RESUMO
We report two cases of the rare occurrence of prostatic epithelium in ovarian teratomas with associated transitional epithelium in one of the cases. This association of prostatic tissue with urothelium tends to reinforce the well-established embryogenetic derivation of the prostate from the urogenital sinus. Local hormonal events may influence the formation of prostatic tissue from female urothelium. The histologic and immunohistological differences between adult prostate as seen in our cases and female paraurethral (Skene's) glands are discussed.
Assuntos
Cisto Dermoide/patologia , Neoplasias Ovarianas/patologia , Adulto , Feminino , Humanos , Masculino , Próstata/patologiaRESUMO
Teratomas occur infrequently in retroperitoneal areas and are usually benign. They may contain highly organized structures like digits and limbs. The presence of a well-formed fetus in teratomas is extremely rare. This report further documents an instance in which two fetuses were embedded within the retroperitoneal teratoma.
Assuntos
Neoplasias Peritoneais/patologia , Teratoma/patologia , Feminino , Feto , Humanos , Recém-Nascido , Rim/cirurgia , Neoplasias Peritoneais/cirurgia , Teratoma/cirurgiaRESUMO
Thirty-three random biopsy specimens of uterine cervix were studied by immunoperoxidase technique to evaluate the presence of HPV antigen in dysplastic and neoplastic cells. Four cases of mild dysplasia, nine cases of moderate to severe dysplasia, two cases of carcinoma in situ and one case of invasive carcinoma were associated with condylomatous lesions. Intranuclear dark-brown precipitates were observed in superficial and intermediate zones of the dysplastic epithelium. Positive reaction was seen in condylomatous epithelium associated with neoplasia. No nuclear precipitates were observed in carcinoma cells, but one noncondylomatous lesion with moderate dysplasia showed positive intranuclear staining. These preliminary findings suggest that papilloma viruses may play a role in the development of human cervical neoplasias.