O desamparo em Freud e a política como ruptura dos possíveis / Helplessness in Freud and politics as a rupture of the possible / Le délaissé chez Freud et la politique comme rupture du possible / Lo desamparo en Freud y la política como ruptura de lo posible

Este trabalho visa delinear o conceito de desamparo por meio da metapsicologia freudiana e como isso implica outra forma de pensar a política. Desse modo, o desamparo não é concebido unicamente como a vulnerabilidade do bebê ao nascer, mas, também, como a falta de respostas às excitações internas. Tal estado de desamparo é radicalizado a partir da concepção de pulsão de morte construída por Freud. A pulsão de morte gera processos de desabamentos, rupturas, desligamentos e despossessão, essenciais para a própria vida se complexificar. Nesse sentido, propomos o desamparo como afeto político central quando pensamos em transformação. A partir do desabamento de si e da abertura radical ao contato do outro, podemos experimentar outras formas de experiências, outras formas de afetação e, consequentemente, a construção de corpos políticos rumo à transformação política radical

This paper outlines the concept of helplessness through Freudian metapsychology and by doing so imply a new way of thinking about politics. Helplessness is not conceived simply as the newborn's vulnerability, but also as the lack of response to internal excitements. Such an estate is radicalized by Freud's concept of death drive, which generates processes of collapsing, ruptures, unplugging and dispossession that are essential for turning life complex. In this sense, we propose helplessness as a main political affection when referring to transformation. By the collapse of oneself and the radical opening to contact with others, one may experience other ways of experiencing and of being affected and, consequently, the construction of political bodies leading to the radical transformation of politics

Cet article présente le concept de délaissé à travers la métapsychologie freudienne et, ce faisant, lui imprime une nouvelle façon de penser la politique. Le délaissé n'est pas simplement conçu comme la vulnérabilité du nouveau-né, mais aussi comme une absence de réponse aux excitations internes. Tel état est radicalisé par le concept de pulsion de mort de Freud, qui produit des processus de glissement, de rupture, d'arrêt et de dépossession essentielles à la complexification de la vie. En ce sens, nous proposons le délaissé comme principale affection politique lorsqu'il est question de transformation. Par le glissement de soi-même et l'ouverture radicale au contact avec les autres, nous pouvons expérimenter d'autres façons de vivre et d'être affecté et, par conséquent, la construction de corps politiques vers à la transformation politique radicale

Este artículo pretende esbozar el concepto de desamparo a través de la metapsicología freudiana y cómo esto implica otra forma de pensar sobre política. De esa manera, la impotencia no solo se concibe como la vulnerabilidad del bebé al nacer, sino también debido a la falta de respuestas a las excitaciones internas. Tal estado de desamparo se radicaliza desde la concepción del impulso de muerte construido por Freud. El impulso de la muerte genera procesos de colapsos, rupturas, desconexiones y desposesión esenciales para que la vida misma se vuelva más compleja. En este sentido, proponemos lo desamparo como un afecto político central cuando pensemos en la transformación. Desde el colapso de uno mismo y la apertura radical al contacto con el otro, podemos experimentar otras formas de experiencias y otras formas de afectación y,en consecuencia, la construcción de cuerpos políticos hacia una transformación política radical

Predicting the future of threatened birds from a Neotropical ecotone area.

Climate change affects ecosystems in different ways. These effects are particularly worrying in the Neotropical region, where species are most vulnerable to these changes because they live closer to their thermal safety limits. Thus, establishing conservation priorities, particularly for the definition of protected areas (PAs), is a priority. However, some PA systems within the Neotropics are ineffective even under the present environmental conditions. Here, we test the effectiveness of a PA system, within an ecotone in northern Brazil, in protecting 24 endangered bird species under current and future (RCP8.5) climatic scenarios. We used species distribution modeling and dispersal corridor modeling to describe the priority areas for conservation of these species. Our results indicate that several threatened bird taxa are and will potentially be protected (i.e., occur within PAs). Nonetheless, the amount of protected area is insufficient to maintain the species in the ecotone. Moreover, most taxa will probably present drastic declines in their range sizes; some are even predicted to go globally extinct soon. Thus, we highlight the location of a potentially effective system of dispersal corridors that connects PAs in the ecotone. We reinforce the need to implement public policies and raise public awareness to maintain PAs and mitigate anthropogenic effects within them, corridors, and adjacent areas, aiming to conserve the richness and diversity of these already threatened species.

Humidity-insensitive optical fibers for distributed sensing applications.

