Biomedical Application of Identified Biomarkers Gene Expression Based Early Diagnosis and Detection in Cervical Cancer with Modified Probabilistic Neural Network.

Cervical squamous cell carcinoma (CSC) is expected to rise to become the fourth most prevalent cancer in women globally and to replace breast cancer as the top cause of death in women in the future years, according to the World Health Organization. According to the World Health Organization, developing countries are responsible for 86 percent of all cervical cancer cases globally in women aged 15 to 44 (WHO). Cancer mortality is associated with the largest amount of monotonous antecedent in low- and middle-income nations, while cancer mortality is associated with the least amount of monotonous antecedent in high-income countries. Cervical cancer is thought to be caused by aberrant proliferation of cells in the cervix that is capable of stealing or invading other human organs, according to current thinking. Cancer of the cerebral cell is the most prevalent kind of cancer in women. It is expected that cervical squamous cell carcinoma (CSC) will be the fourth most frequent cancer in the world and the main cause of death in women by the year 2050. Despite the fact that technology has improved tremendously since then, this is still the case. When compared to high-income countries, low- and middle-income countries have the highest consistent antecedent for cancer mortality, according to the World Cancer Research Fund. Cancerous growths of cells in the cervix, such as cervical cancer, are caused by cells that have the ability to steal from or invade auxiliary organs of the body, as is the case with cervical cancer. Although technological advances have been made in recent years, gene expression profiling continues to be a prominent approach in the investigation of cervical cancer. Since then, researchers have had the opportunity to examine a gene coexpression network, which has evolved into an exceptionally comprehensive technique for microarray research. This has helped them to get a better understanding of the human genome. When a specific biological issue is addressed, gene coexpression networks retain a considerable percentage of their once vast component of physiognomy, which was previously immense. When comparing the properties of genes in a population, it is well known that feature selection may be used to choose genes that outperform the rest of the genes in the population. There are several benefits to feature selection, and this is only one of them. Typically used gene selection approaches have been shown to be insufficient in acquiring the best potential sequence of genes for training purposes, and as a result, the accuracy of the classifier has likely suffered as a result of this. Recently, a considerable number of scientists have advocated for the use of optimization approaches in the process of gene selection, and this trend is expected to continue. A metaheuristic algorithm may be used to choose a suitable subset of genes, according to the preceding assertion, which is also consistent with the metaheuristic approach. A Modified Probabilistic Neural Network differs from other networks in that the underlying gene expression associated with DEGs and standard data in a Modified Probabilistic Neural Network is not uniformly distributed as it is in other networks (MPN). As previously said, selecting the most relevant genes or repeating genes is a vital step in the prediction process. It was this technique that was used in the research of cervical cancer. Since then, researchers have had the opportunity to examine a gene coexpression network, which has evolved into an exceptionally comprehensive technique for microarray research. This has helped them to get a better understanding of the human genome. When a specific biological issue is addressed, gene coexpression networks are able to preserve a previously major section of the face that had been lost. When comparing the properties of genes in a population, it is well known that feature selection may be used to choose genes that outperform the rest of the genes in the population. There are several benefits to feature selection, and this is only one of them. Typically used gene selection approaches have been shown to be insufficient in acquiring the best potential sequence of genes for training purposes, and as a result, the accuracy of the classifier has likely suffered as a result of this. In the field of gene selection, several scholars have argued in favor of the employment of optimization approaches. A metaheuristic algorithm may be used to choose a suitable subset of genes, according to the preceding assertion, which is also consistent with the metaheuristic approach. It was discovered that Modified Probabilistic Neural Networks (MPNs) had a different distribution of gene expression linked with DEGs and normal data than other networks, which had not been previously seen. This was previously unknown. Following what has been said before, selecting the most appropriate or repeated genes is a critical task throughout the prediction process.

Particle Swarm Optimization and Modular Multilevel Converter Communication in Electrical Applications with Machine Learning Algorithm.

