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1.
Cureus ; 16(5): e60148, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38864066

RESUMO

BACKGROUND AND OBJECTIVES: Childbirth is mainly thought to be a woman's concern, and mortality can be prevented by making a birth plan constituting birth preparedness and complication readiness with the entire family as one unit. Indian National Plans aim to increase male involvement, but the policies lack directions and monitoring systems; hence, it becomes important to address this issue. METHODOLOGY:  A cross-sectional study conducted in a rural hospital and a community-based setup included 350 male participants, consisting of new fathers or expecting fathers, who were interviewed with the help of a questionnaire. RESULTS: Only 28.29% of male participants were well involved in the process of birth preparedness and complication readiness. 83% of the husbands accompanied their respective wives during ANC visits (mean number of visits: 5.76). 33% of males were aware of various danger signs and complications related to pregnancy. The males with better education (p-value < 0.005) and economic status (p-value < 0.0001) had better birth preparedness. Several variables in the study were positively correlated with the amount of money saved.  Interpretation and conclusion: Male involvement during pregnancy significantly impacts maternal and child health outcomes. However, this study highlights a lack of awareness and involvement among males. We strongly recommend enhancing existing maternal and child health (MCH) programs to include components focused on male partner engagement in birth preparedness, complication readiness, and obstetric emergencies.

2.
Sci Rep ; 14(1): 7045, 2024 Mar 25.
Artigo em Inglês | MEDLINE | ID: mdl-38528081

RESUMO

Fins are widely used in many industrial applications, including heat exchangers. They benefit from a relatively economical design cost, are lightweight, and are quite miniature. Thus, this study investigates the influence of a wavy fin structure subjected to convective effects with internal heat generation. The thermal distribution, considered a steady condition in one dimension, is described by a unique implementation of a physics-informed neural network (PINN) as part of machine-learning intelligent strategies for analyzing heat transfer in a convective wavy fin. This novel research explores the use of PINNs to examine the effect of the nonlinearity of temperature equation and boundary conditions by altering the hyperparameters of the architecture. The non-linear ordinary differential equation (ODE) involved with heat transfer is reduced into a dimensionless form utilizing the non-dimensional variables to simplify the problem. Furthermore, Runge-Kutta Fehlberg's fourth-fifth order (RKF-45) approach is implemented to evaluate the simplified equations numerically. To predict the wavy fin's heat transfer properties, an advanced neural network model is created without using a traditional data-driven approach, the ability to solve ODEs explicitly by incorporating a mean squared error-based loss function. The obtained results divulge that an increase in the thermal conductivity variable upsurges the thermal distribution. In contrast, a decrease in temperature profile is caused due to the augmentation in the convective-conductive variable values.

3.
Rheumatology (Oxford) ; 63(3): 657-664, 2024 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-37228012

RESUMO

OBJECTIVES: We aimed to explore current practice and interregional differences in the treatment of idiopathic inflammatory myopathies (IIMs). We triangulated these observations considering countries' gross national income (GNI), disease subtypes, and symptoms using patient-reported information. METHODS: A cross-sectional ancillary analysis of the 'COVID-19 vaccination in auto-immune disease' (COVAD) e-survey containing demographic characteristics, IIM subtypes (DM, PM, IBM, anti-synthetase syndrome [ASSD], immune-mediated necrotizing myopathy [IMNM], overlap myopathies [OM]), current symptoms (surrogate for organ involvement) and treatments (corticosteroids [CS], immunomodulators [IM], i.e. antimalarials, immunosuppressants [IS], IVIG, biologic treatments and targeted-synthetic small molecules). Treatments were presented descriptively according to continents, GNI, IIM and organ involvement, and associated factors were analysed using multivariable binary logistic regressions. RESULTS: Of 18 851 respondents from 94 countries, 1418 with IIM were analysed (age 61 years, 62.5% females). DM (32.4%), IBM (24.5%) and OM (15.8%) were the most common subtypes. Treatment categories included IS (49.4%), CS (38.5%), IM (13.8%) and IVIG (9.4%). Notably, treatments varied across regions, GNI categories (IS mostly used in higher-middle income, IM in lower-middle income, IVIG and biologics largely limited to high-income countries), IIM subtypes (IS and CS associated with ASSD, IM with OM and DM, IVIG with IMNM, and biologic treatments with OM and ASSD) and disease manifestations (IS and CS with dyspnoea). Most inter-regional treatment disparities persisted after multivariable analysis. CONCLUSION: We identified marked regional treatment disparities in a global cohort of IIM. These observations highlight the need for international consensus-driven management guidelines considering patient-centred care and available resources.


