RESUMO
Listeriosis is a food borne illness of significant public health concern, caused by consumption of food contaminated by gram negative bacilli, Listeria monocytogenes. Clinical listeriosis is relatively rare and it has varying spectrum of presentation, ranging from severe sepsis in immune-compromised individuals, febrile gastroenteritis and meningo-encephalitis in infants and adults. This disease is under reported in developing nations due to the lack of awareness and inadequate laboratory facilities to promptly isolate and identify the organism. We report a case of sporadic food-borne listeriosis, in an otherwise healthy individual presenting with meningo-encephalitis. Prompt identification and appropriate antibiotic therapy led to a favorable outcome.
Assuntos
Doenças Transmitidas por Alimentos/microbiologia , Listeria monocytogenes/isolamento & purificação , Listeriose/diagnóstico , Listeriose/tratamento farmacológico , Meningoencefalite/diagnóstico , Ampicilina/uso terapêutico , Antibacterianos/uso terapêutico , Doenças Transmitidas por Alimentos/diagnóstico , Doenças Transmitidas por Alimentos/tratamento farmacológico , Gentamicinas/uso terapêutico , Hepatomegalia/microbiologia , Humanos , Índia , Listeriose/transmissão , Masculino , Meningoencefalite/tratamento farmacológico , Meningoencefalite/microbiologia , Pessoa de Meia-Idade , Esplenomegalia/microbiologiaRESUMO
Endarteritis is a major complication in patients with patent ductus arteriosus, causing significant morbidity and mortality. We report an adult patient with asymptomatic patent ductus arteriosus and endarteritis involving the main pulmonary artery and secondary infective spondylodiscitis at the L5-S1 intervertebral disc caused by Abiotrophia defectivaA. defectiva, commonly referred to as nutritionally variant streptococci, cannot be identified easily by conventional blood culture techniques from clinical specimens. Its isolation was confirmed by 16S ribosomal RNA sequencing. The patient was successfully managed with a combination of penicillin G and gentamicin, pending surgical repair of the patent ductus arteriosus.
Assuntos
Abiotrophia/isolamento & purificação , Discite/microbiologia , Endarterite/microbiologia , Infecções por Bactérias Gram-Positivas/diagnóstico , Abiotrophia/classificação , Abiotrophia/genética , Discite/tratamento farmacológico , Permeabilidade do Canal Arterial/complicações , Endarterite/tratamento farmacológico , Feminino , Infecções por Bactérias Gram-Positivas/tratamento farmacológico , Humanos , Vértebras Lombares/microbiologia , Pessoa de Meia-Idade , Penicilina G/uso terapêutico , Sacro/microbiologia , Análise de Sequência de RNARESUMO
Resistance to colistin is a major threat that limits therapeutic choices for treating carbapenem-resistant Klebsiella pneumoniae infections. Herein, we report the draft genome sequences of two colistin-resistant K. pneumoniae isolates (BA41763 and B6753). The sequence data indicate that BA41763 and B6753 contain genomes of ~5.9 and 5.7 Mb in size with several plasmids.