Gum Arabic as a potential candidate in quorum quenching and treatment of periodontal diseases.

Periodontal diseases are chronic inflammatory conditions influenced by bacterial biofilm formation and host immune responses, affecting millions worldwide. Traditional treatments like mechanical debridement and systemic antibiotics often face limitations, including biofilm resilience and antibiotic resistance. Gum Arabic (GA), a natural exudate from Acacia trees, presents a promising alternative with its anti-biofilm and anti-inflammatory properties. This review highlights the role of GA in periodontal therapy, particularly its ability to interfere with quorum sensing (QS) pathways, specifically the AI-2 signaling system used by key periodontal pathogens such as Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Fusobacterium nucleatum. By disrupting QS, GA inhibits biofilm formation, reduces bacterial virulence, and promotes a balanced oral microbiome. GA's prebiotic properties also encourage the growth of beneficial bacteria, enhancing the host's immune response while preserving the systemic microbiome. Clinical studies demonstrate GA's effectiveness as an adjunct in periodontal therapy, with significant reductions in plaque accumulation, gingival inflammation, and bleeding. This highlights GA's potential as a natural therapeutic agent, offering an effective, antibiotic-sparing option in managing periodontal disease. However, further research is warranted to fully establish GA's role in comprehensive periodontal care and its long-term benefits.

Computer aided design/computer aided manufacturing (CAD/CAM) technology in the undergraduate dental programs in the MENA region.

INTRODUCTION: The aim of this study was to understand the trends of teaching Computer Aided Design/Computer Aided Manufacturing (CAD/CAM) in the undergraduate dental curriculum in the MENA region by conducting an online survey among the undergraduate dental colleges in this region. MATERIALS AND METHODS: An online survey was conducted using Google Forms consisting of 20 questions that could be answered by "yes" or "no" responses, multiple-choice answers or in a descriptive, "open" format. A total of 55 participants from the MENA region representing their dental college were requested to participate in this study. RESULTS: The response rate of the survey was 85.5% following the twofold follow-up reminders method. Although the vast majority of professors demonstrated vital knowledge in the practical use of CAD/CAM, the majority of them did not provide theoretical and practical training on CAD/CAM in their institutions. Among the schools with established levels of teaching CAD/CAM, nearly 50% of them provide both pre-clinical and clinical training on CAD/CAM. Despite the availability of extra-curricular training courses on CAD/CAM outside the university setting, there is a lack of advocating for students to enrol in those courses by the institutions. More than 80% of the participants agreed that CAD/CAM has a strong future in chair-side dental clinics and CAD/CAM needs to be incorporated within undergraduate studies. CONCLUSION: Based on the results of the current study, it is understandable that an intervention is required by the dental education providers to cope with the growing demand for CAD/CAM technology for the current and future dental practitioners of the MENA region.

The Blending Effect of Single-Shade Composite with Different Shades of Conventional Resin Composites-An In Vitro Study.

OBJECTIVES: Single-shade composite systems are gaining popularity among clinicians due to the claimed potential of blending with different tooth structure shades while restoring the tooth. The purpose of this study was to evaluate the blending effect of two single-shade composite with different shades of conventional resin composite systems. MATERIALS AND METHODS: Seventy-two composite cylinders of B1, B2, A1, A2, A3, or A3.5 shade from CharmFil Plus (CP) and Filtek Universal Restorative (3M) were prepared using custom-made silicone mold. Single-shade composite OMNICHROMA (OC) or Beautifil II Enamel (BE) was placed in the center of each cylinder and polymerized. The color parameters, lightness (L*), chroma (C*), and hue (H*) of each composite were measured using a color chronometer. Furthermore, color stability of the samples was evaluated after 1-week staining challenge. STATISTICAL ANALYSIS: Multivariant analysis was performed to evaluate the effect of material and shade on the color parameters. Multiple comparisons of the data were performed using post hoc test. The staining challenge data were analyzed using repeated measure analysis of variance and paired sample T-test. RESULTS: The multivariant analysis showed a statistically significant difference in color parameters among CP, 3M, OC, and BE (p = 0.001). Image analysis showed a visual blending effect for both OC and BE for certain shades; however, some color contrast with the darker shades was observed. The C* value of OC showed a similar pattern to CP; however, the H* of the latter was closely followed by BE. The L* value showed statistically significant difference among the shades of 3M, and in OC and BE when blended with 3M. CONCLUSION: All four materials used in this study showed color alteration after the staining challenge. Single-shade composite can blend with only certain shades of resin composites.