Research priorities in veterinary palliative care.

Veterinary palliative care consists of end-of-life care of companion animals suffering from terminal or life-limiting diseases. Despite the growing need for veterinary palliative care, little research has been conducted on this topic. This perspective intends to provide an overview of the existing concerns and identify knowledge gaps to motivate further research. As a result, three main areas of research have been identified, namely: i) how to provide palliative care considering welfare implications of different diseases (e.g., pain management); ii) what can be considered a "good death", depending on the individual situation of the animal and its caregiver; iii) how to support caregivers' needs during their companion animal's end-of-life. Therefore, veterinary palliative care involves medical, ethical, and sociological considerations that should be addressed through guidelines and training.

Strategies for the Improvement of Pet Health and Welfare in Portugal Based on a Pilot Survey on Husbandry, Opinion, and Information Needs.

Pets are present in half of the homes across Portugal. However, little is known about the husbandry, opinion, and information needs of Portuguese pet owners. Thus, the objective of this work was to clarify this information providing the basis for suggesting potential improvements. Responses were collected through an online survey, including inhabitants from different regions of Portugal (n = 111). Cats and dogs are the most popular pets and the majority are adopted, fed commercial diets, live indoors, are vaccinated, dewormed, and treated for external parasites, and occasionally visit the veterinary practice. Portuguese owners are interested in improving their pet's health, and would like to learn more about welfare, health assessment, and diet from veterinarians. However, microchip and municipal registration are often overlooked. Lack of adoption from animal shelters as well as expectations over the cost of veterinary practice were other difficulties identified in this study. Strategies for the improvement of pet health and welfare in Portugal were proposed as improving the perception of the value and importance of veterinary care, reducing the number of lost and abandoned pets, and improving awareness and education. Thus, Portuguese stakeholders and authorities must take the required measures to improve these issues.

Environmental exposure to microplastics: An overview on possible human health effects.

Microplastics are ubiquitous environmental contaminants leading to inevitable human exposure. Even so, little is known about the effects of microplastics in human health. Thus, in this work we review the evidence for potential negative effects of microplastics in the human body, focusing on pathways of exposure and toxicity. Exposure may occur by ingestion, inhalation and dermal contact due to the presence of microplastics in products, foodstuff and air. In all biological systems, microplastic exposure may cause particle toxicity, with oxidative stress, inflammatory lesions and increased uptake or translocation. The inability of the immune system to remove synthetic particles may lead to chronic inflammation and increase risk of neoplasia. Furthermore, microplastics may release their constituents, adsorbed contaminants and pathogenic organisms. Nonetheless, knowledge on microplastic toxicity is still limited and largely influenced by exposure concentration, particle properties, adsorbed contaminants, tissues involved and individual susceptibility, requiring further research.

Effects of microplastics on microalgae populations: A critical review.

Microplastics are persistent contaminants accumulating in the environment. Aquatic ecosystems have been studied worldwide, revealing ubiquitous contamination with microplastics. Microalgae, one of the most important primary producers in aquatic ecosystems, could suffer from microplastic contamination, leading to larger impacts on aquatic food webs. Nonetheless, little is known about the toxic effects of microplastics on microalgae populations. Thus, the objective of this review was to identify these effects and the impacts of microplastics on microalgae populations based on currently available literature, also identifying knowledge gaps. Even though microplastics seem to have limited effects on parameters such as growth, chlorophyll content, photosynthesis activity and reactive oxygen species (ROS), current environmental concentrations are not expected to induce toxicity. Even so, microplastics could disrupt population regulation mechanisms, by reducing the availability or absorption of nutrients (bottom-up) or reducing the population of predator species (top-down). Microplastics' properties can also influence the effects on microalgae, with smaller sizes and positive surface charges having higher toxicity. Therefore, more research is needed to better understand the effects of microplastics on microalgae, such as adaptation strategies, effects on population dynamics and microplastics properties influencing toxicity.

Microplastics in wastewater: State of the knowledge on sources, fate and solutions.

Microplastics are ubiquitous contaminants that could harm ecosystems. Wastewater contains microplastics and may lead to further contamination of the environment. This focus article presents a summary of current knowledge on microplastics in wastewater and possible solutions, suggesting current research needs.

Airborne microplastics: Consequences to human health?

Microplastics have recently been detected in atmospheric fallout in Greater Paris. Due to their small size, they can be inhaled and may induce lesions in the respiratory system dependent on individual susceptibility and particle properties. Even though airborne microplastics are a new topic, several observational studies have reported the inhalation of plastic fibers and particles, especially in exposed workers, often coursing with dyspnea caused by airway and interstitial inflammatory responses. Even though environmental concentrations are low, susceptible individuals may be at risk of developing similar lesions. To better understand airborne microplastics risk to human health, this work summarizes current knowledge with the intention of developing awareness and future research in this area.