foram encontradas diferenças significativas para as variáveis: volume corrente (GM > GT de M0 a M60), pico de fluxo inspiratório e expiratório (GM > GT) e pressão de pico inspiratório, sendo que GM foi maior que GT em M0. Concluiu-se que ambos os opioides são seguros, não causando alterações importantes na ventilometria quando utilizados na pré-medicação em cadelas anestesiadas com isofluorano e submetidas à OHE, porém, a anestesia inalatória com isofluorano deve ser utilizada com cautela em animais com propensão à acidemia.


We evaluated the effects on blood gas and ventilometric parameters in bitches undergoing ovariohysterectomy (OHE), pre-medicated with morphine or tramadol and anesthetized with isoflurane. We used 12 mongrel dogs, distributed into two groups (n = 6 for each group), all with induction of anesthesia with propofol and maintained with isoflurane in 100% O2, and the difference between groups was given by premedication with tramadol (GT - 4mg/kg IM) or morphine (GM - 0.4 mg / kg IM). The measurement of all variables was performed 30 minutes after propofol bolus (M0), and then, in intervals of 15 minutes, during 60 minutes (M15, M30, M45 and M60). No significant differences were found between groups or times for the gas variables, however pH, PaCO2 and DB were outside the normal range for dogs. Significant differences were found for the variables: tidal volume (GM> GT M0 to M60), peak inspiratory and expiratory flow (GM> GT) and peak inspiratory pressure (GM was higher than GT in M0). It was concluded that both opioids are safe and will not cause major changes in ventilometry when used in premedication in dogs anesthetized with isoflurane and submitted to OHE, however, inhalation anesthesia with isoflurane should be used with caution in animals with a tendency to acidemia. .


Assuntos
Animais , Ovário , Tramadol , Gasometria , Analgésicos Opioides , Histerectomia , Isoflurano , Anestésicos , Morfina
19.
Rev. bras. ciênc. vet ; 21(3): 167-172, jul.-set. 2014. tab
Artigo em Português | LILACS, VETINDEX | ID: biblio-1491591

RESUMO

Avaliaram-se os efeitos nos parâmetros ventilométricos e hemogasométricos em cadelas submetidas à ovário-histerectomia (OHE),pré-medicadas com tramadol ou morfina e anestesiadas com isofluorano. Utilizaram-se 12 cadelas sem raça definida (SRD), divididasem dois grupos (n= 6 para cada grupo), todas com indução anestésica com propofol e manutenção com isofluorano em O2 a 100%, sendo que a diferença entre os grupos se deu pela pré-medicação com tramadol (GT – 4mg/kg IM) ou morfina (GM – 0,4 mg/kg IM). As observações das variáveis iniciaram-se 30 minutos após a administração do bolus de propofol (M0). As demais colheitas dos dados foram realizadas em intervalos de 15 minutos, por um período de 60 minutos (M15, M30, M45 e M60, respectivamente). Não foram encontradas diferenças significativas entre os grupos ou momentos para as variáveis hemogasométricas, entretanto, as médias de pH, déficit de base (DB) e pressão parcial de dióxido de carbono no sangue arterial (PaCO2) ficaram fora da faixa normal para a espécie canina. Foram encontradas diferenças significativas para as variáveis: volume corrente (GM > GT de M0 a M60), pico de fluxo inspiratório e expiratório (GM > GT) e pressão de pico inspiratório, sendo que GM foi maior que GT em M0.Concluiu-se que ambos os opioides são seguros, não causando alterações importantes na ventilometria quando utilizados na pré-medicação em cadelas anestesiadas com isofluorano e submetidas à OHE, porém, a anestesia inalatória com isofluorano deve ser utilizada com cautela em animais com propensão à acidemia.


