Knowledge Levels and Predictors of Venous Thromboembolism among Pregnant Women in Nigeria: A Cross-Sectional Survey for the 'Move for Flow' Programme.

BACKGROUND: Pregnancy is a significant risk factor for Venous Thromboembolism (VTE) which results in high maternal and perinatal morbidity and mortality rates. Awareness creation is one of the preventable strategies of VTE. To this effect, we designed the 'Move for Flow' program aimed at maternal health education on VTE, its symptoms and preventive strategies. For the best implementation of this program, the current knowledge level of the relevant population is of great interest in guiding the program design and implementation. AIM: To assess the knowledge levels of VTE among Nigerian pregnant women. METHODOLOGY: In this cross-sectional survey, 1000 pregnant women residing in Enugu, Nigeria, completed a structured questionnaire which assessed their knowledge of VTE, its risk factors and prevention strategies. Quantitatively, their knowledge levels were categorized as no, poor, average and good knowledge. RESULTS: The majority of the respondents did not know about pregnancy-related deep vein thrombosis (DVT) (80.8%) and pulmonary embolism (PE) (88.9). Predictors of DVT knowledge levels include husbands' level of education (at most secondary education) (AOR = 4.2; 95%CI = 2.554-6.816; p = <0.001) and maternal age (AOR = 0.9; 95% CI = 0.930-0.999; p = 0.044) while predictors of PE knowledge level include husbands' level of education (at most secondary education) (AOR = 2.1; 95%CI = 1.005-4.436; p = 0.048) and maternal occupation (professionals) (AOR = 0.4; 95% CI = 0.219- 0.794; p = 0.008). CONCLUSION: Pregnant women are unaware of pregnancy-related VTE in Enugu, Nigeria. Immediate designing and implementation of the 'Move for Flow' program are recommended to improve maternal knowledge levels of VTE.

CONTEXTE: La grossesse est un facteur de risque important pour la thromboembolie veineuse (TEV), qui entraîne des taux élevés de morbidité et de mortalité maternelles et périnatales. La sensibilisation est l'une des stratégies de prévention de la TEV. À cet effet, nous avons conçu le programme "Move for Flow", qui vise à éduquer les mères sur la TEV, ses symptômes et les stratégies de prévention.Pour une mise en œuvre optimale de ce programme, le niveau de connaissance actuel de la population concernée est d'un grand intérêt pour guider la conception et la mise en œuvre du programme. OBJECTIF: Évaluer le niveau de connaissance de la TEV chez les femmes enceintes nigérianes. MÉTHODOLOGIE: Dans cette enquête transversale, 1000 femmesenceintes résidant à Enugu, au Nigeria, ont rempli un questionnaire structuré qui évaluait leurs connaissances sur la TEV, ses facteurs de risque et les stratégies de prévention. D'un point de vue quantitatif, leurs connaissances ont été classées en trois catégories : pas de connaissance, faible connaissance, connaissance moyenne et bonne connaissance. RÉSULTATS: La majorité des personnes interrogées ne connaissaient pas la thrombose veineuse profonde (TVP) (80,8 %) et l'embolie pulmonaire (EP) liées à la grossesse (88,9 %). Les facteurs prédictifs des niveaux de connaissance de la TVP comprennent le niveau d'éducation du mari (au plus l'éducation secondaire) (AOR=4,2 ; 95% CI =2,554-6,816 ; p= <0,001) et l'âge de la mère (AOR=0,9 ; 95% CI=0,930-0,999 ; p=0. 044) tandis que les prédicteurs du niveau de connaissance de l'EP incluent le niveau d'éducation du mari (auplus l'éducation secondaire) (AOR=2.1 ; 95%CI=1.005-4.436 ; p=0.048) et la profession de la mère (professionnels) (AOR=0.4 ; 95% CI=0.219-0.794 ; p=0.008). CONCLUSION: Les femmes enceintes ne sont pas conscientes de la TEV liée à la grossesse à Enugu, au Nigeria. La conception et la mise en œuvre immédiates du programme " Move for Flow " sont recommandées pour améliorer les connaissances maternelles sur la. Mots clés: Grossesse, Thromboembolie veineuse, Thrombose veineuse profonde, Embolie pulmonaire, Nigeria.

Insecticide susceptibility of Anopheles coluzzii and Anopheles gambiae mosquitoes in Ibadan, Southwest Nigeria.

The emergence of insecticide resistance in Anopheles (Diptera: Culicidae) mosquitoes has great implications for malaria control in Nigeria. This study aimed to determine the dynamics of insecticide susceptibility levels and the frequency of knock-down resistance (kdr) mutations (L1014F) in wild Anopheles coluzzii Coetzee & Wilkerson sp. n. and Anopheles gambiae Giles from the Ojoo and Bodija areas of Ibadan, in southwest Nigeria. Insecticide susceptibility to pyrethroids, organophosphates, carbamates and organochlorines was assessed using World Health Organization (WHO) bioassays. A subset of the mosquitoes exposed to pyrethroids and DDT was used for species and molecular form identification; kdr genotyping was determined using the TaqMan real-time polymerase chain reaction assay. The mosquitoes were resistant to pyrethroids and DDT but completely susceptible to organophosphates and carbamates. Bodija samples (n = 186) consisted of An. gambiae (91.4%) and An. coluzzii (8.1%) and included one An. coluzzii/An. gambiae hybrid specimen. All mosquitoes screened in Ojoo (n = 26) were An. gambiae. The 1014F kdr mutation was detected at frequencies of 24.5 and 5.8% in Bodija and Ojoo, respectively. No correlation was observed between kdr genotypes and resistance phenotypes. The results indicate that metabolic resistance probably plays an important role in the development of resistance and highlight the need to implement insecticide resistance management strategies.

Application of geographical information system for lymphatic filariasis and malaria control in Nigeria.

Geographical Information System (GIS) is defined as an information system used to capture, store, edit, retrieve, analyze and visualize geographically referenced data. The use of GIS is one technology that is very useful in the prevention and control of Vector Borne Diseases (VBDs) such as lymphatic filariasis (LF) and malaria which cause high morbidity and mortality in Nigeria. This paper focuses on how the use of Geographical Information System (GIS) can be harnessed for surveillance, prevention and control of LF and malaria in Nigeria. GIS can be used as an operational tool to assist with resource allocation, as a monitoring and evaluation tool and as a tool to investigate various research projects on spatial aspects of LF and malaria epidemiology. This paper provides information on the benefits and potential of using GIS as a tool for the national malaria and LF control programmes with particular reference to Nigeria.