RESUMO
The purpose of this study was to determine whether six weeks of high intensity interval training (HIIT) would lead to greater changes in resting concentrations of salivary IL-8 and IL-1ra than moderate intensity continuous training (MICT) in young, healthy adults, and to determine whether changes in IL-8 and IL-1ra after six weeks of either HIIT or MICT were associated with changes in maximal exercise capacity (VO2max). Participants were randomly assigned to 6 weeks of HIIT (n = 12) or MICT (n = 11), matched for workload. Saliva samples were collected at the beginning (T1) and end (T2) of the intervention, and analyzed for IL-8 and IL-1ra. Participants in both groups had significant improvements in VO2max; there were no group differences in improvements. A greater reduction in IL-8 was observed in the MICT group when compared to the HIIT group (HIIT median: -9.5; MICT median: -82.3 pg/µg of protein; U = 11.5, p < 0.001). When combining the HIIT and MICT group, there were significant reductions in IL-8 from T1 to T2. There was no correlation between changes in IL-8 (r < 0.00) or IL-1ra (r = -0.013) with changes in VO2max. In conclusion, 6 weeks of exercise training leads to a reduction in IL-8; MICT may lead to greater reductions when compared to HIIT. Future research examining longer intervention periods is needed to further elucidate the effects of HIIT and MICT on different pro and anti-inflammatory cytokines.
Assuntos
Treinamento Intervalado de Alta Intensidade , Adulto , Exercício Físico , Humanos , Proteína Antagonista do Receptor de Interleucina 1 , Interleucina-8 , Consumo de OxigênioRESUMO
The coronavirus disease (COVID-19) pandemic disproportionately affects those with pre-existing conditions and has exacerbated gender inequalities. Cardiovascular disease (CVD) is the leading cause of death among Canadian women. Exercise improves physical and mental health and CVD management. Amid the pandemic, women are experiencing an increase in caregiving responsibilities, job insecurities, and domestic violence creating competing demands for prioritizing their health. Recommendations on how to meet the unique needs of Canadian women with CVD through exercise are provided. Novelty: Exercise recommendations amid the pandemic for women with CVD need to be flexible, feasible, and fun.
Assuntos
COVID-19 , Doenças Cardiovasculares/terapia , Exercício Físico , Disparidades nos Níveis de Saúde , Saúde Mental , Saúde da Mulher , Canadá , Doenças Cardiovasculares/epidemiologia , Feminino , Humanos , Guias de Prática Clínica como Assunto , Fatores de RiscoRESUMO
The aim of this study was to compare the central and peripheral components of cardiorespiratory fitness during incremental to maximal exercise between older men who were either recreational athletes (RA) or leisurely active (LA) men, i.e., those who fall between trained and untrained. This was a cross-sectional study in which all subjects completed an exercise test on a cycle ergometer. Maximal oxygen consumption (VO(2max)) and ventilatory threshold (VT) were assessed using gas analysis, and central components of VO(2max) were assessed using a non-invasive thoracic bio-impedance device. VO(2max) (RA: 45.1+/-4.8 ml/kg/min; LA: 32.2+/-4.6 ml/kg/min, p=0.001) and SV at maximal exercise (RA: 133.5+/-24.96 ml/beat; LA: 107.9+/-17.6 ml/beat, p=0.005) were higher in the RA group compared to the LA group. A plateau in SV occurred between 30-45 % of maximal exercise capacity in the RA group. No differences in SV were observed across workloads in the LA group. No differences in the calculated arterio-venous oxygen difference ((a-v)O(2diff)) were observed between groups. In conclusions, training volume appears to influence central components of cardiorespiratory fitness among a matched sample of older men who are neither trained nor untrained. This builds a case for increasing the volume of training to preserve cardiorespiratory fitness among older men.