Speech, Facial and Fine Motor Features for Conversation-Based Remote Assessment and Monitoring of Parkinson's Disease.

We present a cloud-based multimodal dialogue platform for the remote assessment and monitoring of speech, facial and fine motor function in Parkinson's Disease (PD) at scale, along with a preliminary investigation of the efficacy of the various metrics automatically extracted by the platform. 22 healthy controls and 38 people with Parkinson's Disease (pPD) were instructed to complete four interactive sessions, spaced a week apart, on the platform. Each session involved a battery of tasks designed to elicit speech, facial movements and finger movements. We find that speech, facial kinematic and finger movement dexterity metrics show statistically significant differences between controls and pPD. We further investigate the sensitivity, specificity, reliability and generalisability of these metrics. Our results offer encouraging evidence for the utility of automatically-extracted audiovisual analytics in remote mon-itoring of PD and other movement disorders.

Using modified incremental chart parsing to ascribe intentions to animated geometric figures.

People spontaneously ascribe intentions on the basis of observed behavior, and research shows that they do this even with simple geometric figures moving in a plane. The latter fact suggests that 2-D animations isolate critical information--object movement--that people use to infer the possible intentions (if any) underlying observed behavior. This article describes an approach to using motion information to model the ascription of intentions to simple figures. Incremental chart parsing is a technique developed in natural-language processing that builds up an understanding as text comes in one word at a time. We modified this technique to develop a system that uses spatiotemporal constraints about simple figures and their observed movements in order to propose candidate intentions or nonagentive causes. Candidates are identified via partial parses using a library of rules, and confidence scores are assigned so that candidates can be ranked. As observations come in, the system revises its candidates and updates the confidence scores. We describe a pilot study demonstrating that people generally perceive a simple animation in a manner consistent with the model.