As a result of their natural capacity to recover harmonic current and reactive power from alternating current sources, power electronic devices utilized in conjunction with nonlinear loads have the potential to generate significant harmonic problems within the power system when employed in this way. When this occurs, voltage instability occurs, which must be avoided in order to maintain the consistency and dependability of the power system's power flow. With this approach, the series controller has been replaced by a multilevel modular controller in order to improve power handling capability and achieve higher modular levels with minimal distortions. The shunt compensator is the most effective way to achieve an extremely protected energy system as well as righteous steadiness in electric potential difference under a variety of load constraints. The DQ thesis is employed in this proposed converter to separate the harmonic components by establishing reference frame current, which is accomplished by machine learning techniques. As part of the constant mode operation, the PI controller contributes to maintaining the direct current-potential difference, which is given to the PWM generator. Optimization of the values of K p and K i is accomplished by the use of particle swarm optimization (PSO). The construction of this power system simulation model has been made feasible by the use of time-fluctuating characteristics modeling and the MATLAB programming environment. The new (unified power flow controller) UPFC research that has been made available is persuasive in its capacity to reduce distortions and watt-less power components while simultaneously enhancing efficiency and reducing costs.

Machine Learning Technique to Detect and Classify Mental Illness on Social Media Using Lexicon-Based Recommender System.

The emergence of social media has allowed people to express their feelings on products, services, films, and so on. The feeling is the user's view or attitude towards any topic, object, event, or service. Overall, feelings have always influenced people's decision-making. In recent years, emotions have been analyzed intensively in natural language, but many problems still have to be watched. One of the most important problems is the lack of precise classification resources. Most of the research into feeling gradation is concerned with the issue of polarity grading, although, in many practical applications, this relatively grounded feeling measure is insufficient. Design methods are therefore essential, which can accurately classify feelings into a natural language. The principal goal of the research is to develop an overflow of grammatical rules-based classification of Indian language tweets. In this work, three main challenges are identified to classify feelings in Indian language tweets and possible methods for tackling such issues. Firstly, it has been found that the informal nature of tweets is crucial for the classification of feelings. Based on the tweets, the mental illness of the person has been classified. Therefore, to categorize Indian language tweets, a combination of grammar rules based on adjectives and negations is proposed. Secondly, people often express their feelings with slang words, abbreviations, and mixed words. A technique called field tags is used to include nongrammatical arguments such as slang words and diverse words. Thirdly, if a tweet is more complex, the morphological richness of the Indian language results in a loss of performance. The grammar rules are embedded in N-gram techniques and machine learning methods. These methods are grouped into three approaches, which functionally predict Indian language tweets with syntactic words.

Optimal Medical Image Size Reduction Model Creation Using Recurrent Neural Network and GenPSOWVQ.

Medical diagnosis is always a time and a sensitive approach to proper medical treatment. Automation systems have been developed to improve these issues. In the process of automation, images are processed and sent to the remote brain for processing and decision making. It is noted that the image is written for compaction to reduce processing and computational costs. Images require large storage and transmission resources to perform their operations. A good strategy for pictures compression can help minimize these requirements. The question of compressing data on accuracy is always a challenge. Therefore, to optimize imaging, it is necessary to reduce inconsistencies in medical imaging. So this document introduces a new image compression scheme called the GenPSOWVQ method that uses a recurrent neural network with wavelet VQ. The codebook is built using a combination of fragments and genetic algorithms. The newly developed image compression model attains precise compression while maintaining image accuracy with lower computational costs when encoding clinical images. The proposed method was tested using real-time medical imaging using PSNR, MSE, SSIM, NMSE, SNR, and CR indicators. Experimental results show that the proposed GenPSOWVQ method yields higher PSNR SSIMM values for a given compression ratio than the existing methods. In addition, the proposed GenPSOWVQ method yields lower values of MSE, RMSE, and SNR for a given compression ratio than the existing methods.

IntOPMICM: Intelligent Medical Image Size Reduction Model.

