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1.
Artigo em Inglês | MEDLINE | ID: mdl-17466884

RESUMO

On the mandibular reconstruction after tumor resection, it is easy to achieve esthetic and functional results when mandibular defect is relative small, however, it is difficult to reconstruct adequately larger defected mandible. Recently, with progress of devices, distraction osteogenesis that is the method of tissue regeneration is used as mandibular reconstruction. A 19-year-old male patient presented complaining of right lower jaw swelling. Biopsy suspected a multiple-cystic ameloblastoma in mandible. Under the general anesthesia, a mandibulectomy was performed from the right side ramus to the left side incisor. A mandibular reconstruction plate was attached to the proximal and distal bone segments. 2 types of intraoral distraction devices were placed inside the plate. These devices had 25 mm and 60 mm distraction length. After 9 days of latency, trifocal bone transport was started by 0.5 mm 2 times activation per day. After consolidation for 23 weeks, reconstruction plate and distraction devices were removed. 2.5 m x 2.0 cm iliac bone and cancellous bone were placed in the docking site with platelet rich plasma. The mandibular defect (85 mm) was reconstructed adequately using intraoral distraction osteogenesis trifocal bone transport technique. Symmetric facial balance was achieved. Now there is no recurrence and dental implants were placed on new bone.


Assuntos
Ameloblastoma/cirurgia , Mandíbula/cirurgia , Neoplasias Mandibulares/cirurgia , Procedimentos Cirúrgicos Bucais/métodos , Osteogênese por Distração/métodos , Procedimentos de Cirurgia Plástica/métodos , Adulto , Ameloblastoma/reabilitação , Transplante Ósseo , Calo Ósseo/fisiologia , Implantação Dentária Endóssea , Humanos , Masculino , Neoplasias Mandibulares/reabilitação , Osteogênese por Distração/instrumentação
2.
Gan To Kagaku Ryoho ; 33(13): 2041-3, 2006 Dec.
Artigo em Japonês | MEDLINE | ID: mdl-17197749

RESUMO

A 53-year-old man underwent partial glossectomy for tongue cancer on the right side (well-differentiated squamous cell carcinoma T 1 N 0 M 0). One and 9 months later, cervical lymph node metastasis was observed bilaterally. After bilateral radical neck dissection, 2 courses of NDP/5-FU combined chemotherapy were administered. However, 2 metastatic lung cancers were observed 14 months after initial treatment. Stereotactic radiation therapy of 50 Gy in 5 fractions and 6 courses of docetaxel/cisplatin/5-FU chemotherapy were administered. As a result, no recurrence was observed, and a complete response was obtained for 41 months after lung metastasis.


Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Carcinoma de Células Escamosas/secundário , Neoplasias Pulmonares/tratamento farmacológico , Neoplasias Pulmonares/radioterapia , Neoplasias da Língua/patologia , Carcinoma de Células Escamosas/cirurgia , Cisplatino/administração & dosagem , Terapia Combinada , Docetaxel , Esquema de Medicação , Fluoruracila/administração & dosagem , Humanos , Neoplasias Pulmonares/secundário , Metástase Linfática , Masculino , Pessoa de Meia-Idade , Esvaziamento Cervical , Dosagem Radioterapêutica , Indução de Remissão , Taxoides/administração & dosagem , Neoplasias da Língua/cirurgia
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