Assuntos
Doenças Autoimunes , Miosite , Feminino , Humanos , Pessoa de Meia-Idade , Masculino , Vacinas contra COVID-19 , Estudos Transversais , Imunoglobulinas Intravenosas/uso terapêutico , Miosite/tratamento farmacológico , Imunossupressores/uso terapêutico , Adjuvantes Imunológicos
4.
Rheumatology (Oxford) ; 63(1): 127-139, 2024 Jan 04.
Artigo em Inglês | MEDLINE | ID: mdl-37084267

RESUMO

OBJECTIVES: Disease flares in the post-coronavirus disease 2019 (COVID-19) vaccination period represent a prominent concern, though risk factors are poorly understood. We studied these flares among patients with idiopathic inflammatory myopathies (IIMs) and other autoimmune rheumatic diseases (AIRDs). METHODS: The COVAD-1 and -2 global surveys were circulated in early 2021 and 2022, respectively, and we captured demographics, comorbidities, AIRDs details, COVID-19 infection history and vaccination details. Flares of IIMs were defined as (a) patient self-reported, (b) immunosuppression (IS) denoted, (c) clinical sign directed and (d) with >7.9-point minimal clinically significant improvement difference worsening of Patient-Reported Outcomes Measurement Information System (PROMIS) PROMISPF10a score. Risk factors of flares were analysed using regression models. RESULTS: Of 15 165 total respondents, 1278 IIMs (age 63 years, 70.3% female, 80.8% Caucasians) and 3453 AIRDs were included. Flares of IIM were seen in 9.6%, 12.7%, 8.7% and 19.6% patients by definitions (a) to (d), respectively, with a median time to flare of 71.5 (10.7-235) days, similar to AIRDs. Patients with active IIMs pre-vaccination (OR 1.2; 95% CI 1.03, 1.6, P = 0.025) were prone to flares, while those receiving rituximab (OR 0.3; 95% CI 0.1, 0.7, P = 0.010) and AZA (OR 0.3, 95% CI 0.1, 0.8, P = 0.016) were at lower risk. Female gender and comorbidities predisposed to flares requiring changes in IS. Asthma (OR 1.62; 95% CI 1.05, 2.50, P = 0.028) and higher pain visual analogue score (OR 1.19; 95% CI 1.11, 1.27, P < 0.001) were associated with disparity between self-reported and IS-denoted flares. CONCLUSION: A diagnosis of IIMs confers an equal risk of flares in the post-COVID-19 vaccination period to AIRDs, with active disease, female gender and comorbidities conferring a higher risk. Disparity between patient- and physician-reported outcomes represents a future avenue for exploration.


Assuntos
Doenças Autoimunes , Vacinas contra COVID-19 , COVID-19 , Miosite , Doenças Reumáticas , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Autoimunes/fisiopatologia , COVID-19/prevenção & controle , Vacinas contra COVID-19/efeitos adversos , Miosite/fisiopatologia , Inquéritos e Questionários , Vacinação/efeitos adversos , Progressão da Doença , Doenças Reumáticas/fisiopatologia
5.
Front Plant Sci ; 14: 1280321, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37965010

