Asymptomatic lymphogranuloma venereum is commonly found among men who have sex with men in Austria.

BACKGROUND AND OBJECTIVES: Serovar L1-L3 of Chlamydia trachomatis (CT) causes lymphogranuloma venereum (LGV). A surge in LGV-cases has been observed among HIV-positive men who have sex with men (MSM). Discrimination between LGV and non-LGV is pivotal since it has major treatment implications. Here, we aimed to determine the prevalence and characteristics of LGV among CT-infections. PATIENTS AND METHODS: All CT-positive results from 04/2014-12/2021 at the four largest Austrian HIV and STI clinics were evaluated. Disease characteristics and patient demographics were analyzed. RESULTS: Overall, n  =  2,083 infections of CT were documented in n  =  1,479 individual patients: median age was 31.4 years, 81% were male, 59% MSM, 44% HIV-positive, 13% on HIV pre-exposure-prophylaxis. Available serovar analyses (61% [1,258/2,083]) showed L1-L3 in 15% (192/1,258). Considering only MSM with rectal CT-infection, LGV accounted for 23% (101/439). Cases of LGV vs. other CT-infections were primarily MSM (92% [177/192] vs. 62% [1,179/1,891], p < 0.001), more often HIV-positive (64% [116/180] vs. 46% [631/1,376]; p < 0.001) and had frequently concomitant syphilis infection (18% [32/180] vs. 7% [52/749]; p < 0.001). LGV commonly manifested as proctitis (38% [72/192]) whereas 45% (87/192) were asymptomatic. CONCLUSIONS: Lymphogranuloma venereum accounted for 23% of rectal CT-infections in MSM. Furthermore, 45% of all LGV-cases were asymptomatic. In the absence of CT-serovar analysis, a high LGV prevalence should be considered in risk-populations and guide empiric treatment selection.

Granulometric and pebble morphometric applications to Benin Flank sediments in western Anambra Basin, Nigeria: proxies for paleoenvironmental reconstruction.

Integrated granulometric and pebble morphometric study of Late Cretaceous rocks of the Benin Flank, Nigeria, were used to delineate depositional process and environment of the rocks in the study area. Granulometric analysis reveals that the sandstones of the Lokoja Bassange Formation have an average graphic mean (Mz) of 0.59Φ (coarse grains), inclusive graphic standard deviation (δi) of 1.36Φ (poorly sorted), graphic kurtosis (Ka) of 1.12Φ (leptokurtic), and inclusive graphic skewness (Ski) of - 0.14Φ (stongly coarse skewed). The sandstones for the Mamu Formation have an average Mz of 1.42Φ (medium grains), inclusive graphic standard deviation (δi) of 0.74Φ (moderately sorted), graphic kurtosis (Ka) of 1.43Φ (leptokurtic), and inclusive graphic skewness (Ski) of 0.02Φ (nearly symetrical). The sandstones for the Ajali Formation have an average Mz of 1.23Φ (medium grains), inclusive graphic standard deviation (δi) of 1.21Φ (poorly sorted), graphic kurtosis (Ka) of 1.46Φ (leptokurtic), and inclusive graphic skewness (Ski) of - 0.17Φ (nearly symetrical). Pebble morphometric analysis of the larger grains reveals that the mean values of elongation ratio (ER) = 0.69, coefficient of flatness (FI) = 54.90%, oblate-prolate index (OPI) = 3.34, the maximum projection sphericity index (MPSI) = 0.75, form = 0.67, and roundness (ρ) = 36.28% for the Lokoja Bassange Formation; ER = 0.76, FI = 37.07%, OPI = -3.20, the MPSI = 0.53, form = 0.38, and ρ = 52.93% for the Mamu Formation; and ER = 0.72, FI = 47.44%, OPI = 1.12, the MPSI = 0.67, form = 0.54 and ρ = 42.68% for the Ajali Formation. The integration of the various granulometric and pebble morphometric data, different bivariate and ternary plots indicate fluvial environment for the Lokoja Bassange Formation, dominantly shallow marine environment for the Mamu Formation and fluvial - shallow marine environment for the Ajali Formation. This study shows that the Benin Flank, western Anambra Basin has a depositional setting radiating between fluvial and shallow marine environments.

Providing information about the consequences of female genital mutilation to healthcare providers caring for women and girls living with female genital mutilation: A systematic review.

BACKGROUND: The persistence of female genital mutilation (FGM) in some countries, despite an overall decline in the prevalence of the practice, calls for improvement in the capacity of healthcare workers and institutions to provide optimal care for this population. OBJECTIVES: To determine the impact of providing information on FGM and its consequences to healthcare providers on their attitudes toward FGM, and quality of care and patient satisfaction. SEARCH STRATEGY: The following major databases were searched from inception to August 2015: Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, SCOPUS, Web of Science, and ClinicalTrials.gov, without language restrictions. SELECTION CRITERIA: Controlled studies were included based on use of objective measures. DATA COLLECTION AND ANALYSIS: Two team members independently screened and collected data. Relative risks and proportions were calculated and evidence assessed using the GRADE (Grade of Recommendation, Assessment, Development and Evaluation) approach. RESULTS: One study was identified. Based on this study there was no evidence to suggest change in healthcare provider outcomes after the intervention. CONCLUSIONS: Despite a comprehensive search, only one study of low methodological quality was included. This precludes a definitive conclusion regarding the impact of providing information on FGM to healthcare providers. More research is needed. PROSPERO REGISTRATION: CRD42015024570.