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1.
BMC Health Serv Res ; 24(1): 86, 2024 Jan 17.
Artigo em Inglês | MEDLINE | ID: mdl-38233921

RESUMO

BACKGROUND: Dementia is a global public health priority. The World Health Organization adopted a Global Action Plan on Dementia, with dementia awareness a priority. This study examined the knowledge, attitudes, and self-confidence with skills required for providing dementia care among primary health care providers in Vietnam. METHODS: A cross-sectional study was conducted with 405 primary health care providers who worked at commune health stations and district health centers in eight provinces across Vietnam. RESULTS: The results showed that primary health care providers had poor knowledge and little confidence but more positive attitudes toward dementia care and management. CONCLUSIONS: The results suggest the training needs for building capacity amongst primary health care providers, which will be critical as Vietnam's population ages.


Assuntos
Demência , Médicos , Humanos , Conhecimentos, Atitudes e Prática em Saúde , Vietnã , Estudos Transversais , Atenção Primária à Saúde , Demência/terapia
2.
Nat Prod Res ; 37(3): 455-461, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34542362

RESUMO

From the Lasianthus bidoupensis stems, two new compounds, including one new 9,10-anthraquinone, lasibidoupin A (1), and one new 6,7-benzocoumarin, lasibidoupin B (2), together with one known compound, 11-O-methyldamnacanthol (3) were isolated using chromatographic method. Their structures were determined by extensive HRMS, and NMR assignments. Compound 3 was reported for the first time from this species. New compounds (1 & 2) were tested for the cytotoxicity against three human cancer cell lines (MCF-7, HeLa, and NCI-H460) by SRB assay. As results, 1 & 2 exhibited significant cytotoxic activity against all cancer cell lines (IC50 ranged from 0.058 ± 0.003 to 0.177 ± 0.014 µM).


Assuntos
Antineoplásicos , Rubiaceae , Humanos , Linhagem Celular Tumoral , Células HeLa , Antineoplásicos/química , Rubiaceae/química , Espectroscopia de Ressonância Magnética
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