Humidity is a critical environmental factor in various applications, and its temperature dependence must be considered when developing thermo-hygrometer fiber sensors. The optical fibers that constitute the sensor must have a temperature reference, which should be resistant to humidity to avoid cross-sensitivities. This paper presents two innovative optical fibers insensitive to humidity over temperatures ranging from -20∘ C to 55°C. To the best of our knowledge, the novel standard size optical fibers coated with acrylate and silicone are tested under controlled conditions using an optical time-domain reflectometer sensor based on Rayleigh scattering. The sensor achieves meter-range resolution over kilometers of length with a response time of few minutes.

Are men more likely to have serious occupational accidents? Findings of reported cases in Palmas, northern Brazil.

To ascertain whether male workers from Palmas, Tocantins state, northern Brazil, are more likely to have occupational accidents compared to female workers, all cases of serious occupational accidents reported between 2009 and 2019 were extracted from the Brazilian Notifiable Diseases Information System and compared with the economically active population according to sex. Men were found to be 6.2 times more likely to have a serious occupational accident compared to women. Therefore, reviewing occupational health and safety policies in predominantly male workplaces is necessary.

Para averiguar se trabalhadores do sexo masculino de Palmas, no estado do Tocantins, são mais propensos a terem acidentes de trabalho comparados com as do sexo feminino, foram extraídos do Sistema de Informação de Agravos de Notificação os casos de acidentes de trabalho graves notificados entre 2009 e 2019 e comparados com a população economicamente ativa de acordo com o sexo. Foi constatado que os homens apresentam 6,2 vezes mais chances de sofrerem um acidente de trabalho grave comparados com as mulheres. Portanto, é necessário rever as políticas de saúde e segurança do trabalhador nos ambientes de trabalho majoritariamente masculinos.

Sofrimento psíquico no neoliberalismo e a dimensão política do diagnóstico em saúde mental / Psychic suffering in neoliberalism and the political dimension of the mental health diagnosis

Resumo Este trabalho objetiva demonstrar a dimensão política do diagnóstico das formas de sofrimento psíquico, a partir da crítica da racionalidade neoliberal. A metodologia utilizada foi o trabalho de um conceito através de revisão de bibliografias, principalmente da Psicopatologia e Teoria Social. Historicamente, o tratamento clínico e social dado aos sujeitos que apresentam algum tipo de sofrimento psíquico se relaciona com a cultura de cada época e com a forma vigente de se exercer o poder. Na modernidade, o paradigma psiquiátrico acerca das doenças mentais segue a lógica do dispositivo saber-poder biomédico, que, dentro da lógica neoliberal individualizante, responsabiliza cada sujeito por seu adoecimento e tem como máxima o autoaprimoramento, não a cura. Nesse sentido, as categorias diagnósticas de nossa época servem muito mais para capturar as formas hegemônicas de mal-estar e traduzir em uma gramática passível de normalização do que para expressar a natureza de uma doença mental. Tal hipótese tem imenso peso político, visto que uma razão diagnóstica totalizante corrobora para o esgotamento da capacidade de enfrentar conflitos, contradições e reinvenções, o que gera um cenário de dificuldades para lidar com a alteridade e com as contingências próprias da vida, que acabam sendo patologizadas.

Abstract This work aims to demonstrate the political dimension of the diagnosis of the forms of psychic suffering, from the critique of neoliberal rationality. The methodology used was the work of a concept with a review of bibliographies, mainly on psychopathology and social theory. Historically, the clinical and social treatment given to subjects who present some type of psychic suffering is related to the culture of each time and the current way of exercising power. In modernity, the psychiatric paradigm about mental illness follows the logic of the biomedical knowledge-power device, which, within the individualizing neoliberal logic, holds each subject responsible for their illness and has at its maximum the self-improvement and not the cure. In this sense, the diagnostic categories of our time serve much more to capture the hegemonic forms of malaise and translate them into a grammar that can be normalized than to express the nature of a mental illness. Such a hypothesis has immense political weight, since a totalizing diagnostic reason corroborates the exhaustion of the capacity to deal with conflicts, contradictions, and reinventions, which generates a scenario of difficulties in coping with alterity and with the contingencies of life, which end up being pathologized.

Profile of victims of occupational accidents involving exposure to biological material notified in the city of Palmas, state of Tocantins, Brazil.

