Oxidized Xanthan Gum Crosslinked NOCC: Hydrogel System and Their Biological Stability from Oxidation Levels of the Polymer.

Dynamic hydrogel systems from N,O-carboxymethyl chitosan (NOCC) are investigated in the past years, which has facilitated their widespread use in many biomedical engineering applications. However, the influence of the polymer's oxidation levels on the hydrogel biological properties is not fully investigated. In this study, chitosan is converted into NOCC and introduced to react spontaneously with oxidized xanthan gum (OXG) to form several injectable hydrogels with controlled degradability. Different oxidation levels of xanthan gum, as well as NOCC/OXG volume ratios, are trialed. The infrared spectroscopy spectra verify chemical modification on OXG and successful crosslinking. With increasing oxidation levels, more dialdehyde groups are introduced into the OXG, resulting in changes in physical properties including gelation, swelling, and self-healing efficiency. Under different volume ratios, the hydrogel shows a stable structure and rigidity with higher mechanical properties, and a slower degradation rate. The shear-thinning and self-healing properties of the hydrogels are confirmed. In vitro assays with L929 cells show the biocompatibility of all formulations although the use of a high amount of OXG15 and OXG25 limited the cell proliferation capacity. Findings in this study suggested a suitable amount of OXG at different oxidation levels in NOCC hydrogel systems for tissue engineering applications.

The removal enhancement of organic contaminations and optimization of the photocatalytic efficiency by Box-Behnken design using ZnO-TiO2/porous graphene aerogel.

In this study, zinc oxide-titanium dioxide/graphene aerogel (ZnO-TiO2/GA) was successfully synthesized through a simple and cost-effective hydrothermal self-assembly process. Besides, the surface response model and the experimental design according to the Box-Behnken model were selected to determine the optimal removal efficiency for crystal violet (CV) dye and para-nitrophenol (p-NP) phenolic compound. According to the obtained results, the highest degradation efficiency for CV dye of 99.6% was obtained under the following conditions: pH 6.7, CV concentration of 23.0 mg/L, and catalyst dose of 0.30 g/L. For p-NP, the degradation efficiency reached 99.1% under the following conditions: H2O2 volume of 1.25 mL, pH 6.8, and catalyst dose of 0.35 g/L. Therewithal, kinetic models of adsorption-photodegradation, thermodynamic adsorption, and free radical scavenging experiments were also investigated to propose the specific mechanisms involving the removal of CV dye and p-NP. According to the aforementioned results, the study provided a resulting ternary nanocomposite with great removal performance for water pollutants via the synergetic effects of adsorption and photodegradation processes.