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Sci Rep ; 7(1): 9697, 2017 08 29.
Artigo em Inglês | MEDLINE | ID: mdl-28852173

RESUMO

The rice blast fungus Magnaporthe oryzae differentiates a specialized infection structure called an appressorium to invade rice cells. In this report, we show that CBP1, which encodes a chitin-deacetylase, is involved in the induction phase of appressorium differentiation. We demonstrate that the enzymatic activity of Cbp1 is critical for appressorium formation. M. oryzae has six CDA homologues in addition to Cbp1, but none of these are indispensable for appressorium formation. We observed chitosan localization at the fungal cell wall using OGA488. This observation suggests that Cbp1-catalysed conversion of chitin into chitosan occurs at the cell wall of germ tubes during appressorium differentiation by M. oryzae. Taken together, our results provide evidence that the chitin deacetylase activity of Cbp1 is necessary for appressorium formation.


Assuntos
Amidoidrolases/metabolismo , Magnaporthe/enzimologia , Oryza/microbiologia , Doenças das Plantas/microbiologia , Amidoidrolases/química , Amidoidrolases/genética , Sequência de Aminoácidos , Quitina/metabolismo , Ativação Enzimática , Teste de Complementação Genética , Interações Hospedeiro-Patógeno , Magnaporthe/metabolismo , Mutação
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