Introduction: An occupational accident involving exposure to biological material is characterized by worker's contact with organic fluids during the working day and in Brazil it is considered a condition of compulsory declaration. Objectives: To analyze the profile of victims of occupational accident involving exposure to biological material in the city of Palmas, state of Tocantins, from 2010 to 2020. Methods: Descriptive cross-sectional study using the Notifiable Diseases Information System. Results: During the study period, there were 1,173 notifications, most of which were female (80.10%), aged from 20 to 49 years (90.20%), and worked as statutory civil servants (44.50%). Percutaneous exposure was the most common type of accident, and blood was the main route of contamination (81.59%). Most victims evolved with discharge without serological conversion (66.92%), and 18.5% withdrew follow-up. The most frequent circumstance was improper disposal on the floor (12.45%). Health care professionals were the most involved in occupational accidents with biological material (79.02%) compared with professionals from other areas, with a predominance of nursing professionals (60.35%). Conclusions: The findings of this study reiterate training in the prevention of occupational accidents involving exposure to biological material is necessary for all jobs involving exposure to this type of material, regardless of the area, as well as changes in work organization so as to reduce the presence of risk factors for this type of injury.

Introdução: O acidente de trabalho com exposição a material biológico caracteriza-se pelo contato do trabalhador com fluidos orgânicos durante a jornada laboral, sendo no Brasil considerado um agravo de notificação compulsória. Objetivos: Analisar o perfil das vítimas de acidente de trabalho com exposição a material biológico no município de Palmas, estado do Tocantins, entre os anos de 2010 e 2020. Métodos: Estudo descritivo de caráter transversal realizado utilizando dados do Sistema de Informação de Agravos de Notificação. Resultados: Nesse período houve 1.173 notificações, sendo a maioria das vítimas do sexo feminino (80,10%), com idade entre 20 e 49 anos (90,20%), e grande parte servidores públicos estatutários (44,50%). O acidente com exposição percutânea foi o tipo mais comum, sendo o sangue a principal via de contaminação (81,59%). A maioria das vítimas evoluíram com alta sem conversão sorológica (66,92%), e 18,5% abandonaram o acompanhamento da evolução. A circunstância mais frequente foi o descarte inadequado no chão (12,45%). Os profissionais de saúde foram os mais acometidos por acidentes de trabalho com material biológico (79,02%) em comparação com profissionais de outras áreas, com predomínio da categoria da enfermagem (60,35%). Conclusões: Os achados do presente estudo reiteram que a capacitação para a prevenção de acidentes de trabalho com exposição a material biológico se faz necessária a todas as funções com exposição a tal material, independentemente da área, bem como mudanças na organização do trabalho no intuito de reduzir a presença de fatores de risco para esse tipo de agravo.

Coxiella burnetii in Dogs and Cats from Portugal: Serological and Molecular Analysis.

Dogs and cats are potential sources of infection for some zoonotic diseases such as Q fever, caused by Coxiella burnetii, a multiple host pathogen. Q fever outbreaks in dogs and cats have been related with parturition and abortion events, and ticks have a potential role in the transmission of this pathogen. This study aimed to screen for C. burnetii in dogs and cats, and in ticks collected from infested animals. An observational descriptive study was conducted in Portugal at two time points nine years apart, 2012 and 2021. Sera obtained from dogs and cats (total n = 294) were tested for C. burnetii antibodies using a commercial ELISA adapted for multi-species detection. C. burnetii DNA was screened by qPCR assay targeting IS1111 in uterine samples and in ticks. A decrease in the exposure to C. burnetii was observed in cats from 17.2% (95% CI: 5.8−35.8%) in 2012 to 0.0% in 2021, and in dogs from 12.6% (95% CI: 7.7−19.0%) in 2012 to 1.7% (95% CI: 0.3−9.1%) in 2021 (p < 0.05). Overall, and despite differences in the samples, rural habitat seems to favour the exposure to C. burnetii. The DNA of C. burnetii was not detected in ticks. The low seropositivity observed in 2021 and the absence of C. burnetii DNA in the tested samples, suggest that dogs and cats from Portugal are not often exposed to the pathogen. Nevertheless, the monitoring of C. burnetii infection in companion animals is an important tool to prevent human outbreaks, considering the zoonotic potential for owners and veterinarians contacting infected animals, mainly dogs and cats from rural areas which often come into contact with livestock.

Risk factors for stress in professionals at the North emergency care unit in Palmas, Tocantins, Brazil.

Introduction: Emergency care units provide intermediate complexity care services, are open 24 hours a day, and are frequently required to attend to high levels of demand, especially so during the Covid-19 pandemic. On-duty shift work at emergency care units is highly conducive to causing excessive stress. Objectives: To identify the risk factors for excessive stress among workers at the North emergency care unit, in Palmas, Tocantins, Brazil. Methods: A questionnaire was administered covering basic information and data on lifestyle to the workers at the unit, in addition to the Epworth Sleepiness Scale and a single-item instrument for diagnosis of stress. Results: It was possible to recruit 44 participants. It was observed that 57% of the participants exhibited stress and 31.82% had excessive sleepiness. Having more than one job, drinking alcohol, having attended higher education, and having excessive sleepiness increased the likelihood of exhibiting stress. There was a statistical significant association of very large magnitude between performing housework and exhibiting symptoms of stress (p = 0.028; rɸ = 0.36). Conclusions: The high percentage of workers with stress found among the study participants reveals a need for measures to review their working processes, such as creating space for dialogue between workers and management or implementing shared management, with the objective of minimizing development of work-related disorders, with benefits both for the workers and the Unit.