RESUMO

Introduction: Sheath blight caused by Rhizoctonia solani is one of the major diseases of rice, causing widespread crop losses. The use of semi-dwarf rice varieties in the ongoing nutrient-intensive rice cultivation system has further accentuated the incidence of the disease. An ideal solution to this problem would be identifying a stable sheath blight-tolerant genotype. Material and methods: A multi-environment evaluation of 32 rice genotypes against sheath blight infection was conducted over six seasons across two locations (Agricultural Research Farm, Institute of Agricultural Sciences, Banaras Hindu University (28.18° N, 38.03° E, and 75.5 masl), for four years during the wet seasons (kharif) from 2015 to 2018 and two seasons at the National Rice Research Institute (20°27'09" N, 85°55'57" E, 26 masl), Cuttack, Odisha, during the dry season (rabi) of 2019 and the kharif of 2019, including susceptible and resistant check. Percent disease index data were collected over 4 weeks (on the 7th, 14th, 21st, and 28th day after infection), along with data on other morphological and physiological traits. Result and discussion: The resistant genotypes across seasons were the ones with a higher hemicellulose content (13.93-14.64) and lower nitrogen content (1.10- 1.31) compared with the susceptible check Tapaswini (G32) (hemicellulose 12.96, nitrogen 1.38), which might explain the resistant reaction. Three different stability models-additive main effect and multiplicative interaction (AMMI), genotype + genotype x environment (GGE) biplot, and multi-trait stability index (MTSI)-were then used to identify the stable resistant genotypes across six seasons. The results obtained with all three models had common genotypes highlighted as stable and having a low area under the disease progress curve (AUDPC) values. The ideal stable genotypes with low disease incidence were IC 283139 (G19), Tetep (G28), IC 260917 (G4), and IC 277274 (G10), with AUDPC values of 658.91, 607.46, 479.69, and 547.94, respectively. Weather parameters such as temperature, rainfall, sunshine hours, and relative humidity were also noted daily. Relative humidity was positively correlated with the percent disease index.

6.
Heliyon ; 9(11): e21189, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37954398

RESUMO

The utilization of Maxwell fluid with nanoparticle suspension exhibits promising prospects in enhancing the efficacy of energy conversion and storage mechanisms. They have the potential to be utilized in sophisticated cooling systems for power generation facilities, thereby augmenting the overall energy efficacy. Keeping this in mind, the current research examines the Maxwell nanofluid flow over a rotating disk with the impact of a heat source/sink. The present study centers on the examination of flow characteristics in the existence of a uniform magnetic field. The conversion of governing equations into ordinary differential equations is achieved using appropriate similarity variables. To derive the Nusselt number (Nu) and skin friction (SF) model related to the flow and temperature parameters, the suggested back-propagation artificial neural networking (ANN) technique is used. The Runge-Kutta-Fehlberg fourth-fifth order (RKF-45) method is used to solve the reduced equations and produce the necessary data to create the Nu and SF model. Both the Nu and SF models require 1000 data for training the network, respectively. Graphs are utilized to communicate numerical outcomes. The results concluded that the upsurge in magnetic parameter drops the velocity profile but advances the heat transport. Rise in the thermal conductivity parameter, increases the heat transport.

7.
Nanoscale Adv ; 5(23): 6647-6658, 2023 Nov 21.
Artigo em Inglês | MEDLINE | ID: mdl-38024299

RESUMO

The present research focuses on the significance of thermophoretic particle deposition on a ZnO-SAE50 nanolubricant flow in a stretchable/shrinkable convergent/divergent channel in the presence of an applied magnetic field and nonlinear heat radiation. A parameter in the governing differential equations and wall boundary conditions defines the physical mechanism of the model. The Galerkin finite element method, combined with similarity transformation, is adopted to solve the governing equations. The Levenberg-Marquardt backpropagating algorithm of an artificial neural network model forecasts heat and mass transfer properties. The results reveal that by stretching/shrinking the walls enough, the classical flow and heat properties are significantly affected. The stretching of the convergent or divergent channel is observed to increase the velocity profiles, whilst shrinking results in backflow regions. In terms of the temperature field, stretching causes more heat to be produced in the flow; nevertheless, the thermal layer is decreased and cooling is attained by channel shrinkage, which may have important technical implications.

8.
Nanoscale Adv ; 5(21): 5941-5951, 2023 Oct 24.
Artigo em Inglês | MEDLINE | ID: mdl-37881708

RESUMO

Non-Newtonian fluids have unique heat transfer properties compared to Newtonian fluids. The present study examines the flow of a Maxwell nanofluid across a rotating rough disk under the effect of a magnetic field. Furthermore, the Cattaneo-Christov heat flux model is adopted to explore heat transport features. In addition, a comparison of fluid flow without and with aggregation is performed. Using similarity variables, the governing partial differential equations are transformed into a system of ordinary differential equations, and this system is then solved by employing the Runge-Kutta Fehlberg fourth-fifth order method to obtain the numerical solution. Graphical depictions are used to examine the notable effects of various parameters on velocity and thermal profiles. The results reveal that an increase in the value of Deborah number decreases the velocity profile. An increase in the thermal relaxation time parameter decreases the thermal profile. An artificial neural network is employed to calculate the rate of heat transfer and surface drag force. The R values for skin friction and Nusselt number were computed. The results demonstrate that artificial neural networks accurately predicted skin friction and Nusselt number values.

