RESUMO
The complex evaluation of the intensity of lipid peroxidation, endogenous intoxication syndrome, blood microcirculation disorder and surfactant activity of blood serum has been performed in patients with hepatitis of non-viral etiology. The article presents the peculiarities of changes of blood medium-molecular peptides, average corpuscular volume of erythrocytes, albumin/gamma-globulin coefficient in patients with chronic hepatitis of non-viral etiology with different activity degree. These indices were proposed to evaluate endogenous intoxication syndrome. On the basis of the analysis of changes of tension-rheometric indices the method of assessment of chronic hepatitis activity of non-viral etiology has been worked out.
Assuntos
Proteínas Sanguíneas/análise , Hepatite Alcoólica/sangue , Peroxidação de Lipídeos , Adulto , Idoso , Catalase/metabolismo , Eritrócitos/citologia , Eritrócitos/metabolismo , Testes Hematológicos , Hepatite Alcoólica/enzimologia , Hepatite Alcoólica/metabolismo , Humanos , Peróxidos Lipídicos/sangue , Pessoa de Meia-Idade , Superóxido Dismutase/metabolismo , SíndromeRESUMO
The study of 37 patients with chronic obstructive bronchitis combined with coronary heart disease during exacerbation of these diseases has revealed blood microcirculation disorders of its vascular, intra- and extravascular parts. It's also showed an increase in specific quantity of blood serum medium- and high-molecular surface-active substances, in mean corpuscular volume and sorptive activity of erythrocytes, nitrite/nitrate contents, and medium-molecular peptides. It has been revealed at the same time cytogenetic derangements of lymphocytes, low monocyte phagocytic activity. There were only 25.7% of the observed patients, who presented with some normal indices by the time of clinical remission of the diseases.
Assuntos
Bronquite Crônica/sangue , Hemorreologia , Isquemia Miocárdica/sangue , Adulto , Complexo Antígeno-Anticorpo/sangue , Viscosidade Sanguínea/fisiologia , Bronquite Crônica/complicações , Bronquite Crônica/fisiopatologia , Agregação Eritrocítica/fisiologia , Deformação Eritrocítica/fisiologia , Feminino , Humanos , Masculino , Microcirculação/fisiologia , Isquemia Miocárdica/complicações , Isquemia Miocárdica/fisiopatologia , Óxidos de Nitrogênio/sangue , Peptídeos/sangue , Surfactantes Pulmonares/sangueRESUMO
The paper represents results of use of dynamic interphase tensiometry of the blood serum in patients with chronic cryptogenic hepatitis. Studied in a comparative aspect in patients with varying degree of severity of the course of chronic cryptogenic hepatitis were features of indices for the blood serum dynamic surface tension and relations between them. The above technique is an important investigational tool to evaluate the course of chronic cryptogenic hepatitis.