Introdução: As unidades de pronto atendimento prestam serviços de complexidade intermediária, operando em regime de plantão (24 horas) e atendendo frequentemente a altas demandas, especialmente no período da pandemia por covid-19. Serviços de pronto atendimento em regime de plantão são muito propícios a produzir estresse excessivo em seus trabalhadores. Objetivos: Verificar quais são os fatores de risco para estresse excessivo entre trabalhadores da unidade de pronto atendimento Norte, em Palmas, Tocantins. Métodos: Foi aplicado um questionário acerca de informações básicas e de estilo de vida dos trabalhadores dessa unidade, além da Escala de Sonolência de Epworth e um instrumento de um único item para diagnóstico do estresse. Resultados: Foi possível obter a adesão de 44 participantes. Constatou-se que 57% dos participantes apresentavam estresse, e 31,82% apresentavam sonolência diurna excessiva. Ter duplo vínculo, ser etilista, ser profissional de nível superior e ter sonolência diurna excessiva aumentaram as chances de apresentar estresse. Houve associação estatística significativa e de muito alta magnitude entre realizar tarefas domésticas e apresentar sintomas de estresse (p = 0,028; rɸ = 0,36). Conclusões: O alto percentual de servidores com estresse encontrado entre os participantes suscita medidas de revisão do processo de trabalho, tais como promover espaços de diálogo entre servidores e gestores ou promover gestão compartilhada, no intuito de minimizar o desenvolvimento de transtornos relacionados ao trabalho e beneficiar tanto os servidores quanto o próprio Serviço.

Patologia do desempenho: TDAH, drogas estimulantes e formas de sofrimento no capitalismo / Performance pathology: ADHD, stimulant drugs, and forms of suffering in the capitalism / Patología de desempeño: TDAH, drogas estimulantes y formas de sufrimiento en el capitalismo

O consumo de medicamentos estimulantes cresceu nos últimos anos, no Brasil e no mundo. Pessoas de diferentes idades, especialmente crianças e adolescentes, passaram a consumir estimulantes como a principal terapêutica utilizada para tratar o transtorno do déficit de atenção e hiperatividade (TDAH). Nesse contexto, estimulantes como as anfetaminas e o metilfenidato, mais conhecidos pelos nomes comerciais de Adderall e Ritalina, ganharam visibilidade social em razão da associação desses psicofármacos ao aperfeiçoamento de funções psíquicas como a atenção e o aumento na qualidade e no tempo de rendimento dos sujeitos nas mais variadas atividades. Com isso, aumentou também a procura desses estimulantes por pessoas que não estão em tratamento médico, mas que buscam aprimorar seu desempenho nas atividades que realizam. Diante desse cenário, o objetivo deste artigo foi demonstrar como o crescimento no consumo de estimulantes, seja por sujeitos em tratamento médico ou não, está relacionado aos processos de socialização hegemônicos nas sociedades capitalistas atualmente. Articulando o contexto apresentado com os conceitos da psicanálise lacaniana, foi possível concluir que o consumo massivo de estimulantes está relacionado aos processos de patologização e medicalização da existência, colocados em movimento por uma articulação entre o discurso médico-científico e o discurso do capitalista na contemporaneidade.(AU)

The consumption of stimulating drugs has grown in recent years in Brazil and worldwide. People of all ages, especially children and adolescents, started to use stimulants as the main therapy used to treat attention deficit hyperactivity disorder (ADHD). In this context, stimulants such as amphetamines and methylphenidate, better known by the trade names Adderall and Ritalin, have gained social visibility due to the association of these psychoactive drugs with the improvement of psychic functions such as attention and the increase in quality and performance time of subjects in the most varied activities. As a result, the demand for these stimulants has also increased by people who are not undergoing medical treatment, but who seek to improve their performance in the activities they perform. Given this scenario, this article aimed to demonstrate how the growth in the consumption of stimulants, whether by subjects undergoing medical treatment or not, is related to the hegemonic socialization processes in capitalist societies today. Articulating the context presented with the concepts of Lacanian psychoanalysis, it was possible to conclude that the massive consumption of stimulants is related to the processes of pathologization and medicalization of existence, set in motion by an articulation between the medical-scientific discourse and the capitalist discourse in contemporary times.(AU)

