RESUMO
We present a case report of a three-year old patient diagnosed with retinoblastoma in her left eye. The course of the disease made enucleation of the latter eye and a prosthesis implant necessary. Two years after surgery, partial prosthesis extrusion occurred and a semisynthetic dura mater substitute was used as a patch graft to cover the defect. To our knowledge, semisynthetic dura mater substitutes' use in this scenario has not been previously reported.
Assuntos
Anoftalmia/cirurgia , Dura-Máter , Enucleação Ocular , Próteses e Implantes , Neoplasias da Retina/cirurgia , Retinoblastoma/cirurgia , Pré-Escolar , Feminino , HumanosRESUMO
A 55-year-old male presented with an infectious keratitis in his left eye, affecting one of the incisions of the radial keratotomy he had undergone thirty-four years ago. Suturing the incision with two simple interrupted stitches was key to the resolution of the infection. Floppy eyelid syndrome was also found in this patient. Could this act as a risk factor for infectious keratitis in radial keratotomy? To our knowledge, this is the first reported case describing the association between both conditions, and the second reported case where sutures have been used as an adjuvant treatment in these types of cases.
Assuntos
Blefaroptose/complicações , Ceratoconjuntivite Infecciosa/etiologia , Ceratotomia Radial/efeitos adversos , Infecções Estafilocócicas/etiologia , Staphylococcus epidermidis/isolamento & purificação , Infecção da Ferida Cirúrgica/etiologia , Técnicas de Sutura , Animais , Antibacterianos/uso terapêutico , Desbridamento , Quimioterapia Combinada , Humanos , Ceratoconjuntivite Infecciosa/tratamento farmacológico , Ceratoconjuntivite Infecciosa/cirurgia , Masculino , Pessoa de Meia-Idade , Infecções Estafilocócicas/tratamento farmacológico , Infecções Estafilocócicas/cirurgia , Infecção da Ferida Cirúrgica/tratamento farmacológico , Infecção da Ferida Cirúrgica/cirurgia , Fatores de Tempo , Uveíte Anterior/tratamento farmacológico , Uveíte Anterior/etiologia , Uveíte Anterior/cirurgiaRESUMO
Dupilumab is a drug that has recently been approved by the Food and Drug Administration (FDA) and European Medical Agency (EMA) for the treatment of moderate-to-severe atopic dermatitis in adults. An increase in frequency of conjunctivitis related to dupilumab treatment has been reported in recent publications and clinical trials. We report two steroid-dependent cases satisfactorily treated with cyclosporine 0.1% (Ikervis®). To our knowledge there are no reported cases of dupilumab-associated conjunctivitis treated with cyclosporine 0.1% (Ikervis®).
Assuntos
Anticorpos Monoclonais Humanizados/efeitos adversos , Conjuntivite/induzido quimicamente , Conjuntivite/tratamento farmacológico , Ciclosporina/uso terapêutico , Dermatite Atópica/tratamento farmacológico , Imunossupressores/uso terapêutico , Corticosteroides/uso terapêutico , Adulto , Conjuntivite/diagnóstico por imagem , Feminino , Fluormetolona/uso terapêutico , Glucocorticoides/uso terapêutico , Humanos , Subunidade alfa de Receptor de Interleucina-4 , Masculino , Pessoa de Meia-Idade , RecidivaRESUMO
A 44 year-old Caucasian male with a history of plaque psoriasis currently being treated with ustekinumab presented with sudden loss of vision in his left eye. Fundus examination showed central retinal vein occlusion coexisting with central retinal artery occlusion. Posterior examination revealed mild polycythemia, being the underlying cause unknown.
Assuntos
Psoríase/complicações , Oclusão da Artéria Retiniana/etiologia , Oclusão da Veia Retiniana/etiologia , Adulto , Fármacos Dermatológicos/uso terapêutico , Humanos , Masculino , Psoríase/tratamento farmacológico , Oclusão da Artéria Retiniana/complicações , Oclusão da Veia Retiniana/complicações , Ustekinumab/uso terapêuticoRESUMO
A 17 year-old Caucasian female presented with decreased vision, with no other symptoms reported at that time. Ophthalmological examination revealed typical signs of hypertensive choroidopathy, Elschnig spots, and Siegrist streaks. Further medical examination found high blood pressure (220/155mmHg), with a metastatic hormone-secreting adrenal carcinoma being the underlying cause of these alterations. To our knowledge, this is the first reported case of hypertensive choroidopathy associated with adrenal carcinoma.