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Exp Clin Transplant ; 19(7): 732-735, 2021 07.
Artigo em Inglês | MEDLINE | ID: mdl-31580237

RESUMO

With the rising incidence of end-stage renal disease in the United States, patients needing renal transplants are waiting longer for increasingly scarce grafts. Formerly, the general practice was to avoid organs with tumors for transplant because of the risk of malignancy transmission to the recipient. However, with comprehensive donor selection and a small-sized primary tumor, the positive outcomes of transplant outweigh the risks of transmission after a partial nephrectomy. In our case, a 31-year-old woman, the daughter of the recipient, underwent a laparoscopic nephrectomy with an existing 8-mm tumor later confirmed as renal cell carcinoma. An ex vivo tumor enucleation was performed before the allograft was transplanted into the 69-year-old patient with endstage renal disease. At last follow-up, graft function has remained excellent with no evidence of local recurrence or metastasis in both the donor and recipient. Here, we describe our case and perform a literature review on the incidence and management of renal allografts with incidentally detected renal cell carcinoma during transplant.


Assuntos
Carcinoma de Células Renais , Falência Renal Crônica , Neoplasias Renais , Transplante de Rim , Adulto , Idoso , Aloenxertos/patologia , Carcinoma de Células Renais/patologia , Carcinoma de Células Renais/cirurgia , Feminino , Humanos , Falência Renal Crônica/complicações , Falência Renal Crônica/diagnóstico , Falência Renal Crônica/cirurgia , Neoplasias Renais/patologia , Transplante de Rim/efeitos adversos , Masculino , Nefrectomia/efeitos adversos , Resultado do Tratamento , Estados Unidos
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