9.
J Pharm Bioallied Sci ; 15(Suppl 2): S907-S909, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-37694026

RESUMO

The present study was conducted to assess stress distribution around dental implants based on the all-on-four treatment concept. The finite element analysis (FEA) models comprised cancellous bone covered with cortical bone. Four dental implants were placed in two different designs. In model 1, the four implants were placed parallel to each other, whereas, in model 2, the all-on-four concept was followed. The vertical and lateral loads of various values were applied, and stress was evaluated. In model 2, the least stress was observed in both lateral and vertical loading in the peri-implant region. The all-on-four concept proved to be beneficial in reducing the stress around dental implants, thereby reducing the treatment cost.

11.
Photodiagnosis Photodyn Ther ; 43: 103636, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37245682

RESUMO

AIMS AND OBJECTIVES: Assessment of micro tensile bond strength (microTBS) and micro-leakage scores of total-etch adhesive (TAE) and self-etch adhesive (SAE) bonded to carious affected dentin (CAD) sterilized using different cavity disinfectant (curcumin photosensitizer (CP) and malachite green (MG) and Chlorhexidine (CHX) in comparison to no disinfection (ND) control group. MATERIALS AND METHODS: One hundred and twenty human molars having International Caries Detection and Assessment System (ICDAS) scores of 4 and 5 were included. Visual inspection, dental explorer hardness testing, and caries detector solution using 5% basic Fuchsin dye solution was applied to dentin to identify the CAD surface. All the specimens were divided into four groups (n = 30) according to the cavity disinfectants used. Group A: 2% CHX, Group B: CP, Group C: MG, and Group D: ND. Each group was further divided into two subgroups (n = 15) based on the adhesion protocol. Groups A1, B1, C1, and D1 were held using TEA, and groups A2, B2, C2, and D2 were adhered using SEA system. The composite material was then built in 2 mm increments and then cured with light. MicroTBS and failure mode assessment using a universal testing machine (UTM) and stereomicroscope at a 40X magnification was performed on 10 samples from each subgroup. The microleakage assessment was performed using a dye penetration test on five samples from each group. ANOVA and Tukey post-hoc tests were used to compare means and standard deviation (SD) of bond strength and microleakage (p < 0.05). RESULTS The maximum microTBS was displayed by A1= CHX and TEA (13.28± 1.01 MPa). The lowest bond scores were demonstrated by C2= MG and SEA (5.98±0.44 MPa). The highest micro-leakage was exhibited by C1= MG and TEA (58.32 ± 2.11 nm). Whereas, the lowest micro-leakage values were displayed by A2= CHX and SEA (24.34± 1.11 nm). CONCLUSION: Chlorohexidiene displayed better bond strength and the lowest microleakage scores with Total-etch adhesive and Self-etch adhesives when used as a cavity disinfectant. Total-etch adhesives performed better in terms of microTBS scores whereas self-etch adhesives displayed superior seal ability within the same disinfectant group.


Assuntos
Curcumina , Desinfetantes , Fotoquimioterapia , Humanos , Adesivos Dentinários/química , Clorexidina/farmacologia , Adesivos , Fármacos Fotossensibilizantes , Fotoquimioterapia/métodos , Dentina , Teste de Materiais , Resinas Compostas/química
12.
Photodiagnosis Photodyn Ther ; 43: 103605, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37187269