El consumo de drogas estimulantes ha crecido en los últimos años, en Brasil y en otros países. Diversas personas, especialmente niños y adolescentes, comenzaron a usar estimulantes como la terapia principal utilizada para tratar el trastorno por déficit de atención con hiperactividad (TDAH). En este contexto, los estimulantes como las anfetaminas y el metilfenidato, mejor conocidos por los nombres comerciales Adderall y Ritalina, han ganado visibilidad social debido a la asociación de estas drogas psicoactivas a la mejora de las funciones psíquicas, como la atención y el aumento de la calidad y el tiempo de rendimiento de los pacientes en diversas actividades. Como resultado, la demanda de estos estimulantes también ha aumentado por las personas que no reciben tratamiento médico, pero que buscan mejorar su desempeño en las actividades que realizan. Dado este escenario, el objetivo de este artículo era demostrar cómo el crecimiento en el consumo de estimulantes, ya sea por sujetos que reciben tratamiento médico o no, está relacionado con los procesos de socialización hegemónica en la sociedad capitalista actual. De la articulación del contexto presentado con los conceptos del psicoanálisis lacaniano se concluye que el consumo masivo de estimulantes está relacionado con los procesos de patologización y medicalización de la existencia, puestos en marcha por una articulación entre el discurso médico-científico y el discurso capitalista en los tiempos contemporáneos.(AU)

O universalismo da cura em Freud / The universalism of cure in Freud

Resumo: O objetivo é demonstrar que a reflexão sobre a cura é central para o surgimento da psicanálise entre a tradição clínica e a psicoterápica. Além de uma clínica ou uma psicoterapia, a psicanálise deve ser reconhecida como uma experiência de cura. Por fim, defenderemos que, por ter a cura como a realização de uma experiência singular em seu seio, a psicanálise freudiana estabelece uma proposta de cura de caráter universal: em cada realização singular da cura não teremos a integração da singularidade a nenhuma totalidade. A cura como a realização de uma experiência singular não será idêntica a nada.

Abstract: The objective is to demonstrate that the discussion about cure is central to the emergence of psychoanalysis between the clinical and psychotherapeutic tradition. In addition to a clinic or psychotherapy, psychoanalysis must be recognized as a cure experience. Finally, we will propose that, by affirming the cure as the realization of a singular experience, Freudian psychoanalysis establishes a proposal of universal healing: in each singular realization of healing we will not have the integration of the singularity into any totality. Cure as the realization of a singular experience will not be identical to anything.

Analysis of uncoated LPGs written in B-Ge doped fiber under proton irradiation for sensing applications at CERN.

In this contribution, a complete dissertation concerning the behavior of a Long Period Grating (LPG) inscribed in a B-Ge co-doped optical fiber by means of an excimer laser and exposed to proton irradiation during a recent extensive campaign performed at the European Organization for Nuclear Research (CERN) with a fluence of 4.4·1015 p∙cm-2 is provided. The experimental results have been thus combined for the first time to the best of our knowledge with numerical simulations in order to estimate the variations of the major parameters affecting the grating response during the ultra-high dose proton exposure. From the correlation between experimental and numerical analysis, the irradiation exposure was found to induce a maximal variation of the core effective refractive index of ~1.61·10-4, responsible of a resonance wavelength red shift of ~44 nm in correspondence of the highest absorbed radiation dose of 1.16 MGy. At the same time, a relevant decrease close to ~0.93·10-4 in the refractive index modulation pertaining to the grating was estimated, leading to a reduction of the resonant dip visibility of ~12 dB. The effect of the proton beam on the spectral response of the LPG device and on the optical fiber parameters was assessed during the relaxation phases, showing a partial recovery only of the wavelength shift without any relevant change in the dip visibility revealing thus a partial recovery only in the refractive index of the core while the reduction of the refractive index modulation observed during the irradiation remained unchanged.

Discordant patterns of introgression across a narrow hybrid zone between two cryptic lineages of an Iberian endemic newt.

