Non-Antibiotic Prevention of Catheter Mechanic and Septic Complications in Patients with Long-Term Indwelling Catheters: a Crossover Prospective Study Involving L-Methionine.

Bacterial antimicrobial resistance (AMR) is a major public health concern in modern society caused by bacterial changes that impair the efficacy of infection-treating drugs. Non-antibiotic techniques are critical for controlling the antimicrobial resistance concern because they provide a means of alleviating symptoms without needing antibiotics. This prospective study aims to determine whether administering L-methionine reduces mechanical and bacterial problems associated with long-term indwelling urinary catheters. The trial focused on administering only L-methionine for a three-month period to patients who had long-term bladder catheters, either indwelling or suprapubic. The catheter exchange rates were categorized according to acute urinary tract infection, macroscopic haematuria and symptomatic urinary tract infection. During the time of inclusion, catheter-related incidents were recorded. The primary incident observed was acute urine retention caused by catheter obstruction in 63.6.

Arteriovenous Fistula: The Case of a Rare Complication after Minimal Percutaneous Nephrostomy and Brief Review.

Percutaneous renal surgery, although much less invasive than other procedures, is subject to several complications, which can occur at any time during the course of treatment, starting from the performance of the minimal nephrostomy procedure. We present an extremely rare vascular complication of percutaneous nephrostomy represented by arteriovenous fistula that occurred in a 24-year-old patient known to have right ureteropelvic junction obstruction operated with the absence of double-J catheter permeability and grade II-III hydronephrosis for which minimal percutaneous nephrostomy was urgently fitted. The arteriovenous fistula was resolved by supraselective artery embolization.

The Role and Significance of Bioumoral Markers in Prostate Cancer.

The prostate is one of the most clinically accessible internal organs of the genitourinary tract in men. For decades, the only method of screening for prostate cancer (PCa) has been digital rectal examination of 1990s significantly increased the incidence and prevalence of PCa and consequently the morbidity and mortality associated with this disease. In addition, the different types of oncology treatment methods have been linked to specific complications and side effects, which would affect the patient's quality of life. In the first two decades of the 21st century, over-detection and over-treatment of PCa patients has generated enormous costs for health systems, especially in Europe and the United States. The Prostate Specific Antigen (PSA) is still the most common and accessible screening blood test for PCa, but with low sensibility and specificity at lower values (<10 ng/mL). Therefore, in order to avoid unnecessary biopsies, several screening tests (blood, urine, or genetic) have been developed. This review analyzes the most used bioumoral markers for PCa screening and also those that could predict the evolution of metastases of patients diagnosed with PCa.