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Postepy Hig Med Dosw (Online) ; 64: 161-6, 2010 Mar 31.
Artigo em Polonês | MEDLINE | ID: mdl-20354264

RESUMO

Gemini surfactants are a new class of amphiphilic compounds built from two classic surfactant moieties bound together by a special spacer group. These compounds appear to be excellent for creating complexes with DNA and are effective in mediating transfection. Thanks to their construction, DNA carrier molecules built from gemini surfactants are able to deliver genes to cells of almost any DNA molecule size, unattainable when using viral gene delivery systems. Moreover, they are much safer for living organisms.


Assuntos
Técnicas de Transferência de Genes , Tensoativos/química , Transfecção , Humanos
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