RESUMO

AIM: Evaluation of the push-out bond strength (PBS) of zirconia post-bonded to radicular dentin after using different final irrigants (MTAD, Malachite green (MG), Ti-sapphire laser and Salvadora persica (S.persica). MATERIAL AND METHOD: Forty human permanent single-rooted were decoronated above the cement-enamel junction. An experienced endodontist performed all the root canal instrumentation using ProTaper universal rotary files. Canals were irrigated using 5.25% NaOCl solution followed by EDTA as a final sterilant. Obturation with gutta-percha using AH Plus sealer was performed. Post-space preparation was completed using Gates Glidden and specimens were randomly assigned to four groups based on the final disinfectant received (n=10). Group 1: 5.25% NaOCl + MTAD, group 2: 5.25% NaOCl + MG, group 3: 5.25% NaOCl +Ti-sapphire laser, and group 4: 5.25% NaOCl + S. persica. The chemically polymerized resin was used to lute zirconia posts. PBS and failure mode analysis were performed using a universal testing machine and stereomicroscope at 40X magnification. Data were compared between the two groups with 95% CI using one-way analysis of variance (ANOVA) with the Tukey post hoc test. p=0.05. RESULTS: Group4(5.25% NaOCl+ S.persica) specimens demonstrated the maximum (8.94±0.14 MPa) bond strength. Conversely, the apical third of Group 2 (5.25% NaOCl+ MG) (2.87±0.15 MPa) samples revealed the minimum bond strength scores. Intergroup comparison exposed that Group 1 (1.3% NaOCl+ MTAD), Group 3 (5.25% NaOCl+Ti-sapphire laser), and Group 4 (5.25% NaOCl+ S. persica) at all three-thirds unveiled no significant difference in PBS (p<0.05). CONCLUSION: Ti-sapphire laser and Salvedora Persica possess the potential to be used as a final root canal irrigant to improve the push-out bond strength of zirconia post-to-root dentin.


Assuntos
Fotoquimioterapia , Materiais Restauradores do Canal Radicular , Humanos , Resinas Epóxi , Óxido de Alumínio , Ácido Edético , Fotoquimioterapia/métodos , Fármacos Fotossensibilizantes , Titânio , Lasers , Dentina , Irrigantes do Canal Radicular , Teste de Materiais , Cavidade Pulpar , Preparo de Canal Radicular
14.
Rheumatology (Oxford) ; 62(10): 3291-3301, 2023 10 03.
Artigo em Inglês | MEDLINE | ID: mdl-36734536

RESUMO

OBJECTIVE: COVID-19 vaccines have a favorable safety profile in patients with autoimmune rheumatic diseases (AIRDs) such as idiopathic inflammatory myopathies (IIMs); however, hesitancy continues to persist among these patients. Therefore, we studied the prevalence, predictors and reasons for hesitancy in patients with IIMs, other AIRDs, non-rheumatic autoimmune diseases (nrAIDs) and healthy controls (HCs), using data from the two international COVID-19 Vaccination in Autoimmune Diseases (COVAD) e-surveys. METHODS: The first and second COVAD patient self-reported e-surveys were circulated from March to December 2021, and February to June 2022 (ongoing). We collected data on demographics, comorbidities, COVID-19 infection and vaccination history, reasons for hesitancy, and patient reported outcomes. Predictors of hesitancy were analysed using regression models in different groups. RESULTS: We analysed data from 18 882 (COVAD-1) and 7666 (COVAD-2) respondents. Reassuringly, hesitancy decreased from 2021 (16.5%) to 2022 (5.1%) (OR: 0.26; 95% CI: 0.24, 0.30, P < 0.001). However, concerns/fear over long-term safety had increased (OR: 3.6; 95% CI: 2.9, 4.6, P < 0.01). We noted with concern greater skepticism over vaccine science among patients with IIMs than AIRDs (OR: 1.8; 95% CI: 1.08, 3.2, P = 0.023) and HCs (OR: 4; 95% CI: 1.9, 8.1, P < 0.001), as well as more long-term safety concerns/fear (IIMs vs AIRDs - OR: 1.9; 95% CI: 1.2, 2.9, P = 0.001; IIMs vs HCs - OR: 5.4 95% CI: 3, 9.6, P < 0.001). Caucasians [OR 4.2 (1.7-10.3)] were likely to be more hesitant, while those with better PROMIS physical health score were less hesitant [OR 0.9 (0.8-0.97)]. CONCLUSION: Vaccine hesitancy has decreased from 2021 to 2022, long-term safety concerns remain among patients with IIMs, particularly in Caucasians and those with poor physical function.


