Assuntos
Diafragma/patologia , Neoplasias Cardíacas/diagnóstico , Rabdomiossarcoma/diagnóstico , Idoso , Diagnóstico Diferencial , Diagnóstico por Imagem , Eletrocardiografia , Evolução Fatal , Neoplasias Cardíacas/patologia , Humanos , Masculino , Invasividade Neoplásica , Rabdomiossarcoma/patologiaAssuntos
Mycobacterium bovis/isolamento & purificação , Peritonite Tuberculosa/microbiologia , Tuberculose Pleural/microbiologia , Antituberculosos/farmacologia , Antituberculosos/uso terapêutico , Terapia Combinada , Resistência Microbiana a Medicamentos , Quimioterapia Combinada , Feminino , Humanos , Pessoa de Meia-Idade , Mycobacterium bovis/efeitos dos fármacos , Peritonite Tuberculosa/tratamento farmacológico , Derrame Pleural/tratamento farmacológico , Derrame Pleural/etiologia , Derrame Pleural/microbiologia , Derrame Pleural/cirurgia , Pirazinamida/farmacologia , Pirazinamida/uso terapêutico , Toracentese , Tuberculose Pleural/tratamento farmacológico , Tuberculose Pleural/cirurgiaRESUMO
BACKGROUND AND OBJECTIVE: White coat effect (WCE) is one of the main bias that can affect office blood pressure (BP) measurement. Therefore, it is a factor must be considered in hypertensives to avoid mistakes in diagnosis and/or treatment. Employment of automated office BP (AOBP) devices could diminish that effect. METHODS: Two studies were designed with the objective of evaluating differences between routinely office and AOBP measurements. WCE was also assessed. First, the TRUE-ESP study included normotensive and hypertensive patients attending specialized consultations at Cardiology, Nephrology, Internal Medicine, Endocrinology and Family Practice. Second, the TRUE-HTA study included hypertensives attending a protocoled Hypertension Unit, with a trained staff. RESULTS: TRUE-ESP study included 300 patients, 76% being hypertensives. A significant difference between office BP and AOBP measurement (SBP/DBP 9.8±11.6/3.4±7.9 mmHg, P<.001) was observed. Percentage of patients gathering WCE criteria was 27.7%. TRUE-HTA study included 101 hypertensive patients. A significant difference between office BP and AOBP measurement (SBP/DBP 5.7±9.3/2.1±5.3 mmHg, P<.001) and activity period-ABPM (SBP/DBP 8.5±6.7/3.5±2.5 mmHg, P<.001) was observed. Percentage of WCE patients was 32.1%. CONCLUSIONS: Use of AOBP devices can contribute to decrease WCE and to improve accuracy of office BP measurement.