We evaluated the effects on blood gas and ventilometric parameters in bitches undergoing ovariohysterectomy (OHE), pre-medicatedwith morphine or tramadol and anesthetized with isoflurane. We used 12 mongrel dogs, distributed into two groups (n = 6 foreach group), all with induction of anesthesia with propofol and maintained with isoflurane in 100% O2, and the difference betweengroups was given by premedication with tramadol (GT - 4mg/kg IM) or morphine (GM - 0.4 mg / kg IM). The measurement of allvariables was performed 30 minutes after propofol bolus (M0), and then, in intervals of 15 minutes, during 60 minutes (M15, M30,M45 and M60). No significant differences were found between groups or times for the gas variables, however pH, PaCO2 and DBwere outside the normal range for dogs. Significant differences were found for the variables: tidal volume (GM> GT M0 to M60),peak inspiratory and expiratory flow (GM> GT) and peak inspiratory pressure (GM was higher than GT in M0). It was concludedthat both opioids are safe and will not cause major changes in ventilometry when used in premedication in dogs anesthetized withisoflurane and submitted to OHE, however, inhalation anesthesia with isoflurane should be used with caution in animals with atendency to acidemia.


Assuntos
Feminino , Animais , Cães , Gasometria/veterinária , Isoflurano/administração & dosagem , Morfina , Tramadol/análise , Ventilação Pulmonar , Histerectomia/veterinária , Ovariectomia/veterinária
20.
Pesqui. vet. bras ; 34(1): 71-78, jan. 2014. ilus, graf, tab
Artigo em Inglês | LILACS | ID: lil-707115

RESUMO

The overexpression of proteins P-glycoprotein (P-gp), multidrug resistance-associated protein (MRP1), mutant p53, and the enzyme glutathione-S-transferase (GSTpi) are related to resistance to chemotherapy in neoplasms. This study evaluated the expression of these markers by immunohistochemistry in two groups of canine TVT, without history of prior chemotherapy (TVT1, n=9) and in TVTs presented unsatisfactory clinical response to vincristine sulfate (TVT2, n=5). The percentage of specimens positively stained for P-gp, MRP1, GSTpi and p53 were, respectively 88.8%, 0%, 44.5% and 22.2% in TVT1 and 80%, 0%, 80% and 0% in TVT2. In TVT1, one specimen presented positive expression for three markers and four specimens for two markers. In TVT2, three specimens expressed P-gp and GSTpi. In conclusion, the canine TVTs studied expressed the four markers evaluated, but just P-gp and GSTpi were significantly expressed, mainly at cytoplasm and cytoplasm and nuclei, respectively, either before chemotherapy as after vincristine sulfate exposure. Future studies are needed to demonstrate the function of these two markers in conferring multidrug resistance (MDR) or predict the response to chemotherapy in canine TVT.


A superexpressão das proteínas glicoproteína-P (Gp-P), proteína associada à resistência à múltiplas drogas 1 (MRP1) e p53 mutante e a enzima glutationa-S-transferase pi (GSTpi) está relacionada com resistência à quimioterapia em neoplasias humanas e caninas. Este estudo avaliou a expressão, por meio da imuno-histoquímica desses marcadores em espécimes de TVT caninos sem histórico de quimioterapia prévia (TVT1, n=9) e em TVT caninos que apresentaram resposta clínica insatisfatória ao sulfato de vincristina (TVT2, n=5). A porcentagem de espécimes positivos para Gp-P, MRP1, GSTpi e p53 foram, respectivamente 88,8%, 0%, 44,5% e 22,2% no grupo TVT1 e 80%, 0%, 80% e 0% no grupo TVT2. No TVT1, um espécime apresentou expressão positiva para três marcadores e quatro para dois marcadores. No TVT2, três espécimes expressaram a Gp-P e GSTpi. Em conclusão, os TVTs caninos estudados expressaram os quatro marcadores avaliados, no entanto apenas a Gp-P e GSTpi foram significativamente expressas, principalmente no citoplasmas e no citoplasma e no núcleo, respectivamente, tanto antes da quimioterapia quanto após à exposição ao sulfato de vincristina. Estudos futuros são necessários para demonstrar a função desses dois marcadores em conferir resistência à multiplas drogas (RMD) ou predizer a resposta a quimioterapia no TVT canino.


Assuntos
Animais , Cães , Cães/metabolismo , Resistencia a Medicamentos Antineoplásicos , Tumores Venéreos Veterinários/química , Vincristina/administração & dosagem , Glutationa , Imuno-Histoquímica/veterinária , Subfamília B de Transportador de Cassetes de Ligação de ATP
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