Assuntos
Doenças Autoimunes , COVID-19 , Miosite , Doenças Reumáticas , Humanos , Vacinas contra COVID-19/efeitos adversos , Hesitação Vacinal , COVID-19/epidemiologia , COVID-19/prevenção & controle , Miosite/epidemiologia , Autorrelato , Vacinação
15.
Clin Rheumatol ; 42(5): 1339-1349, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-36759401

RESUMO

INTRODUCTION: YouTube is the second most popular search website worldwide to access health information online. This study was undertaken to assess the reliability and quality of information about myositis on YouTube and delineate attributes of useful videos using standard metrics. METHODS: We conducted a thorough search on YouTube using 9 search terms related to myositis. The inclusion criteria were content related to myositis, English language and acceptable audio-video quality. Duplicates and advertisements were excluded from the analysis. Videos were classified as useful, not very useful or misleading and patient narratives. Reliability was determined using the mDISCERN criteria, quality using the Global Quality Scale (GQS) and JAMA system, using appropriate cut-offs (mDISCERN > 4, GQS > 4, JAMA > 3). RESULTS: Out of a total of 900 videos, 453 were included for the analysis. Seventy-four per cent and 2% provided useful and not very useful information respectively, while 24% were patient narratives. Seventy-one per cent were intended specifically for patients while 69% were for healthcare providers and students. Noteworthily, useful and not very useful videos had similar total views though the number of likes and daily viewership were higher for useful videos (p = 0.024, p = 0.046). Nearly half (47%) of useful videos were by professional medical societies/patient support groups (PSGs) while not very useful ones were by nonmedical media (38%). Physician-predicted usefulness was discordant with score-based usefulness (κ = 0.129). However, GQS emerged as a significant (p = 0.008) predictor of video usefulness in multivariate analysis. CONCLUSION: A large majority of English YouTube videos on myositis provide useful information for patients. Physicians could signpost patients to high-quality useful videos as determined by GQS and sources like professional medical societies and PSGs. Key Points •This study highlights the importance of regulating health information posted online, accessed by millions of people, to gauge the quality of information and to identify and curb misinformation. •It also identifies recommendations for the future for uploading such content on the Internet. •The implications lie in our patients being better informed about their disease as they are important stakeholders in the healthcare decision-making process.


Assuntos
Médicos , Mídias Sociais , Humanos , Disseminação de Informação , Reprodutibilidade dos Testes , Comunicação
17.
Sci Rep ; 12(1): 21733, 2022 12 16.
Artigo em Inglês | MEDLINE | ID: mdl-36526629

RESUMO

Hybrid nanofluids' enhanced thermophysical properties make them applicable in a plethora of mechanical and engineering applications requiring augmented heat transfer. The present study focuses on a three-dimensional Copper-Aluminium Oxide [Formula: see text]-water based hybrid nanofluid flow within the boundary layer with heat transfer over a rotating exponentially stretching plate, subjected to an inclined magnetic field. The sheet rotates at an angular velocity [Formula: see text] and the angle of inclination of the magnetic field is [Formula: see text]. Employing a set of appropriate similarity transformation reduces the governing PDEs to ODEs. The resulting ODEs are solved with the finite difference code with Shooting Technique. Primary velocity increases at large rotation but the secondary velocity reduces as the rotation increases. In addition, the magnetic field is found to oppose the flow and thereby causing a reduction in both the primary and secondary velocities. Increasing the volume fraction reduces the skin friction coefficient and enhances the heat transfer rate.


Assuntos
Placas Ósseas , Força Coriolis , Alumínio , Água
18.
Sci Rep ; 12(1): 19188, 2022 Nov 10.
Artigo em Inglês | MEDLINE | ID: mdl-36357473

RESUMO

Chirps are familiar in nature, have a built-in resistance to noise and interference, and are connected to a wide range of highly oscillatory processes. Detecting chirp oscillating patterns by traditional Fourier series is challenging because the chirp frequencies constantly change over time. Estimating such types of functions considering the partial sums of a Fourier series in Fourier analysis does not permit an approximate solution, which entails more Fourier coefficients required for signal reconstruction. The standard Fourier series, therefore, has a poor convergence rate and is an inadequate approximation. In this study, we use a parameterized orthonormal basis with an adjustable parameter to match the oscillating behavior of the chirp to approximate linear chirps using the partial sums of a generalized Fourier series known as fractional Fourier series, which gives the best approximation with only a small number of fractional Fourier coefficients. We used the fractional Fourier transform to compute the fractional Fourier coefficients at sample points. Additionally, we discover that the fractional parameter has the best value at which fractional Fourier coefficients of zero degrees have the most considerable magnitude, leading to the rapid decline of fractional Fourier coefficients of high degrees. Furthermore, fractional Fourier series approximation with optimal fractional parameters provides the minimum mean square error over the fractional Fourier parameter domain.

