RESUMO
Lentigo maligna (LM) is usually diagnosed in sun-damaged skin of elderly patients and a correct excision of the lesion determines a complete healing from the disease. LM is very rare in young patients and, for this reason, it can be commonly misdiagnosed. We describe the case of a locally recurrent LM in a 19-year-old male patient, which initially arose at the age of 17 years. In order to avoid diagnostic pitfalls, clinicians have to put more emphasis on diseases which previously were prerogative only of elderly patients and that now could begin to engage a younger age, according to climate and behavior changes.
Assuntos
Sarda Melanótica de Hutchinson , Neoplasias Cutâneas , Adolescente , Adulto , Idoso , Humanos , Sarda Melanótica de Hutchinson/diagnóstico , Masculino , Neoplasias Cutâneas/diagnóstico , Adulto JovemAssuntos
Dermoscopia , Neoplasias Faciais/patologia , Melanoma/patologia , Neoplasias Cutâneas/patologia , Idoso , Biomarcadores Tumorais/análise , Neoplasias Faciais/irrigação sanguínea , Neoplasias Faciais/química , Neoplasias Faciais/diagnóstico por imagem , Humanos , Masculino , Melanoma/irrigação sanguínea , Melanoma/química , Melanoma/diagnóstico por imagem , Neoplasias Cutâneas/irrigação sanguínea , Neoplasias Cutâneas/química , Neoplasias Cutâneas/diagnóstico por imagemAssuntos
Fármacos Dermatológicos/administração & dosagem , Ceratoacantoma/tratamento farmacológico , Ácidos Nicotínicos/administração & dosagem , Administração Cutânea , Idoso , Idoso de 80 Anos ou mais , Feminino , Géis , Humanos , Ceratoacantoma/fisiopatologia , Pessoa de Meia-Idade , Resultado do TratamentoRESUMO
Pathologists who find ectopic glands on the glans and/or on the prepuce, often describe them as Tyson's glands. In this regard, the term Tyson's glands can be replaced by two different descriptive expressions: papillomatosis corona penis and ectopic sebaceous glands. A 15-year-old Caucasian male patient presented to our Institute with multiple and asymptomatic circular skin colored-to-yellowish papules at the level of the foreskin, also affecting the shaft of the penis, where they assumed a linear feature. The histological examination revealed hyperplastic and dilated sebaceous glands, while in some areas these glands showed also a direct attachment with the epidermis. A lymphocytic infiltrate was also observed in one of the two specimens. A final diagnosis of linear ectopic sebaceous hyperplasia of the penis was made. According to the current report, the ectopic sebaceous hyperplasia of the penis can have a circular and a linear patter, as well as the presence and the absence of a lymphoid infiltrate. A correct clinical and pathological diagnosis are necessary to avoid unnecessary treatments and worries in the patients. In fact, not infrequently, this condition is confused with dermatological diseases as molluscum contagiosum, epithelioid granuloma, lymphangioma circumscriptum, multiple syringomas, lichen planus, and bowenoid papulosis.
Assuntos
Prepúcio do Pênis/patologia , Doenças do Pênis/diagnóstico , Glândulas Sebáceas/patologia , Adolescente , Diagnóstico Diferencial , Humanos , Hiperplasia/patologia , Masculino , Doenças do Pênis/patologiaRESUMO
BACKGROUND: The association of multiple cutaneous granular tumors with systemic defects is extremely rare. To date, 14 cases have been described. CASE REPORT: A 14-year-old boy presented multiple nodular lesions on his arms and legs; facial dysmorphism and joint hypermobility were also present. Histopathologic examination of two nodules showed granular cell tumors. We review the literature regarding multiple granular cell cutaneous tumors in children with associated somatic defects and genetic syndromes. CONCLUSIONS: The combination of multiple cutaneous granular tumors with alterations in other organs is not only fortuitous, justifying the proposal of a distinct syndrome, termed "Bakos's syndrome" after the author who first described this association. The relation with neurofibromatosis type 1 is discussed, and an association is suggested with the range of variants of this syndrome.
Assuntos
Anormalidades Craniofaciais/complicações , Tumor de Células Granulares/complicações , Instabilidade Articular/complicações , Neoplasias Cutâneas/complicações , Adolescente , Anormalidades Craniofaciais/patologia , Tumor de Células Granulares/patologia , Humanos , Instabilidade Articular/patologia , Masculino , Neoplasias Cutâneas/patologiaRESUMO
Follicular mucinosis has a protean clinical presentation and can be differentiated in a benign-idiopathic type and an evolutive lymphoma-associated type. Young age and single localization, especially in the head and neck region, are suggestive of the benign type. Reviewing the literature of follicular mucinosis appearing as an acneiform eruption of the face and neck, we were unable to find any case evolving in lymphoma, suggesting that this form is a particular clinical sub-type of follicular mucinosis with a favorable prognosis. We report two cases of this variant of follicular mucinosis and discuss the clinical characteristics and differential diagnosis.