Acute Toxicity, Hematological Profile, and Histopathological Effects of MgO Nanoparticles on Gills, Muscle, Liver of Mrigal, Cirrhinus mrigala.

Nanotechnology is an advancing and emerging field of all environmental, medical, and industrial applications. Magnesium oxide nanoparticles have been widely used in medicine, consumer products, industrial products, textiles, ceramics, alleviation of heartburn, stomach ulcers, and bone regeneration. In the present study, acute toxicity (LC50) of MgO nanoparticles and hematological and histopathological changes in Cirrhinus mrigala was analyzed. The lethal concentration for 50% of MgO nanoparticles was 4.2321 mg/L. Hematological parameters such as white blood cells, red blood cells, hematocrit, hemoglobin, platelets, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration, as well as histopathological abnormalities in gills, muscle, and liver were observed on the 7th and 14th days of exposure. The WBC, RBC, HCT, Hb, and platelets count increased on the 14th day of exposure compared to the control and 7th day of exposure. The MCV, MCH, and MCHC levels decreased on the 7th day of exposure compared to the control and increased on the 14th day. Histopathological changes of MgO nanoparticles in gills, muscle, and liver highly damaged in the quantity of 3.6 mg/L compared to 12 mg/L on 7th and 14th days of exposure. This study finds the level of exposure in hematology and histopathological changes in tissues in relation to the exposure of MgO NPs.

Current risks of microbial infections in fish and their prevention methods: A review.

A fast-expanding sector of agriculture worldwide is aquaculture. The production of fish internationally accounts for around 44 % of the total. Even though the aquaculture environment presents several difficulties, the current development in aquaculture production comes with an increase in infectious diseases, which significantly impacts the production, profitability, and sustainability of the worldwide aquaculture business. Many infectious agents, such as bacteria, viruses, fungi and parasites are causative agents for fish infections. Most infectious diseases found in all types of fish like marine water, freshwater and ornamental fishes are caused by bacteria, with many of them serving as secondary opportunistic invaders that attack sick animals by affecting their natural host immunity. To overcome this, addressing health issues based on methods that have been scientifically verified and advised will help lessen the effects of fish disease. This review aims to highlight some of the common microbial-infecting agents of fish in all types of aquatic systems and their effective methods for preventing infections in aquaculture.

Impact of acute and sub-acute exposure of magnesium oxide nanoparticles on mrigal Cirrhinus mrigala.

This experiment was conducted to investigate the impact of acute and sub-acute exposure of magnesium oxide nanoparticles on Mrigal Cirrhinus mrigala. For sub-acute tests 1/100,1/50,1/10 were selected based on the LC50 at 96 h s. Protein, carbohydrate, and lipid, Aspartate aminotransferase, alanine transaminase, lactate dehydrogenase and DPPH, HRSA assays were analyzed in the gill, muscle, and liver of Mrigal. Protein and lipid levels increased on the 7th,14th day compared to control. Carbohydrate levels decreased on the 7th,14th day of exposure, and the enzymatical changes increased on the 7th,14th day. Antioxidant levels highly increased in DPPH assay compared to the HRSA assay. This study provides the biochemical, antioxidant, and behavioral changes in relation to the exposure of MgO NPs.