The study of natural hybrid zones can illuminate aspects of lineage divergence and speciation in morphologically cryptic taxa. We studied a hybrid zone between two highly divergent but morphologically similar lineages (south-western and south-eastern) of the Iberian endemic Bosca's newt (Lissotriton boscai) in SW Iberia with a multilocus dataset (microsatellites, nuclear and mitochondrial genes). STRUCTURE and NEWHYBRIDS analyses retrieved few admixed individuals, which classified as backcrosses involving parental individuals of the south-western lineage. Our results show asymmetric introgression of mtDNA beyond the contact from this lineage into the south-eastern lineage. Analysis of nongeographic introgression patterns revealed asymmetries in the direction of introgression, but except for mtDNA, we did not find evidence for nonconcordant introgression patterns across nuclear loci. Analysis of a 150-km transect across the hybrid zone showed broadly coincident cline widths (ca. 3.2-27.9 km), and concordant cline centres across all markers, except for mtDNA that is displaced ca. 60 km northward. Results from ecological niche modelling show that the hybrid zone is in a climatically homogenous area with suitable habitat for the species, suggesting that contact between the two lineages is unlikely to occur further south as their distributions are currently separated by an extensive area of unfavourable habitat. Taken together, our findings suggest the genetic structure of this hybrid zone results from the interplay of historical (biogeographic) and population-level processes. The narrowness and coincidence of genetic clines can be explained by weak selection against hybrids and reflect a degree of reproductive isolation that is consistent with cryptic speciation.

A potência política do real / The political potency of the real / La potencia política de lo real

Nas últimas quatro décadas, a racionalidade neoliberal avançou sobre o cenário social, determinando o quadro de possibilidades da política através da generalização da concorrência como princípio universal das condutas e da empresa como modo privilegiado de subjetivação. Além de determinar os fins da política institucional, a racionalidade neoliberal também promoveu novas formas de sujeição social através da determinação dos modos de individuação e sociabilidade que devem ser assumidos pelos sujeitos para que tenham suas condutas reconhecidas. O saldo desse avanço é a ausência de transformações efetivas na política, uma vez que toda e qualquer transformação fora do quadro delimitado pelo neoliberalismo é considerada uma realização impossível. Diante desse contexto, o presente ensaio teórico objetivou promover uma articulação entre psicanálise e política por meio da extração da potência política do conceito de real presente na obra de Jacques Lacan. A negatividade do conceito lacaniano mostrou-se fecunda ao nos permitir defender que a política não pode ser pensada a partir de um regime de gestão das possibilidades de uma dada situação, pois a política é por excelência um acontecimento real, ou seja, trata-se justamente da realização através de processos disruptivos do que até então era considerado impossível pelo regime dominante.

In the last four decades, neoliberal rationality has advanced on the social scene, determining the framework of possibilities of politics through the generalization of competition as a universal principle of conduct and enterprise as a privileged mode of subjectivation. In addition to determining the ends of institutional politics, neoliberal rationality has also promoted new forms of social subjection through the determination of the modes of individuation and sociability that must be assumed by the subjects to have their behaviors recognized. The balance of this advance is the absence of effective transformations in politics, since any transformation outside the framework delimited by neoliberalism is considered an impossible realization. In view of this context, the present theoretical essay aimed at promoting an articulation between psychoanalysis and politics through the extraction of political power from the concept of real present in the work of Jacques Lacan. The negativity of the Lacanian concept has proved fruitful in allowing us to argue that politics cannot be thought from a regime of management of the possibilities of a given situation, since politics is par excellence a real event, that is, it is precisely from the realization through disruptive processes of what until then was considered impossible by the dominant regime.

En las últimas cuatro décadas, la racionalidad neoliberal avanzó sobre el escenario social, determinando el cuadro de posibilidades de la política a través de la generalización de la competencia como principio universal de las conductas y de la empresa como modo privilegiado de subjetivación. Además de determinar los fines de la política institucional, la racionalidad neoliberal también promovió nuevas formas de sujeción social a través de la determinación de los modos de individuación y sociabilidad que deben ser asumidos por los sujetos para que tengan sus conductas reconocidas. El saldo de ese avance es la ausencia de transformaciones efectivas en la política, ya que toda transformación fuera del marco delimitado por el neoliberalismo se considera una realización imposible. Ante este contexto, el presente ensayo teórico objetivó promover una articulación entre psicoanálisis y política por medio de la extracción de la potencia política del concepto de real presente en la obra de Jacques Lacan. La negatividad del concepto lacaniano se mostró fecunda al permitirnos defender que la política no puede ser pensada a partir de un régimen de gestión de las posibilidades de una determinada situación, pues la política es por excelencia un acontecimiento real, o sea, se trata justamente de la realización a través de procesos disruptivos de lo que hasta entonces era considerado imposible por el régimen dominante.

A dynamic continental moisture gradient drove Amazonian bird diversification.

The Amazon is the primary source of Neotropical diversity and a nexus for discussions on processes that drive biotic diversification. Biogeographers have focused on the roles of rivers and Pleistocene climate change in explaining high rates of speciation. We combine phylogeographic and niche-based paleodistributional projections for 23 upland terra firme forest bird lineages from across the Amazon to derive a new model of regional biological diversification. We found that climate-driven refugial dynamics interact with dynamic riverine barriers to produce a dominant pattern: Older lineages in the wetter western and northern parts of the Amazon gave rise to lineages in the drier southern and eastern parts. This climate/drainage basin evolution interaction links landscape dynamics with biotic diversification and explains the east-west diversity gradients across the Amazon.