Due to the increasing number of medical imaging images being utilized for the diagnosis and treatment of diseases, lossy or improper image compression has become more prevalent in recent years. The compression ratio and image quality, which are commonly quantified by PSNR values, are used to evaluate the performance of the lossy compression algorithm. This article introduces the IntOPMICM technique, a new image compression scheme that combines GenPSO and VQ. A combination of fragments and genetic algorithms was used to create the codebook. PSNR, MSE, SSIM, NMSE, SNR, and CR indicators were used to test the suggested technique using real-time medical imaging. The suggested IntOPMICM approach produces higher PSNR SSIM values for a given compression ratio than existing methods, according to experimental data. Furthermore, for a given compression ratio, the suggested IntOPMICM approach produces lower MSE, RMSE, and SNR values than existing methods.

A Liver Damage Prediction Using Partial Differential Segmentation with Improved Convolutional Neural Network.

Background: The liver is one of the most significant and most essential organs in the human body. It is divided into two granular lobes, one on the right and one on the left, connected by a bile duct. The liver is essential in the removal of waste products from human food consumption, the creation of bile, the regulation of metabolic activities, the cleaning of the blood by sensitizing digestive management, and the storage of vitamins and minerals. To perform the classification of liver illnesses using computed tomography (CT scans), two critical phases must first be completed: liver segmentation and categorization. The most difficult challenge in categorizing liver disease is distinguishing the liver from the other organs near it. Methodology. Liver biopsy is a kind of invasive diagnostic procedure, widely regarded as the gold standard for accurately estimating the severity of liver disease. Noninvasive approaches for examining liver illnesses, such as blood serum markers and medical imaging (ultrasound, magnetic resonance MR, and CT) have also been developed. This approach uses the Partial Differential Technique (PDT) to separate the liver from the other organs and Level Set Methodology (LSM) for separating the cancer location from the surrounding tissue based on the projected pictures used as input. With the help of an Improved Convolutional Classifier, the categorization of different phases may be accomplished. Results: Several accuracies, sensitivity, and specificity measurements are produced to assess the categorization of LSM using an Improved Convolutional classifier. Approximately, 97.5% of the performance accuracy of the liver categorization is achieved with a 94.5% continuous interval (CI) of [0.6775 1.0000] and an error rate of 2.1%. The suggested method's performance is compared to that of two existing algorithms, and the sensitivity and specificity provide an overall average of 96% and 93%, respectively, with 95% Continuous Interval of [0.7513 1.0000] and [0.7126 1.0000] for sensitivity and specificity, respectively.

Data Mining in Employee Healthcare Detection Using Intelligence Techniques for Industry Development.

BACKGROUND: Even in today's environment, when there is a plethora of information accessible, it may be difficult to make appropriate choices for one's well-being. Data mining, machine learning, and computational statistics are among the most popular arenas of training today, and they are all aimed at secondary empowered person in making good decisions that will maximize the outcome of whatever working area they are involved with. Because the degree of rise in the number of patient roles is directly related to the rate of people growth and lifestyle variations, the healthcare sector has a significant need for data processing services. When it comes to cancer, the prognosis is an expression that relates to the possibility of the patient surviving in general, but it may also be used to describe the severity of the sickness as it will present itself in the patient's future timeline. Methodology. The proposed technique consists of three stages: input data acquisition, preprocessing, and classification. Data acquisition consists of input raw data which is followed by preprocessing to eliminate the missed data and the classification is carried out using ensemble classifier to analyze the stages of cancer. This study explored the combined influence of the prominent labels in conjunction with one another utilizing the multilabel classifier approach, which is successful. Finally, an ensemble classifier model has been constructed and experimentally validated to increase the accuracy of the classifier model, which has been previously shown. The entire performance of the recommended and tested models demonstrates a steady development of 2% to 6% over the baseline presentation on the baseline performance. RESULTS: Providing a good contribution to the general health welfare of noncommercial potential workers in the healthcare sector is an opportunity provided by this recommended job outcome. It is anticipated that alternative solutions to these constraints, as well as automation of the whole process flow of all five phases, will be the key focus of the work to be carried out shortly. Predicting health status of employee in industry or information trends is made easier by these data patterns. The proposed classifier achieves the accuracy rate of 93.265%.

