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Rev Esp Quimioter ; 28(4): 193-9, 2015 Aug.
Artigo em Espanhol | MEDLINE | ID: mdl-26200027

RESUMO

OBJECTIVE: To evaluate reports of adverse events following influenza immunization by sex, risk and age groups in Valencian Community from 2005 to 2011. METHODS: A pharmacoepidemiological descriptive cross-sectional observational study based on the reports of adverse events following immunization (AEFI) against influenza, registered through the Vaccination Information System (SIV) of Valencian Community from 1 January 2005 until 31 December 2011 was done. RESULTS: During the study period 5,107,790 doses of vaccine against influenza were reported, with an AEFI incidence of 1.94 per 100,000 (95% CI 1.59 to 2.36), and 228,094 doses of vaccine for influenza A (H1N1) pdm09 (96.45 per 100,000, 95%CI 84.52-110.06). The 70.71% (70) and 64.55% (142), respectively, of AEFI were in women. The healthcare workers group had a higher reporting rate for seasonal influenza (25.35 per 100,000; 95%CI: 17.65-36.40) and for influenza A(H1N1) pdm09 (864.13 per 100,000; 95%CI 714.38-1044.93) during the study period. CONCLUSIONS: Vaccines against influenza administered during the study had a high safety profile in both populations with disease risk and other susceptible target groups of vaccination. Adverse reactions reported during the study mostly coincide with those described in the summary of product characteristics of vaccines.


Assuntos
Vacinas contra Influenza/efeitos adversos , Adolescente , Adulto , Distribuição por Idade , Idoso , Criança , Doença Crônica/epidemiologia , Estudos Transversais , Eritema/etiologia , Fadiga/etiologia , Feminino , Pessoal de Saúde/estatística & dados numéricos , Humanos , Hospedeiro Imunocomprometido , Masculino , Pessoa de Meia-Idade , Obesidade Mórbida/epidemiologia , Exposição Ocupacional , Dor/etiologia , Gravidez , Risco , Distribuição por Sexo , Espanha/epidemiologia , Populações Vulneráveis/estatística & dados numéricos , Adulto Jovem
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