RESUMO
Given the importance of COVID-19-induced ARDS, recently, researchers have strived to determine underlying mechanisms involved in the inflammatory responses. In this regard, inflammasomes possess a distinct priority for cytokine storm occurrence and, subsequently, ARDS progression in ill patients with SARS-CoV-2 infection. In this minireview, the characteristics of known inflammasome inhibitors and designed research in this field were concretely deciphered.
Assuntos
COVID-19 , Síndrome do Desconforto Respiratório , Humanos , COVID-19/complicações , Inflamassomos , SARS-CoV-2 , Proteína 3 que Contém Domínio de Pirina da Família NLR , Síndrome do Desconforto Respiratório/tratamento farmacológicoRESUMO
In the following, we report a therapeutic challenge faced by reduction in corticosteroid therapeutic dosage in a patient diagnosed with Hashimoto's encephalopathy (HE), which is equivalent to corticosteroid-responsive encephalopathy related to autoimmune thyroiditis and often misdiagnosed as neuropsychiatric status. The patient developed psychiatric symptoms.