19.
J Adv Pharm Technol Res ; 13(3): 221-225, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35935690

RESUMO

Observations have suggested that during the coronavirus disease 2019 pandemic, because of lockdown students who are in process of doing their thesis related work exhibit responses related to stress due to the fear of spread contagion and because of various limitations in performing thesis work, especially patient-oriented collection of data and clinical work. The present study aimed to determine various problems faced by the students in postgraduate courses for completing their thesis during pandemic. This was a prospective and cross-sectional study based on a questionnaire. This study was comprised of a total sample size of 300 postgraduate students of different disciplines in the health stream. The study was conducted between June 2021 and December 2021. The prepared study questionnaire was sent to postgraduates by use of electronic mail. Of the total selected students, 280 had responded with complete answers to the questionnaire. Collected data were entered into a Microsoft Excel sheet and analyzed for percentage distribution. 50.7% of postgraduates were found in the age range of 26-30 years, 73.1% were female and 35.6% were in their final year of postgraduation. It was seen that 6.5% were unable to procure ethical approval due to the pandemic, and 43.1% were not able to get permission from the board due to the sudden pandemic. 64.9% were unable to collect data for their thesis, and 18% were unable to report to supervisors. 86.9% of postgraduates suffered from anxiety due to the inability to perform thesis work. 78.9% of postgraduate students had a decrease in motivation for a thesis and 89.1% suffered from anxiety. Due to the ongoing pandemic, postgraduate students are facing many problems in completing their thesis work. This resulted in anxiety and stress themselves.

20.
Photodiagnosis Photodyn Ther ; 40: 103026, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-35872354

RESUMO

AIM: The present study aimed to assess the bond integrity of curcumin photosensitizer (CPS) Photodynamic therapy (PDT) on fiber post disinfection bonded to radicular dentin in comparison to the conventional fiber post sterilant used. MATERIALS AND METHODS: Fifty human permanent single-rooted premolars were utilized with the crown part sectioned using up to the cementoenamel junction. Root canal preparation was performed followed by canal obturation with gutta-percha (GP) and resin-based sealer. The post space was prepared using peso reamers leaving 4 mm at the apical part of the post space. Fifty glass fiber posts (GFP) were divided into five groups based on the surface disinfectant (n = 10). group 1: Autoclave sterilization (AS) group 2: chlorhexidine digluconate (CHX dig), group 3: CPS solution, group 4: 35% phosphoric acid (PA) gel, and group 5: No disinfection. Cementation was performed using dual-cure self-etch resin cement. Each tooth was sectioned and placed on the universal testing machine. Failure mode was analyzed using a stereomicroscope at 40x magnification. Statistical analysis was performed using one-way analysis of variance (ANOVA) and Tukey multiple comparison tests. (p = 0.05). RESULTS: Intragroup comparison analysis demonstrated that group 2 in which 2% CHX dig was used as a post-surface disinfectant revealed the highest bond integrity at all three levels. Group 5 where no disinfectant was used to decontaminate the post surface exhibited the lowest bond values. In all the investigated groups, PBS values showed a downward trend from coronal to the apical third of the post space. Group 1 in which AS was used to sterilize the fiber post and group 3 in which CPS was smeared to decontaminate the GFPs surface-displayed comparable outcomes of PBS to group 5 specimens at all three levels. (p > 0.05). CONCLUSION: CHX dig and PA post-surface disinfection displayed a positive impact on bond strength with the radicular dentin. However, CPS and AS do not reveal any effect on the PBS when used for post-decontamination.


Assuntos
Fotoquimioterapia , Técnica para Retentor Intrarradicular , Humanos , Dentina , Teste de Materiais , Fotoquimioterapia/métodos , Cavidade Pulpar
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