Soil pollution fingerprints of children playgrounds in Sarajevo city, Bosnia and Herzegovina.

This is the first study, 10 years after the war activities, to report about the content of heavy metals and metalloids, polycyclic aromatic hydrocarbons (PAHs), and polychlorinated biphenyls (PCBs) found in samples of soils from selected playgrounds in Sarajevo. Due to the fact that children are in direct contact with surface soils, it has been recommended that children's playgrounds should be given special consideration in this respect. Basic properties (pH in H2O, pH in 1 mol dm-3 KCl, humus, and CaCO3) of the examined soils were determined. Samples for the determination of heavy metals and metalloids were prepared by microwave-assisted acid digestion and determined by using an inductively coupled plasma optical emission spectrometer. Fluorine was determined potentiometrically. Gas chromatography with mass spectrometry was used for determination of PAHs and PCBs. Determined contents (mg kg-1) for Cd, Pb, Hg, Cr, Ni, Cu, Zn, Co, Mo, Fe, Se, As, B, and F were in the ranges from: 0.031 ± 0.03 to 0.52 ± 0.05; 26.1 ± 2.5 to 47.7 ± 4.5; 0.07 ± 0.01 to 0.50 ± 0.08; 26.2 to 50; 19.5 ± 1.6 to 33.3 ± 2.7; 12.8 ± 1.8 to 31.9 ± 4.5; 56.0 ± 4.0 to 89.0 ± 6.5; 6.7 ± 0.6 to10.6 ± 1.0; <0.8; 3.05 to 7.35; 1.98 to 2.60; 6.5 ± 0.8 to 17.2 ± 2.0; 0.4 to 3.6, and 286 to 575, respectively. The total PAHs ranged between 0.184 ± 0.32 mg kg-1 and 7.983 ± 1.389 mg kg-1. The total PCBs was <0.002 mg kg-1. Our preliminary results may contribute to more accurate health risk assessments of the soils, and may be included in projects planning children's health risk assessments and adopting environmental legislation which has not been sufficiently regulated in Bosnia and Herzegovina so far.

Herbicide and pesticide occurrence in the soils of children's playgrounds in Sarajevo, Bosnia and Herzegovina.

Pesticide pollution in Sarajevo public playgrounds is an important health and environmental issue, and the lack of information about it is causing concerns amongst the general population as well as researchers. Since children are in direct contact with surface soils on children's playgrounds, such soils should be much more carefully examined. Furthermore, herbicides and pesticides get transmitted from soil surfaces brought from outside the urban areas, or they get dispersed following their direct applications in urban areas. Infants' and children's health can be directly affected by polluted soils because of the inherent toxicity and widespread use of the different pesticides in urban environments such as playgrounds. In addition to that, the presence of chromated copper arsenate (CCA) wood preservative pesticide found as soil pollutant in playing equipment was also documented. Soil samples from playgrounds were collected and analyzed for triazines, carbamates, dithiocarbamates, phenolic herbicides and organochlorine pesticides. Samples for the determination of heavy metals Cu, Cr and As were prepared by microwave-assisted acid digestion, and the findings were determined by using an inductively coupled plasma optical emission spectrometer. Triazines, carbamates, dithiocarbamates, chlorphenoxy compounds, phenolic herbicides, organochlorine pesticides and organotin compounds were detected in playground soils and their determined concentrations (mg/kg) were respectively found as follows: <0.005, <0.05, <0.5, < 0.4, <0.1, <0.001 and <0.004. The determined contents (mg/kg) of Cu, Cr and As were in the ranges from 16.77 to 80.21, from 7.14 to 15.45 and from 3.31 to 4.43, respectively. Our preliminary results raise concerns about potential adverse effects of herbicides and pesticides on human health, which strengthens the case for a more preventative and protective approach to the uncontrolled presence of herbicides and pesticides in Sarajevo's playground soils.

Plasma lipids, lipoproteins and hormones levels during olanzapine treatment in psychosis and depression.

Weight gain is common adverse effect associated with the use of most typical and atypical antipsychotic. Aim of this study was to investigate plasma lipids, lipoproteins and some hormones levels during olanzapine treatment in patients with psychosis. The study population comprised twenty nine patients (29) diagnosed with psychosis and eleven patients (11) with endogenous depression. Plasma cholesterol, triglicerides, phospholipids, high-density lipoprotein cholesterol (HDL-C), very-low-density lipoprotein cholesterol (VLDL-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein A-I (ApoA-I) and apolipoprotein B (Apo B), and hormones - prolactin, cortisol, follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone and estradiol were measured by auto-analyzer and by classic photometric methods. All measurements were performed before and during one-year treatment with olanzapine and antidepressant. Treatment of the schizophrenic patients with olanzapine caused a great metabolic impact that is primarily expressed in body mass, cholesterol increase and statistically significant rise of BMI, respectively. Body mass increase could be explained by the fact that olanzapine blocked not only dopaminergic, serotonergic, cholinergic, alpha-adrenergic but histaminergic receptors as well.