Machine Learning Techniques for Human Age and Gender Identification Based on Teeth X-Ray Images.

The use of digital medical images is increasing with advanced computational power that has immensely contributed to developing more sophisticated machine learning techniques. Determination of age and gender of individuals was manually performed by forensic experts by their professional skills, which may take a few days to generate results. A fully automated system was developed that identifies the gender of humans and age based on digital images of teeth. Since teeth are a strong and unique part of the human body that exhibits least subject to risk in natural structure and remains unchanged for a longer duration, the process of identification of gender- and age-related information from human beings is systematically carried out by analyzing OPG (orthopantomogram) images. A total of 1142 digital X-ray images of teeth were obtained from dental colleges from the population of the middle-east part of Karnataka state in India. 80% of the digital images were considered for training purposes, and the remaining 20% of teeth images were for the testing cases. The proposed gender and age determination system finds its application widely in the forensic field to predict results quickly and accurately. The prediction system was carried out using Multiclass SVM (MSVM) classifier algorithm for age estimation and LIBSVM classifier for gender prediction, and 96% of accuracy was achieved from the system.

Enabling Artificial Intelligence of Things (AIoT) Healthcare Architectures and Listing Security Issues.

A significant study has been undertaken in the areas of health care and administration of cutting-edge artificial intelligence (AI) technologies throughout the previous decade. Healthcare professionals studied smart gadgets and other medical technologies, along with the AI-based Internet of Things (IoT) (AIoT). Connecting the two regions makes sense in terms of improving care for rural and isolated resident individuals. The healthcare industry has made tremendous strides in efficiency, affordability, and usefulness as a result of new research options and major cost reductions. This includes instructions (AIoT-based) medical advancements can be both beneficial and detrimental. While the IoT concept undoubtedly offers a number of benefits, it also poses fundamental security and privacy concerns regarding medical data. However, resource-constrained AIoT devices are vulnerable to a number of assaults, which can significantly impair their performance. Cryptographic algorithms used in the past are inadequate for safeguarding IoT-enabled networks, presenting substantial security risks. The AIoT is made up of three layers: perception, network, and application, all of which are vulnerable to security threats. These threats can be aggressive or passive in nature, and they can originate both within and outside the network. Numerous IoT security issues, including replay, sniffing, and eavesdropping, have the ability to obstruct network communication. The AIoT-H application is likely to be explored in this research article due to its potential to aid with existing and different technologies, as well as bring useful solutions to healthcare security challenges. Additionally, every day, several potential problems and inconsistencies with the AIoT-H technique have been discovered.

Optimized Tree Strategy with Principal Component Analysis Using Feature Selection-Based Classification for Newborn Infant's Jaundice Symptoms.

One of the most important and difficult research fields is newborn jaundice grading. The mitotic count is an important component in determining the severity of newborn jaundice. The use of principal component analysis (PCA) feature selection and an optimal tree strategy classifier to produce automatic mitotic detection in histopathology images and grading is given. This study makes use of real-time and benchmark datasets, as well as specific approaches for detecting jaundice in newborn newborns. According to research, the quality of the feature may have a negative impact on categorization performance. Additionally, compressing the classification method for exclusive main properties can result in a classification performance bottleneck. As a result, identifying appropriate characteristics for training the classifier is required. By combining a feature selection method with a classification model, this is possible. The major outcomes of this study revealed that image processing techniques are critical for predicting neonatal hyperbilirubinemia. Image processing is a method of translating analogue images to digital formats and manipulating them. The primary goal of medical image processing is to collect information useful for disease detection, diagnosis, monitoring, and therapy. Image datasets can be used to validate the performance of newborn jaundice detection. When compared to conventional approaches, it offers results that are accurate, quick, and time efficient. Accuracy, sensitivity, and specificity, which are common performance indicators, were also predictive.