Risk Factors for Death Among 120,804 Hospitalized Patients with Confirmed COVID-19 in São Paulo, Brazil.

São Paulo is a state in Brazil with one of the highest numbers of confirmed and severe cases of coronavirus disease (COVID-19), with an incidence of 294 hospitalizations per 100,000 inhabitants. We report the clinical characteristics and outcomes of 120,804 hospitalized patients with confirmed COVID-19 from February 26 to October 10, 2020, in São Paulo. Characteristics of patients who died and survived were compared using a survival analysis. The median age was 60 years (interquartile range [IQR], 47-72), 67,821 (56.1%) were men, and 61,659 (51.0%) were white. Most hospitalized patients (79,812; 66.1%) reported one or more comorbidities, 41,708 (34.5%) hospitalized patients were admitted to intensive care units, and 33,079 (27.4%) died. Men (hazard ratio [HR], 1.22; 95% confidence interval [CI], 1.18-1.25), elderly individuals (HR, 3.85; 95% CI, 3.68-4.02), and patients with chronic cardiovascular disease including hypertension (HR, 1.05; 95% CI, 1.02-1.08), chronic lung disease (HR, 1.38; 95% CI, 1.31-1.45), diabetes mellitus (HR, 1.14; 95% CI, 1.11-1.18), and chronic neurological disease (HR, 1.48; 95% CI, 1.41-1.55) were at higher risk for death from COVID-19.

The role of pregnant women with rash in the Zika virus sentinel surveillance.

INTRODUCTION: The state of São Paulo has been monitoring cases of microcephaly and pregnant women presenting with acute rash, through CeVeSP. METHODS: This was a descriptive study focusing on pregnant women with rash and the outcome of their pregnancy, based on the notifications through the CeVeSP. RESULTS: During 2016, 2,209 cases of pregnant women with rash were reported and investigated. Of these, 36.6% were confirmed. Of the pregnant women who tested positive for ZIKV, 6.4% did not have a favorable outcome. CONCLUSIONS: Our results allowed the characterization of pregnant women exposed to ZIKV and the outcome of pregnancy.

The role of pregnant women with rash in the Zika virus sentinel surveillance

Abstract INTRODUCTION: The state of São Paulo has been monitoring cases of microcephaly and pregnant women presenting with acute rash, through CeVeSP. METHODS: This was a descriptive study focusing on pregnant women with rash and the outcome of their pregnancy, based on the notifications through the CeVeSP. RESULTS: During 2016, 2,209 cases of pregnant women with rash were reported and investigated. Of these, 36.6% were confirmed. Of the pregnant women who tested positive for ZIKV, 6.4% did not have a favorable outcome. CONCLUSIONS Our results allowed the characterization of pregnant women exposed to ZIKV and the outcome of pregnancy.

The role of pregnant women with rash in the Zika virus sentinel surveillance

INTRODUCTION: The state of São Paulo has been monitoring cases of microcephaly and pregnant women presenting with acute rash, through CeVeSP. METHODS: This was a descriptive study focusing on pregnant women with rash and the outcome of their pregnancy, based on the notifications through the CeVeSP. RESULTS: During 2016, 2,209 cases of pregnant women with rash were reported and investigated. Of these, 36.6% were confirmed. Of the pregnant women who tested positive for ZIKV, 6.4% did not have a favorable outcome. CONCLUSIONS Our results allowed the characterization of pregnant women exposed to ZIKV and the outcome of pregnancy.

Detecção de infecção pelo vírus da hepatite B nos municípios brasileiros segundo cobertura dos serviços de hemoterapia, no período de 2001 a 2008 / Detection of infection by hepatitis B virus in the brazilian municipalities according to the coverage of hemotherapy services, in the period from 2001 to 2008

OBJETIVO: descrever a taxa de detecção de infecção pelo vírus da hepatite B no Brasil e a razão de taxas de detecção nos municípios segundo cobertura dos serviços de hemoterapia (SH) durante o período 2001-2008. MÉTODOS: estudo descritivo, compreendeu o cálculo da taxa de detecção de infecção pelo vírus da hepatite B por sexo, faixa etária, Regiões brasileiras e presença de SH; regressão linear para tendência; teste de qui-quadrado para comparação de proporções da detecção e razão de taxas; os dados foram coletados do Sistema de Informação de Agravos de Notificação (Sinan-NET). RESULTADOS: a taxa de detecção de infecção pelo vírus da hepatite B apresentou incremento no Brasil, sendo 2,4 vezes mais elevada nos municípios com SH. CONCLUSÃO: a detecção da infecção pelo vírus da hepatite B apresentou pequeno incremento no período estudado e em todas as Regiões brasileiras foram encontradas taxas mais elevadas em municípios com serviço de hemoterapia.

OBJECTIVE: to describe the detection rate of infection by hepatitis B virus in Brazil and detection rates ratio in municipalities regarding hemotherapy service (HS) during the period 2001-2008. METHODS: a descriptive study reached the detection rate of infection by hepatitis Bvirus by gender, age, Brazilian macro-regions and presence of HS; it was applied linear regression for trend, and chi-squared test to compare proportions of detection and ratio rates; data from the Reportable Diseases Database (Sinan-NET) was used. RESULTS: the detection rates of infection by hepatitis B virus showed increase in Brazil, and were 2.4 higherin municipalities with HS. CONCLUSION: the detection of infection by hepatitis B virus showed small increase during the study period, and all Brazilian regions presented higher rates in municipalities with hemotherapy service.