Co-existing monophasic teratoma and uterine adenocarcinoma in a female dog.

Ovarian teratomas are occasionally reported in dogs; the rarest type is the monophasic teratoma, composed of tissues originating from only one germ layer. Canine endometrial adenocarcinomas are also rare in dogs and mainly affect geriatric females. This report describes the case of co-existing ovarian teratoma and uterine adenocarcinoma in a 10-year-old nulliparous female Boxer presented with lethargy, anorexia and purulent vaginal discharge. Abdominal ultrasonography evidenced pyometra and a mass in the left ovary. This was composed of a uniform whitish tissue with multiple cystic structures. The histology revealed an atrophy of the ovarian parenchyma, compressed by a proliferation of well-differentiated nervous tissue staining positively to vimentin, S100 and neuronal specific enolase (NSE), and negatively to keratin and inhibin. The left uterine horn, whose diameter was markedly increased, showed foci of endometrial cellular atypia, evident nucleoli and mitoses, at light microscopy. To our best knowledge, this is the first report of a co-existing ovarian monophasic teratoma and endometrial adenocarcinoma, two rare reproductive neoplasia in dogs.

Towards the Development of a Low-Cost Device for the Detection of Explosives Vapors by Fluorescence Quenching of Conjugated Polymers in Solid Matrices.

Conjugated polymers (CPs) have proved to be promising chemosensory materials for detecting nitroaromatic explosives vapors, as they quickly convert a chemical interaction into an easily-measured high-sensitivity optical output. The nitroaromatic analytes are strongly electron-deficient, whereas the conjugated polymer sensing materials are electron-rich. As a result, the photoexcitation of the CP is followed by electron transfer to the nitroaromatic analyte, resulting in a quenching of the light-emission from the conjugated polymer. The best CP in our studies was found to be poly[(9,9-dioctylfluorenyl-2,7-diyl)-co-bithiophene] (F8T2). It is photostable, has a good absorption between 400 and 450 nm, and a strong and structured fluorescence around 550 nm. Our studies indicate up to 96% quenching of light-emission, accompanied by a marked decrease in the fluorescence lifetime, upon exposure of the films of F8T2 in ethyl cellulose to nitrobenzene (NB) and 1,3-dinitrobenzene (DNB) vapors at room temperature. The effects of the polymeric matrix, plasticizer, and temperature have been studied, and the morphology of films determined by scanning electron microscopy (SEM) and confocal fluorescence microscopy. We have used ink jet printing to produce sensor films containing both sensor element and a fluorescence reference. In addition, a high dynamic range, intensity-based fluorometer, using a laser diode and a filtered photodiode was developed for use with this system.

Numerical study of the influence of electrode arrangements in electrokinetic remediation technique.

The effectiveness of electrokinetic remediation for soils depends on several factors such as the arrangement and shape of electrodes. This paper presents a numerical study on external electrostatic field generated by seven different electrode configurations in any unbounded two-dimensional domain. The boundary condition at infinity for the voltage is approximated by the iterative algorithm that expands the domain till the limit of the specified tolerance (threshold value). The numerical results indicate that there is no unique configuration with larger effective area for all spacings between the oppositely charged electrodes. In addition, the configuration with the smallest inactive electric field strength spots for all spacings between the electrodes is not unique. Moreover, the voltage profile for all electrode configurations is nonlinear, and the external electric field strength varies widely near the electrodes. Only in the intermediate region between the electrodes the external electric field strength approaches a constant value.

Uterine Extramedullary Plasmacytoma as a Primary Manifestation of Multiple Myeloma / Plasmocitoma extramedular uterino comomanifestação primária de mieloma múltiplo

Abstract The association between plasmacytomas and multiple myeloma (MM) is well-described, and in about one third of the cases of plasmacytoma the additional study will lead to the diagnosis of MM. The finding of plasmacytomas in the genital tract is extremely rare, with sparse cases described in the literature, and these cases pose a challenge regarding the optimal guidance and treatment. This paper describes a case of uterine extramedullary plasmacytoma in a 79-year-old woman with complaints of postmenopausal abnormal uterine bleeding. The complementary study led to the diagnosis of uterine plasmacytoma and, subsequently, of MM. Despite the unfavorable outcome of this case, we consider pertinent to report it because it constitutes a differential diagnosis to be taken into account in the approach of pelvic masses.

