Association between stress hyperglycemia ratio with short-term and long-term mortality in critically ill patients with ischemic stroke.

AIMS: Hyperglycemia on admission is associated with poor prognosis in ischemic stroke (IS) patients. We aimed to investigate the relationship between stress hyperglycemia ratio (SHR) and short-term or long-term mortality in IS patients in the ICU and to explore whether this relationship is influenced by diabetes status. MATERIALS AND METHODS: We collected patients with severe IS requiring ICU admission in the Medical Information Mart for Intensive Care (MIMIC-IV) database and calculated SHR. Outcomes included 30-day, 90-day, and 1-year mortality. The association between SHR and mortality in patients with critical IS was elucidated using Multivariate Cox regression and subgroup analysis for diabetes. RESULTS: A total of 1376 patients were recruited. After adjusting for potential confounders, patients in the third and fourth quartiles had a significantly increased risk of death at 30 days, 90 days, and 1 year compared to the first quartile of SHR (Q3 vs. Q1: HR 1.56-1.80, all p < 0.02; Q4 vs. Q1: HR 1.75-2.15, all p < 0.001; all p for trend < 0.001). In addition, the highest quartile of SHR was significantly associated with short-term or long-term mortality compared with the first quartile, regardless of diabetes status. CONCLUSIONS: Our results suggest that stress hyperglycemia, defined by the glucose/HbA1c ratio, is associated with increased short-term and long-term mortality in patients with ischemic stroke, independent of the patient's diabetes status.

Building Interior Layout Design Based on Building Information Model and Deep Learning Technology: Taking the Interior Renewal Design of the Fifth Floor of the Procuratorate of Dong Xi Hu District as an Example.

With the development of the Internet era and the information age, electronic information technology has profoundly affected human life and work, and the architectural design industry is no exception. Architectural design has a complex design period, and the arbitrary division of labour reflects the particularity of its working process. At present, the integration of electronic information technology and scientific and technological software into architectural design has dramatically improved the work efficiency of designers. However, due to the enormous workload of drawing and modification of building drawings, and many professional departments involved in cooperation, the error rate of drawing design is still high, which eventually leads to a series of serious problems such as stagnation of the design process and rework of construction. However, due to the enormous workload of drawing and modification of building drawings, and many professional departments involved in cooperation, the error rate of drawing design is still high, which eventually leads to a series of serious problems such as stagnation of the design process and rework of construction. The BIM building information model system is an electronic information platform for comprehensive architectural design majors. It can integrate the design drawings of various majors in the design process, correct the design problems caused by inaccurate pictures at the first time, and reduce the errors in the design process. Through the BIM system and Python programming software, cross-platform cooperation is carried out to carry out computer deep learning and a series of extra design work. This paper puts forward the interior design method of the BIM system and shows the research work of interior design by the BIM building information platform through practical cases. By comparing with traditional design methods, the advantages of this technology in interior design are demonstrated, and a reference for future interior design informatization is provided.

Camphorsulfonic Acid-Mediated One-Pot Tandem Consecutive via the Ugi Four-Component Reaction for the Synthesis of Functionalized Indole and 2-Quinolone Derivatives by Switching Solvents.

A camphorsulfonic acid-mediated one-pot tandem consecutive approach was developed to synthesize functionalized indole and 2-quinolone derivatives from the Ugi four-component reaction by switching solvents. A reaction of the Ugi adduct in an aprotic solvent undergoes 5-exo-trig cyclization to form an indole ring. In a protic solvent, however, the Ugi adduct undergoes an alkyne-carbonyl metathesis reaction to form a 2-quinolone ring.