1.
Nanoscale
; 13(1): 66-70, 2021 Jan 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33350424
RESUMO
Here, we introduce an artificial bioluminescent nanocompartment based on the encapsulation of light-producing enzymes, luciferases, inside polymersomes. We exploit nanocompartmentalization to enhance luciferase stability in a cellular environment but also to positively modulate enzyme kinetics to achieve a long-lasting glow type signal. These features pave the way for expanding bioluminescence to nanotechnology-based applications.