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1.
J Environ Manage ; 356: 120611, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38508014

RESUMO

Microalgae represent a promising renewable feedstock for the sustainable production of biohydrogen. Their high growth rates and ability to fix carbon utilizing just sunlight, water, and nutrients make them well-suited for this application. Recent advancements have focused on improving microalgal hydrogen yields and cultivation methods. This review aims to summarize recent developments in microalgal cultivation techniques and genetic engineering strategies for enhanced biohydrogen production. Specific areas of focus include novel microalgal species selection, immobilization methods, integrated hybrid systems, and metabolic engineering. Studies related to microalgal strain selection, cultivation methods, metabolic engineering, and genetic manipulations were compiled and analyzed. Promising microalgal species with high hydrogen production capabilities such as Synechocystis sp., Anabaena variabilis, and Chlamydomonas reinhardtii have been identified. Immobilization techniques like encapsulation in alginate and integration with dark fermentation have led to improved hydrogen yields. Metabolic engineering through modulation of hydrogenase activity and photosynthetic pathways shows potential for enhanced biohydrogen productivity. Considerable progress has been made in developing microalgal systems for biohydrogen. However, challenges around process optimization and scale-up remain. Future work involving metabolic modeling, photobioreactor design, and genetic engineering of electron transfer pathways could help realize the full potential of this renewable technology.


Assuntos
Microalgas , Microalgas/metabolismo , Biocombustíveis , Fermentação , Fotobiorreatores , Hidrogênio/análise , Biomassa
2.
Int J Nanomedicine ; 18: 6601-6638, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38026521

RESUMO

The necessity to engineer sustainable nanomaterials for the environment and human health has recently increased. Due to their abundance, fast growth, easy cultivation, biocompatibility and richness of secondary metabolites, algae are valuable biological source for the green synthesis of nanoparticles (NPs). The aim of this review is to demonstrate the feasibility of using algal-based NPs for cancer treatment. Blue-green, brown, red and green micro- and macro-algae are the most commonly participating algae in the green synthesis of NPs. In this process, many algal bioactive compounds, such as proteins, carbohydrates, lipids, alkaloids, flavonoids and phenols, can catalyze the reduction of metal ions to NPs. In addition, many driving factors, including pH, temperature, duration, static conditions and substrate concentration, are involved to facilitate the green synthesis of algal-based NPs. Here, the biosynthesis, mechanisms and applications of algal-synthesized NPs in cancer therapy have been critically discussed. We also reviewed the effective role of algal synthesized NPs as anticancer treatment against human breast, colon and lung cancers and carcinoma.


Assuntos
Nanopartículas Metálicas , Nanopartículas , Neoplasias , Humanos , Nanopartículas/química , Plantas/química , Nanopartículas Metálicas/uso terapêutico , Nanopartículas Metálicas/química , Neoplasias/tratamento farmacológico
3.
Environ Sci Pollut Res Int ; 30(53): 113119-113137, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37851256

RESUMO

Currently, sustainable agriculture involves ecofriendly techniques, which include biofertilization. Biofertilizers increase plant productivity by improving soil fertility and nutrient content. A wide range of living organisms can be applied as biofertilizers and increase soil fertility without causing pollution due to their biodegradability. The organisms can be microorganisms like bacteria, microalgae, and micro fungi or macro organisms like macroalgae, macro fungi, and higher plants. Biofertilizers extracted from living organisms or their residues will be increasingly used rather than chemical fertilizers, which cause heavy metal accumulation in soil. Biofertilizer use aims for sustainable development in agriculture by maintaining the soil. This will mitigate climate change and related impacts and will also lower many serious diseases resulting from pollution such as cancer, liver and renal failure, and immune diseases. This review is a comprehensive overview of biofertilizers extracted from a range of living organisms from the Kingdoms Monera to Plantae and included bacteria, algae, fungi, and higher plants. Organisms that play a vital role in elevating soil nutrients in a safe, cheap, and ecofriendly manner are included in the review to promote their potential commercial application.


Assuntos
Agricultura , Fertilizantes , Fertilizantes/análise , Agricultura/métodos , Solo/química , Bactérias , Microbiologia do Solo , Fungos , Plantas/microbiologia
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