Resumo A associação entre plasmocitomas e mieloma múltiplo (MM) encontra-se bem demonstrada, e em cerca de um terço dos casos de plasmocitoma o estudo adicional conduzirá ao diagnóstico de MM. O achado de plasmocitomas no trato genital é extremamente raro, havendo um número muito limitado de casos descritos na literatura, o que dificulta concluir sobre a melhor forma de orientação e tratamento destes casos. O presente trabalho descreve um caso de plasmocitoma extramedular uterino em mulher de 79 anos estudada por queixas de hemorragia uterina anômala pós-menopáusica. O estudo complementar levou ao diagnóstico de plasmocitoma uterino e, posteriormente, de MM. Apesar do desfecho desfavorável do caso, consideramos pertinente o seu relato por se tratar de um diagnóstico diferencial a levar em consideração na abordagem de massas pélvicas.

Saúde é colocar-se em risco: normatividade vital em Georges Canguilhem / Health is putting oneself at risk: vital normativity in Georges Canguilhem

Resumo Este artigo objetiva apresentar uma crítica ao modelo biomédico de saúde predominante nas ciências médicas, a partir do conceito de normatividade vital, proposto por Georges Canguilhem. Na introdução apresentamos, a partir de um breve histórico do conceito de saúde, a normalização como o primado fundamental do modelo biomédico. Na primeira parte, discutimos o problema da determinação do normal e do patológico, da saúde e da doença, no pensamento de Canguilhem, buscando situar esses conceitos em função de valores individuais, questionando a existência de um processo normativo em biologia. Na segunda parte, pretende-se demonstrar que a normatividade vital defendida por Canguilhem é uma ferramenta conceitual fundamental para o entendimento da lógica de produção biológica. Esta lógica de produção não toma a norma como critério de valoração das formas de vida possíveis. Não são as individualidades biológicas que se adéquam ou se afastam das normas, mas, ao contrário, é a individualidade biológica enquanto potência de criação de novas formas que produz o processo de sua normatividade. Por fim, destacamos o impacto crítico do conceito de saúde entendido como uma abertura ao risco, enfatizando essa dimensão da saúde como a capacidade de enfrentar novas situações de vida.

Abstract This article aims to criticize the biomedical health model prevalent in medical sciences, based on the concept of vital normativity proposed by Georges Canguilhem. In the introduction we present, from a brief history of the health concept, normalization as the fundamental primacy of the biomedical model. In the first part, we discuss the problem of determining normal and pathological, health and illness in Canguilhem's thought, seeking to situate these concepts in function of individual values, questioning the existence of a normative process in Biology. In the second part, it aims to demonstrate that the vital normativity advocated by Canguilhem is a fundamental conceptual tool for the understanding of organic production logic. This production logic in Biology does not take the norm as criterion for valuing possible forms of life. Biological individuals do not fit or deviate from the rules, but biological individuality, as a power of generating new ways, produces the normativity process. Finally, we highlight the critical impact of the concept of health understood as an openness to risk, emphasizing this dimension of health as capacity to face new situations of life.

Uterine Extramedullary Plasmacytoma as a Primary Manifestation of Multiple Myeloma.

The association between plasmacytomas and multiple myeloma (MM) is well-described, and in about one third of the cases of plasmacytoma the additional study will lead to the diagnosis of MM. The finding of plasmacytomas in the genital tract is extremely rare, with sparse cases described in the literature, and these cases pose a challenge regarding the optimal guidance and treatment. This paper describes a case of uterine extramedullary plasmacytoma in a 79-year-old woman with complaints of postmenopausal abnormal uterine bleeding. The complementary study led to the diagnosis of uterine plasmacytoma and, subsequently, of MM. Despite the unfavorable outcome of this case, we consider pertinent to report it because it constitutes a differential diagnosis to be taken into account in the approach of pelvic masses.

A associação entre plasmocitomas e mieloma múltiplo (MM) encontra-se bem demonstrada, e em cerca de um terço dos casos de plasmocitoma o estudo adicional conduzirá ao diagnóstico de MM. O achado de plasmocitomas no trato genital é extremamente raro, havendo um número muito limitado de casos descritos na literatura, o que dificulta concluir sobre a melhor forma de orientação e tratamento destes casos. O presente trabalho descreve um caso de plasmocitoma extramedular uterino em mulher de 79 anos estudada por queixas de hemorragia uterina anômala pós-menopáusica. O estudo complementar levou ao diagnóstico de plasmocitoma uterino e, posteriormente, de MM. Apesar do desfecho desfavorável do caso, consideramos pertinente o seu relato por se tratar de um diagnóstico diferencial a levar em consideração na abordagem de massas pélvicas.