[The procedure for the surgical treatment of spinal and spinal cord trauma in the acute period]. / Taktika khirurgicheskogo lecheniia pozvonochno-spinnomozgovoi travmy v ostrom periode.

Examination and treatment policy is proposed for patients with complicated vertebral injury under the conditions of urgent neurosurgical service. Its practical use at Saint Petersburg city multidisciplinary hospital No. 26 in 207 patients with vertebral and spinal cord injury substantially improved the outcomes of this severe group of patients. A wide range of surgical interventions into the vertebral column was used. Treatment yielded fair and good results in 188 (85.9%) patients.

[Intralymphatic administration of antibiotics in the complex treatment of suppurative complications in patients with neurosurgical pathology]. / Endolimfaticheskoe vvedenie antibiotikov v kompleksnom lechenii gnoinykn oslozhnenii u bol'nykh s neirokhirurgicheskoi patologiei.

The efficacy of endolymphatic route of gentamicin and ceporin administration was studied in 89 patients with neurosurgical pathological processes complicated by acute pneumonia (80 patients) and meningoencephalitis (9 patients) usually after ineffective antibiotic therapy according to the routine methods. The antibiotics were used in accordance with the antibiograms of the causative agents isolated from the bronchial tree or CSF. The endolymphatic use of gentamicin or ceporin once a day in doses of 80 mg or 1 g respectively provided rapid sanation and arresting of the inflammatory foci, lowering of the intoxication level, more rapid promotion of the positive time course of the clinico-roentgenological and laboratory indices and decreasing of the recovery periods by 1.5-2 times in 86 per cent of the patients with pneumonia. The endolymphatic administration of gentamicin in a dose of 80 mg twice a day or ceporin in a dose of 1 g twice a day allowed one to maintain the antibiotic therapeutic levels in the cerebrospinal fluid and to obtain satisfactory clinical results in the combined treatment of meningoencephalitis. The endolymphatic administration of the drugs was well tolerated by the patients and no adverse reactions were observed. This route of administration of antibiotics and in particular broad spectrum antibiotics may be recommended for urgent antibacterial therapy of especially severe neurosurgical patients with pyo-inflammatory complications and patients who did not respond to the routine antibiotic therapy.